암시가속교수학습의 이론적 근거 및 교육적 시사점

김유미 中央大學校 韓國敎育問題硏究所 2000 韓國敎育問題硏究所論文集 Vol.- No.15

The purpose of this study was to introduce suggestopedia and inquire its educational implication. For this purpose, this study summarized the concept, development, and brain physiological basis of suggestopedia, criticized the data and research method of suggestopedia, examined main techniques and stages, and drew conclusion. Suggestopedia is a method, according to which the teacher, through the elimination and avoidance of all factors that might inhibit learning and the incorporation of all factors which promote learning in the interactive teaching and learning environment on the conscious and, even more importantly, unconscious levels of communication enables the student to attain higher levels of learning than when the unconscious level of communication is not used to the same extent as is conscious level. Lozanov originally developed suggestopedia for teaching-learning the foreign language in Bulgaria, but recently research projects using suggestopedia have sprung up worldwide with remarkable results across cognitive and affective areas. The brain physiological basis of suggestopedia as follows: 1) Joy through phychologically relaxed alertness and the absence of states of tension such as fear, stress, exhaustion, boredom, or irritation. 2) Unity of the conscious and unconscious in the form of verbal and non-verbal communication, of cortical and subcortical process, of physiological and psychological reactions, and of rationality and emotions. 3) Suggestive interaction between teacher and student through the desuggestion of learning barriers and the suggestion of learning potentiality. In spite of critical commentary on suggestopedia, it has educational implication on classroom teaching and learning.

다층모형을 활용한 아동청소년기 사회적 위축의 종단변화와 영향요인 분석

황예린,김유미 이화여자대학교 교육과학연구소 2022 교육과학연구 Vol.53 No.3

본 연구의 목적은 아동청소년의 사회적 위축 변화 양상 및 이에 영향을 미치는 요인을 확인하는 데 있다. 이러한 연구목적을 위해 한국복지패널 10차, 13차, 16차 조사에 모두 참여한 아동청소년 312명의 자료를 활용하여 다층모형으로 분석하였다. 수집된 자료는 SPSS 25.0과 HLM 6.0을 사용하여 분석하였다. 연구 결과 첫째, 아동청소년의 사회적 위축은 6년간 유의미하게 증가하는 것으로 확인되었다. 둘째, 우울ㆍ불안, 주의력 결핍 및 주관적 안녕감이 아동청소년의 사회적 위축 초깃값에 유의미한 영향을 미치는 것으로 나타났다. 셋째, 우울ㆍ불안, 주의력 결핍이 아동청소년의 사회적 위축 변화율에 유의미한 영향을 미치는 것으로 나타났다. 본 연구에서는 이러한 결과를 통해 아동청소년 사회적 위축 감소 및 이를 위한 개입 방안에 시사점을 제시하였다. The purpose of this study was to identify the longitudinal changes in the social withdrawal of children and adolescents and the variables affecting them. For this research purpose, the data of 312 children and adolescents who participated in the 10th, 13th, and 16th surveys of the Korean Welfare Panel were analyzed using a multi-level model. The collected data were analyzed with SPSS 25.0 and HLM 6.0. As a result, first, it was confirmed that the social withdrawal of children and adolescents significantly increased over 6 years. Second, it was found that anxiety and depression, attention deficit, and subjective well-being had a significant effect on the initial social withdrawal values of children and adolescents. Third, it was found that anxiety and depression and attention deficit had a significant effect on the rate of change in social withdrawal in children and adolescents. The implications of these results are discussed.

명상 기반 인지행동 프로그램이 아동의 우울성향에 미치는 영향

박정원,김유미 이화여자대학교 교육과학연구소 2009 교육과학연구 Vol.40 No.1

The purposes of this study were to examine the effects of meditation-based cognitive-behavioral program on children's depressive disposition. The subjects were 60 students in fifth-grade who had been randomly assigned to experimental group and control group. Prior to the experimental treatment, depression inventory was administered. And then experimental group was treated with meditation-based cognitive-behavioral program. The program lasted for 15 sessions during 8 weeks. In order to test the effects of meditation-based cognitive-behavioral program, posttest was administered after the treatment. The results were analyzed by using MANOVA, repeated MANOVA, independent t-test, and paired t-test. The findings of the study were as follows: First, it showed that teachers could develop and apply meditation-based cognitive-behavioral program compatible with child development in elementary school. Second, compared to control group, experimental group showed significant reduction in depressive deposition. 본 연구의 목적은 초등학교 아동의 우울성향 감소를 위해 명상 기반 인지행동 프로그램을 개발하여 그 효과를 검증하려는 데 있다. 이러한 연구목적을 위해 명상, 인지행동치료 및 우울성향에 대해 논의한 후, 이를 기반으로 가설을 설정하고 실험에 착수하였다. 실험에 앞서 연구대상인 5학년 2개 학급을 대상으로 우울성향 검사를 실시하였다. 사전검사를 마친 후 각각 실험반과 통제반에 배정하고 15차시에 걸쳐 명상 기반 인지행동 프로그램을 실시하였다. 실험을 마친 후 사전검사와 동일한 사후검사를 실시 하였으며, 그 검증결과는 다음과 같다. 첫째, 초등학교에서 아동발달에 적합한 명상 기반 인지행동 프로그램의 개발 및 적용이 가능한 것으로 나타났다. 둘째, 명상 기반 인지행동 프로그램이 우울성향 감소에 긍정적인 것으로 나타났다.

