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      • 서포기 외가와 친가의 배경과 교육의 영향을 찾아서 -서포 양가의 배경과 윤씨 교육의 영향을 중심으로-

        윤경수 ( Kyung Soo Yoon ) 한국청소년효문화학회 2015 韓國의 靑少年文化 Vol.26 No.-

        Scopo(西浦) are built to Guwurunong(九雲夢) with filial to the mother up. Another Scopo was discovered works of Yoon(尹氏) built the Hacngjang(行狀) the aces of the mother. Sukjong(肅宗) is built and the Sassinamjeonggi(謝氏南征記) regrets that the relationship between Huibin(禧嬪) Two novels can``ve figured out that the splcndor of Yoon seen as the expression of piety. r ilial of Scopo has been referred to as the utmost filial piety arc the maternal and later, under the influence of the parents`` house. However, piety of Scopo is committed to Guwunmong and the Sassinamjeonggi under the influence of filial mother Yoon. Therefore, the fi lial piety of Scopo believing that wc preside way ID become a writer planted on literature, the womb and the regression of the three Confucian and Buddhist rituals and the collective unconscious, with Gojoseon(古朝鮮), Dangun(檀君), Hwanin(桓因), Hwanung(桓雄)``s bujajahyo(父慈子孝)and UngnYco(熊女), Dangun``s mojajahyo(母慈子孝) is contained in these two novels have the new meaning.

      • KCI등재

        Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

        KyungYoon Jeon,Eun‑Ji Ko,Young Lim Oh,Hongbae Kim,Wan Kyu Eo,김아리,Han Gyu Sun,Meesun Ock,Ki Hyung Kim,Hee‑Jae Cha 한국유전학회 2020 Genes & Genomics Vol.42 No.10

        Background Human endogenous retroviruses (HERVs) constitute around 8% of the human genome and have important roles in human health and disease, including cancers. Previous studies showed that HERV envelope (Env) proteins are highly expressed in cancer tissues and co-related with cancer progression. KAP1 has been reported to play a key role in regulating retrotransposons, including HERV-K, through epigenetic silencing. Objective The relationship between KAP-1 and HERV Envs expressions was analyzed only in tumor cell lines and has not yet been studied in cancer tissues. In this study, we analyzed the expression patterns and relationship between KAP1 and HERV Env proteins in ovarian cancer tissues. Method The expression patterns of KAP-1 and HERV Env proteins, including HERV-K and HERV-R, were analyzed in ovarian cancer tissue microarrays that contained 80 surgical specimens, including normal ovary and malignant ovarian cancers. Results The expression of HERV-R Env and KAP1 proteins is signifcantly higher in ovarian cancer compared with normal ovary tissues. However, the expression of HERV-K Env did not change signifcantly in cancer tissues. The expression patterns of HERV-K Env and HERV-R Env signifcantly increased in early stages of cancer and KAP1 expression was higher in certain stage and types of cancers. However, the expression of HERV-K Env, HERV-R Env, and KAP1 did not change in diferent age groups. The correlation between the expression of KAP1 and HERV-Env, including HERV-K and HERV-R, was not signifcantly correlated. Conclusions The results of this study showed that there was no signifcant correlation between the expression of KAP1 and HERV Env proteins in ovarian cancer tissues, unlike studies with cell lines in vitro. These results suggest that the actual expression of HERV Env proteins in ovarian cancer tissues may be regulated through various complex factors as well as KAP1.

      • 複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

        Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

      • KCI등재

        자연휴양림 이용자 요구사항 및 만족

        서경석 ( Kyung Seok Seo ),윤성훈 ( Sung Hun Yoon ),김갑열 ( Gab Youl Kim ) 한국감정평가학회 2011 감정평가학논집 Vol.10 No.2

        The research was studied about measure how each element affect to recreational forest visitors. And I can provide the useful information for the strategic decision-making to make value-up through characterization and differentiation of recreational forest. Those who use recreational forest were studied. Survey area was divided into five regions; Kyung-gi province, Kang-won province, Chung-chong province, Kyung-sang province and Jeon-ra province. And then national and local governments, individuals were classified as operating principals. Empirical analysis were analyzed by applying the Kano model. The questionnaire was analyzed by statistical methods; for data processing, along with a test of reliability in the measuring tools, frequency analysis. Human services and nature management components of recreational forest were classified as one-dimensional quality. Most users are more concerned about these elements. Recreational forest visitors are more concerned about quality associated with software components rather than hardware components. Recreational forest visitors with high interests and a high level of satisfaction about recreational forest has more concerned about the quality.

