Hand gesture recognition for player control

Lan Yan Shi,김진규(Jin Gyu Kim),염동회(Dong Hae Yeom),주영훈(Young Hoon Joo) 대한전기학회 2011 대한전기학회 학술대회 논문집 Vol.2011 No.7

Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats

Yan Lan,Huan-Jun Lu,Xian Jiang,Li-Wei Li,Yan-Zhao Yang,Guang-Shi Jin,박주영,김민선,박병림,Yuan-Zhe Jin 대한약리학회 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.2

Input signals originating from baroreceptors and vestibular receptors are integrated in the rostralventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contributionof baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotensionwere quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase(pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate releasein the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL)and/or sinoaortic denervation (SAD) following hypotension induced by a sodium nitroprusside (SNP)infusion. The expression of pERK was significantly increased in the RVLM in the control groupfollowing SNP infusion, and expression peaked 10 min after SNP infusion. The number of pERKpositive neurons increased following SNP infusion in BL, SAD, and BL+SAD groups, although theincrease was smaller than seen in the control group. The SAD group showed a relatively higherreduction in pERK expression when compared with the BL group. The level of glutamate release wassignificantly increased in the RVLM in control, BL, SAD groups following SNP infusion, and thispeaked 10 min after SNP infusion. The SAD group showed a relatively higher reduction in glutamaterelease when compared with the BL group. These results suggest that the baroreceptors are morepowerful in pERK expression and glutamate release in the RVLM following hypotension than thevestibular receptors, but the vestibular receptors still have an important role in the RVLM.

Local Hyperthermia Affects Murine Contact Hypersensitivity around Elicitation Phase

( Yan Sun ),( Lan Zhang ),( Qian An ),( Yuxiao Hong ),( Yan Wu ),( Xinghua Gao ) 대한피부과학회 2018 Annals of Dermatology Vol.30 No.1

Effect of high temperature on the bond performance between steel bars and recycled aggregate concrete

Lan-Lan Yan,Jiong-Feng Liang,Yan-gang Zhao 사단법인 한국계산역학회 2019 Computers and Concrete, An International Journal Vol.23 No.3

The use of recycled aggregate concrete for the purpose of environmental and resource conservation has gained increasing interest in construction engineering. Nevertheless, few studies have reported on the bonding performance of the bars in recycled aggregate concrete after exposed to high temperatures. In this paper, 72 pull-out specimens and 36 cubic specimens with different recycled coarse aggregate content (i.e., 0%, 50%,100%) were cast to evaluate the bond behavior between recycled aggregate concrete and steel bar after various temperatures (20°C, 200°C, 400°C, 600°C). The results show that the recycled aggregate concrete pull-out specimens exhibited similar bond stress-slip curves at both ambient and high temperature. The bond strength declined gradually with the increase of the temperature. On the basis of a regression analysis of the experimental data, a revised bond strength mode and peak slip ratios relationship model were proposed to predict the post-heating bond-slip behavior between recycled aggregate concrete and steel bar.

Use of waste glass as coarse aggregate in concrete: mechanical properties

Yan, Lan-lan,Liang, Jiong-Feng Techno-Press 2019 Advances in concrete construction Vol.8 No.1

The possibility of using recycled coarse glass aggregates as a substitute for natural crushed stone are relatively limited. In order to promote it for engineering application, this paper reports the effect of coarse glass aggregate on mechanical behavior of concrete. The coarse aggregates are substituted for coarse glass aggregate (CGA) as 0%,20%,40%,60%,80% and 100%.The results show that increasing the coarse glass aggregate content cause decrease in compressive strength, the elastic modulus, the splitting tensile strength, the flexural strength. An equation is presented to generate the relationship between cube compressive strength and prism compressive strength, the relationship between cube compressive strength and elastic modulus, the relationship between cube compressive strength and splitting tensile strength, the relationship between cube compressive strength and flexural strength of coarse glass concrete.

