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정용규(Yong-Gyu Jung),김운섭(Un-Seob Kim) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1A
전자문서교환(EDI, Electronic)은 기업과 기업간에 컴퓨터와 컴퓨터의 통신을 통하여 필요한 거래문서를 구조화된 형식으로 교환하여 업무를 처리하는 방식을 말한다. 그동안 EDI 표준은 북미를 중심으로 한 ANSI X.12를 시작으로, 이에 대응되는 유럽중심의 UN/CEFACT 표준이 제정되었다. UN/CEFACT로 표준을 통합하기로 합의한 양대 표준은 또 다른 XML환경을 접하게 되었다. ISO TC154에서는 UN/CEFACT전자문서의 XML변환에 관한 논의하게 되었으나 표준으로 권고되지 못하고 있는 실정이다. 이런 표준간 연동의 문제를 위하여 본 논문에서는 Speaking Tag방식과 UN/CEFACT Tag방식의 두가지를 제안하며 각각에 대해 변환규칙을 제안한다.
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Improvement of fibrosed scar tissue elongation using self-inflatable expander
Jung, Gyu-Un,Kim, Jin-Woo,Pang, Eun-Kyoung,Kim, Sun-Jong The Korean Dental Association 2016 대한치과의사협회지 Vol.54 No.7
We evaluated a self-inflatable osmotic tissue expander for its utility in creating sufficient soft tissue elongation for primary closure after bone grafting. Six patients with alveolar defects who required vertical augmentation of >6 mm before implant placement were enrolled. All had more than three prior surgeries, and flap advancement for primary coverage was restricted by severely fibrosed scars. Expanders were inserted beneath the flap and fixed with a screw. After 4 weeks, expander removal and bone grafting were performed simultaneously. A vertical block autograft and guided bone regeneration and distraction osteogenesis were performed. Expansion was sufficient to cover the grafted area without additional periosteal incision. Complications included mucosal perforation and displacement of the expander. All augmentation procedures healed uneventfully and the osseous implants were successfully placed. The tissue expander may facilitate primary closure by increasing soft tissue volume. In our experience, this device is effective, rapid, and minimally invasive, especially in fibrous scar tissue.
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Kim, Cheolmin,Lee, Inae,Jung, Dawoon,Hong, Seongjin,Khim, Jong Seong,Giesy, John P.,Yim, Un Hyuk,Shim, Won Joon,Choi, Kyungho Elsevier 2017 CHEMOSPHERE - Vol.168 No.-
<P><B>Abstract</B></P> <P>Oil spills near the coastlines may damage marine and intertidal ecosystem. Constituents of the oil have been reported to cause toxic consequences mediated by aryl hydrocarbon receptor (AhR), and estrogen receptor (ER). In the present study, AhR– and ER–mediated toxicities of coastal sediments of Taean were investigated seven years after <I>Hebei Spirit</I> oil spill (HSOS). Sediment samples were collected on June and October 2014 from seven locations along the Taean coastline, where signs of oil spill were detected. Sediment samples were extracted in Soxhlet extractors and further processed through activated silica gels to separate into four fractions; F1 (saturate hydrocarbons), F2 (aromatic hydrocarbons), F3 (resins and polar compounds), and F4 (residues). ER–mediated and AhR–mediated potencies (% E2<SUB>max</SUB> and % TCDD<SUB>max</SUB>) of each fraction were determined using MVLN cells and H4IIE-<I>luc</I> cells, respectively. F2 and F3 fractions of Sinduri 1, Sinduri 2, and Sogeunri 1 samples showed greater AhR–mediated potencies (up to 107% TCDD<SUB>max</SUB>). Chemical analysis revealed that PAH components are correlated with AhR–binding activities. The % E2<SUB>max</SUB> results varied by sample: While there was no noticeable induction of ER–dependent responses (<45%), some aromatics fractions (F2) exhibited the highest ER–mediated responses. Compared with previous reports from the same sites, both AhR–mediated and ER–mediated potencies have decreased over time. Nevertheless, AhR–mediated potencies could be identified in the environmental samples even after 7 years of the incident. Therefore, possible ecosystem implications of these findings should be further investigated.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Dioxin-like toxicities were found in sediments affected by <I>Hebei Spirit</I> oil spill. </LI> <LI> Fractionized samples could not explain toxicities observed in whole extracts. </LI> <LI> Toxicity interactions of oil components are suspected in sediment samples of HSOS. </LI> <LI> Follow-up of mechanism-based bioassays combined with chemical analyses is required. </LI> </UL> </P>
