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      • 노르웨이의 저출산 현상 및 정책 시사점

        트루데라페고르드 ( Lappegard¸ Trude ),악셀페테르크리스텐센 ( Kristensen¸ Axel Peter ) 한국보건사회연구원 2023 국제사회보장리뷰 Vol.26 No.-

        지난 5년간 노르웨이의 출산율은 해마다 사상 최저치를 기록했다. 노르웨이의 노동시장 여건은 과거나 지금이나 상당히 양호한 편이다. 아울러 정부는 출산 가구를 대상으로 관대한 정책을 시행해 왔다. 따라서 출산율 저하의 원인을 가족정책 외에 다른 곳에서 찾아야 한다. ‘불확실성’이라는 측면에서 보면, 불확실한 경제적 상황에 처해 있거나 미래를 경제적으로 불확실한 것으로 여기는 사람들은 자녀 갖기를 더 주저할 수 있다. 이 글에서는 사람들의 선호도 변화 가능성(자녀를 갖는 것 이외의 활동에 더 높은 우선순위를 부여할 수 있는), 출산 궤적(fertility trajectory)에서 남성이 담당하는 역할, 출산과 관련된 사회적 불평등의 변화가 미치는 영향 등을 미래의 출산 동향(fertility trend)과 관련지어 논의한다. For the last five years, fertility levels in Norway have reached new historical lows every year. The conditions in the Norwegian labor market have been and still are quite good. At the same time, the government offers generous policies when people have children, meaning we must search elsewhere for explanations for the decline in fertility than family policies. According to the uncertainty perspective, people in an uncertain economic situation or people viewing the future as more economically uncertain, may be more hesitant to have children. We argue that future fertility trends must be considered in relation to possible changing preferences where people may give higher priorities to other activities than having children, the role of men’s fertility trajectories and the consequences of a shift in the social inequality in fertility.

      • EMBEDDED PROTOSTARS IN THE DUST, ICE, AND GAS IN TIME (DIGIT)<i>HERSCHEL</i>KEY PROGRAM: CONTINUUM SEDs, AND AN INVENTORY OF CHARACTERISTIC FAR-INFRARED LINES FROM PACS SPECTROSCOPY

        Green, Joel D.,Evans II, Neal J.,Jørgensen, Jes K.,Herczeg, Gregory J.,Kristensen, Lars E.,Lee, Jeong-Eun,Dionatos, Odysseas,Yildiz, Umut A.,Salyk, Colette,Meeus, Gwendolyn,Bouwman, Jeroen,Visser, Ruu IOP Publishing 2013 The Astrophysical journal Vol.770 No.2

        <P>We present 50-210 mu m spectral scans of 30 Class 0/I protostellar sources, obtained with Herschel-PACS, and 0.5-1000 mu m spectral energy distributions, as part of the Dust, Ice, and Gas in Time Key Program. Some sources exhibit up to 75 H2O lines ranging in excitation energy from 100 to 2000 K, 12 transitions of OH, and CO rotational lines ranging from J = 14 -> 13 up to J = 40 -> 39. [O I] is detected in all but one source in the entire sample; among the sources with detectable [O I] are two very low luminosity objects. The mean 63/145 mu m [O I] flux ratio is 17.2 +/- 9.2. The [O I] 63 mu m line correlates with L-bol, but not with the time-averaged outflow rate derived from low-J CO maps. [C II] emission is in general not local to the source. The sample L-bol increased by 1.25 (1.06) and T-bol decreased to 0.96 (0.96) of mean (median) values with the inclusion of the Herschel data. Most CO rotational diagrams are characterized by two optically thin components (< N > = ( 0.70 +/- 1.12) x 10(49) total particles). N-CO correlates strongly with L-bol, but neither T-rot nor N-CO(warm)/N-CO(hot) correlates with L-bol, suggesting that the total excited gas is related to the current source luminosity, but that the excitation is primarily determined by the physics of the interaction (e.g., UV-heating/shocks). Rotational temperatures for H2O (< T-rot > = 194 +/- 85 K) and OH (< T-rot > = 183 +/- 117 K) are generally lower than for CO, and much of the scatter in the observations about the best fit is attributed to differences in excitation conditions and optical depths among the detected lines.</P>

      • SCISCIESCOPUS

        CO in Protostars (COPS): <i>Herschel</i>-SPIRE Spectroscopy of Embedded Protostars

