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Bilateral Optic Disc Drusen Mimicking Papilledema
Alparslan Şahin,Abdullah Kürşat Cingü,Şeyhmus Ari,Yasin Çinar,İhsan Çaça 대한신경과학회 2012 Journal of Clinical Neurology Vol.8 No.2
Background Optic disc drusen, which are calcified deposits that form anterior to the lamina cribrosa in the optic nerve, may mimic papilledema. Case Report We report herein three cases referred to us with suspicion of disc swelling and papilledema. Following ophthalmologic evaluation with B-scan ultrasound, red-free fundus photography, and computed tomography, the diagnosis of papilledema was excluded in all cases and optic disc drusen was diagnosed. Conclusions Clinical suspicion of optic disc drusen in cases presenting with swelling of the optic nerve head is important in order to avoid unnecessary interventions and anxiety. The reported cases highlight the commonly encountered clinical presentations and the practical aspects of diagnosis and management of optic disc drusen.
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Nuray Bayar Muluk,Osman Kürşat Arıkan 대한이비인후과학회 2013 Clinical and Experimental Otorhinolaryngology Vol.6 No.3
Objectives. The aim of this study is to investigate the role of platelet-derived growth factor (PDGF) in the pathogenesis of sinonasal polyps. Methods. Study group (groups 1-3) consisted of nasal polyp samples of patients with sinonasal polyps and the control group consisted of inferior turbinate samples of patients without nasal polyp. In group 1, 14 specimens from ethmoid sinus; in group 2, 10 specimens from nasal cavity; in group 3, 10 specimens from maxillary sinus; and in group 4 (control), 9 specimens from inferior turbinate were included. By immunohistochemical staining technique, the PDGF positivity index (PI) in mucosal layers and in the inflammatory cells were assessed at the epithelium (EP), subepithelial layer of lamina propria (SE), and deep paraglandular layer of the mucosa (D). Results. Polymorphonuclear cell (PMNC)-percentage (%) values of ethmoid and maxillary sinus, and the PDGF PI from all cells of ethmoid sinus and nasal cavity were significantly higher than those of the control group. As mononuclear cell-% (MNC-%) increased, the PDGF_EP_basal PI, PDGF_SE_endothelial PI, and PDGF_D_endothelial PI decreased. As PMNC-PDGF PI increased, the PDGF_D_perivascular PI decreased and PDGF_D_endothelial PI increased. As PDGF-MNC PI increased, the PDGF_EP_apical PI, PDGF_SE_endothelial PI, and PDGF_D_endothelial PI decreased. As PDGF-all cells (PMNCs, MNCs, and fibroblasts) PI increased, the PDGF_EP_basal PI and PDGF_D_endothelial PI decreased, and the PDGF_D_perivascular PI increased. Conclusion. We concluded that the PDGF systems play important roles in polyp pathogenesis. Fibroblast-derived PDGF may be more important than MNC-derived PDGF in polyp developing process. Increased perivascular-PDGF-PI in deep layers of the mucosa may result in sinonasal polyp formation by causing an increase in vascular permeability and extracellular edema, and thus promoting migration of inflammatory cells to extracellular area. Tissue oxygenization may be important for the initiation of PDGF release system. Because of this reason, nasal obstruction should be medically treated earlier, and, if necessary, by surgical approaches.
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Cranially-based nasolabial flaps for the reconstruction of nasal surgical defects
Hakan Kerem,Ulaş Bali,Erhan Sönmez,Mustafa Kürşat Evrenos 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.2
Background Cranially-based nasolabial flaps are a good alternative for the reconstruction of nasal defects. Methods A cranially-based nasolabial flap was used in 18 patients to reconstruct defects of the nose from 2010 to 2016, and the long-term results are presented in this report. Results Fifteen of the flaps completely survived. All the patients had a bulky appearance, but they did not want to undergo a second operation for cosmesis. The dissection of the flap took approximately 20 minutes, and the total operation lasted for 1 hour. The patients were hospitalized for 1–7 days, and the postoperative follow-up period was 1–28 months (mean, 17 months). Conclusions The cranially-based nasolabial flap possesses all the advantages of the traditional forehead flap, and can safely be used in selected cases.
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Özpınar Ali,Yazmış Efecan,Ali Baboo,Şahin Ali Kürşat 한국곤충학회 2020 Entomological Research Vol.50 No.12
This study has been carried out in the years of 2016–2017 to determine biological parameters of Capsodes infuscatus Brulle (Hemiptera: Miridae) on asphodel (Asphodelus aestivus Broth.) in the pastures of Canakkale, Turkey. In order to determine the population fluctuation of C. infuscatus, counting was done twice in a week on leaves, stems and flowers of plants in two different locations in the pasture. It was determined that the C. infuscatus aestivates in dried asphodel stalks as eggs. The first nymphal stages can be seen at the end of February, while adult population ends at the end of May. It was observed that both the nymphal and adult stages of C. infuscatus were feeding together on A. aestivus from March to May. In 2016, an average of 7.86%, 57.26%, 8.72% and 34.12% C. infuscatus individuals were recorded on plant, leaves, stems and flowers, respectively. In 2017, an average of 22.08%, 67.5%, 15.0% and 17.56% C. infuscatusindividuals were recorded on plant, leaves, stems and flowers, respectively. The mortality rates of C. infuscatus nymphal stages were 94.76% in grazing area and 95.77% in non‐grazing area. We concluded that C. infuscatus has potential for the biological control of A. aestivus.
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