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Nguyen, Khanh Hoang Viet,Dao, Trong Khoa,Nguyen, Hong Duong,Nguyen, Khanh Hai,Nguyen, Thi Quy,Nguyen, Thuy Tien,Nguyen, Thi Mai Phuong,Truong, Nam Hai,Do, Thi Huyen Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.5
Objective: Fibronectin 3 (FN3) and immunoglobulin like modules (Ig) are usually collocated beside modular cellulase catalytic domains. However, very few researches have investigated the role of these modules. In a previous study, we have sequenced and analyzed bacterial metagenomic DNA in Vietnamese goats' rumen and found that cellulase-producing bacteria and cellulase families were dominant. In this study, the properties of modular cellulases and the role of a FN3 in unique endoglucanase belonging to glycosyl hydorlase (GH) family 5 were determined. Methods: Based on Pfam analysis, the cellulases sequences containing FN3, Ig modules were extracted from 297 complete open reading frames (ORFs). The alkaline, thermostability, tertiary structure of deduced enzymes were predicted by AcalPred, TBI software, Phyre2 and Swiss models. Then, whole and truncated forms of a selected gene were expressed in Escherichia coli and purified by His-tag affinity column for assessment of FN3 ability to enhance enzyme activity, solubility and conformation. Results: From 297 complete ORFs coding for cellulases, 148 sequences containing FN3, Ig were identified. Mostly FN3 appeared in 90.9% beta-glucosidases belonging to glycosyl hydrolase family 3 (GH3) and situated downstream of catalytic domains. The Ig was found upstream of 100% endoglucanase GH9. Rarely FN3 was seen to be situated downstream of X domain and upstream of catalytic domain endoglucanase GH5. Whole enzyme (called XFN3GH5 based on modular structure) and truncate forms FN3, XFN3, FN3GH5, GH5 were cloned in pET22b (+) and pET22SUMO to be expressed in single and fusion forms with a small ubiquitin-related modifier partner (S). The FN3, SFN3 increased GH5 solubility in FN3GH5, SFN3GH5. The SFN3 partly served for GH5 conformation in SFN3GH5, increased modules interaction and enzyme-soluble substrate affinity to enhance SXFN3GH5, SFN3GH5 activities in mixtures. Both SFN3 and SXFN3 did not anchor enzyme on filter paper but exfoliate and separate cellulose chains on filter paper for enzyme hydrolysis. Conclusion: Based on these findings, the presence of FN3 module in certain cellulases was confirmed and it assisted for enzyme conformation and activity in both soluble and insoluble substrate.
The Impacts of Intellectual Property Rights on International Trade Flows in ASEAN Countries
Nguyen Khanh Doanh 대구대학교 경제경영연구소 2006 경제경영연구 Vol.4 No.1
This paper aims at analyzing the impact of intellectual property protection on international trade flows, using ASEAN as a case study. The finding of the paper could be summarized as follows. First, IPR protection is an important determinant of international trade flows. Overall, stronger protection of IPRs increases bilateral trade between ASEAN and the rest of the world. Second, IPR protection in the importing countries (the rest of the world) has positive effect on ASEAN's exports, indicating the market expansion effect. When the impacts of IPR protection are allowed to differ across sectors, stronger effects on exports are found in high tech sectors, such as chemicals and transport equipment and machinery. Third, IPR protection in ASEAN countries has negative effect on their imports from the rest of the world, exhibiting the market power effect. When the impacts of IPR protection are allowed to differ across sectors, strong effects on ASEAN's imports are found in such sectors as food and manufactured goods. Implications being derived from this study are summarized as followed. First, industrializing countries with strong imitative capacities tend to experience the market expansion effect as their IPR regimes become stronger, while for developing countries with weak imitative abilities, the effects of stronger IPR protection in these countries on their imports are ambiguous. Second, most industrializing countries are those which should expect the largest adjustment in domestic output and labor as their fringing production activities are replaced progressively by foreign imports.
A Heading Estimation based on Smartphone Holding Styles
Khanh Nguyen Huu,KyungHo Lee,Chang Geun Song,Seon-Woo Lee 한국HCI학회 2016 한국HCI학회 학술대회 Vol.2016 No.1
In this paper, based on four different holding styles of a smartphone, which is determined using a set of inertial sensors included in the smartphone, we suggest an effective method to estimate the heading direction of a user while he is walking. The four main holding styles are divided into thirty six sub-cases, which can cover a very free style of a user holding a smartphone. The classification of holding styles can support to get better performance of heading estimation. Further, the performance of the proposed methods is verified experimentally.
