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      • KCI등재

        착화제와 유기산이 Wistar rat체내의 Sr 분포에 미치는 영향

        이기호,이제호,박상윤,이승훈,유용운,윤택구 대한방사선 방어학회 1990 방사선방어학회지 Vol.15 No.2

        Wistar rat에 85SrCl2를 꼬리 정맥에 주사하여 체내 기관과 혈액 내 분포, 잔존율을 조사하였고 착화제와 유기산을 투여하여 혈장 단백질에 결합하는 Sr양의 변화를 측정하였다. 혈액내에서 Sr은 혈장에 60%, 세포에 40%부착되어 이동하였다. 혈장에 존재하는 Sr중 약 50%정도는 혈장 단백질과 결합한 상태였고, 세표에는 세포 표면에 가볍게 부착되어 있었다. Erythrocyte나 granulocyte보다 lymphocyte에 많은 양의 Sr이 부착되어 있었다. 투여후 초기 1시간 이내에 혈액 내에서 급격히 감소하여 뼈에 침착되었다. 이때 각 기관에서도 Sr의 잔존율은 24시간 이내에 크게 감소하였고, 뼈로 침착된 Sr은 24시간 이후에 서서히 감소하였다. 착화제 EDTA, EGTA 및 DTPA를 투여한 경우, 혈장 단백질에 결합하는 Sr의 양은 대조군의 57%에서 27-33%로 감소하였으며 citrate 및 oxalate의 투여시는 이값이 19%와 40%로 각각 감소하였다. 85SrCl2 was injected to the tail vein of Wistar rats and investigated its distribution and clearance in the tissues and blood. We also measured the changes in Sr binding to the blood plasma protein by administrating chelating agents and organic acids. For the blood, 60% of the Sr occurred in the plasma and 40% on the cell membrane. Fifty percent of Sr in the blood plasma was bound to plasma protein. Sr on the cell membrane seemed to be bound loosely. The binding in the lymphocyte was higher than in the erythrocyte and granulocyte. Within one hour Sr was quickly disappeared from the blood stream, to be accumulated in the bone. Twenty four hours after the injection, Sr decreased rapidly in the organs of soft tissue, but slowly in the bone. The binding of Sr to plasma protien decreased from 57% of the control to 27-33% in the group treated with chelating agents. EDTA. EGTA and DTPA and to 19% and 40% in the groups treated with organic acids, citrate and oxalate, respectively.

      • 대장에 발생한 샘암종에서 MUC1과 MUC2 점소 발현의 의의

        이윤경,이주호,이용,심재영,박정훈,오수섭,박진실,기근홍 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Background : Mucins possess the unique function of protecting and lubricating the epithelial surface and other important functions such as call growth, direct implication in the fetal development, the epithelial renewal and differentiation, the epithelial integrity, carcinogenesis, immune regulation, cellular adhesion and metastasis. Purpose : This study was done to provide the significance of alteration of MUC1 and MUC2 expression in colorectal adenocarcinoma, A series of 131 colorectal adenocarcinomas including 11 mucinous carcinomas were screened immunohistochemically for their expression of MUCI and MUC2, Materials and mehtods : Of 131 carcinomas, 76 (58,5%) were MUCI positive and 91 (68, 9%) were MUC2 positive, In normal colonic goblet cells, MUCl was not expressed but MUC2 was expressed in cytoplasm, Conclusion There were up-regulation of MUCI and down-regulation of MUC2 in colorectal carcinomas, The frequency of MUC2 positivity according to differentiation was statistically reliable. (p=0.0001)

      • 인공호수 주변지역의 농업기후분석 : Ⅰ. 담수전 기온 및 강수량 분포 추정 Ⅰ. Monthly Temperature and Precipitation Pattern under No-lake Scenario

