ZnS:Mn/ZnS:TbF3 적층구조의 형광층을 이용한 TFEL 소자의 제작 및 그 특성

김영진,김기완,박경빈,김호운,배승춘,조기현 한국센서학회 1997 센서학회지 Vol.6 No.1

The thin-film eletroluminescent (TFEL) device having the stacked structure of ZnS:Mn/ZnS:TbF₃ has been fabricated. Insulate layers used (Pb,La)TiO₃ and SiO₂ thin films. The emission color was white. The TFEL device employing ZnS:Mn/ZnS:TbF₃(8000Å) stacked phosphor layers showed the threshold voltage of 78V_(rms). And the brightness of the TFEL device was 400 ㎼/㎠ at the applied voltage of 100V_(rms). The emission spectrum of TFEL device had a wavelength from 450nm to 620nm. The manufactured devices can be a practical use as a TFEL devices of red, green and blue by using the color filters.

췌장암에서 Cyclooxygenase - 2 발현의 역할

김은경,이용욱,이규택,최규완,박동일,백승운,이준행,이종균,고광철,이풍렬,이종철,김재준,김완선,공구 대한소화기학회 2001 대한소화기학회지 Vol.38 No.3

Background/Aims: Accumulating evidence suggests that the use of NSAID may reduce the incidence of colorectal cancer. The likely mechanisms of these effects by NSAID is cyclooxygenase-2 (COX-2)-related inhibition of tumor proliferation and induction of apoptosis. The aim of our study was to examine possible roles and clinical significance of COX-2 expression in pancreatic cancer. Methods: Seventy-two pancreatic adenocarcinoma tissue specimens were obtained from surgical resection. After the immunohistochemical staining of the specimens, we examined proliferation activity (assayed by Ki-67 expression), apoptosis (by TUNEL stain), and microvessel density (by CD34 expression). We also investigated the relationship between the immunohistochemical expression of COX-2 and various clinicopathological characteristics. Results: The COX-2 positive rate in pancreatic epithelial cells was 41.7%. Proliferation index (PI) was significant higher in COX-2 positive specimens comparing to negative specimen (p=0.015) and the increase in intensity of COX-2 expression correlated with increasing PI (p=0.036). Apoptotic index (AI) was significantly higher in positivee COX-2 expression than in negative expression (p=0.044), but there was no significant difference in AI/PI between the COX-2 positive and negative specimens (p=0.44). The expression of COX-2 protein did not correlate with microvessel density, sex, age, differentiation, tumor size, stage, metastasis or patients survival. Conclusions: The expression of COX-2 enzyme in pancreatic cancer contributes to tumor proliferation, but is not related to apoptosis, angiogenesis or clinical characteristics. Further study is needed to examine the clinical usefulness of NSAID and COX-2 selective inhibitors.

이소성 ACTH 의 분비에 의한 ACTH 증후군을 동반한 소세포폐암 1 예

김경희,조성태,유재명,우인숙,박명재,박영이,지제근 대한내과학회 1997 대한내과학회지 Vol.53 No.5

About 5% of patients with SCLC have the ectopic production of ACTH. Ectopic ACTH production of SCLC is suspected when patients of SCLC have unexplained metabolic alkalosis and hypokalemia. Most patients lack the classic feature of Cushing's syndrome. According to the recent report, they have poor prognosis, which median survival is less than 4 months and associated with a high rate of complication during chemotherapy. Also a case of paraneoplastic CRH production with SCLC can mimic the ectopic ACTH syndrome hut it can be distinguished by immunohistochemistry or direct measurement of serum CRH level. We report here a case of small cell lung cancer associated with Cushing's syndrome of ectopic ACTH production. That is immunohistochemically provened by staining with ACTH.