Khanh Nguyen-Huu(웡후칸),Seon-Woo Lee(이선우) 한국HCI학회 2019 한국HCI학회 학술대회 Vol.2019 No.2
Recently, in the field of indoor localization, wireless radio and dead reckoning techniques are two main branches that received much attention. The former one uses the wireless facility such as WiFi or Bluetooth to estimate the user position in two ways: triangulation and fingerprinting. The latter one uses the inertial sensors to estimate the displacement of the user based on the previous position. In this paper, from several experiments, we pointed out the effect of WiFi scanning interval and pedestrian walking speed to the positioning result. We also used the WiFi fingerprinting technique as a clue to compensate for the accumulated error of the pedestrian dead reckoning system which is implemented on a smartphone to analyze the effect of the two factors above.
Khanh Pham,최현준,이동섭,김기석,최항석 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.6
In this study, a hydraulic-mechanical (H-M) coupling model was implemented, which considers porous media as a deforming porous continuum where fluid flow is taken into account. The primary variables are the time-dependent pore pressure and displacement of the solid skeleton. Physical laws, including the linear momentum balance and mass conservation, are applied to describe the corresponding processes as mechanics and fluid flow occurring within the porous media during the consolidation progress. The general field equations were derived with the aid of a finite element formulation and generalized trapezoidal method to deal with the governing equations in spatial and time domains. In the numerical analysis, the massive diversity of time domain of coupled problems was discussed in detail. In addition, a convergence condition for the partitioned approach applied to deal with a typical matter was proposed. A numerical example was executed to simulate a one-dimensional isothermal consolidation in which a hydraulic-mechanical coupling is mathematically adopted. Finally, a series of parametric studies was carried out to indicate the effect of Biot’s coefficient and fluid properties on the isothermal consolidation of porous media. The results of parametric studies show that the consolidation of porous media can be expedited with compressible particles and less compressible fluids than those with incompressible particles and more compressible fluids, respectively.
AN INDEPENDENT RESULT FOR ATTACHED PRIMES OF CERTAIN TOR-MODULES
Khanh, Pham Huu Korean Mathematical Society 2015 대한수학회보 Vol.52 No.2
Let (R, m) be a Noetherian local ring, I an ideal of R, and A an Artinian R-module. Let $k{\geq}0$ be an integer and $r=Width_{>k}(I,A)$ the supremum of length of A-cosequence in dimension > k in I defined by Nhan-Hoang [8]. It is shown that for all $t{\leq}r$ the sets $$(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/I^n,A)))_{{\geq}k}\;and\\(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/(a_1^{n_1},{\cdots},a_l^{n_l}),A)))_{{\geq}k}$$ are independent of the choice of $n,n_1,{\cdots},n_l$ for any system of generators ($a_1,{\cdots},a_l$) of I.
Khanh B. Vu,Thanh Khoa Phung,Thao T.T. Tran,Clement Mugemana,Ha N. Giang,Truong Le Phuc Nhi 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.97 No.-
Polystyrene was synthesized and applied as a template for fabricating hollow silica nanoparticles. Organic solvent and water were used as a solvent and an anti-solvent, respectively, to produce thepolystyrene nanoparticles via. nanoprecipitation technique. The influence of precipitation method (oneshotor drop), solvent for dissolution of polystyrene, and concentration of polystyrene or CTAB linker onthe diameter of polystyrene nanoparticles was investigated. The hollow silica nanoparticles werefabricated using the as-made polystyrene nanoparticles as a template with the help of CTAB linker. Polystyrene was recovered by the extraction of polystyrene@SiO2 composite with the tetrahydrofuransolvent, and the recovered polystyrene was re-used to make the polystyrene nanoparticles as a templatefor fabricating hollow silica nanoparticles. Our study can be applied for other types of polymericmaterials as long as those polymeric materials form nanoparticles via. nanoprecipitation technique. Incomparison with the polystyrene hard template prepared by emulsion polymerization, the size ofpolystyrene nanoparticles produced by the nanoprecipitation technique can be well-tuned by changingthe polystyrene and linker concentrations.