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Everolimus-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Stenosis
PRECOMBAT-2 Investigators,Kim, Y.H.,Park, D.W.,Ahn, J.M.,Yun, S.C.,Song, H.G.,Lee, J.Y.,Kim, W.J.,Kang, S.J.,Lee, S.W.,Lee, C.W.,Park, S.W.,Jang, Y.,Jeong, M.H.,Kim, H.S.,Hur, S.H.,Rha, S.W.,Lim, D.S. Elsevier 2012 JACC. Cardiovascular interventions Vol.5 No.7
Objectives: This study sought to evaluate the safety and efficacy of second-generation drug-eluting stents (DES) for patients with unprotected left main coronary artery (ULMCA) stenosis. Background: The clinical benefit of second-generation DES for ULMCA stenosis has not been determined. Methods: The authors assessed 334 consecutive patients who received everolimus-eluting stents (EES) for ULMCA stenosis between 2009 and 2010. The 18-month incidence rates of major adverse cardiac or cerebrovascular events (MACCE), including death, myocardial infarction (MI), stroke, or ischemia-driven target vessel revascularization (TVR), were compared with those of a randomized study comparing patients who received sirolimus-eluting stents (SES) (n = 327) or coronary artery bypass grafts (CABG) (n = 272). Results: EES (8.9%) showed a comparable incidence of MACCE as SES (10.8%; adjusted hazard ratio [aHR] of EES: 0.84; 95% confidence interval [CI]: 0.51 to 1.40; p = 0.51) and CABG (6.7%, aHR of EES: 1.40; 95% CI: 0.78 to 2.54; p = 0.26). The composite incidence of death, MI, or stroke also did not differ among patients receiving EES (3.3%), SES (3.7%; aHR of EES: 0.63; 95% CI: 0.27 to 1.47; p = 0.29), and CABG (4.8%; aHR of EES: 0.67; 95% CI: 0.29 to 1.54; p = 0.34). However, the incidence of ischemia-driven TVR in the EES group (6.5%) was higher than in the CABG group (2.6%, aHR of EES: 2.77; 95% CI: 1.17 to 6.58; p = 0.02), but comparable to SES (8.2%, aHR of EES: 1.14; 95% CI: 0.64 to 2.06; p = 0.65). Angiographic restenosis rates were similar in the SES and EES groups (13.8% vs. 9.2%, p = 0.16). Conclusions: Second-generation EES had a similar 18-month risk of MACCE for ULMCA stenosis as first-generation SES or CABG. (Evaluation of Outcomes of EES Implantation for Unprotected Left Main Coronary Artery Stenosis [PRECOMBAT-2]; NCT01348022)
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Dispersive Delay Lines Based on the Use Of Narrow Open Metal Reflectors and Fan-Shaped Transducers
( K. C. Lee1 V. P ),( Plessky2 S. M ),( Balashov ),( C. W. Nam ),( C. U. Kim ) 한국센서학회 2012 센서학회지 Vol.21 No.6
An in-line dispersive delay line (DDL) demands low and controllable reflectivity of the reflectors, especially if the surface acoustic wave (SAW) propagates all the way along the reflecting structure. The metal reflectors are usually too strong and introduce too much attenuation in such a device. The proposed solution of this problem is to spatially separate the acoustic channels for different frequencies with the help of Fan-shaped Transducers (FIDT) and to use narrow open metal reflectors to reduce reflectivity. Special arrangement of FIDT is performed to use 180-deg. reflection of the SAW. Narrow open metal strips with a metallisation ratio of the order of 20% are used as reflectors with small and controllable reflectivity. Reflectivity of such strips is estimated both theoretically and experimentally. Experimental performance of the proposed DDL is presented.
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