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Kim, Donghwi,Jung, Jee-Hyun,Ha, Sung Yong,An, Joon Geon,Shankar, Ravi,Kwon, Jung-Hwan,Yim, Un Hyuk,Kim, Sung Hwan Elsevier 2019 CHEMOSPHERE - Vol.237 No.-
<P><B>Abstract</B></P> <P>In this study, developmental toxicity was increased as the oil was further degraded under natural sunlight. Detailed chemical composition of the degraded oils was examined by use of gas chromatography (GC) and (−) electrospray ionization ultrahigh resolution mass spectrometry (UHR-MS). Baseline toxicities were estimated based on chemical activities of polycyclic aromatic hydrocarbons, and it was obvious that the predicted chemical activities can not explain increased toxicity alone. However, the ultrahigh resolution mass spectral abundance of polar compounds including O<SUB>3</SUB> and O<SUB>4</SUB> class compounds was significantly increased as the photodegradation proceeded. Further examination of double bond equivalence values of the compounds showed that polar compounds with both non-aromatic and aromatic polar structures were increased. Statistical analysis indicates that the increased toxicity can be well explained by the increased polar compounds. Therefore, the oxygenated compounds identified in this study can play an important role in toxicity of degraded oils.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Molecules generated by photooxidation and contributing to toxicity were identified. </LI> <LI> Polar compounds detected by UHR-MS were increased x 4 in 5 day of photooxidation. </LI> <LI> Toxicity was greatly increased as oils were photodegraded under natural sunlight. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Kim, Young-Je,Jung, Un Ju MDPI 2019 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.20 No.9
<P>This study focuses on the effect of honokiol (HON) on glucose homeostasis, insulin resistance, dyslipidemia, hepatic steatosis, and inflammation in type 2 diabetic <I>db</I>/<I>db</I> mice. Male C57BL/KsJ-<I>db</I>/<I>db</I> mice were fed a normal diet with or without HON (0.02%, <I>w</I>/<I>w</I>) or pioglitazone (PIO, anti-diabetic agent, 0.01%, <I>w</I>/<I>w</I>) for 5 weeks. Blood biomarker, tissue morphology and enzymatic and genetic parameters were determined. PIO significantly decreased food intake, fasting blood glucose, and glycosylated hemoglobin (HbA1c) levels, but markedly increased body weight, adipose tissue weight, and plasma leptin levels. HON did not significantly affect food intake, body weight, or levels of plasma leptin and blood glucose. However, HON led to significant decreases in adipose tissue weight, plasma insulin, blood HbA1c and HOMA-IR levels and improved glucose tolerance. The anti-diabetic and anti-adiposity effects of HON were partially related to the inhibition of gluconeogenic enzymes and their mRNA expression in the liver; and the inhibition of lipogenic enzymes in adipose tissue, respectively. Unlike PIO, HON did not affect dyslipidemia, but ameliorated hepatic steatosis by inhibiting hepatic lipogenic enzymes activity. Moreover, HON exhibited anti-inflammatory effects similar to PIO. These results suggest that HON can protect against type 2 diabetes by improving insulin resistance, glucose and lipid metabolism, and inflammation.</P>
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Kim, Young-eun,Im, Hyo Been,Jung, Un Ho,Park, Ji Chan,Youn, Min Hye,Jeong, Heon-Do,Lee, Dong-Wook,Rhim, Geun Bae,Chun, Dong Hyun,Lee, Ki Bong,Koo, Kee Young Elsevier 2019 Fuel Vol.256 No.-