심장 이식 후에 발생한 침윤성 폐 Aspergillosis 2 예

김희정,박성훈,홍석근,현민수,고경환,윤재형,이수금,오미혜,김명아,박국양 대한내과학회 1997 대한내과학회지 Vol.53 No.2

Case 1: A 39-year-old man underwent orthotopic heart transplantation on November 1994 for dilated cardiomyopathy. His postoperative course was unevenful and medications included daily cyclosporin A, Immuran and prednisone. On December 13.1994, he developed cough and sore throat. Chest radiographs revealed multiple patch growing lesions. Sputum fungus culture revealed Aspergillus Fumigatus. The patient was treated with daily infusion of amphotericin B. He remains well without evidence of relapse of Aspergillus, Case 2: This 39-year-old man had undergone orthotopic heart transplantation on November 16 1994 for dilated cardiomyopathy. In December 7.1994. he developed recurrent syncope. Chest radiographs revealed fungus ball like lesion on right lung field. On open lung biopsy and wedge resection of the mass was performed. Aspergillosis and CMV infection was demonstrated in the biopsy specimen. The patient was treated with conventional amphotericin B therapy for over 7weeks and Ganciclovir for over 2weeks. At the end of therapy chest X-ray showed only small residual scar in the area of previous mass.

분류가 있는 2중동심원관 통로의 유동 및 열전달 해석

김호영,장경수 고려대학교 공학기술연구소 1987 고려대학교 생산기술연구소 생기연논문집 Vol.23 No.1

A theoretical investigation was carried out to predict the characteristics of momentum and heat transfer for the flow through the passage consisting two coaxial cylinders with uniform injection from porous inner cylinder. Non-similar solution and discrete element methods were used to generate the numerical solutions of momentum and energy equations. For the parametric study, various parameters including radius ratio, ratio of injection to inlet velocities and Reynolds number at inlet were examined to obtain the effect of those parameters on the transport processes. As the results of present study, the effect of injection on the transport process is dominated near the inlet region. The mixing of two fluids increases with larger injection velocity as well as smaller radius ratio.

성인에서 반복적인 위장관출혈로 발현한 공장 거대 중복성 낭종

김영호,이경수,이상수,문원,강태욱,최규완,박동일,도재혁,백승운,이풍렬,이종철,김재준,류민규 대한내과학회 2001 대한내과학회지 Vol.61 No.3

Duplication of the alimentary tract is an unusual congenital anomaly which may occur at any level, from the oral cavity to the rectum. Jejunal duplication cyst is quite rare and most of them are presented in infancy with the symptoms of abdominal mass, obstruction, hemorrhage and perforation. But some cases has not been diagnosed till adult if duplication cyst was too small enough to cause symptoms. We report a case of a 28-year-old woman who presented with recurrent gastrointestinal hemorrhage as a result of an ulceration without ectopic mucosa in jejunal duplication cyst and was successfully treated with surgery.(Korean J Med 61:264-269, 2001)

Dieulafoy 양 병변에 의한 십이지장게실 출혈 1 예

김상현,김경환,이동현,송철수,정노원,박상제,김은규,하홍성,나일환,황윤이,성은영,최익수,신영기 대한소화기내시경학회 2001 Clinical Endoscopy Vol.23 No.1

Duodenal diverticula are first reported by Chomel in 1710. Duodenal diverticula are relatively common in adults with a prevalence of 23% in SRCP. The most duodenal diverticulum is asymptomatic. Complications such as obstruction, cholangitis, blliary stones, ulceration, perforation and hemorrhage can occur in approximately 10%. However, relatively few cases of bleeding from a duodenal diverticulum have been reported. The cause of bleeding from a duodenal diverticulum is uncertain and various suspected etiologies were suggested, such as ectopic gastric mucosa, stasis-induced ulceration, erosion into major vessels, aortoenteric fistuias, intradiverticujar polyp, aspirin-induced erosion. We report a case of a bleeding duodenal diverticulum by a Dieulafoy-like lesion and suggest this 1esion as one of posslble causes of blee4ng in duodenal diverticulum.

영양물 정주시의 체내호르몬 반응에 관한 연구 : 위암환자에서 본 영양물 투여시의 insulin 및 HGH 반응 Insulin and growth hormone responses following oral or intravenous alimentation in patient with far advanced gastric cancer

