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      • 고지방식이가 운동시 흰쥐의 글리코겐 이용에 미치는 영향

        민경선,장응찬,김형렬,민진아,신덕수 慶山大學校 2000 論文集 Vol.18 No.1

        Carbohydrate and fat ingestion during exercise are essential nutrient, but a number of opinion is different from their contents of food. In this point of view, to study how high-fat dietary contents affects glycogen utilization, 48 female Sprague-Dawley rats were trained on the treadmill trained for 4wk with consuming two high-fat diet and one high-carbohydrate diet. All animals were fed 79%high-fat diet(n=16, 79F), 40% high-fat diet(n=16, 40F), 70% high-carbohydrate diet(n=16, 70C). After the final day of training, one-half of rats in each the three groups were run to exhaustion (E), whereas the remaining rats served as rested controls (R). All animals were trained on a motorized rodent treadmill. The animals ran for 30min/d at 28m/min(0% grade), analysis items were glycogen, body weight and %Fat were measured. All data were examined by means of one-way ANOVA and significance was set at the p<0.05. The Duncan method was used for a post hoc test. Body weight were similar among the 79F, 40F and 70C groups. %Fat was significantly greater in animals that consumed the 79F group than in those on the 70C group (P<0.05), even though similar body weight each other. Generally liver and muscle glycogen concentration had more in 79FR, on the other hand, had less in 79FE compared with the others. The mean overall glycogen utilization rate was depressed in muscle and liver after animals were on the 79% F diet. In summary, the present study has suggested that consumption of 79% F diet during endurance training can lead to an increase in exercise performance in female rats. Some of the consequences training on F diet are an increase in body fat deposition and slower utilization of glycogen during exercise. These data indicate that rats exposed to a high-fat diet are capable of prolonging exercise in spite of limited glycogen stores. This improved capacity for exercise appears to be partially the result of muscular adaptations to the diet, which apparently increase the ability to oxidize fat and concomitantly spare glycogen.

      • KCI등재

        연구 논문 : 전기화학적 마이크로머시닝 기술을 이용한 균일한 니오븀 표면 에칭 연구

        김경민 ( Kyung Min Kim ),유현석 ( Hyeon Seok Yoo ),박지영 ( Ji Young Park ),신소운 ( So Woon Shin ),최진섭 ( Jin Sub Choi ) 한국공업화학회 2014 공업화학 Vol.25 No.1

        본 연구에서는 micro-contact printing을 통하여 니오븀 호일 표면 위에 균일한 에칭 pits를 형성하였다. 균일한 보호층을 형성하고자 전해연마의 효과를 확인하였으며, 기존의 O2 플라즈마 공정 없이 손쉽게 균일한 에칭 pits를 형성시킬 수 있는 조건을 확인하였다. 메탄올 혼합 전해질을 사용하여 10 min 동안 에칭을 진행한 결과 니오븀 호일 표면 위에 지름과 간격이 각각 10 μm와 5 μm로 잘 정렬된 에칭 pits를 관찰하였다. We describe the preparation of highly-ordered etching pits on the Nb foil through a micromachining. The effects of electro-chemical polishing on the formation of uniformly-patterned protective epoxy layer was investigated. Unlike the previous proc-ess using O2 plasma, well-ordered etched pits were prepared without any dry processes. As a result, the Nb foil with the well-ordered pits of 10 μm × 5 μm could be obtained by electrochemical etching in methanolic electrolytes for 10 min.

      • KCI등재

        휴대형 자동, 수동형 및 탁상형 자동 각막곡률검사기로 측정한 각막곡률의 신뢰성

        이경민,박신혜,신선영,Kyung-Min Lee,Shin-Hae Park,Sun-Young Shin 대한안과학회 2010 대한안과학회지 Vol.51 No.3