<P><B>Abstract</B></P> <P>The linear α-olefin 1-octene was produced via the dehydration of 1-octanol over Al<SUB>2</SUB>O<SUB>3</SUB> catalysts. The effect of calcination temperature on the characteristics of an Al<SUB>2</SUB>O<SUB>3</SUB> catalyst and its activity in the dehydration of 1-octanol to 1-octene was investigated. Al<SUB>2</SUB>O<SUB>3</SUB> catalysts calcined at various temperatures (250, 500, 750, 1000 °C) were evaluated at 300–400 °C with a liquid hourly space velocity (LHSV) of 7–56 h<SUP>−1</SUP>. XRD, BET, <SUP>27</SUP>Al-NMR, Py-FTIR, and NH<SUB>3</SUB>-TPD analyses indicated that the calcination temperature affected the crystal phase, surface area, occupancy of the coordinated Al<SUP>3+</SUP> ion, and acidic properties of Al<SUB>2</SUB>O<SUB>3</SUB> catalysts. Upon calcination at temperatures >750 °C, the surface area of Al<SUB>2</SUB>O<SUB>3</SUB> catalysts reduced due to γ-Al<SUB>2</SUB>O<SUB>3</SUB> to θ-Al<SUB>2</SUB>O<SUB>3</SUB> phase transition. The changes in the crystal phase decreased the surface area, which correlated to the acidity of the Al<SUB>2</SUB>O<SUB>3</SUB> catalyst. The distribution of unsaturated Al<SUP>3+</SUP> ions acting as LAS on the catalyst surface increased with increasing calcination temperature, but decreased above 750 °C calcination temperature due to the diminishing surface area. The Al<SUB>2</SUB>O<SUB>3</SUB> catalyst calcined at 500 °C showed the highest 1-octanol conversion in the dehydration of 1-octanol. High 1-octene selectivity was maintained while the isomer ratio decreased at a high LHSV of 56 h<SUP>−1</SUP>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Linear α-olefin 1-octene produced via dehydration of 1-octanol over Al<SUB>2</SUB>O<SUB>3</SUB> catalyst. </LI> <LI> Changes in crystal phase affected the strong LAS and catalytic activity of Al<SUB>2</SUB>O<SUB>3</SUB>. </LI> <LI> Increased strong LAS improved 1-octanol conversion and 1-octene yield. </LI> <LI> Octene isomers decreased while DOE increased at higher LHSV. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Jung, Jong-myung,Lee, Si Un,Hyun, Seung-Jae,Kim, Ki-Jeong,Jahng, Tae-Ahn,Oh, Chang Wan,Kim, Hyun-Jib The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.1
Objective : This study aimed to determine the incidence and analyze trends of the herniated lumbar disc (HLD) based on a national database in the Republic of Korea (ROK) from January 2008 to December 2016. Methods : This study was a retrospective analysis of data obtained from the national health-claim database provided by the National Health Insurance Service for 2008-2016 using the International Classification of Diseases. The crude incidence and age-standardized incidence of HLD were calculated, and additional analysis was conducted according to age and sex. Changes in trends in treatment methods and some treatments were analyzed using the Korean Classification of Diseases procedure codes. Results : The number of patients diagnosed with HLD was 472245 in 2008 and increased to 537577 in 2012; however, it decreased to 478697 in 2016. The pattern of crude incidence and the standardized incidence were also similar. Overall, the incidence of HLD increased annually for the 30s, 40s, 50s, and 70s until 2012 and then decreased. However, the incidence of HLD for the 80s continued to increase. The crude incidence of HLD in female patients exceeded that of male patients in their middle age (30s or 40s) and was 1.5-1.6 times higher than in male patients in their 60s. The total number of open discectomy (OD) increased from 71598 in 2008 to 93942 in 2012 and then decreased to 85846 in 2016. The rate of younger patients (the 20s, 30s, and 40s) who underwent OD was decreased, and the rate of younger patients who underwent percutaneous endoscopic lumbar discectomy was increased. However, the rate of older patients (the 70s and 80s) who underwent OD was continuously increased. Conclusion : This nationwide data on HLD from 2008 to 2016 in the ROK demonstrated that the crude incidence and the standardized incidence increased until 2012 and then decreased. The annual crude incidence was different according to age and sex. These findings may be considered when deciding future health policy, especially in countries with a similar national health insurance system (or with plans to adopt).
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