Analysis of the Baroreceptor and Vestibular Receptor Inputs in the Rostral Ventrolateral Medulla following Hypotension in Conscious Rats

Lan, Yan,Lu, Huan-Jun,Jiang, Xian,Li, Li-Wei,Yang, Yan-Zhao,Jin, Guang-Shi,Park, Joo Young,Kim, Min Sun,Park, Byung Rim,Jin, Yuan-Zhe The Korean Society of Pharmacology 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.2

Input signals originating from baroreceptors and vestibular receptors are integrated in the rostral ventrolateral medulla (RVLM) to maintain blood pressure during postural movement. The contribution of baroreceptors and vestibular receptors in the maintenance of blood pressure following hypotension were quantitatively analyzed by measuring phosphorylated extracellular regulated protein kinase (pERK) expression and glutamate release in the RVLM. The expression of pERK and glutamate release in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or sinoaortic denervation (SAD) following hypotension induced by a sodium nitroprusside (SNP) infusion. The expression of pERK was significantly increased in the RVLM in the control group following SNP infusion, and expression peaked 10 min after SNP infusion. The number of pERK positive neurons increased following SNP infusion in BL, SAD, and BL+SAD groups, although the increase was smaller than seen in the control group. The SAD group showed a relatively higher reduction in pERK expression when compared with the BL group. The level of glutamate release was significantly increased in the RVLM in control, BL, SAD groups following SNP infusion, and this peaked 10 min after SNP infusion. The SAD group showed a relatively higher reduction in glutamate release when compared with the BL group. These results suggest that the baroreceptors are more powerful in pERK expression and glutamate release in the RVLM following hypotension than the vestibular receptors, but the vestibular receptors still have an important role in the RVLM.

Association of the Single-Nucleotide Polymorphism and Haplotype of the Complement Receptor 1 Gene with Malaria

Yan Lan,Le-Gen Nong,Chuan-Dong Wei,Wen-Cheng Chen,Jun-Li Wang,Chun-Fang Wang,Guo-Gang Pan,Ye-Sheng Wei 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.2

Purpose: Although the polymorphisms of erythrocyte complement receptor type 1 (CR1) in patients with malaria have been extensively studied, a question of whether the polymorphisms of CR1 are associated with severe malaria remains controversial. Furthermore, no study has examined the association of CR1 polymorphisms with malaria in Chinese population. Therefore, we investigated the relationship of CR1 gene polymorphism and malaria in Chinese population. Materials and Methods:We analyzed polymorphisms of CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T in 509 patients with malaria and 503 controls, using the Taqmangenotyping assay and PCR-direct sequencing. Results: There were no significantdifferences in the genotype, allele and haplotype frequencies of CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms between patientswith malaria and controls. Furthermore, there was no association of polymorphismsin the CR1 gene with the severity of malaria in Chinese population. Conclusion:These findings suggest that CR1 gene rs2274567 G/A, rs4844600 G/A, and rs2296160 C/T polymorphisms may not be involved in susceptibility to malariain Chinese population.

Association between the MDM2 T309G Polymorphism and Leukemia Risk: a Meta-analysis

Yan, Yu-Lan,Han, Feng,Tan, Wen-Min,Wu, Cui-Ping,Qin, Xi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

Several studies have suggested associations between MDM2 (mouse double minute 2 homolog) polymorphisms and leukemia risk, but they reported contradictory results. For better understanding of the effect of MDM2 T309G polymorphism on leukemia risk, we performed a meta-analysis. All eligible studies were identified through a search of PubMed, Web of Science, EMBASE, and Chinese Biomedical Literature (CBM) databases before May 2014. Assessment of associations between the MDM2 T309G polymorphism and leukemia risk was conducted by odds ratios (ORs) and 95% confidence intervals (95% CIs). Finally, a total of 11 publications covering 12 case-control studies with 2, 362 cases and 5, 562 controls concerning MDM2 T309G polymorphism with respect to leukemia were included in the meta-analysis. Significant associations were found between MDM2 T309G polymorphism and leukemia risk in four models in overall populations (G vs T: OR=1.29, 95% CI=1.11-1.49, p=0.001; GG vs TT: OR=1.67, 95% CI=1.21-2.30, p=0.002; GG vs TG/TT: OR=1.56, 95% CI=1.21-2.00, p=0.001; GG/TG vs TT: OR=1.28, 95% CI=1.05-1.57, p=0.015). In the sub-group analysis according to ethnicity, increased leukemia risks were observed in three genetic models among Asians but not Caucasians. In conclusion, the results of our meta-analysis suggest that the MDM2 T309G polymorphism can increase the risk of leukemia, especially among Asian populations.