        Purpose: To compare the keratometry measurements by the handheld Nikon Retinomax K-plus2, the on-table Canon RK-5 autokeratometer, and the manual Topcon OM-4 keratometer and to evaluate the degree of agreement among the three instruments. Methods: Adults (n=30) and children (n=40) presenting toa tertiary eye hospital clinic were examined by an optometrist. Topcon OM-4 keratometer, Nikon Retinomax and the on-table Canon RK-5 autokeratometer analyses were performed in order. The horizontal and vertical keratometry data were measured. The vector components of astigmatism, mean bias and agreement among the three types of measurements were evaluated. Results: There were no significant differences among the three keratometers in horizontal or vertical keratometry or in central corneal astigmatism in both the adult and child groups (p-value>0.05). The keratometers which were estimated with Retinomax K-plus2 were highly correlated with those by on-table RK-5 autokeratometer (min. 0.89, max. 0.97) and Topcon OM-4 keratometer (min. 0.67, max. 0.94) in the adult group, while in the child group, the three instruments showed slightly decreased correlation (min. 0.45, max. 0.97 on RK-5, min. 0.36, max. 0.92 on OM-4), especially in the left eyes. Conclusions: The handheld Retinomax K-plus2 provided comparable data to that of the conventional on-table Topcon and manual keratometers. This instrument will beuseful in the clinic to measure keratometry in children or immobilized patients who have difficulty sitting during the examination.

      • KCI등재

        클로르헥시딘이 초음파 치석제거기에 의해 발생된 에어로졸 내 세균 수에 미치는 영향

        손우경,신승윤,계승범,양승민,Son, Woo-Kyung,Shin, Seung-Yun,Kye, Seung-Beom,Yang, Seung-Min 대한치주과학회 2009 Journal of Periodontal & Implant Science Vol.39 No.3

        Purpose: The aerosol generated by ultrasonic scaler can contain bacteria or virus which can penetrate into body through respiratory systems of dentists, dental hygienist or patients. The aim of this study is to evaluate the effect of chlorhexidine digluconate as preoperative mouthrinse or lavage for ultrasonic scaler on the reduction of viable organisms in aerosol produced during periodontal treatment using ultrasonic scaler. Methods: 30 patients with moderate chronic periodontitis were included and divided into 3 groups: Control (no preoperative mouthrinse and tap water as lavage), CHG (preoperative mouthrinse with 0.1% chlorhexidine digluconate and tap water as lavage), CHL (no preoperative mouthrinse and 0.1% chlorhexidine digluconate as lavage). Each patient received scaling or subgingival curettage for 30 min. In CHG group, mouthrinse with chlorhexidine digluconate was performed for 1 min. before treatment. Before, during and after scaling or subgingival curettage, air sampling was performed for 7 min. each (1000 L/7 min.) with trypticase-soy agar plate. Agar plates were incubated in $37^{\circ}C$ aerobically. The numbers of colony-forming units (CFU) were counted and compared. Results: The numbers of CFUs of the samples obtained during treatment were $97{\pm}14.0$ in control, $73.1{\pm}14.9$ in CHG group and $44.5{\pm}9.0$ in CHL group. The difference among the 3 groups was determined to be statistically significant (one-way ANOVA with Bonferroni's correction, p-value: 0.0003). In contrast, the numbers of CFU of samples obtained before and after treatment were not significantly different among the groups. Conclusions: Chlorhexidine digluconate used as preoperative mouthrinse or lavage for ultrasonic scaler can reduce the microorganisms in aerosol produced during periodontal treatment using ultrasonic scaler. Less number of microorganisms were detected when chlorhexidine was used as lavage for ultrasonic scaler.

