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α상분율의 변화가 층상조직 TiAl 합금의 열적안정성에 미치는 영향
金聖雄,이호년,吳明勳,山口正治,韋當文 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.6
The thermal stability of lamellar microstructure in TiAl-Mo PST crystals containing C or Si was investigated. In addition, the variation of α-phase volume fraction in Ti-Al-Mo-(C, Si) systems was also investigated at several temperatures. It was found that Ti-46Al-1.5Mo-O.2C and Ti-46Al-1.5Mo-1.0Si alloys were very stable during heat treatments at various heating rates and temperatures. Moreover, the, α-phase volume fraction of Ti-46A1-1.5Mo-0.2C and Ti-46A1-1.5Mo-1.OSi alloys (stable composition) was less changed than those of Ti-47Al and Ti-46Al-1.5Mo alloys (unstable composition). From these results, the instability of the latter alloys was thought to be resulted from relatively higher variation of α-phase volume fraction during heating. Therefore, it could be suggested that the variation of α-phase volume fraction is an important factor that control the thermal stability of lamellar microstructure.
Kim, Woosung,Jang, Yoonyoung,Lim, Youn-Hee,Kim, Bung-Nyun,Shin, Choong Ho,Lee, Young Ah,Kim, Johanna Inhyang,Hong, Yun-Chul The Korean Society for Preventive Medicine 2020 예방의학회지 Vol.53 No.1
Objectives: Prenatal cadmium (Cd) exposure may be associated with attention-deficit/hyperactivity disorder (ADHD) in children. Therefore, the objective of this study was to examine the relationship between Cd exposure during gestation and ADHD at 6 years of age. Methods: As part of an ongoing cohort study (the Environment and Development of Children study), 479 mother-child pairs from Seoul, Korea were included for analysis between 2008 and 2011. The whole blood concentration of Cd was analyzed using atomic absorption spectrophotometry. The parents were surveyed about ADHD behaviors in their children at age 6. Multivariable linear regression models were used to investigate the relationship between prenatal exposure to Cd and ADHD at 6 years of age. Results: Increased prenatal Cd concentrations were associated with increased scores for ADHD for girls, but not for boys, at age 6. A 2-fold increase in the prenatal Cd level was significantly associated with a 22.3% (95% confidence interval, 11.6 to 34.1) increase in ADHD in girls at 6 years of age, as indicated by the linear regression model. Conclusions: Our results identified significant associations between prenatal Cd exposure and ADHD scores in 6-year-old girls.
Kim, Johanna Inhyang,Kim, Jae-Won,Lee, Jong-Min,Yun, Hyuk Jin,Sohn, Chul-ho,Shin, Min-Sup,Kim, Bongseog,Chae, Jonghee,Roh, Jaewoo,Kim, Bung-Nyun Elsevier 2018 Progress in neuro-psychopharmacology & biological Vol.82 No.-
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>The dopamine receptor D2 receptor (<I>DRD2</I>) gene and lead exposure are both thought to contribute to the pathophysiology of attention-deficit/hyperactivity disorder (ADHD). ADHD is characterized by delay in brain maturation, most prominent in the prefrontal cortex (PFC). The D2 receptor is also mainly located in the PFC, and animal studies show that lead exposure affects the dopaminergic system of the frontal lobe, indicating an overlap in neural correlates of ADHD, <I>DRD2</I>, and lead exposure. We examined the interaction effects of <I>DRD2</I> rs1800497 and lead exposure on the cortical thickness of the frontal lobe in patients with ADHD.</P> <P><B>Methods</B></P> <P>A 1:1 age- and gender-matched sample of 75 participants with ADHD and 75 healthy participants was included in the analysis. The interaction effects of <I>DRD2</I> and lead exposure on the cortical thickness of 12 regions of interest in the frontal lobe were examined by multivariable linear regression analyses.</P> <P><B>Results</B></P> <P>When we investigated the <I>DRD2</I> ×lead effects in the ADHD and HC groups separately, significant <I>DRD2</I> ×lead effects were found in the ADHD group, but not in the healthy control group in multiple ROIs of the frontal lobe. There was a significant negative correlation between the cortical thickness of the right superior frontal gyrus and inattention scores.</P> <P><B>Conclusions</B></P> <P>The present findings demonstrated significant interaction effects of <I>DRD2</I> and lead exposure on the cortical thickness of the frontal lobe in ADHD. Replication studies with larger sample sizes, using a prospective design, are warranted to confirm these findings.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The dopamine receptor D2 receptor (<I>DRD2</I>) gene and lead exposure contribute to the pathophysiology of ADHD. </LI> <LI> Previous study results indicate an overlap in the neural correlates of ADHD, <I>DRD2</I>, and lead exposure in the prefrontal cortex. </LI> <LI> We found significant interactions between <I>DRD2</I> and lead exposure on the cortical thickness of the frontal lobe in ADHD patients. </LI> <LI> This study highlights the need for consideration of gene-environment interaction when conducting studies regarding dopamine-related genes. </LI> </UL> </P>