Additive Role of the Vestibular End Organ and Baroreceptors on the Regulation of Blood Pressure in Rats

Yan Lan,Yan-Zhao Yang,Xian Jiang,Guang-Shi Jin,김민선,박병림,Yuan-Zhe Jin,Li-Wei Li 대한약리학회 2013 The Korean Journal of Physiology & Pharmacology Vol.17 No.4

Contribution of the vestibular end organ to regulation of arterial pressure was quantitatively compared with the role of baroreceptors in terms of baroreflex sensitivity and c-Fos protein expression in the rostral ventrolateral medulla (RVLM). Baroreflex sensitivity and c-Fos protein expression in the RVLM were measured in conscious rats that had undergone bilateral labyrinthectomy (BL) and/or baroreceptor unloading. BL attenuated baroreflex sensitivity during intravenous infusion of sodium nitroprusside (SNP), but did not significantly affect the sensitivity following infusion of phenylephrine (PE). Baroreflex sensitivity became positive following sinoaortic denervation (SAD) during infusion of PE and attenuated sensitivity during infusion of SNP. Baroreflex sensitivity also became positive following double ablation (BL+SAD) during infusion of PE, and attenuated sensitivity during infusion of SNP. c-Fos protein expression increased significantly in the RVLM in the sham group after SNP administration. However, the BL, SAD, and SAD+BL groups showed significant decreases in c-Fos protein expression compared with that in the sham group. The SAD group showed more reduced c-Fos protein expression than that in the BL group, and the SAD+BL group showed less expression than that in the SAD group. These results suggest that the vestibular system cooperates with baroreceptors to maintain arterial pressure during hypotension but that baroreceptors regulate arterial pressure during both hypotension and hypertension. Additionally, afferent signals for maintaining blood pressure from the vestibular end organs and the baroreceptors may be integrated in the RVLM.

Salivary Pepsin as an Intrinsic Marker for Diagnosis of Sub-types of Gastroesophageal Reflux Disease and Gastroesophageal Reflux Disease-related Disorders

( Yan-jun Wang ),( Xiu-qiong Lang ),( Dan Wu ),( Yu-qin He ),( Chun-hui Lan ),( Xiao-xiao ),( Bin Wang ),( Duo-wu Zou ),( Ji-min Wu ),( Yong-bin Zhao ),( Peter W Dettmar ),( Dong-feng Chen ),( Min Yan 대한소화기 기능성질환·운동학회 2020 Journal of Neurogastroenterology and Motility (JNM Vol.26 No.1

Background/Aims To determine the value of salivary pepsin in discriminating sub-types of gastroesophageal reflux disease (GERD) and GERD-related disorders. Methods Overall, 322 patients with different sub-types of GERD and 45 healthy controls (HC) were studied. All patients took Gastroesophageal Reflux Disease Questionnaire (GerdQ) and underwent endoscopy and 24-hour esophageal pH monitoring and manometry. Salivary pepsin concentration (SPC) was detected by using colloidal gold double-antibody immunological sandwich assay. Oral esomeprazole treatment was administrated in the patients with non-erosive reflux disease (NERD) and extra-esophageal symptoms (EES). Results Compared to HC, patients with erosive esophagitis, NERD, EES, EES plus typical GERD symptoms, or Barrett’s esophagus had a higher prevalence of saliva and SPC (all P < 0.001). There was no significant difference in the positive rate for pepsin in patients with functional heartburn or GERD with anxiety and depression, compared to HC. After esomeprazole treatment, the positive rate and SPC were significantly reduced in NERD (both P < 0.001) and in EES (P = 0.001 and P = 0.002, respectively). Of the 64 NERD patients, 71.9% (n = 46) were positive for salivary pepsin, which was significantly higher than the rate (43.8%, n = 28) of pathological acid reflux as detected by 24-hour esophageal pH monitoring (P = 0.002). Conclusions Salivary pepsin has an important significance for the diagnosis of GERD and GERD-related disorders. Salivary pepsin and 24-hour esophageal pH monitoring may complement with each other to improve the diagnostic efficiency.