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RISS 인기검색어
- 검색키워드
- 저자 : Kralick, F. (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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Design and Fabrication of a PDMS/Parylene Microvalve for the Treatment of Hydrocephalus
Jonghyun Oh,Gyuman Kim,Kralick, F.,Hongseok Noh IEEE 2011 Journal of microelectromechanical systems Vol.20 No.4
<P>We present a novel microvalve for the treatment of a pathological condition, i.e., hydrocephalus. This microvalve is made of polydimethylsiloxane/Parylene composite layer which has a 3-D dome petal shape. This geometry enables the microvalve to rectify fluid flow in the forward and backward directions. New microfabrication techniques such as dome-shaped SU-8 mold fabrication and excimer laser machining for valve opening have been investigated to build the proposed microvalve. The pressure drop versus flow rate characteristics of the fabricated microvalve was investigated through in vitro flow tests. The flow test results showed that a 10 × 10 microvalve array with a cross-cut opening shape (200 × 60 μm) was found to be optimal for the treatment of hydrocephalus.</P>
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Malignant Nerve Sheath Tumor of the Spinal Accessory Nerve: A Unique Presentation of a Rare Tumor
Omair A. Sheikh,Ann Reaves,Francis A. Kralick,Ari Brooks,Rachel E. Musial,James Gasperino 대한신경과학회 2012 Journal of Clinical Neurology Vol.8 No.1
Background Malignant peripheral nerve sheath tumors (MPNSTs), sarcomas originating from tissues of mesenchymal origin, are rare in patients without a history of neurofibromatosis. Case Report We report a case of an MPNST of the spinal accessory nerve, unassociated with neurofibromatosis, which metastasized to the brain. The tumor, originating in the intrasternomastoid segment of the spinal accessory nerve, was removed. Two years later, the patient presented with focal neurological deficits. Radiographic findings revealed a well-defined 2.2×2.2×2.2 cm, homogeneously enhancing mass in the left parieto-occipital region of the brain surrounded by significant vasogenic edema and mass effect, culminating in a 1-cm midline shift to the right. The mass was surgically removed. The patient had nearly complete recovery of vision, speech, and memory.Conclusions To our knowledge, this is the first documented case of an MPNST arising from an extracranial segment of the spinal accessory nerve and metastasizing to the brain.
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