        김기철,윤진일 경희대학교 부설 식량자원개발연구소 1992 硏究論文集 Vol.13 No.-

        Changes in energy and water balance due to an artificial lake may bring about the local climatic change. Several occasions have already been reported about degradation of agricultural production environments at major dam construction sites in Korea. This study was carried out to quantify the potential effects of the inadvertent climate modification due to artificial lakes. For the first phase of the study, climatological normals were estimated for Juam region which is 20 × 30 km in size and affected by a large reservoir formed after a dam construction. Monthly mean temperature and precipitation values were calculated for each 250 × 250 m grid cell based on a statistical topoclimatic model developed by the Meteorological Research Institute under the 'No-lake scenario'. Six automated weather stations were installed for verification purpose in the second phase of the study. According to the calculated values, the distribution of mean temperature showed a decreasing pattern with the elevation, and the Lake Juam area was warmer than the surrounding region. Estimated values for precipitation differ by as much as 75mm from the observed value and the range of annual precipitation was 654 - 1852mm. The lower valley region where the Lake Juam is currently formed showed more precipitation than the surrounding mountains in general.

      • KCI등재

        국내산 및 제초제 내성 콩(HS2906)의 일반성분, 무기질 및 지방산 조성

        양윤형,이정희,김형진,윤원기,김환묵,김미리 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

        Proximate analysis, mineral and fatty acid composition of three conventional domestic soybean cultivars and two imported ones including glyphosate-tolerant HS2906 were evaluated by AOAC method, ICP-AES and gas chromatography. There were several differences in the proximate analysis among three conventional domestic soybean cultivars ; higher crude fat in the cultivar Hwanggumkong, higher crude protein in Pungsankong, and higher carbohydrate and crude ash in Duyukong. The ranges of contents of proximate components of domestic cultivars were similar to the data previously reported. There were no significant differences in proximate analysis between conventional soybean WS82 and glyphosate-tolerant HS2906 ; 23.55~23.90% of crudefat, 34.22~35.55% of crude protein, 6.25~6.45% of crude ash, and 25.35~26.47% of carbohydrate. The mineral and fatty acid compositions of HS2906 were similar to those of conventional soybeans previously reported.

      • 경희대학교 실습농장의 작물기간중 주요 기상요소의 일중변화

        김기철,윤진일 경희대학교 부설 식량자원개발연구소 1991 硏究論文集 Vol.12 No.-

        Local weather and climate characteristics are important to agricultural research and often play a crucial role in interpreting the data from field experiments. An automated weather station was used to monitor the hourly weather parameters at the Experimental Farm of Kyung Hee University during the 1991 crop season. The data were analyzed to figure out the mean monthly pattern of the 24-hour temporal changes in air and soil temperature, air humidity, wind, solar irradiance and rainfall over the farm field. A continentality rather than a maritinity seemed to control the temperature pattern in spite of the large water body near the farm site. Daily maximum air temperature was observed at 1500-1600 LST. The occurrence of soil temperature extremes was delayed by 2 hours compared with that of air temperature. Soil temperature was in general higher than the air temperature in May and June. Atmospheric vapor pressure was higher during daytime and the average pattern followed the seasonal air temperature variation. Wind was strong in spring and weakened in summer. Daytime wind speed was higher than nocturnal one over the whole season. There was a significant change in wind direction from southeasterlies in the daytime to northwesterlies in the night. Solar irradiance in July was only two thirds of that in May, the month of highest solar irradiance. The hourly distribution pattern was somewhat affected by the hourly rainfall incidence.