        Yang, Yao-Lun,Green, Joel D.,Evans II, Neal J.,Lee, Jeong-Eun,Jørgensen, Jes K.,Kristensen, Lars E.,Mottram, Joseph C.,Herczeg, Gregory,Karska, Agata,Dionatos, Odysseas,Bergin, Edwin A.,Bouwman, Jeroe American Astronomical Society 2018 The Astrophysical journal Vol.860 No.2

        <P>We present full spectral scans from 200 to 670. mu m of 26 Class 0+I protostellar sources obtained with Herschel-SPIRE as part of the 'COPS-SPIRE' Open Time program, complementary to the DIGIT and WISH Key Programs. Based on our nearly continuous, line-free spectra from 200 to 670. mu m, the calculated bolometric luminosities (L-bol) increase by 50%. on average, and the bolometric temperatures (T-bol) decrease by 10%. on average, in comparison with the measurements without Herschel. Fifteen protostars have the same class using Tbol and L-bol/L-smm. We identify rotational transitions of CO lines from J = 4 -> 3to J = 13 -> 12, along with emission lines of (CO)-C-13, HCO+, H2O, and [C I]. The ratios of (CO)-C-12 to (CO)-C-13 indicate that (CO)-C-12 emission remains optically thick for J(up) < 13. We fit up to four components of temperature from the rotational diagram with flexible break points to separate the components. The distribution of rotational temperatures shows a primary population around 100 K with a secondary population at similar to 350 K. We quantify the correlations of each line pair found in our data set and find that the strength of the correlation of CO lines decreases as the difference between J levels between two CO lines increases. The multiple origins of CO emission previously revealed by velocity-resolved profiles are consistent with this smooth distribution if each physical component contributes to a wide range of CO lines with significant overlap in the CO ladder. We investigate the spatial extent of CO emission and find that the morphology is more centrally peaked and less bipolar at high-J lines. We find the CO emission observed with SPIRE related to outflows, which consists of two components, the entrained gas and shocked gas, as revealed by our rotational diagram analysis, as well as the studies with velocity-resolved CO emission.</P>

      • KCI등재

        The Third Version of the Copenhagen Psychosocial Questionnaire

        Hermann Burr,Hanne Berthelsen,Salvador Moncada,Matthias Nübling,Emilie Dupret,Yucel Demiral,John Oudyk,Tage S. Kristensen,Clara Llorens,Albert Navarro,Hans-Joachim Lincke,Christine Bocéréan,Ceyda Saha 한국산업안전보건공단 산업안전보건연구원 2019 Safety and health at work Vol.10 No.4

        Introduction: A new third version of the Copenhagen Psychosocial Questionnaire (COPSOQ III) has been developed in response to trends in working life, theoretical concepts, and international experience. A key component of the COPSOQ III is a defined set of mandatory core items to be included in national short, middle, and long versions of the questionnaire. The aim of the present article is to present and test the reliability of the new international middle version of the COPSOQ III. Methods: The questionnaire was tested among 23,361 employees during 2016e2017 in Canada, Spain, France, Germany, Sweden, and Turkey. A total of 26 dimensions (measured through scales or single items) of the middle version and two from the long version were tested. Psychometric properties of the dimensions were assessed regarding reliability (Cronbach a), ceiling and floor effects (fractions with extreme answers), and distinctiveness (correlations with other dimensions). Results: Most international middle dimensions had satisfactory reliability in most countries, though some ceiling and floor effects were present. Dimensions with missing values were rare. Most dimensions had low to medium intercorrelations. Conclusions: The COPSOQ III offers reliable and distinct measures of a wide range of psychosocial dimensions of modern working life in different countries; although a few measures could be improved. Future testing should focus on validation of the COPSOQ items and dimensions using both qualitative and quantitative approaches. Such investigations would enhance the basis for recommendations using the COPSOQ III.

      • SCISCIESCOPUS
      • SCOPUSKCI등재

        The Third Version of the Copenhagen Psychosocial Questionnaire

        Burr, Hermann,Berthelsen, Hanne,Moncada, Salvador,Nubling, Matthias,Dupret, Emilie,Demiral, Yucel,Oudyk, John,Kristensen, Tage S.,Llorens, Clara,Navarro, Albert,Lincke, Hans-Joachim,Bocerean, Christin Occupational Safety and Health Research Institute 2019 Safety and health at work Vol.10 No.4

