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      • Estimating Total Factor Productivity and Its components - Evidence from Manufacturing Sector of Tamilnadu, India

        Kumar,T. Sampath,Pradeep V. 한국유통과학회 2019 KODISA ICBE (International Conference on Business Vol.2019 No.-

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        The study applied Data Envelopment Analysis (DEA) to estimate total factor productivity growth and to identify the sources of productivity growth in the manufacturing sector of Tamil Nadu. The study considered 12 major sectors and estimated productivity growth and the major sources of productivity growth during the period 1981-82 to 2007-08. The study found that the productivity growth in the industrial sector of Tamil Nadu at the aggregate level during the test period was almost nil. While it is the case at the aggregate level, there are mixed results at the sectoral level. During the pre-reform period, there was significantly higher productivity growth in almost all the sectors contributed mainly by the improvements in efficiency. On other hand, there was productivity deterioration in the post-reform period since almost all the sectors witnessed negative productivity growth despite a technical change in the post-reform period. The study based on the empirical findings suggests that there will be productivity growth only if any improvement in the technology is accompanied by the corresponding improvement in the efficiency with which the technology can be turned into productivity gains. A well developed and skilled labour force along with the improvements in the technological developments will lead to higher productivity growth in the manufacturing sector both at the aggregate and sectoral level.

      • KCI등재

        Rapid Multiplex PCR Assay for the Simultaneous Detection of the Brucella Genus, B. abortus, B. melitensis, and B. suis

        ( Kumar Sanjay ),( Urmil Tuteja ),( Kumari Sarika ),( Dhirendra Kumar Singh ),( Ashok Kumar ),( Om Kumar ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.1

        The routine identification and differentiation of Brucella species is a time-consuming and labor-intensive process, which frequently places personnel at risk of laboratory-acquired infection. Here, we describe the development of a rapid multiplex PCR assay for the confirmation of presumptive Brucella isolates. The assay was able to identify and differentiate major human pathogens, namely B. abortus, B. melitensis, and B. suis, in a single test of less than an hour and a half.

      • KCI등재

        Intraoperative refractory status epilepticus caused by propofol -a case report-

        Kumar Abhyuday,Kumar Amarjeet,Kumar Neeraj,Kumar Ajeet 대한마취통증의학회 2021 Korean Journal of Anesthesiology Vol.74 No.1

        Background: Status epilepticus, when continued despite the administration of two antiepileptic drugs, is called refractory status epilepticus (RSE). The seizure-like phenomenon due to propofol is widely reported in the literature. However, RSE caused by propofol is rare and is a diagnostic dilemma. Case: A 44-year-old male patient presented with RSE during the intraoperative period and was under general anesthesia on propofol infusion. The seizure was resistant to benzodiazepines and phenytoin. Thereafter, the seizure subsided after the discontinuation of propofol infusion, and the patient was shifted to fentanyl and dexmedetomidine infusion for the maintenance of anesthesia. The postoperative follow-up was uneventful. Conclusions: This article focuses on the management of intractable intraoperative seizure and highlights the need for the exploration of seizure characteristics caused by propofol.

      • p16 Expression as a Surrogate Marker for HPV Infection in Esophageal Squamous Cell Carcinoma can Predict Response to Neo-Adjuvant Chemotherapy

        Kumar, Rajeev,Ghosh, Sankar Kumar,Verma, Akalesh Kumar,Talukdar, Anuradha,Deka, Monoj Kumar,Wagh, Mira,Bahar, H.M. Iqbal,Tapkire, Ritesh,Chakraborty, Kali Pankaj,Kannan, R. Ravi Asian Pacific Organization for Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.16

