In vitro hemorheological effects of parenteral agents used in peripheral arterial disease

Katalin Biro,Barbara Sandor,Andras Toth,Katalin Koltai,Judit Papp,Miklos Rabai,Kalman Toth,Gabor Kesmarky 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2

Peripheral arterial disease (PAD) is a frequent manifestation of systemic atherosclerosis. In PAD hemorheologicalparameters were defined as risk factors in a number of studies and several therapeutic agents weretried in these conditions. Our study aims to investigate and compare the in vitro hemorheological effectsof various drugs generally used in the parenteral treatment of intermittent claudication and critical limbischemia. Blood samples of healthy male volunteers were incubated with iloprost, alprostadil, pentoxifylline,sulodexide or pentosan polysulfate at calculated therapeutic serum concentration. Hematocrit(Hct) was determined by microhematocrit centrifuge. Plasma and apparent whole blood viscosities (WBV)were evaluated by capillary viscometer. Red blood cell aggregation was measured by LORCA (laserassistedoptical rotational cell analyzer) aggregometer, and LORCA ektacytometer was used for measuringerythrocyte deformability at 37°C. Iloprost, alprostadil, and pentoxifylline incubation did not have any significanteffect on plasma and apparent WBV. Elongation index increased in samples incubated with alprostadilat low shear stresses 0.95 and 0.53 Pa (p < 0.05). Sulodexide significantly improved WBV and Hct/WBV ratio (p < 0.05). Incubation with pentosan polysulfate resulted in higher WBV, lower Hct/WBV ratioand deterioration in the aggregation parameters (p < 0.05). Sulodexide may have beneficial effect on a macrorheologicalparameter; alprostadil may improve a microrheological parameter. Hemorheological alterationscould be important in PAD patients with hampered vasodilator capacity.

In vitro hemorheological effects of parenteral agents used in peripheral arterial disease

Biro, Katalin,Sandor, Barbara,Toth, Andras,Koltai, Katalin,Papp, Judit,Rabai, Miklos,Toth, Kalman,Kesmarky, Gabor 한국유변학회 2014 Korea-Australia rheology journal Vol.26 No.2

Peripheral arterial disease (PAD) is a frequent manifestation of systemic atherosclerosis. In PAD hemorheological parameters were defined as risk factors in a number of studies and several therapeutic agents were tried in these conditions. Our study aims to investigate and compare the in vitro hemorheological effects of various drugs generally used in the parenteral treatment of intermittent claudication and critical limb ischemia. Blood samples of healthy male volunteers were incubated with iloprost, alprostadil, pentoxifylline, sulodexide or pentosan polysulfate at calculated therapeutic serum concentration. Hematocrit (Hct) was determined by microhematocrit centrifuge. Plasma and apparent whole blood viscosities (WBV) were evaluated by capillary viscometer. Red blood cell aggregation was measured by LORCA (laserassisted optical rotational cell analyzer) aggregometer, and LORCA ektacytometer was used for measuring erythrocyte deformability at $37^{\circ}C$. Iloprost, alprostadil, and pentoxifylline incubation did not have any significant effect on plasma and apparent WBV. Elongation index increased in samples incubated with alprostadil at low shear stresses 0.95 and 0.53 Pa (p < 0.05). Sulodexide significantly improved WBV and Hct/WBV ratio (p < 0.05). Incubation with pentosan polysulfate resulted in higher WBV, lower Hct/WBV ratio and deterioration in the aggregation parameters (p < 0.05). Sulodexide may have beneficial effect on a macrorheological parameter; alprostadil may improve a microrheological parameter. Hemorheological alterations could be important in PAD patients with hampered vasodilator capacity.

Expectation of smart mentality and citizen participation in technology-driven cities

Katalin Feher 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.27 No.3

The purpose of the paper is to investigate the expectations of smart mentality and citizen participation in technology-driven cities. 150 mainstream trend reports, white papers, and research summaries are analyzed in one corpus as business, governmental, and university research cooperations. The changing trends of the related academic literature frame the study. Keyword statistics, word pairs, content networks, and correlation matrix reveal the expected citizen participation. The most referenced top ten cities and their strategies support the understanding of the smart mentality behind the participation. According to the findings, open data, communities, collective participation, socio-technical engagement, and empowerment are the most expected human factors. Anonymity, neighborhood-based implementations, and temporary human roles are underrepresented in the corpus, as well as the privacy concerns and ethical issues. However, the emerging AI technology and the interpretative metaphors with rainforest, team player, and public agora urge a focus also on these indicators with a contribution of citizen engagement. The paper provides governmental policymaking and the academic research of technology-driven cities with a citizen-centric and complex summary.

