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외상후 뇌척수액 이루를 동반한 재발성 세균성 뇌막염 1례
박래성,황성수,한지환,이경일,임용선 대한감염학회 1994 감염 Vol.26 No.3
저자들은 교통사고로 기저 두개골 골절과 좌측 측두골 골절, 좌측 외이도 파열상을 받은 후, 외상성 뇌척수액 이루를 동반한 재발성 세균성 뇌막염으로 4차례 입원한 환아에서 측두골 CT을 사용하여 측두골 골절과 RI cisternography를 사용하여 뇌척수액 누출을 확인하고, 단순 유양절개술을 시행하여 유돌개의 골피열과 경막 결손을 발견하였고 그 사이로 뇌척수액 누출을 확인하였으며, 경막 복원술로 치료한 환아 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. A 9-year-old male with repeated(four times in 2 years) pneumococcal meningitis after head trauma by traffic accident is reported. RI cisternography demonstrated an abnormal accumulation of radioisotope in the left ear cavity, suggesting concealed CSF fistulae (otorrehea). The origin of CSF fistulae (bony dehiscence of tegmen mastoideum and dural laceration) had been detected by simple mastoidotomy. The dura defect was successfully repaired with the initial operation used by perichondrium and temporal fascia. In order to prevent disastrous complications of repeated purulent meningitis, a detailed study to disclose CSF fistulae should be done in cases of posttraumatic meningitis.
12주 간의 규칙적인 운동이 심부전증 환자의 심폐 기능에 미치는 영향
이한준(Han Jun Lee),서한교(Han Kyo Seo),전태원(Tae Won Jun),김경래(Kyeong Lae Kim),박익렬(Ik Ryeul Park),이광희(Kwang Hee Lee),박성태(Sung Tae Park),김기정(Ki Jeong Kim),서동일(Dong Il Seo),박은경(Eun Kyung Park) 한국사회체육학회 2007 한국사회체육학회지 Vol.0 No.31
The purpose of this study is to examine the effects of regular exercise on cardiopulmonary function in patients with CHF during 12 weeks. 30 patients with CHF (EF<40) participated in this study. The subjects were randomly assigned to three groups; supervised exercise group(N=10), home-based exercise group(N=10), control group(N=10). Exercise testing by cycle ergometry was used as 10W ramp protocol. VO2peak, HRrest, HRpeak, BP, exercise tolerance and half time were analyzed. Exercise intensity was 60%HRR or 60%VO2R. The results of the study can be summarized as follows:1. There was significant difference of VO2peak among three groups. SG and HG wsignificant increased than control group(p<.05). 2. HRrest was decreased significantly after exercise in HG(p<.05). 3. HRpeak was not significant difference among three groups, but significant decreased after exercise in SG(p<.05). 4. SBPrest was no significant difference among three groups. But SG and HG were significant decreased than control group(p<.05). 5. DBPrest was no significant difference among three groups, but significant decreased after exercise in HG(p<.05). 6. Exercise tolerance(duration) was significant increased after exercise in SG and HG(p<.05). But control group was significant decreased after exercise(p<.05). 7. Half time was significant decrease after exercise in both exercise groups(p<.05).
김한나 ( Han Na Kim ),정경아 ( Kyung Ah Jeong ),정혜원 ( Hye Won Chung ),배근량 ( Geun Ryang Bae ),한복기 ( Bok Ghee Han ),김형래 ( Hyung Lae Kim ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.12
목적: 본 연구는 가임기 여성에서 다낭난소증후군으로 인한 사회경제적 손실에 대한 비용을 진단 기준과 유병률 또는 발생률자료를 이용하여 추정하고자 시행되었다. 연구 방법: 한국에 거주하는 가임기 여성 8,588명을 대상으로 이화여자대학교 목동병원에서 설문조사와 검진을 실시하여 다낭난소증후군을 조사하였다. NIH 기준에 따라 진단된 다낭난소증후군의 유병률은 가임기 여성 (국내 약 1,100만명 추계)의 10.4%로 나타났다. 가임기 동안의 다낭난소증후군 확진을 위한 검사비를 계산하였으며, 다낭난소증후군과 연관된 질병의 유병률과 치료에 소요되는 비용을 추정하여, 다낭난소증후군으로 인한 국내 총 사회경제적 손실비용을 산출하였다. 결과: 다낭난소증후군의 1년간 진단 및 치료비용으로 드는 직접비는 1인당 약 147만원, 가임기 다낭난소여성에서 총 소요되는 연간 비용은 3,100억원이 소요되는 것으로 추정된다. 연간 작업손실비용은 연간 일인당 315만원, 가임기 다낭난소여성에서 총 연간 작업손실비용은 700억원 가량이다. 이를 합산한 다낭난소증후군으로 인한 사회·경제적 비용은 총 약 3,800억원으로 추정되었다. 결론: 다낭난소증후군의 진단을 위한 초기 검사비용은, 이후에 발생할 수 있는 전체 사회경제적 소요비용에서 매우 부분적이므로 조기진단을 확대하여 조기치료를 함으로써 합병증 을 막는 방법이 비용 대비 효과적이다. Objective: The objective of the study was to estimate socioeconomic burden of polycystic ovary syndrome (PCOS) during the reproductive life span using current definitions and prevalence or incidence data. Methods: Questionnaires were given to 8,588 reproductive women reviewed at Ewha Womans University Mokdong hospital. The PCOS affected approximately 10.4% of reproductive-aged women (11 million women in Korea, prevalence rate according to 1990 National Institutes of Health PCOS diagnosis criteria). We tied general societal cost data for the different health consequences to reproductive-age PCOS costs, using prevalence data. Results: We estimated the mean annual cost of the initial evaluation to be ₩76 hundred million, that of hormonally treating menstrual dysfunction, providing infertility care, diagnosis/treatment of endometrial hyperplasia, GDM, type 2 DM, and hypertension to be ₩280 billion. The total annual socioeconomic cost of evaluating and providing care to reproductive-aged PCOS women in Korea is ₩350 billion. Conclusion: Because the cost of the diagnostic evaluation accounted for a relatively minor part of the total socioeconomic costs, more widespread screening for PCOS appears be a cost-effective strategy, leading to earlier diagnosis and intervention and possibly the amelioration and prevention of serious sequelae.