        Background: Esophageal squamous cell carcinoma (ESCC) is a common cancer in the north east of India. The present study concerned the prevalence of human papilloma virus (HPV) in the ESCC in north eastern India and its impact on response to chemotherapy. Materials and Methods: p16 expression, a surrogate marker for HPV infection was assessed in 101 pre-treatment biopsies of locally advanced ESCC, reported from a comprehensive cancer centre in north east India, using immunohistochemistry. All patients received neo-adjuvant chemotherapy. Response was assessed clinically and histopathologically with attention to p16 expression. Results: p16 was expressed in 22% of ESCC (22 out of 101) and was more prevalent in patients who were more than 45 years of age (P=0.048). p16 positive tumors appeared more commonly in the upper 2/3 of the thoracic esophagus (18 in 22). Nine of the 22 (41%) p16 positive tumors achieved pathologic complete response following neo-adjuvant chemotherapy (P=0.008). There was a trend towards reduced mortality in this group (P=0.048). Some 9 of the 20 (45%) patients who achieved pathologic complete response were p16 positive. Conclusions: Expression of p16 in ESCC correlates with higher rate of pathologic complete remission in patients undergoing neo adjuvant chemotherapy and could be a predictive marker for response assessment.

      • KCI등재

        Interleukin-1B (IL-1B-31 and IL-1B-511) and interleukin-1 receptor antagonist (IL-1Ra) gene polymorphisms in primary immune thrombocytopenia

        Deependra Kumar Yadav,Anil Kumar Tripathi,Divya Gupta,Saurabh Shukla,Aloukick Kumar Singh,Ashutosh Kumar,Jyotsna Agarwal,K. N. Prasad 대한혈액학회 2017 Blood Research Vol.51 No.4

        Background: Immune thrombocytopenia (ITP) is an immune-mediated disease caused by autoanti-bodies against platelets membrane glycoproteins GPIIb/IIIa and GPIb/IX. The etiology of ITP remains unclear. This study evaluated the association of polymorphisms in interleukin (IL)-1B-31, IL-1B-511, and IL-1Ra with ITP. Methods: Genotyping of IL-1B-31, IL-1B-511, and IL-1Ra was performed in 118 ITP patients and 100 controls by polymerase chain reaction restriction fragment length polymorphism and detection of variable number tandem repeats. Results: Genotype differences in IL-1B-31 and IL-1Ra were significantly associated with ITP. Patients showed a higher frequency of the IL-1B-31 variant allele (T) and a 1.52-fold greater risk of susceptibility to ITP (odds ratio [OR]=1.52, 95% confidence interval [CI]=1.04‒2.22, P=0.034). The frequencies of both homozygous and heterozygous variant geno-types of IL-1B-31 were higher (OR=2.33, 95% CI=1.069‒5.09, P=0.033 and OR=2.044, 95% CI=1.068‒39, P=0.034) among patients and were significantly associated with ITP susceptibility. Both homozygous and heterozygous variant genotypes of IL-1Ra were also more frequent (OR=4.48, 95% CI=1.17‒17.05, P=0.0230 and OR=1.80, 95% CI=1.03‒3.14, P=0.0494) among patients and were associated with ITP risk. IL-1B-31 and IL-1Ra also showed significant association with severe ITP. However, IL-1B-511 was not asso-ciated with ITP. Conclusion: IL-1B-31 and IL-1Ra polymorphisms may significantly impact ITP risk, and they could be associated with disease severity, which may contribute to the pathogenesis of ITP.

      • KCI등재후보

        Molecular Characterization of Rathi and Tharparkar Indigenous Cattle (Bos indicus) Breeds by RAPD-PCR

        Amit Kumar Sharma,Bharat Bhushan,Sanjeev Kumar,Pushpendra Kumar,Arjava Sharma,Satish Kumar 아세아·태평양축산학회 2004 Animal Bioscience Vol.17 No.9

