유아 음악교육에 관한 一考

김복례,박경란 인제대학교 아동ㆍ가족복지연구소 1998 아동ㆍ가족복지연구 Vol.2 No.-

This study reviewed the relationship between the early childhood music education and child's development, and the early childhood music education in Korea. 1. The relationship between the music education and child development. 1) The music has significant effect on the emotional development of a child. 2) The music has an important influence on the language learning. 3) The music helps the cognitive development of a child. 4) The music is related to the social development of a child. 2. Early childhood music education in Korea. 1) The environment to enjoy music is poor : the facilities, equipment and teaching method for music education is not sufficient. Lack of qualified teacher is another problem. 2) Music education should focuses on the child so that the child's musical thinking can be respected and his talent appreciated. The content of the music education should be suitable to the child's level, meet child's interest and demand, and provide abundant musical experience. In this respect, the role of the music teacher is very important.

생균제(probiotics)의 이해와 작용기전

문경래 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

Probiotics are defined as nonpathogenic living micro-organisms, including some commensal bacterial flora, which have beneficial effects on host health and disease prevention and/or treatment. They have shown beneficial effects of probiotics on several human diseases, such as ntibiotic-associated diarrhea and acute infectious diarrhea, irritable bowel syndrome and atopic dermatitis in children. Most commonly employed probiotics were Lactobacillus GG, Bifidobacterium spp., Streptococcus spp., and the yeast Saccharomyces boulardii. Studies discussed in this review suggest 3 distinct cellular and molecular mechanisms for probiotic regulation : 1) Probiotics block pathogenic bacterial effects by producing bactericidal substances and competing with pathogens and toxins for adherence to the intestinal epithelium; 2) Probiotics regulate immune responses by enhancing the innate immunity and modulating pathogen-induced inflammation via toll-like receptor-regulated signaling pathways; and 3) Probiotics regulate intestinal epithelial homeostasis by promoting intestinal epithelial cell survival, enhancing barrier function, and stimulating protective responses. Significant adverse effects are rare, and there are no known interactions with medications.

Helicobacter pylori가 만성위염과 위종양에 미치는 영향에 관한 면역조직화학적 밑 초미세구조적 연구

문경래,정순봉,이미숙,이미자,서재홍,김만우,박찬국 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Helicobacter pylori (H. pylori) is accepted as a principal cause of chronic gastritis and an important factor in the pathogenesis of peptic ulcer and gastric malignancy. The aim of our studies is to investigate relationships between H. pylori and gastric epithelial cells. Materials ðods : One hundred and eighty one H. pylori positive cases of gastric biopsy specimens were studied immunohistochemically and ultrastructurally. Results : p53 positive staining exhibited foveolar epithelial hyperplasia in 1 out of 32 cases, regeneration in 2 out of 12 cases, incomplete intestinal metaplasia in 5 out of 41 cases, complete intestinal metaplasia in 3 out of 18 cases, chronic ulcer in 1 out of 9 cases, tubular adenoma in 2 out of 14 cases and intestinal type of adenocarcinoma in 16 out of 21 cases. Ultrastructurally, H. pylori was observed to be in direct contact with the microvilli of the target cells and was demolishing the surface microvilli. The organisms were in close contact with the uncoated cell membrance. Penetration into the gastric cells by a few organisms was associated with marked cell damage and ultimately to cell disintegration. Conclusion : Our results suggest that H. pylori plays a role in the pathogenesis of gastric cancer, leading a relatively slow, long lasting process that induces chronic active gastritis, intestinal metaplasia, dysplasia, and adenocarcinoma of intestinal type.