이진오,성호경,고주환,유용운,이종원,김진용,이장규 대한핵의학회 1975 핵의학 분자영상 Vol.9 No.2

심히 진행된 위암 환자에서 경정맥 포도당 투여시의 insulin 및 성장 호르몬 반응을 관찰하고 경구 투여시와 비교 검토하였다. 다시 위암 환자에게 아미노산 용액을 투여하고 혈중 insulin 농도와 성장 호르몬 농도 및 혈당량을 경시적으로 측정하고 정상인에서의 결과와 비교하여 다음의 결과를 얻었다. 1) 위암 환자에게 포도당 용액을 경구 부하하면 혈중 포도당 농도의 상승은 감소되었다. 2) 위암 환자에게 포도당 용액을 경구투여하였더니 insulin 반응은 정상인에서보다 감소되어 경정맥투여시와 유사하였다. 3) 위암 환자에게 포도당 용액 또는 아미노산용액을 경정맥 투여하여 성장 호르몬 농도의 상승을 관찰하였다. 4) 위암 환자에게 아미노산 용액을 정맥내로 투여하면 정상인에서와 같이 경구투여시에 비하여 insulin 반응의 감소가 관찰되었다. 5) 위암 환자에게 포도당 경정맥 투여시의 insulin 반응이 경구 투여시와 유사한 점에 대하여 고찰하였으며 아미노산 경정맥 투여시에는 insulin 반응에 유의할 필요성을 지적하였다. Glucose tolerance, insulin and growth hormone responses following glucose for amino acids administration by means of parenteral or oral load were studied in patients with far advanced gastric cancer. Hormone responses following nutrients load showed in patients with gastric cancer were compared to those of healthy subjects. Results were as follows: 1) Blood sugar appearance following oral glucose administration was diminished in patients with far advanced gastric cancer. 2) The insulin responses of gastric cancer following oral glucose were also diminished as compared to that of normal subjects and were identical with parenteral route. 3) Parenteral administration of glucose or amino acids to patients with gastric cancer resulted in a increase of plasma growth hormone level. 4) Lower insulin response to amino acids was observed on parenteral administration in patient with gastric cancer as in healthy subjects. 5) Author discussed that the low insulin response after oral glucose administration showed in gastric cancer, and any additional insulin requirement arise when longer periods of parenteral amino acid administration are necessary, as in the patient with malnutritions. $quot;

성폭력 피해자/생존자로서의 근대 최고 여성작가 김명순

김경애 ( Kim Kyung-ai ) 한국여성사학회 2011 여성과 역사 Vol.- No.14

근대최초의 여성작가 김명순은 탕녀의 대표적인 표상으로 인식되고 있다. 그러나 김명순은 데이트강간과 조선지식인남성들과 언론이 가한 2차 성폭력의 피해자이다. 성폭력의 피해자가 오히려 비난받은 가부장적 사회문화 속에서 김명순은 어머니가 기생 출신의 소실이었다는 사실이 덧붙여져 성적으로 문란한 여성으로 비난의 대상이 되었다. 성폭력 피해자 김명순은 일반적인 피해자들과 마찬가지로 고통을 겪었다. 우울증과 히스테리, 자살시도,남성과의 성관계와 결혼기피, 성폭력자들에 대한 분노와 증오로 복수를 꿈꾸었다. 또한, 자신의 고통을 통해 여성이 남성으로부터 억압을 비판하고 해방을 꿈꾸지만 홀로 이를 성취할 수 없음에 좌절하였다. 그러나 김명순은 홀로 처절한 노력과 종교의 힘으로 성폭력자들을 용서하였고 생존자로 거듭났다. 그러나 김동인이 김명순을 모델로 했다는 「김연실전」을 연재하기 시작하자 조선사회에서 사라졌는데, 그 이후의 김명순의 삶은 앞으로 연구해야 할 과제로 남아있다. Kim Myoung Soon, one of earliest Korean modern women writers has been known as a symbol of femme fatal. However, Kim was a victim of `date rape` and secondary sexual violence imposed by male intellectuals and media of Chosun. Under patriarchal socio-cultural background where victims of sexual violences are blamed, the fact that Kim`s mother was an ex-gisaeng concubine was added to brand Kim as sexually promiscuous. Like any victim of violence, Kim suffered from aftereffect-depression, hysteria, series of suicidal attempts, fear of sexual relationship with men and marriage, and rage and hatred against the attackers. Kim criticized the oppression women suffer from men and dream of women`s liberation, only to be disheartened by awareness that she alone cannot achieve the goal. However, through wretched effort and the power of religious(catholic) prayers, she forgave the attackers and was reborn as a survivor. When Kim Dong-in started to publish a novel `a story of Kim YeonSil` in serials, which allegedly was taken from the life of Kim Myoung Soon, she disappeared from Chosun society. The remaining life story of Kim is to be researched.