      • KCI등재

        느릅나무 뿌리껍질 성분의 유방염균에 대한 항균효과

        신성진,윤민호,권순경,최우영 충남대학교 농업과학연구소 1999 농업과학연구 Vol.26 No.1

        젖소 유방염 병원균에 대한 느릅나무 뿌리껍질(楡白皮)의 항균활성을 검토하기 위하여 용매분획별로 시험한 결과 일반적으로 chloroform 분획이 가장 효과적이었고 butanol 및 물분획의 활성은 낮았다. 유방염균을 Fleish extract broth에서 액체 배양할 경우에 chloroform 분획을 첨가하면 생육이 억제되었으며 특히 Staphylococcus aureus 및 Streptococcus sp. No. 12는 초기생육이 현저하게 저해되는 경향을 나타내었다. Hoechst 제약의 표준방법에 의한 MIC 시험에서도 유사한 결과를 얻었다. 또한 건조한 느릅나무의 뿌리껍질 100g을 물로 추출하여 겉보기 점도 77.5 cP, 최대흡수 파장 440㎚의 황갈색 수용성 점질물 4.500㎖를 회수할수 있었다. 이를 정제 건조한 무게는 32~35g이었으며, 탄수화물 함량이 61.0±1.0%, 단백질 8.0±0.2%로서 다당이 주성분이었다. 이상의 실험결과를 통해 유백피의 용매 추출분획물은 항균활성을 나타내는 성분으로, 그리고 수용성 점질물은 흡수성과 점성이 높은 다당류로서 염증 부위에 수렴작용을 나타내는 성분으로 결론지을 수 있었다. The methanolic extracts from the elm (Ulmus davidiana var japonica) root barks which have been known as an oriental medicine Eubackpie for the treatment of edema, ulcer and inflammation were examined for their bacteriocidal effects on mastitis pathogens of milk cows. The growth of the pathogenic bacteria such as Staphylococcus aureus and Streptococcus sp. No. 12 was markedly inhibited by the chloroform fraction among the extracts, and these antibacterial activities were also supported by MIC test. Water-soluble mucilage was obtained from the root barks with a yield of 36.8∼40.2% bf dry weight basis. This substance appeared to be a kind of polysaccharide with 61.0±1.0% carbohydrate content, and to have hygroscopic and astringent properties due to its high viscosity and water absorption.

      • KCI등재후보

        연령에 따른 환자의 병원음식 만족도

        신민자,서경화 동아시아식생활학회 2003 동아시아식생활학회지 Vol.13 No.6

        The purpose of this study was to analyze the patient's satisfaction on hospital foods according to their age. The subjects were selected among the patients treated in the Eulgi University hospital during May of 2003. Two hundred twenty one patients (110 men, 101 women) were surveyed through questionnaires in terms of satisfaction on hospital foods and the food preference. The data were statistically analysed using χ²-test and their correlation. Satisfaction on general taste(p<0.05) and variety of hospital foods (p<0.05) were significantly different according to age. However, saltiness and serving temperature of hospital foods were significantly different according to sex(p<0.05). The preference of cooking method for meat, fish, vegetable and the preferred kinds of Kimchi(p<0.05) and milk & milk products(p<0.05) were significantly different according to age.

      • KCI등재

        아동기 우울증의 평가

        신민섭,김민경 대한소아ㆍ청소년정신의학회 1994 소아청소년정신의학 Vol.5 No.1

        요 약 성인의 우울증과는 달리 아동기 우울증의 존재와 정의에 대해서는 많은 논란이 있어왔 다.DSM-III(1980)에 이르러서야 공식적인 병명으로 인정되었으나, 아직도 아동기 우울증은 다른 정신과적인 장애에 비해 진단 준거 자체가 명확하게 정의되어 있지 못할 뿐만 아니라 발달 단계에 따라 우울 증상은 다른 양상으로 표현되므로, 아동기 우울증의 정확한 진단을 위해서는 다양한 평가 방법을 사용하여 여러 사람들로부터 정보를 얻는 것이 매우 중요하 다. 따라서 본 연구에서는 자기보고형 질문지, 면접」 행동 평정 척도, 구조화된 검사, 투사 법 검사 등 주요 평가 방법들을 고찰해보았고, 앞으로 아동기 우울증 평가 방법에서 해결되 어야 할 신뢰도 및 타당도에 관한 몇가지 문제점들에 대해 논의하였다.

      • KCI등재

        반응성 애착장애 아동의 애착유형

        신의진,이순행,이경숙,전여숙,노경선,민성길 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.6

        This study aims at examining examine the quality of attachment in children with Reactive Attachment Disorder(RAD). The subjects of this study were 26 chidren with RAD and 22 normal children as control group. The diagnosis of RAD was made according to DSM-Ⅳ and ICD-10 criteria of reactive attachment disorder. Attachment of each children was classified by using the Strange Situation Procedure(SSP). The data was statistically processed through Fisher's exact test and t-test. The results were as follows : Among the RAD children, 61.5% were classified as disorganized(D) type, 26.9% as anxious-avoidant(A) type, 11.6% as anxious-avoidant(C) type. Among the normal children, 63.5% were classified as secure attachment(B) type, 18.3% as anxious-avoidant(A) type, 13.6% as anxious-avoidant(C) type, 4.5% as disorganized(D) type. And RAD children had sifnigicantly higher proportion of disorganized(D) type and lower proportion of secure(B) type than that normal children. The above results suggest that RAD children has serious problems in their attachment relationship and there must be some consideration on serious attachment problems to make diagnosis and intervention of RAD children.

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