경구용 전해질 용액 치료의 최근진전

문경래 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

의학전문대학원의 교육과정 개발

문경래 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

유방암종에서 p53, cyclin D1 및 cathersin D 단백발현의 의의

문경래,김환정,이미자,기근홍,서재홍,양정원,조현진 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives: Breast carcinoma is a heterogenous disease. The prognosis of this carcinoma correlates with various prognostic factors. The aim of this study was to assess the prognostic significance of expression of p53, cyclin Dl and cathepsin D protiens in association with various prognostic factors in invasive breast carcinoma. Materials and Methods: The relationship is presented between expression of p53, cyclin D1 and cathepsin D by immunohistochemistry and various established prognostic factors such as tumor size, histologic grade, lymph node status and extensive intraductal component in 55 cases of invasive breast carcinoma. Results: No significant correlations were observed between expression of p53, cyclin Dl and cathepsin D and tumor size. The expression of p53 correlated with high histologic grade. The expression of p53 and cyclin Dl correlated with lymph node metastasis. Conclusion: These results indicate that expression of p53 and cyclin Dl in invasive ductal carcinoma may be an important prognostic factor, closely related to the high histologic grade and lymph node metastasis.

영·유아의 영양평가

문경래 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

Nutritional assessment therefore should be an integral part of the care in infant and and young child. Components of a complete nutritional assessment include a medical history, nutritional history including dietary intake, physical examination, anthropometrics (weight, length or stature, head circumference, midarm circumference, and triceps skinfold thickness), skeletal maturity staging, and biochemical tests of nutritional status. The use of age, gender, and disease-specific growth charts is essential in assessing nutritional status and monitoring nutrition interventions. The importance of accurate measurements using trained personnel and appropriate equipment cannot be overemphasized.

도시지역 초등학생에서 주의력결핍 과잉운동장애의 유병율

표경식,박상학,김상훈,조용래,김학렬,문경래 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : To study the prevalence of ADHD in urban elementary school children using the Korean version of the disruptive behavior disorders parent rating scale. Materials and methods : 6,372 students from seven urban elementary schools were targeted using the parent rating scale. Results : (1)The total ADHD prevalence was 6.1%. It can be broken down as follows: 4.1% was the Inattentive type, 1.0% was the Hyperactive-impulsive type and 1.1% was the Combined type. 8.3% occurred in male students and 3.9% occurred in female students. The prevalence in boys was significantly higher. (2) The prevalence of Conduct Disorder(CD) was 0.3%: 0.2% for male students and 0.3% for female students. There was no significant difference between girls and boys. (3) The prevalence of Oppositional Defiant Disorder(ODD) was 4.4%: 5.0% for boys and 3.9% for girls. The value for boys was significantly higher. (4) A statistically significant difference between grades was found with ADHD, but no significant difference between grades was found with CD and ODD. (5) In the results of the comorbidity research, ADHD accompanied by CD was 2.3%. ADHD accompanied by ODD was 25.5%. ADHD accompanied by both CD and ODD was 4.1%. (6) Mild forms of ADHD, CD and ODD were found four times more often than that observed in typical cases. Conclusion : Prevalence of ADHD in urban elementary schools is high and CD or ODD is accompanied more frequently. In the future, the school mental health project should be focused mainly on ADHD. From the beginning of urban elementary schools, ADHD should be screened for. Intervention is required depending on whether or not there are accompanying diseases.

모유 은행의 최신개념

문경래 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

베체트병에서 비스테로이드성 소염진통제에 의해 발생한 대량 소장출혈 1예

강인숙,류연주,장지은,정성애,이지수,조영주,이경은,이지희 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

Bechet's disease(BD) is a chronic inflammatoroy condition involving several organs inclu-ding gastrointestinal tract. Gastrointestinal tracts involvement in BD has been identified throughout the entire alimentary tract and commonly accompanies ulcerative lesions in the small and large bowel. It is debatable whether BD could be included among seronegative spondyloarthropathy (SPA).SPA usually occurs without overt sign of intestinal inflammation, but significant number of patients have asymptomatic intestinal inflammation, usually affecting ileum. Since most patients with SPA in-cluding BD are treated with NSAIDS. However, NSAID may play a role in aggravation or provo-cation of intestinal inflammation. Special attention to asymptomatic intestinal inflammation is needed, especially when NSAIDs are used for management of arthritic symptom in SpA. We experienced a case of BD which was complicated by a massive small bowel bleeding precipitated by NSAID use. 저자들은 베체트병 환자에서 비스테로이드성 소염진통제 사용 후 발생한 대량 소장 출혈의 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.