COMPARISON OF HOTEL CLASSIFICATION IN JAPAN AND KOREA

Katalin Cser,Yukihiko Oyanagi,Azuma Ohuchi 세계문화관광학회 2007 Conference Proceedings Vol.8 No.0

This paper examines two Asian countries, Japan and Korea and compares their hotel classification system. Many studies have been reported about classification schemes in general, but less research has been engaged with detailed analysis. This work aims to contribute to fill in the gap by comparing structures and characteristics of the two systems and analyzing the differences. This work further investigates high-class hotels in Hokkaido and studies whether they would meet the requirements for high-category hotels in Korea as well. This paper suggests that the results of this investigation would assist Korean tourists to make easier and faster decisions for hotels in Japan and to avoid disappointments and misperceptions in advance.

Efficient and Reliable in vitro Regeneration System for Rubus Species as the Basis of Genetic Engineering

Kalai Katalin,Meszaros Annamaria,Denes Ferenc,Zatyko Jozsef,Balazs Ervin The Korean Society of Plant Biotechnology 2005 Plant molecular biology and biotechnology research Vol.7 No.4

Factors affecting regeneration of different Rubus varieties (blackberry, raspberry and their hybrid) were examined and a reliable regeneration system was established. Media for stock plant maintenance were tested; different explants and media were investigated to find the best circumstances for the regeneration. The effect of the commonly used antibiotics was studied to determine the most suitable one for selection of the transformants. We found that both MS and LS media supplemented by $20\;gL^{-1}$ sucrose are suitable for the stock plant maintenance. The optimal hormone content for the stock plants is $0.125\;mgL^{-1}$ 6-benzylaminopurine (BAP) with $0.01\;mgL^{-1}$ indole-3- butyric acid (IBA). The highest regeneration rate was observed on medium containing MS salts with B5 vitamins complemented with glucose, sucrose, maltose, $10\;gL^{-1}$ each, supplemented with benzylaminopurine riboside (BAR) ($2\;mgL^{-1}$) and indole-3-acetic acid (IAA) ($0.1\;mgL^{-1}$). The regenerated shoots appeared directly from the cut edges, without callus phase. Hygromycin and geneticin proved to be good selection agents for the Rubus explants, but due to their severe effect on the tissues we propose to use marker-free constructions for the transformation.

A Multi-Disciplinary Examination of Psycho-Physiological Performance Among Youth and Junior Ball Sport Athletes: A Systematic Review

József Márton Pucsok(József Márton Pucsok ),Andrea Lentene Puskas(Andrea Lentene Puskas ),Katalin Varga(Katalin Varga ),Gabriella Perenyi(Gabriella Perenyi ),Eva Bacsne Baba(Eva Bacsne Baba ),Laszlo B 사피엔시아 2018 Exercise Medicine Vol.2 No.-

Objectives: The primary purpose of our review was to systematically review the evolution of psycho-physiological performance analysis. Our secondary aim was to investigate the role of specific, multi-disciplinary performance indicators to identify future talents in the sport of soccer, handball and basketball. Methods: A review protocol was set up in order to avoid individual bias and ensure an efficient searching prodedure. This enabled a search strategy to define which literature was to be included or excluded from our research. Certain inclusion criteria were identified, before performing a search using three electronic databases (Web of Science, ScienceDirect, and Google Scholar) and reference lists for English-language articles, published from the year 1980 till 2017. Results: The comprehensive search yielded 82 documents to be relevant to our purpose of the study, according to our inclusion criteria criteria, 58 were fully-reviewed and referred to in our study. As we previously expected, the review of related literature resulted investigations involving mostly soccer and basketball players, studies conducted on handball players are significantly fewer. The majority of those studies examined physical performance characteristics via various field test. Conclusions: We concluded that further analysis is necessary to identify relevant psycho-physiological performance indicators, in order to properly enhance sports performance in the younger athlete population and in general too. Vienna Test System protocols may offer a great potential to provide valuable information for athletes and their coaches to enhance athletic performance. Future research should focus on specifically identify Vienna Test System test protocols that may be linked to each particular sport.