        Random amplification of polymorphic DNA-Polymerase Chain Reaction (RAPD-PCR) analysis was carried out using DNA samples of 30 animals of Rathi cattle and 42 animals of Tharparkar cattle. Genomic DNA was isolated as per standard protocol and evaluated for its quality, purity and concentration. Twenty three random primers were screened out of which 15 primers yielded satisfactory amplifications and were used for further analysis. Average numbers of polymorphic fragments per primer were 7.07 0.86 in Rathi and 6.80 0.61 in Tharparkar cattle. The percentage of polymorphic bands in these two cattle breeds were 86 and 87%, respectively. Within breed genetic similarities for pooled over primers in the animals of Rathi and Tharparkar breeds were 0.577 0.30 and 0.531 0.02, respectively on the basis of band frequency (BF) and 0.645 0.04 and 0.534 0.04, respectively on the basis of band sharing (BS). Averages of between breed genetic similarities for pooled over primers were 0.97 and 0.92 according to BF and BS, respectively, which reflect higher degree of genetic similarity between Rathi and Tharparkar cattle breeds. Index of genetic distance based on BF and BS for pooled over primers was 0.030 0.011 and 0.088 0.031, respectively. Percentage of polymorphic bands and within-breed genetic similarities on the basis of band frequency (BF) and band sharing (BS) for pooled over primers revealed higher genetic similarity in Rathi than Tharparkar cattle population. High estimates of between breed genetic similarities for pooled over primers indicated that either Rathi is having decent from Tharparkar or both the cattle breeds are having common descent. Low value of Index of genetic distances between these two cattle breeds may be due to the fact that Rathi and Tharparkar cattle breeds are the native of Thar Desert in Northwest India. The results of between breed genetic distances also confirm the existence of high degree of genetic similarity between these two breeds of cattle.

      • KCI등재

        Magneto-transport Properties of La_(0.80)Sr_(0.20)Mn_(1−x)Cu_xO_3 Thin Films Fabricated by Using Spray Pyrolysis

        Pawan Kumar,Rakesh Kumar Dwivedi,Pawan Kumar,Ravikant Prasad,Praveen Kumar Siwach,Hari Krishna Singh 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.1

        Thin films of La_(0.80)Sr_(0.20)Mn_(1−x)Cu_xO_3 with x = 0.00, 0.04, 0.08, 0.10, 0.15, and 0.20 were deposited on single-crystal LaAlO_3 (100) (LAO) substrates at 250 ± 10 ℃ by using a nebulized spray pyrolysis technique. Structural, surface, and transport characterizations were done by X-ray diffraction (XRD), atomic force microscopy (AFM) and the standard four probe technique, respectively. XRD patterns revealed the formation of single-phase polycrystalline films with a rhombohedral crystal structure. Cu substitution resulted in a uniform decrease in the metal insulator transition (T_(IM)) temperature up to x = 0.10, followed by a drastic decrease in T_(IM) for x = 0.15. Finally, the metal-insulator transition vanished for higher Cu concentrations (x = 0.20) in the observed temperature range. The variation in T_(IM) with the amount of added Cu is explained on the basis of the double exchange mechanism. Cu substitution has been found to perturb the Mn^(3+)-O-Mn^(4+) network and has a strong influence on T_(IM). The variation in resistivity maxima with temperature for different Cu concentrations showed a systematic trend up to x ∼ 0.10. We also explored the electrical conduction at T > T_(IM) in the framework of small polaron hopping in the adiabatic limit. The activation energy showed a strong dependence on the Cu concentration. The maximum magneto-resistance (MR) up to 10%, was observed for x = 0.15 at low temperatures.

      • KCI등재

        Antioxidant and Antimicrobial Efficacy of Sapota Powder in Pork Patties Stored under Different Packaging Conditions

        Pavan Kumar,Manish Kumar Chatli,Nitin Mehta,Om Prakash Malav,Akhilesh Kumar Verma,Devendra Kumar,Manjeet Rathour 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.3

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        The present study was undertaken to assess the efficacy of sapota powder (SP) as natural preservatives and its better utilization in food processing with the incorporation of various levels of SP (2, 4, and 6%) by replacing lean meat. Based on the sensory attributes, pork patties with 4% incorporation of SP was found optimum and selected for further storage studies with control under aerobic and modified atmosphere packaging at refrigeration temperature (4±1℃) for 42 days for assessing its antioxidant and antimicrobial efficiency. During entire storage period, indicators of lipid oxidative parameters such as thiobarbituric acid reactive substances (TBARS), free fatty acids (FFA) and peroxide value (PV) followed an increasing trend for control as well as treated products; however, treated product showed a significantly (p<0.05) lower value than control. A significantly lower (p<0.05) microbial count in treated patties than control was noted during entire storage. The sensory attributes are better retained in treated product as compared to control and even on 42nd day, overall acceptability of treated patties was found to fall in moderately acceptable category (5.95 in aerobic packets and 5.91 in modified atmosphere packets). Therefore SP has potential to enhance antioxidant and antimicrobial properties of pork patties during storage.