이덕무(李德懋)의 김창협(金昌協)비평 수용 연구 -이규보(李奎報)에 대한 비평을 중심으로-

김경 ( Kim Kyung ) 민족어문학회 2016 어문논집 Vol.- No.78

본고는 李德懋의 비평형성에 있어서 金昌協과의 영향관계를 파악하고자 하는 것이다. 즉 이덕무가 어떤 경로로 김창협의 비평관을 접하게 되었고, 무엇 때문에 김창협을 적극적으로 수용하려 하였는가라는 의문을 구명한 것이다. 이를 위해 李奎報 漢詩에 대한 비평에 한정하여 김창협의 「雜識外篇」 25칙과이덕무의 「李春卿」을 비교분석하였다. 먼저 이덕무가 유독 農巖系 문인들 중 李縡의 문하생들과 교유양상을 보여주는 것은 처가의 영향이라 할 수 있다. 또한 이들 문하생 중 이덕무와 직접적인 교류를 보인 인물은 金鍾厚와 金用謙인데, 특히 김용겸은 이덕무가 김창협의 문풍을 수용하는 과정에 있어 가장 큰영향을 준 인물이었다. 다음으로는 이규보 한시에 대한 비평인 김창협의 「잡지외편」 25칙과 이덕무의 「이춘경」을 비교분석하였다. 이덕무가 김창협의 비평에서 주목한 점은 첫째는 치밀한 비평과 전대 비평에 대한 비판적 수용태도이고, 둘째는 창작 태도와 관련된 작가에게 요구되는 내적수양의 중시였다. 이덕무와 김창협은 주자학을 바탕으로 하면서도 문예영역에서 유연한 자세를 보인다는 측면에서 유사한 면모를 확인하였고, 이를 통해 이덕무의 이러한 비평태도가 김창협과 연계되어 있다는 점 역시 알 수 있었다. 하지만, 창작에 있어서 이덕무는 작가의 내적조건보다 창작태도를 우선시 하였는데, 이는 김창협의 비평을 재해석하려는 태도였다. 따라서 이덕무는 김창협 비평에 대해 모방이 아니라, 무엇보다 그의 비평태도와 학문적 자세에 주목하여 적극적인 수용 자세를 보였고 비평에서도 이에 상응하는 모습을 보인 것이다. This paper aims to grasp the influential relationship with Kim Changhyeop in a development of Lee Deokmu`s literary criticism. In other word, it investigates questions about how Lee Deokmu encounters Kim Changhyeop`s critical perspectives and why he tries to accept it actively. To this end, I verified in which way Lee Deokmu accepted for Kim Changhyeop`s literary criticism and comparatively analyzed Kim`s Number 25 of 「JapJiOePyeon」 and Lee`s 「LeeChunGyeong」. Firstly, Lee Deokmu had associated particularly with disciples of Lee Jae among the line of NongAm because of his wife`s family. This explains in which way Lee Deokmu accepted for Kim`s literary criticism. Among these disciples, Kim Jonghu and Kim Yonggyeom had interacted with Lee Deokmu directly. Especially Kim Yonggyeom had the greatest impact in a process of his reception for the literary spirit of Kim Changhyeop. Secondly, I comparatively analyzed Kim`s Number 25 of 「JapJiOePyeon」 and Lee`s 「LeeChunGyeong」. Lee Deokmu focuses on Kim Changhyeop`s literary criticism in two points. Lee concentrates on Kim`s precise literary criticism and his critical attitude of accepting the criticisms of previous generations. And Lee focuses on his attitude of writing and his emphasis on a inner cultivation. I confirmed that they were similar in their stances, which was flexible toward literature even though it was based on the neo-Confucianism. I also assured that Lee Deokmu`s such attitude toward criticism was closely linked to Kim Changhyeop. However, Lee Deokmu gave his priority to writer`s attitude of writing over his inner condition in creative writing. That is a reinterpretation to Kim Changhyeop` literary criticism. Consequently, it can be said that Lee Deokmu is not a mere imitator but an active accepter of Kim Changhyeop by focusing on his critical and academic attitudes.