      • 치성 낭종의 임상-병리학적 소견과 TGF-α 및 TGF-β 발현

        한경민,김용환,박진혁,윤형기,윤혜경,김우형,이희철 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

        Objective : Periapical cyst is a relatively common disease but heterogenous in histogenesis, and inflammatory reaction and fibrosis of varying degree are associated in the cystic wall. The aim of thes study is to evaluate the clinico-pathologic characteristics such as patient's age, ses, location, and the degree of inflammatory reaction and fibrosis of periapical cyst and the role of TGF-α and TGF-β cytokines in the inflammed periapical cyst. Methods and Material : The materials were 43 cases of periapical cyst and clinical information with age, sex, location(maxilla vs mandible, right vs left, region involved) were recorded. Histopathological examination on the degree of inflammatory reaction and fibrosis and immunohistochemical stining for TGF-α and TGF-β were perfomed. Satistical analyses between clinical parameters, the degree of inflammation and fibrosis and expressions for TGF-α and TGF-β were followed. Results : 1. Thirt(69.8%) of 43 cases were older than 20 year-old. and no significant differences of incidence according to patient's sex was noted. In 25(58.1%) out of 43 case. 20(54.1%) out of 37 cases, and 20(48.8%) of 41cases, the cyst was located on the maxilla. in right side and in premolar region respectively. 2. The cysts of developmental and inflammatory origin were 24(55.8%) and 19(44.2%) of 43 cases, respectively and there were no siginificant differences of patient's age, sex, and location of cysts according to the origin of cysts. 3. Fibrosis was more conspicuous in cases older than 20 year-old. (p=0.0179), but no significant difference in the degree of inflammatory reaction according to patient's age and in the degree of inflammatory reaction and fibrosis according to sex and location of the cysts were seen. 4. Inflammatory reaction was slightly more in cysts of inflammatory origin, but no significant defferences in degree of inflammation and fibrosis according to origin of the cysts. 5. The degree of inflammatory reaction and TGF-α and TGF-β expressions showed a tendency of positive correlation(p=0.1563), but there were no statistically significant relationships between the degree of inflammation and fibrosis and TGF-α and TGF-β expressions. 6. In the cysts of developmental origin, TGF-α expression in the epithelial cells was significantly increased than inflammatory origin, but TGF-α and TGF-β expressions in the inflammatory cells and stromal cells showed no significant difference according to the origin Conclusion : The degree of inflammatory reaction and fibrosis of periapical cysts was different according to patient's age and location of the cyst. TGF-α and TGF-β cystokines seemed to be involved in the inflammatory reaction and fibrosis of periapical cyst, however, TGF-α and TGF-β expressions was not parallel to the degree of inflammatory reaction and fibrosis. These results suggest that other cytokines in addition to TGF-α and TGF-β may also be involved in the inflammatory reaction and fibrosis of periapical cyst. Increased TGF-expression in the epithelial cells of the cysts of developmental origin could be a helpful finding to defferentiate the origin of the periapical cyst.

      • KCI등재

        『딕테』에 나타난 디아스포라의 언어 고찰

        윤향기(Yoon hyang-ki),이경영(Lee Kyung-young) 한국비평문학회 2008 批評文學 Vol.- No.29

        This paper is an analysis about Dictee written by Cha, Hak-Kyung, a Korean-American, who tried for works beyond genre focusing on matters of diaspora and language. Until he passed away at age of 31, he was a writer who solidly dealt with images, text relations, implication of women and bodies, and substance of diaspora by moving about most energetically in many sorts of medias such as books, films, videos, mail arcs, ad criticism, stamp arts, and performing arts. Dictee has some difference from existing books that we've seen so far. This book tells stories about shunned strangers, existence of minor races, experience of women, suffering as Japanese colony, longing of innocent love, and vivid self-awareness of himself, within a dispersed world that he starred from himself. She already expressed a multicultural ideal in which all the diversity can harmonize beyond the walls of races, religions, languages, and ideology. The root of multiculturalism is based on pluralism. In this paper, the author deeply scrutinized the non-existence and transcendence of time and space and their eternity. And he also accepted Cha Hak Kyung's mythological recognition as historical consciousness replaced by lives with wings and free flight. Kim, Kyum-Hyang expressed Dictee as voice of shaman or voice of The Princess Bari in Comparison Study of Mythologies Appeared in Dictee Written by Cha, Hak-Kyung and Comfort Woman Written by Nora Okja Keller. However, this paper places more weight on the image of 'Butterfly' of Chuang-tzu, that is, restoration or transcendence. In other words, it is seen that women independently in their own language of Diaspora speaks about women's identity, which is even further expanding to the voice that Koreans make toward the world. In particular, Dictee is an example that resurrects Diaspora's linguistic outsiders' view into even strong points. This paper analyses and talks about the identity of Diaspora on the work beyond genre or mixed one. Especially, this unusual success is due to author's excellence in artistic talent and study of diverse cultural theories. However, more originally speaking, this is just because the author was able to experience by himself his disruption and dismantlement through his unique antecedent and thus reform this into artistic works.