      • KCI등재

        Experimental Validation of an IoT Based Device Selective Power Cut mechanism Using Power Line Carrier Communication for Smart Management of Electricity

        Sumit Kumar Jindal,Kishan Kumar,Shulin Saraswat,Ajay Kumar,Sanjeev Kumar Raghuwanshi 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.1

        There is a huge diff erence between electricity production and its demand. In order to meet the requirements, a selective power cut is carried out which is currently based on area and time. Although this is a simplistic solution, it has many drawbacks such as the area gets completely deprived of even the very basic appliances such as lights and fans, which do not contribute signifi cantly to the power consumption. This creates a need to come up with a solution so that no one gets deprived of using basic appliances at any time and still be able to reduce power consumption to fulfi ll the ever-growing demand. This work has dealt with the same by implementing a device selective protocol which can selectively cut power of particular devices depending on their energy rating, power rating, manufacturer etc. by the use of power line carrier communication. Hence, revolutionizing the whole concept of area selective power cut to device selective power cut. Since, IoT refers to a network of devices or “Things”, this work incorporates the basic principles of IoT by essentially creating a network of devices which can communicate with each other, over low bandwidth.

      • KCI등재

        Thoracolumbar Vertebral Injuries with Neurological Deficit Treated with Posterior Decompression, Short Segment Pedicle Screw Fixation, and Interlaminar Fusion

        Sachin Kumar,Satish Kumar,Rajender Kumar Arya,Avinash Kumar 대한척추외과학회 2017 Asian Spine Journal Vol.11 No.6

        Study Design: Prospective clinical study. Purpose: The purpose of this study was to evaluate the effect of interlaminar fusion and short segment pedicle screw fixation on thoracolumbar vertebral injuries for preventing pain and post-traumatic kyphosis. Overview of Literature: The treatment of thoracolumbar injuries continues to be one of the most controversial areas in spine care. The main aim of surgical treatment is to decompress the spinal cord or nerve roots, realign the spine, and correct or prevent posttraumatic kyphosis. We evaluated the outcome of interlaminar fusion along with posterior decompression and short segment pedicle screw fixation in patients with thoracolumbar fractures with neurological deficit. Methods: Twenty-two patients with traumatic thoracolumbar vertebral injuries and neurological deficit underwent short segment pedicle screw fixation above and below the fractured vertebrae, posterior decompression, and interlaminar fusion using a bone graft. Results: All patients were followed up for 12 months postoperatively. The average operative time and blood loss was 142 minutes and 214 mL, respectively. Of the 22 patients, 14 recovered completely. Of the nine patients with American Spinal Injury Association (ASIA) grade A disease, two improved by 1 grade, whereas one each improved by grades 2, 3, and 4, and four did not recover. Radiologically, vertebral kyphosis angle improved from 20.91 preoperatively to 15.73 postoperatively, sagittal index improved from 24.77 to 18.73, the sagittal plane kyphosis angle improved from 17.45 to 11.41, regional angle kyphosis improved from 14.73 to 10.14, the superior inferior end plate angle from 16.14 to 13.00, and mean anterior body compression improved from 36.26 to 27.64 postoperatively. No implant failed and no patient had neurological deterioration. Conclusions: Short segment pedicle screw fixation with posterior decompression and interlaminar fusion provided considerable reduction in kyphosis, restored the vertebral height of patients with thoracolumbar vertebral injuries and neurological deficit, and prevented development of delayed kyphotic deformity.

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