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      • Research on the Influencing Factors and Transformation Path of Logistics Enterprise Low-Carbon Performance

        Jian Li(Jian Li),Seung-Lin Hong(Seung-Lin Hong) The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.1

        Purpose - This study expounds that logistics enterprises should make use of an information-sharing mechanism, benefit distribution mechanism, and government guarantee mechanism to optimize and balance resource allocation with cooperative participants. Design/Methodology/Approach - This study developed a theoretical research model with interface management analysis, interface resource allocation, and interface management measures as independent variables; an interface connection mechanism and collaborative innovation capability as intermediary variables; and the low-carbon performance of enterprises as a dependent variable based on the structural equation model (SEM) and the empirical test, by selecting a certain number of logistics enterprises nationwide as research objects. Findings - This study discloses that elements such as interface management analysis, interface resource allocation, interface management measures, interface connection mechanism, and collaborative innovation capability contribute proportionally to the low-carbon performance of logistics enterprises. Meanwhile, the interface connection mechanism plays an intermediary role in the impact of interface management analysis and interface management measures on the low-carbon performance of enterprises. Research Implications - This study proposes that the collaborative innovation capability of enterprises should be improved through various interface management measures, and that R&D and the application of low-carbon technology and equipment must be accelerated, thus promoting the improvement of the low-carbon performance of enterprises, and enabling a low-carbon transformation in logistics enterprises, and even the whole logistics industry, so as to help achieve the carbon peak and move toward carbon neutrality as soon as possible.

      • SCIESCOPUSKCI등재
      • KCI등재

        A Two-dimensional Supramolecular Network Built through Unique π-π Stacking: Synthesis and Characterization of [Cu(phen)2(μ-IDA)Cu(phen)·(NO3)](NO3)·4(H2O)

        Jian-Guo Lin,Ling Qiu,Yan-Yan Xu 대한화학회 2009 Bulletin of the Korean Chemical Society Vol.30 No.5

        A novel supramolecular network containing binuclear copper unit [Cu(phen)2(μ-IDA)Cu(phen)·(NO3)](NO3)· 4(H2O) (1) was synthesized through the self-assembly of iminodiacetic acid (H2IDA) and 1,10-phenanthroline (phen) in the condition of pH = 6. It has been characterized by the infrared (IR) spectroscopy, elemental analysis, single crystal X-ray diffraction, and thermogravimetric analysis (TGA). 1 shows a 2-D supramolecular structure assembled through strong and unique π-π packing interactions. Density functional theory (DFT) calculations show that theoretical optimized structures can well reproduce the experimental structure. The TGA and powder X-ray diffraction (PXRD) curves indicate that the complex 1 can maintain the structural integrity even at the loss of free water molecules. The magnetic property is also reported in this paper

      • KCI등재

        A facile technique to prepare cross-linked enzyme aggregates of bovine pancreatic lipase using bovine serum albumin as an additive

        Jian Dong Cui,Rong Lin Liu,Lin Bo Li 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.2

        Cross-linked enzyme aggregates from bovine pancreatic lipase were prepared by co-aggregation of lipase and BSA (Lipase-BSA-CLEAs). The main factors in the preparation of lipase-BSA-CLEAs were optimized. The highest activity recovery was around 75% under the condition of using 1% (v/v) glutaraldehyde as cross-linker and 0.05 g/L bovine serum albumin as feeder for 2 h cross linking. The optimum temperature for both lipase-CLEAs and lipase- BSA-CLEAs was measured as 60 oC, which is 10 oC higher than that of free lipase. Moreover, the lipase-BSA-CLEAs evidenced higher thermal stability and excellent reusability in comparison with the lipase-CLEAs. Lipase-BSA-CLEAs retained more than 75% of the initial activity after eight cycles of reuse, while lipase-CLEAs only retained 20% of its initial activity. Additionally, lipase-BSA-CLEAs showed more storage stability than free lipase and lipase-CLEAs. The high stability and recyclability of lipase-BSA-CLEAs make it efficient for different industrial applications.