      • KCI등재

        수종의 상아질 결합체의 전단강도 및 결합부의 형태에 관한 비교연구

        김용기,김윤철 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.4

        The purpose of this study was to evaluate the shearbond strength and resin-dentin interface of three different dentinal bonding systems in primary and permanent teeth. Thirty extracted human primary molars and premolars, which were non-carious and free of obvious defect, were selected for this study. All specimens were divided into six groups with two groups allocated for each of the three dentinal bonding system(All-bond 2, Scotchbond Multi-Purpose, Gluma bonding system). After completion of bonding composite to dentin using each tested dentin bonding system, bond strength measurement and histological observation were performed. The results are as follows; 1. All-bond 2 and Scotchbond Multi-Purpose, A good quality hybrid layer was identified, the morphology of which could be equated with the zone of H-E and Brown-Brenn staining. In Gluma bonding system, hybrid layer was very thin, and separated from the solid polymer. 2. All-bond 2 had the highest mean shearbond strength, followed by Scotchbond Multi-Pur-pose and Gluma bonding system in both primary and permanent teeth. There was no statistically significant difference between All-bond 2 and Scotchbond Multi-Purpose. Statistically significant difference could be found between Gluma bonding system and the other two groups(p<0.05). 3. The fracture patterns observed were mainly the mixture of adhesive failure and dentin dettachment pattern in All-bond 2 and Scotchbond Multi-Purpose while adhesive failure prevailed in Gluma bonding system.

      • 도시화에 따른 지표수 관리기법

        최윤영,정광옥,지홍기 영남대학교 지역발전연구소 1997 새마을지역개발연구 Vol.20 No.-

        This study is aimed at the development of management of surface water in the urban environment. In the civilization process of riverside, natural and humane environment has changed continually, and there are more frequent changes in flux and quantity of surface flow in civilized riverside than in natural riverside. Civilization concerned with the concentration of population and activity and expanding the range of urban area changed natural environment, and humane activity in urban area caused appearance of new hydrologic cycle system. This study defined the concept of urban environment and the role of river and investigated the change of natural environment caused by the civilization of urban area, the change of recharge from surface flow fluxing characteristics in urban river, and flux for suggesting the organization system of surface flow in urban river. To make the device which reasonably organize the surface water flow insurance in urban environment, this study systematically suggests the surface water flow management on flood-control, water-use and environmental aspect. To make the device which synthetically manage the surface water flow in urban river, this study suggests urban river synthetically management model which aims for harmony with nature which contains the concept of amenity, connecting with space, devotion to local for river development and preservation.

      • 耕耘實驗을 爲한 人工土壤의 物理的 特性에 關한 硏究

        金基大,許潤根,金滿秀,金聲來 충남대학교 농업과학연구소 1978 農業技術硏究報告 Vol.5 No.2

        For improvement and new design of tillage equipments, indoor test is very useful and more desirable than outdoor because the experiment of ourdoor is very difficult and its cost is expensive. This study was carried out to determine the physical properties of artificial soil suitable for the indoor test with the soil bin manufactured at the workshop of the Dept. of Agricultural Machinery Engineering. The artificial soil being studied was made with very similarity to the natural soil of the experimental plots of Chungnam National University, and it consist of 39.35 percent, by weight of bentonite and 48.10 percent of sand with 12.55 percent of SAE 10W oil. The results are summarized as follows: 1. Bulk density increased with increasing number of rolling, and its relationship could be expressed. y=1.073200+0.07080x-0.002263x^2 where, y=bulk density(g/㎤), x=number of rolling. These results could be explained that the effect of rolling velocity on the bulk density was not singnificant in the range of 4.5∼10.4 cm/sec. 2. The absolute soil hardness depended directly upon number of rolling, and their relationship could be expressed by the equation. y=37.74(0.64+0.17x-0.0054x^2)/(3.36-0.17x-0.0054x^2)^3. where, y=absolute soil hardness(kg/㎤), x=number of rolling. 3. Relationship between the bulk density and absolute soil hardness could be expressed by the equation; y=37.74(2.46 x-2.02)/(6.02-2.46x)^3. where, y=absolute soil hardness, x=bulk density. 4. The cohesion and the angle of internal friction of artificial soil were increased with increasing its bulk density. According to the cohesion and angle of internal friction, at the range of 1.60∼1.75(g/㎤) of bulk density, this artificial soil was similar with sandy loam of 29.5% moisture content of natural soil. 5. Sliding-fricfion coefficient of steel plate on the artificial soil was 0.3∼0.4 and rubber plate on it is 0.64∼0.72. Those values were very similar with those of natural soil being studies by many others.

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