요로 결석의 체외 충격파 쇄석술 : 단순 복부 사진을 이용한 성공률 예측의 효율성 Efficacy of the KUB in Predicting the Success Rate

이연희,김유미 단국대학교 1998 論文集 Vol.33 No.-

Background: To evaluate the efficacy of KUB according to size, location, shape of urinary stones in ESWL. Methods: In 149patients with urinary stones, we retrospectively reviewed KUB findings of stone size, location, shape and analyzed success rate of ESWL. Results: The overall success rate of ESWL in 149 cases was 89.9%. And the sucess rates of renal and ureter stones were 81.4% & 93.4% respectively. It was more successfully treated by ESWL when stone showed size below 2㎝, round shape and ureteropelvic junction(UVJ) location. Conclusions: The KUB is a useful imaging modality in evaluating the efficacy of ESWL of urinary stone.

Characteristics of the Germline <em>MEN1</em> Mutations in Korea: A Literature Review

Seong Cheol Lee,Jun Won Min,You-Me Kim1,Myung-Chul Chang 대한갑상선-내분비외과학회 2014 The Koreran journal of Endocrine Surgery Vol.14 No.1

Purpose: Multiple endocrine neoplasia type 1 (MEN-1) is an autosomal dominant disease caused by the <em>MEN1</em> germline mutation. We reviewed previous reports in order to sum-marize the characteristics of germline <em>MEN1</em> mutation in Korea.Methods: We retrieved the relevant literature regarding <em>MEN1</em> germline mutation in Korea using the Pubmed (<a href="http://www.pubmed.org/">http://www.pubmed.org/</a>) and Koreamed (<a href="http://www.koreamed.org/">http://www.koreamed.org/</a>) databases from 2000 to 2012. We evaluated the pedigree of the patients in order to exclude the same, repeated families. We collected all data on the types of mutations and clinical characteristics.Results: There were nine studies with 12 cases of <em>MEN1</em> mutations in Korea. Two cases were sporadic MEN-1. C.196_200dupAGCCC was reported in three families. There were six cases of frameshift mutation, three cases of missense mutation, two cases of nonsense mutation, and one case of splice site mutation. Five mutations were novel mutations not previously reported.Conclusion: We summarized the characteristics of germline <em>MEN1</em> mutations in Korea. Genetic testing of <em>MEN1</em> is rare in Korea; however, it will be useful in preclinical diagnosis and genetic counseling.

2021년 대한영상의학회 전공의 연차별 수련교과과정 체계화 구축 사업에서 개발한 위임가능 전문직무 (Entrustable Professional Activity)와 필수 핵심역량 평가항목 및 평가 가이드라인

Kim You Me,Choi Moon Hyung,Lee Jei Hee,Lim Yun-Jung,Kim Young Jin,Park Jeong Seon,홍수진,Oh Jung Suk,Park Ji Seon,이아름,Jung Seung Eun 대한영상의학회 2022 대한영상의학회지 Vol.83 No.2

급변하고 있는 의료환경에서 전공의에게 양질의 수련을 제공하기 위해 연차별 수련교과과정을 역량 중심으로 개선하고, 수련병원이 수련에 적합한 환경을 유지하도록 하는 것은 매우중요하다. 대한영상의학회는 그동안 수련체계 개선을 꾸준히 진행해 왔고, 전공의 역량평가와 지도전문의의 내용을 강화하여 역량 중심 전공의 수련체계 개선을 제시하였다. 현재 대한영상의학회는 2021년 7월 제2차 연차별 수련교과과정 체계화 구축 사업에 선정되어 구축 사업을 추진하고 있으며, 구축 사업에서 요구하는 위임가능 전문직무와 핵심역량 평가항목 및평가 가이드라인을 개발하였다. 이에 대한 개발과정과 평가항목 및 평가 가이드라인을 소개하여 전공의와 지도전문의들에게 정보를 제공하고자 한다.