      • KCI등재

        저체중 또는 과체중 청소년에서 캠프 프로그램을 이용한 영양 교육효과에 관한 연구

        성미경,승정자,류화춘,박재년,박동연,최미경,조경옥,최선혜,이윤신,김유경,이은주 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

        This study was performed to evaluate the effectiveness of a nutrition education program developed for nutritionally imbalanced adolescents. A summer nutrition camp was held for 23 overweight and 16 underweight subjects. Its effectiveness with regard to was evaluated at the end of the camp and 6 months later. Nutrition knowledge, nutritional attitude, food behavior, nutrient intake, exercise habit and ideal body figures desired by the subjects. The results showed significantly higher nutrition knowledge scores at the end of the camp as compared to those obtained prior to the camp program, and these scores were maintained for at least six months. Nutrition attitude scores also improved after the education program, and these improved scores also lasted for 6 months. However, the food behavior scores measured 6 months after the education program were not significantly different from those obtained prior to the camp. Also, the exercise habit, the ideal body figures and the body figures desired by the subjects remained unchanged. When nutrient intakes of subjects were assessed before the program and 6 months later, the mean daily vitamin C intake was significantly increased after the education program. Also, the intake of iron from plant food sources increased in the overweight subjects, while less iron from animal source were consumed by the underweight subjects. Both groups tended to consume more vegetables and fruits 6 months after the education program which may have contribute to the higher vitamin C and plant-based iron intakes. These results indicate that a 4-day nutrition education camp program sustained changes in nutrition knowledge and nutrition attitude for 6 months. The increased intake of vegetables and fruits was also achieved through this education program. However, changes in dietary behavior in adolescents may require repeated education.

      • 레이저 가공에서 빔변수가 미치는 영향에 관한 연구

        강경구,방세윤,윤경구,황경현,이성국 동국대학교 산업기술연구원 1997 산업기술논문집 Vol.9 No.-

        레이저 가공시 조사되는 레이저 빔의 특성을 나타내는 변수 - 예를 들면, 빔의 형상, 초점면과 소재사이의 거리, 빔 강도 분포, 빔의 발산각, 실제 빔이 퍼져가는 양상이 이상적인 Gaussian 빔에 비해 얼마나 큰지를 나타내는 beam quality factor 등 - 이 가공결과에 큰 영향을 미치는 것은 경험적으로 잘 알려져 있다. 특히 원적외선 레이저로 천공, 에칭 또는 엑사이머 레이저로 ablation 가공을 수행할 때는 이러한 빔특성 변수의 영향이 극대화된다. 본 연구에서는 중요한 빔특성 변수의 영향을 가능한 독립시켜 정성적 및 정량적으로 파악하기 위해 연속발진 모드의 레이저빔 사용시 열전도에 의한 손실을 고려하였으며, 문제를 단순화해 빔 또는 가공소재의 상대적인 움직임이 없는 천공 (또는 에칭제거)의 경우에 대하여, 수치모사를 통해 여러 가지 빔 변수의 변화가 가공결과에 미치는 영향을 살펴보았다. 레이저 빔의 초점의 위치를 표면에서 멀리하면 가공깊이는 감소하게 되며, 같은 간격일 때는 소재의 내부에 위치시키는 것이 다소 유리하다. 또한 빔의 발산각이 작고, beam quality factor 값이 1에 가까울수록 깊은 가공을 얻을 수 있음을 파악하였다. In laser machining such as drilling with CO_2 or Nd:YAG laser, and etching or ablation with Excimer laser, one of the most important parameters affecting the machining results is known to be beam characteristics. In this paper a study is performed through a numerical simulation with the appropriate model to investigate the effects of beam parameters qualitatively and quantitatively, especially in the process of laser drilling of ceramics and ceramic composites. Results of different beam conditions reveal that the machined hole becomes deeper as (ⅰ) the beam divergence gets smaller,(ⅱ) beam quality factor approaches unity, and (ⅲ) beam focus lies nearer to the surface of the workpiece.

      • Jo,Kyung-Yul

        조경열,최윤수,석경순 대구효성가톨릭대학교 1986 연구논문집 Vol.32 No.1

        A new spectropotometric determination of citric acid was examined using carbonyldiimidazole (CDI) which has been used in petide synthesis. CDI was reacted with citric acid to form yellow acyl-imidazole derivative (λ??443nm) in dichloroethane. This colored reaction was so characteristic with tricarboxylic acid that can be used selective determination of citric acid in common carboxylic acid. As increasing the reaction temperature, the acyl compound was decomposed to produce the substance of which physical property was similar to the hydrolized compound. Citric acied was calibrated in the range of 1-6μg/ml and the extinction coefficient of the acyl-imidazole compound was 28000 in this condition.

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