Kim, Sungjin,Kim, Kijun,Kim, Hyun-Jong,Lee, Ho-Nyun,Park, Tae Joo,Park, Young Min Elsevier 2018 ELECTROCHIMICA ACTA Vol.276 No.-
<P><B>Abstract</B></P> <P>Herein, we assessed the capabilities of NiO and Ni(OH)<SUB>2</SUB> electrodes for <SMALL>L</SMALL>-lactic acid sensing and compared the performances of the corresponding non-enzymatic sensors. Specifically, NiO and Ni(OH)<SUB>2</SUB> sensors showed high sensitivities, 9.08 and 35.76 μA/(mM cm<SUP>2</SUP>) and low detection of limit, 0.53 and 0.59 mM, respectively. Both sensors also show good selectivity and being insensitive to interferents such as <SMALL>L</SMALL>-ascorbic acid, uric acid, and dopamine. Furthermore, electrochemical characterization at variable scan rates revealed that NiO achieves faster sensing than Ni(OH)<SUB>2</SUB>, implying that the above electrodes exhibited different sensing mechanisms. Thus, X-ray photoelectron spectroscopy analysis confirmed that the NiO electrode inherently contained Ni<SUP>3+</SUP> ions acting as active sites for lactate detection and therefore increasing the response speed, whereas Ni(OH)<SUB>2</SUB> contained no Ni<SUP>3+</SUP> and had to be electrochemically converted into NiOOH prior to analyte detection. Consequently, the NiO electrode provided faster and more reliable lactate sensing, thus exhibiting promising non-enzymatic lactate sensor.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Lactate sensing performances of NiO and Ni(OH)<SUB>2</SUB> electrodes were probed and compared. </LI> <LI> Both sensors showed high sensitivity and selectivity, as well as low detection limits. </LI> <LI> NiO allowed faster sensing than Ni(OH)<SUB>2</SUB>. </LI> <LI> Electrochemical analysis reveal that NiO and Ni(OH)<SUB>2</SUB> electrodes exhibited different sensing mechanisms. </LI> <LI> XPS analysis showed that NiO inherently contained Ni<SUP>3+</SUP> ions, whereas Ni(OH)<SUB>2</SUB> did not. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Two New Records of Crangonid Shrimps (Crustacea: Decapoda: Caridea) in Korean Waters
Kim, Jung-Nyun,Choi, Jung-Hwa,Choi, Kwang-Ho,Kim, Sung-Tae,Chang, Dae-Soo The Korean Society of Systematic Zoology 2008 Animal Systematics, Evolution and Diversity Vol.24 No.3
Two crangonid shrimps, Paracrangon abei Kubo, 1937 and Pontocaris sibogae (De Man, 1918), collected from the northeastern and southeastern waters of Jeju Island, are newly recorded into the Korean fauna. The former is the second species and the latter is the only species of each genus recorded in Korea. Morphological and distributional accounts of these two species are briefly discussed.
김명환,김영환,김효정,이성구,서동완,최호순,이승규,유병무,민영일,고문수,민병철,이미화,임미경,김표년 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.1
Background/Aims: Choledochal cyst is a congenital dilatation of extraor intrahepatic bile duct . Recently, anomalous union of pancreaticobiliary duct(AUPBD) is supposed to be one of the major causes of choledochal cyst. The aims of this study are to assess the association ratio of AUPBD in choledochal cyst and whether the AUPBD in choledochal cyst have a clinical significance. Methods: The study subjects were 35 adult patients who were diagnosed by ERCP in Asan Medical Center from August, 1990 to July, 1995. We have classified the type of choledochal cyst and AUPBD according to Todani and Kimura, respectively. Result: The number of choledochal cyst was 14 cases(40%) in type I, I case(3%) in type II, 6 cases(17%) in type Ⅲ, 11 cases(31%) in type IVA. Three cases were unclassified. Among the 35 cases, 22 cases(63%) of choledochal cyst were associated with AUPBD. AUPBD was only seen in type I, IVA and unclassified form of choledochal cyst. The number of patients with type 1 AUPBD was 10(45%) and type 2 was 12(55%) by Kimura's classification. 'Che mean age was younger in patients with choledochal cyst and AUPBD(36.2 16 years) than in choledochal cyst aione(49.3 19 years). Acute inflammation and malignancy of biliary tree 8z pancreas were more commonly seen in patients with choledochal cyst and AUPBD than choledochal cyst alone. Conclusion: In patients with choledochal cyst, the association of AUPBD was not uncommon and they had more grave clinical course. AUPBD may be a contributing factor to develop mali~ancy in patiehts with choledochal cyst.