        Introduction: A new third version of the Copenhagen Psychosocial Questionnaire (COPSOQ III) has been developed in response to trends in working life, theoretical concepts, and international experience. A key component of the COPSOQ III is a defined set of mandatory core items to be included in national short, middle, and long versions of the questionnaire. The aim of the present article is to present and test the reliability of the new international middle version of the COPSOQ III. Methods: The questionnaire was tested among 23,361 employees during 2016-2017 in Canada, Spain, France, Germany, Sweden, and Turkey. A total of 26 dimensions (measured through scales or single items) of the middle version and two from the long version were tested. Psychometric properties of the dimensions were assessed regarding reliability (Cronbach α), ceiling and floor effects (fractions with extreme answers), and distinctiveness (correlations with other dimensions). Results: Most international middle dimensions had satisfactory reliability in most countries, though some ceiling and floor effects were present. Dimensions with missing values were rare. Most dimensions had low to medium intercorrelations. Conclusions: The COPSOQ III offers reliable and distinct measures of a wide range of psychosocial dimensions of modern working life in different countries; although a few measures could be improved. Future testing should focus on validation of the COPSOQ items and dimensions using both qualitative and quantitative approaches. Such investigations would enhance the basis for recommendations using the COPSOQ III.

      • Assessment of variation in immunosuppressive pathway genes reveals <i>TGFBR2</i> to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

        Lei, Jieping,Rudolph, Anja,Moysich, Kirsten B,Rafiq, Sajjad,Behrens, Sabine,Goode, Ellen L,Pharoah, Paul PD,Seibold, Petra,Fasching, Peter A,Andrulis, Irene L,Kristensen, Vessela N,Couch, Fergus J,Ham BioMed Central 2015 Breast cancer research Vol.17 No.-

        <P><B>Introduction</B></P><P>Tumor lymphocyte infiltration is associated with clinical response to chemotherapy in estrogen receptor (ER) negative breast cancer. To identify variants in immunosuppressive pathway genes associated with prognosis after adjuvant chemotherapy for ER-negative patients, we studied stage I-III invasive breast cancer patients of European ancestry, including 9,334 ER-positive (3,151 treated with chemotherapy) and 2,334 ER-negative patients (1,499 treated with chemotherapy).</P><P><B>Methods</B></P><P>We pooled data from sixteen studies from the Breast Cancer Association Consortium (BCAC), and employed two independent studies for replications. Overall 3,610 single nucleotide polymorphisms (SNPs) in 133 genes were genotyped as part of the Collaborative Oncological Gene-environment Study, in which phenotype and clinical data were collected and harmonized. Multivariable Cox proportional hazard regression was used to assess genetic associations with overall survival (OS) and breast cancer-specific survival (BCSS). Heterogeneity according to chemotherapy or ER status was evaluated with the log-likelihood ratio test.</P><P><B>Results</B></P><P>Three independent SNPs in <I>TGFBR2</I> and <I>IL12B</I> were associated with OS (<I>P</I> <10<SUP>−3</SUP>) solely in ER-negative patients after chemotherapy (267 events). Poorer OS associated with <I>TGFBR2</I> rs1367610 (G > C) (per allele hazard ratio (HR) 1.54 (95% confidence interval (CI) 1.22 to 1.95), <I>P</I> = 3.08 × 10<SUP>−4</SUP>) was not found in ER-negative patients without chemotherapy or ER-positive patients with chemotherapy (<I>P</I> for interaction <10<SUP>−3</SUP>). Two SNPs in <I>IL12B</I> (r<SUP>2</SUP> = 0.20) showed different associations with ER-negative disease after chemotherapy: rs2546892 (G > A) with poorer OS (HR 1.50 (95% CI 1.21 to 1.86), <I>P</I> = 1.81 × 10<SUP>−4</SUP>), and rs2853694 (A > C) with improved OS (HR 0.73 (95% CI 0.61 to 0.87), <I>P</I> = 3.67 × 10<SUP>−4</SUP>). Similar associations were observed with BCSS. Association with <I>TGFBR2</I> rs1367610 but not <I>IL12B</I> variants replicated using BCAC Asian samples and the independent Prospective Study of Outcomes in Sporadic versus Hereditary Breast Cancer Study and yielded a combined HR of 1.57 ((95% CI 1.28 to 1.94), <I>P</I> = 2.05 × 10<SUP>−5</SUP>) without study heterogeneity.</P><P><B>Conclusions</B></P><P><I>TGFBR2</I> variants may have prognostic and predictive value in ER-negative breast cancer patients treated with adjuvant chemotherapy. Our findings provide further insights into the development of immunotherapeutic targets for ER-negative breast cancer.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1186/s13058-015-0522-2) contains supplementary material, which is available to authorized users.</P>

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