치환 페나실 벤젠 슬포네이트와 N, N-디메틸 아닐린 사이의 속도론적 연구
홍성완,한광래,이준경 又石大學校 1990 論文集 Vol.12 No.-
Kinetic studies of nucleophilic substitution reactions of phenacyl. benzeneslfonates(PBS) with N, N-dimethyl anilines(DMA) were conducted by conductometric method. Hammett and Broensted values were determined, in order to examine the transition state variations caused by changes in nucleophiles, substituents and indicated a relatively advanced bond-formation in the transition state. Application of potential energy surface(PES) and quantum mechanical(QM) models of transition state characterization lead us to conclude that the reaction proceeds via associative S_N2 mechanism. It was found that reactivity-selectivity principle(RSP) and Bell-Evans principle(BEP) held within the DMA series and hence constituted a good example of a thermodynamically controlled reaction series but are violated between two different reaction series with DMA and aniline.
Choi, Taesoo,Yoo, Koo Han,Choi, Seung-Kwon,Kim, Dong Soo,Lee, Dong-Gi,Min, Gyeong Eun,Jeon, Seung Hyun,Lee, Hyung-Lae,Jeong, In-Kyung The Korean Urological Association 2015 Korean Journal of Urology Vol.56 No.6
<P><B>Purpose</B></P><P>The aim of our study was to evaluate the association of several factors with spontaneous stone expulsion, including ureteral stone characteristics (size, location, hydronephrosis, perinephric stranding), types of medications prescribed (α-blocker, low-dose steroid), and other possible demographic and health-history factors (gender, age, serum creatinine, underlying diabetes mellitus [DM], and hypertension).</P><P><B>Materials and Methods</B></P><P>A total of 366 patients with ureteral stones were enrolled. All patients underwent watchful waiting without any invasive procedures. Initial diagnoses of ureteral stones were confirmed by computed tomography scans, which were taken at approximately 1-month intervals to check for stone expulsion. Univariate and multivariate analyses were conducted to identify significant factors that contributed to stone expulsion.</P><P><B>Results</B></P><P>Among 366 patients, 335 patients (91.5%) experienced spontaneous stone passage during a mean follow-up period of 2.95±2.62 weeks. The patients were divided into two groups depending on the success of spontaneous stone passage. Univariate analyses revealed that stone location (p=0.003), stone size (p=0.021), and underlying DM (p<0.001) were significant predictors of stone passage. Multivariate analyses confirmed that stone size (p=0.010), stone location (p=0.008), and underlying DM (p=0.003) were independent predictive factors affecting stone passage.</P><P><B>Conclusions</B></P><P>Stone size, location, and underlying DM were confirmed to be significant predictive factors for spontaneous passage of ureteral stones. Urologists should consider active procedures, such as shock wave lithotripsy or ureteroscopy, rather than conservative management in patients presenting with proximally located stones, large ureteral stones, or underlying DM.</P>
김태호,이경미,이동호,송인성,박민정,김정룡,정중기,장미수,이진혁,이국래,신경한 대한소화기내시경학회 1998 Clinical Endoscopy Vol.18 No.6
Most submucosal tumors of the stomach are of mesenchymal origin. According to the advances of immunohistochemical staining and electron microscopy, spindle cell tumors which were considered as leiomyoma or leiomyosarcoma appeared to be heterogeneous group; from smooth muscle cell, neural, bidirectionally differentiated cells of smooth muscle cell and neural cell, or immature mesenchymal cell. Therefore, the gastrointestinal mesenchymal tumors are referred to as gastrointestinal stromal tumors. The biologic behavior of gastrointestinal stromal tumors is difficult to predict, except benign leiomyoma and schwannoma. Recently, we experienced a case of 5 cm-diameter submucosal tumor with a central ulcer on body of the stomach, endoscopically. The tumor was a well cir- cumscribed submucosal mass located in the midbody along greater curvature. Micros- copically, the tumor was composed of fasciculating bundles of spindle cells with benign nuclear atypia and peripheral lymphoid cell cuffing. The tumor cells revealed a diffuse strong immunoreactivity to S-100 protein and vimentin, but were negative to desmin and smooth muscle actin. Ultrastructurally, many tumor cells showed a number of thin elon-gated and interdigitating dendritic-like cell processes, distinct uniform basal laminae, frequent cellular attachments and microfilaments. The findings supported the schwannian nature of the tumor.
Analysis of Diflubenzuron in Agricultural Commodities by Multiresidue Method
Sun-hee Park,Chang-ho Han,Ae-kyung Kim,Jae-min Shin,Jae-kyoo Lee,Young-hae Park,Ji-min Kim,Lae-hong Hwang,Min-su Chang,Mi-ok Song,Ju-sung Park,Eun-sun Yun,Mu-sang Kim,Kweon Jung 한국농약과학회 2014 한국농약과학회 학술발표대회 논문집 Vol.2014 No.10