Classification of Korean rice varieties based on growth characteristics

Me-Sun Kim,Hye-Jung Lee,Dal-A Yu,Joonki Kim,Franz Nogoy,Eun-Ju Jeong,Jang-Hwan You,Yong-Gu Cho 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

The International Union for the Protection of New Varieties of Plants (UPOV) promotes an effective system of plant variety protection and encourages the development of new varieties of plants. International convention was initiated to standardized the system efforts and strengthen the policy. This study was conducted to establish a database for rice identification using morphological characters which include number of tillers and panicle per plant, spikelets per panicle, yield, plant maturity, height, leaf pigments, flag leaf angles, and rice bran. The whole rice population was grouped into three based on leaf angles, majority members of which retained the flag leaf angle-character until maturity stage. Most rice accessions did not exhibit anthocyanin pigments on the leaves particularly on the first leaf, leaf blade, leaf sheath and auricle, except for varieties classified as black rice. In the case of grain, many accessions produced secondary branching, and showed no awn. For agronomic traits, productive tiller and panicle per plant were higher in early flowering varieties, while spikelets per panicle and ripened grain were higher in late flowering varieties, and yield was higher in medium flowering varieties. All data were then pooled for cluster analysis which revealed three major independent clusters and four minor clusters.

Gut commensal-derived extracellular vesicles and cancer prevention in animal model

You-Me Kim 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

Interaction between intestinal commensal bacteria and the host exerts major influence on the organismal homeostasis and disease pathogenesis. In cancer, certain commensal bacteria can directly trigger tumorigenesis and different types of tumor tissues have been shown to harbor several bacteria species inside. On the other hand, intestinal bacteria composition is a key factor determining the effectiveness of cancer treatment such as chemotherapy, radiotherapy, and immunotherapy. Especially, responsiveness to immune checkpoint inhibitors critically depends on the intestinal microbiota and currently several clinical trials are underway to enhance therapeutic efficacy of anti- PD-1 or anti-PD-L1 antibodies by administering a single or a mixture of specific intestinal bacteria species or even by transplanting fecal material collected from cancer survivors who benefited from those immune checkpoint therapeutics. Despite the huge enthusiasm for utilizing commensal bacteria for cancer therapy, side effects and long-term consequences of taking a high dose of live bacteria still need further characterization. To overcome a risk posed by proliferating live bacteria, bacterial extracellular vesicles (EVs) may serve as an alternative. Bacterial EVs are membrane-enclosed particles actively secreted by live bacteria. EVs are generally of 20-200 nm in size and contain various bacterial macromolecules and metabolites. Compared to whole bacteria, EVs can be easily transported across epithelial cell layers to reach the systemic circulation and may confer the same beneficial effect to host as the whole bacteria. In this talk, I will present our recent results demonstrating that EVs isolated from a certain gut commensal bacterial strain significantly boost anti-cancer immune response and can be potentially developed for cancer prevention and treatment.

General rules for functional microRNA targeting

Kim, Doyeon,Sung, You Me,Park, Jinman,Kim, Sukjun,Kim, Jongkyu,Park, Junhee,Ha, Haeok,Bae, Jung Yoon,Kim, SoHui,Baek, Daehyun Nature Pub. Co 2016 Nature genetics Vol.48 No.12

<P>The functional rules for microRNA (miRNA) targeting remain controversial despite their biological importance because only a small fraction of distinct interactions, called site types, have been examined among an astronomical number of site types that can occur between miRNAs and their target mRNAs. To systematically discover functional site types and to evaluate the contradicting rules reported previously, we used large-scale transcriptome data and statistically examined whether each of approximately 2 billion site types is enriched in differentially downregulated mRNAs responding to overexpressed miRNAs. Accordingly, we identified seven non-canonical functional site types, most of which are novel, in addition to four canonical site types, while also removing numerous false positives reported by previous studies. Extensive experimental validation and significantly elevated 3' UTR sequence conservation indicate that these non-canonical site types may have biologically relevant roles. Our expanded catalog of functional site types suggests that the gene regulatory network controlled by miRNAs may be far more complex than currently understood.</P>

Type I and III interferon responses in SARS-CoV-2 infection

Kim You-Me,Shin Eui-Cheol 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

Coronavirus disease 2019 (COVID-19), the current pandemic disease, is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Type I and III interferons (IFNs) are innate cytokines that are important in the first-line defense against viruses. Similar to many other viruses, SARS-CoV-2 has evolved mechanisms for evading the antiviral effects of type I and III IFNs at multiple levels, including the induction of IFN expression and cellular responses to IFNs. In this review, we describe the innate sensing mechanisms of SARS-CoV-2 and the mechanisms used by SARS-CoV-2 to evade type I and III IFN responses. We also discuss contradictory reports regarding impaired and robust type I IFN responses in patients with severe COVID-19. Finally, we discuss how delayed but exaggerated type I IFN responses can exacerbate inflammation and contribute to the severe progression of COVID-19.