      • KCI등재
      • Scutellaria Extract Decreases the Proportion of Side Population Cells in a Myeloma Cell Line by Down-regulating the Expression of ABCG2 Protein

        Lin, Mei-Gui,Liu, Li-Ping,Li, Chen-Yin,Zhang, Meng,Chen, Yuling,Qin, Jian,Gu, Yue-Yu,Li, Zhi,Wu, Xin-Lin,Mo, Sui-Lin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

        Background and Aims: Scutellaria is one of the most popular traditional Chinese herbal remedies against various human diseases, including cancer. In this study, we examined the active effects of Scutellaria extract and its main flavonoid constituents on the proportion of side population cells within human multiple myeloma cell line RPMI8226 in vitro and explored the potential molecular mechanisms involved. Materials and Methods: The contents of flavonoids in ethanolic extract of Scutellaria baicalensis Georgi were determined using high performance liquid chromatography. The antiproliferative effect of the ethanolic extract on RPMI-8226 was determined by CCK assay. Apoptosis was measured by annexin combining with propidium iodide in a flow cytometer. Cell cycle analysis was performed by propidium iodide staining in combination with flow cytometry analysis. Hoechst 33342 exclusion assay was used for the identification of side population within RPMI8226 cells. The expression of ABCG2 protein was assessed by Western blotting assay. Results: The content of major flavonoids constitutents of Scutellaria extract was baicalin (10.2%), wogonoside (2.50%), baicalein (2.29%), and wogonin (0.99%), respectively. The crude Scutellaria extract did not show significant anti-proliferative effect, apoptosis induction and cell cycle arrest in RPMI-8226 within the concentrations of $1-75{\mu}g/mL$. However, the ethanolic extract, baicalein, wogonin and baicalin reduced the side population cells in RPMI-8226, and data showed that baicalein and wogonin had stronger inhibitory effects. Correspondingly, they also exhibited significant effects on decreasing the expression level of ABCG2 protein in RPMI-8226 in vitro. Conclusions: Our results for the first time demonstrated a novel mechanism of action for Scutellaria extract and its main active flavonoids, namely targeting SP cells by modulating the expression of ABCG2 protein. This study provides an insight for new therapeutic strategies targeting cancer stem cells of multiple myeloma.

      • KCI등재

        Evaluation of the Stability of Aspirin in Solid State by the Programmed Humidifying and Non-isothermal Experiments

        Lin-Li Li,Xian-Cheng Zhan,Jian-Lin Tao 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.3

        The influence of both moisture and heat on the stability of aspirin was investigated by a single pair of experiments, one with programmed humidity control and the other non-isothermal, rather than many standard isothermal studies, each at constant relative humidity. In experiments, we adopted the acid-base back titration method to measure the content of aspirin in the presence of its degradation products. It was found that the degradation of aspirin could be expressed as ln[(c0-c)/c]=kt+D, where D was a lag time item not related to humidity and temperature. The relationship between the degradation rate constant k and humidity Hr and temperature T could be described as Arrhenius equation multiplied by an exponential item of relative humidity: k = A · exp(mHr) · exp(-(Ea/RT)), where A, Ea and m were the pre-exponential factor, observed activation energy, and a parameter related to humidity, respectively. The results obtained from the programmed humidifying and non-isothermal experiments, A=(1.09±2.04)×1012 h-1, Ea=(93.5±2.2) kJ ·mol-1 and m=1.18±0.19, were comparable to those from isothermal studies at constant humidity, A=(1.71±0.35)×1012 h-1, Ea=(94.9±0.7) kJ ·mol-1 and m=1.20±0.02. Since the programmed humidifying and non-isothermal experiments save time, labor and materials, it is suggested that the new experimental method can be used to investigate the stability of drugs unstable to both moisture and heat, instead of many classical isothermal experiments at constant humidity.