미국 패션 전문 일간지 WWD USA에 나타난 한국 패션산업에 대한 부정적 기사 분석

이유리,( Katalin Medvedev ),( Patricia Hunt Hurst ),최윤정 한국의류학회 2009 한국의류학회 학술대회논문집 Vol.2009 No.-

Apocrine Encapsulated Papillary Carcinoma of the Breast: The First Reported Case with an Infiltrative Component

Bence Kővári,Katalin Ormándi,Zsolt Simonka,András Vörös,Gábor Cserni 한국유방암학회 2018 Journal of breast cancer Vol.21 No.2

Apocrine encapsulated papillary carcinoma (EPC) of the breast is a rare neoplasm, and only 10 cases have been reported in the literature to date. Although EPC by definition lacks a peripheral myoepithelial layer, all previously published apocrine EPC cases were clinically indolent and lacked a conventional invasive component. Herein, we report the 11th case of apocrine EPC, which had a conventional invasive carcinoma component and provides evidence of the malignant potential of this entity. We postulate that apocrine EPC is most likely a morphological variant of conventional EPC, with the same unpredictable malignant potential as non-apocrine cases.

Antifungal Activity of Extracellular Hydrolases Produced by Autolysing Aspergillus nidulans Cultures

Melinda Szilágyi,Fruzsina Anton,Katalin Forgács,유재혁,István Pócsi,Tamás Emri 한국미생물학회 2012 The journal of microbiology Vol.50 No.5

Carbon-starving Aspergillus nidulans cultures produce high activities of versatile hydrolytic enzymes and, among these,ChiB endochitinase and EngA β-1,3-endoglucanase showed significant antifungal activity against various fungal species. Double deletion of engA and chiB diminished the antifungal activity of the fermentation broths and increased conidiogenesis and long-term viability of A. nidulans, but decreased the growth rate on culture media containing weak carbon sources. Production of ChiB and EngA can influence fungal communities either directly due to their antifungal properties or indirectly through their effects on vegetative growth. Our data suggest saprophytic fungi as promising future candidates to develop novel biocontrol technologies.

Early Return to Play After Anterior Cruciate Ligament Reconstruction: Is It Worth the Risk?

László Török,Péter Jávor,Katalin Török,Ferenc Rárosi,Petra Hartmann 대한재활의학회 2022 Annals of Rehabilitation Medicine Vol.46 No.2

Objective To compare the outcomes of a 6-month-long accelerated rehabilitation with a 12-month-long rehabilitation. There is no consensus on the optimal duration of rehabilitation after anterior cruciate ligament reconstruction (ACLR). Trends in the past decades have shifted towards accelerated programs, often resulting in a return to play (RTP) at 4–6 months, postoperatively. However, longer rehabilitation cycles have recently experienced renaissance due to a greater understanding of graft remodeling. Methods Adult athletes who underwent ACLR between 2015 and 2018 by the same surgeon were included and followed-up prospectively for 24 months. Participants were allocated into two groups based on their RTP (6 months vs. 12 months) and compared with graft elongation, reoperation rate, and sports career (quit or continue) outcomes. Results Fifty-four patients underwent accelerated rehabilitation and 92 completed conventional rehabilitation. The accelerated rehabilitation was significantly associated with graft elongation—the accelerated rehabilitation group (n=9) and the conventional rehabilitation group (n=0), p<0.001—and need for reoperation—the accelerated rehabilitation group (n=5) and the conventional rehabilitation group (n=1), p=0.026. Although the relationship between rehabilitation time and quitting competitive sports did not reach significance at 0.05 level (p=0.063), it was significant when p<0.1, thereby showing a clear trend. Conclusion Accelerated rehabilitation increased graft elongation risk. Knee laxity ≥3 mm measured at 6 months after ACLR should be accompanied by RTP time frame re-evaluation. Arthrometry checkups or routine magnetic resonance imaging shortly after RTP may be considered in cases of accelerated rehabilitation.