      • KCI등재

        중국인 한국어 학습자의 ‘체언+용언’ 형 연어 오류 양상에 대한 연구

        Jian-Dong Lin,김은호 한국현대언어학회 2019 언어연구 Vol.34 No.4

        Systematic and in-depth analyses of Chinese Korean language learners' lexical errors in general and of collocation errors in particular are relatively rare. This study presents empirical data verifying the informal observations and theoretic assertions that Chinese learners of Korean language produce 'unnatural' word combinations. In this paper the authors used a more comprehensive error taxonomy based on previous studies to analyse Chinese learners’ use of Korean collocations. The analysis revealed that the identified sources of errors were mainly from L2 intrinsic difficulty rather than the first language (L1) transfer. The findings from the Chinese learners’ errors in the use of Korean collocations have implications for L2 vocabulary teaching and learning, which should be of interest to wider Korean as a Second Language (KSL)/Korean as a Foreign Language (KFL) contexts. Systematic and in-depth analyses of Chinese Korean language learners' lexical errors in general and of collocation errors in particular are relatively rare. This study presents empirical data verifying the theoretic assertions that Chinese learners of Korean language produce 'unnatural' word combinations. In this paper the authors used a more comprehensive error taxonomy based on previous studies to analyse Chinese learners’ use of Korean collocations. The analysis revealed that the identified sources of errors were mainly from L2 intrinsic difficulty rather than the first language (L1) transfer. The findings from the Chinese learners’ errors in the use of Korean collocations have implications for L2 vocabulary teaching and learning, which should be of interest to wider Korean as a Second Language (KSL)/Korean as a Foreign Language (KFL) contexts.

      • KCI등재

        Evaluation of Galactomannan Enzyme Immunoassay and Quantitative Real-Time PCR for the Diagnosis of Invasive Pulmonary Aspergillosis in a Rat Model

        ( Jian Cong Lin ),( Yan Li Xing ),( Wen Ming Xu ),( Ming Li ),( Pang Bo ),( Yuan Yuan Niu ),( Chang Ran Zhang ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.8

        Since there is no consensus about the most reliable assays to detect invasive aspergillosis from samples obtained by minimally invasive or noninvasive methods, we compared the efficacy of an enzyme-linked immunosorbent assay (ELISA) for galactomannan (GM) detection and quantitative real-time PCR assay (qRT-PCR) for the diagnosis of invasive pulmonary aspergillosis. Neutropenic, male Sprague-Dawley rats (specific pathogen free; 8 weeks old; weight, 200 ± 20 g) were immunosuppressed with cyclophosphamide and infected with Aspergillus fumigatus intratracheally. Tissue and whole blood samples were harvested on days 1, 3, 5, and 7 post-infection and examined with GM ELISA and qRT-PCR. The A. fumigatus DNA detection sequence was detected in the following number of samples from 12 immunosuppressed, infected rats examined on the scheduled days: day 1 (0/12), day 3 (0/12), day 5 (6/12), and day 7 (8/12) post-infection. The sensitivity and specificity of the qRT-PCR assay was 29.2% and 100%, respectively. Receiver operating characteristic curve (ROC) analysis indicated a Ct (cycle threshold) cut-off value of 15.35, and the area under the curve (AUC) was 0.627. The GM assay detected antigen in sera obtained on day 1 (5/12), day 3 (9/12), day 5 (12/12), and day 7 (12/12) post-infection, and thus had a sensitivity of 79.2% and a specificity of 100%. The ROC of the GM assay indicated that the optimal Ct cut-off value was 1.40 (AUC, 0.919). The GM assay was more sensitive than the qRT-PCR assay in diagnosing invasive pulmonary aspergillosis in rats.

      • KCI등재

        Effect of key stratum on the mining abutment pressure of a coal seam

        Jian-Lin Xie,Jia-Lin Xu 한국지질과학협의회 2017 Geosciences Journal Vol.21 No.2

        This study investigates the effect of key stratum on the mining abutment pressure of a coal seam. Firstly, a total of 42 configurations with different key stratum thicknesses and heights have been numerically simulated by the Universal Distinct Element Code (UDEC) software. Then, through the analysis of two sets of parameters derived from the simulation results, the peak abutment pressure and the range of influence, shows that the effect of key stratum on the abutment pressure is conditional. For a relatively small key stratum thickness, less than 159 m, the effect on the abutment pressure is negligible unless the key stratum height is higher than the critical height of 421 m. On the other hand, for the key stratum thickness bigger than 159 m, the abutment pressure is affected irrespective of the key stratum height. Finally, in order to verify the simulation results, the abutment pressure of a field model has been analyzed. The analysis shows that the abutment pressure of the field model with a key stratum is 42% higher than that of the model without any key stratum. The stress at the field model has increased from the virgin stress of 14.6 MPa to the stress of 21.5 MPa. Meanwhile, the stress concentration coefficient has changed from 1 to 1.5, which caused the coal and gas burst disaster. The results of this study can be very useful to explain the reason for the occurrence of some dynamic disasters affected by the key stratum.

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