Mahalanobis Taguchi System을 이용한 자동차 브레이크 성능 만족도를 고려한 설계조건 선정에 관한 연구

홍정의(Jung-Eui Hong),권홍규(Hong-Kyu Kwon) 한국산업경영시스템학회 2007 한국산업경영시스템학회지 Vol.30 No.1

  Mahalanobis Taguchi-System (MTS) is a pattern information technology, which has been used in different diagnostic applications to make quantitative decisions by constructing a multivariate system using data analytic methods without any assumption regarding statistical distribution. MTS performs Taguchi’s fractional factorial design based on the Mahalanobis distance as a performance metric. In this work, MTS used for analyzing automotive brake feeling system, which measured as a brake feel index (BFI) from 9 attributes. The automobile which has a good BFI score treated as a normal group for constructing Mahalanobis space. The results of this research show that two attributes (Pre load & Max deceleration) have a minus gain value and can be removed from further analysis. The difference of MD value between using all 9 attributes and just using significant attribute compared.

Streptococcus dysgalactiae로부터 분리된 히알루론산과 황화된 유도체의 구조와 항염증 활성

홍창일(Chang-Il Hong),정의길(Eui-Gil Jung),한국일(Kook-Il Han),김용현(Yong Hyun Kim),이성희(Sung Hee Lee),이홍섭(Hong Sub Lee),한만덕(Man-Deuk Han) 한국생명과학회 2016 생명과학회지 Vol.26 No.5

히알루론산(HA, Hyaluronic acid)은 β-1, 3-N-acetyl glucosamine과 β-1, 4-glucuronic acid가 반복된 선형 폴리머 고분자로서 생물학적 활성 및 생체친화성 특성 때문에 의약 및 약학분야에서 중요한 분자로 여겨지고 있다. 본 연구는 HA을 S. dysgalactiae으로 얻고, 화학적 방법을 통해 황화된 히알루론산(S-HA, Sulfated hyaluronic acid)유도체를 합성하여 그 구조와 항염증 활성을 비교하였다. HA의 생산은 S. dysgalactiae를 5 l 생물반응기를 이용하여 대량 배양하여 수용성 히알루론산(HA-WS, water soluble hyaluronic acid)과 비수용성 히알루론산(HA-WI, water insoluble hyaluronic acid)을 분리 정제하였다. 특히 HA-WI를 황화시켜 황화된 히알루론산(S-HA) 유도체를 합성하였으며, 그 수율은 90%로 나타났다. 합성된 S-HA의 구조를 FT-IR 및 ¹H/<SUP>13</SUP>C-NMR를 통해 S. dysgalactiae 로부터 생산된 표준 HA, HA-WS 및 HA-WI와 비교 분석한 결과, 황으로 치환된 양상을 확인하였다. 또한, S-HA의 항염증 활성을 RAW 264.7 대식세포를 통해 확인한 결과, S-HA는 천연 형태의 HA (HA, HA-WS)보다 nitric oxide (NO)와 COX-2 및 PGE₂ 유전자 발현이 유의하게 낮게 발현되었다. 염증 매개 cytokine인 TNF-α (<80 pg/ml) 및 IL-6 (<100 pg/ml)의 생성도 S-HA가 천연 HA보다 낮은 수준으로 정량되었다. 이 같은 결과에서 황화된 S-HA은 천연 히알루론산보다 용해성이 우수하고 염증관련 사이토카인의 생성 억제를 통해 항염증 효과를 나타내므로 염증치료제, 성형 및 생체 적용 약물전달 소재로 그 활용이 기대된다. Hyaluronic acid (HA) is an important macromolecule in medical and pharmaceutical fields. HA is a natural and linear polymer composed of repeating disaccharide units of β-1, 3-N-acetyl glucosamine and β-1, 4-glucuronic acid. This work aimed to confirm the structural characteristics and anti-inflammatory activities of HA and its chemically sulfated-HA. HA was produced from a fed-batch fermentation process using Streptococcus dysgalactiae in a 5 l bioreactor. HA was isolated water-soluble form (HA-WS) and water-insoluble form (HA-WI) from culture medium, and was obtained chemically sulfated-derivative (S-HA) that resulted in a 90% yield from HA-WI. The structural features of the sulfated- HA (S-HA) were investigated by FT-IR and ¹H-NMR spectroscopy. The FT-IR and NMR patterns revealed the similarity in both the FTIR spectrum as well as NMR spectrum of both reference standard and purified HA from S. dysgalactiae. The anti-inflammatory activities of HA and S-HA were examined on LPS-induced RAW 264.7 cells. S-HA was significantly inhibited production of pro-inflammatory mediators such as nitric oxide (NO) and PGE₂ and the gene levels of iNOS and COX-2, which are responsible for the production of NO and PGE₂, respectively. Furthermore, S-HA also suppressed the overproduction of pro-inflammatory cytokine TNF-α (<80 pg/ml) and IL-6 (<100 pg/ml) compared to that of HA-WI. The present study clearly demonstrates that HA-S exhibits anti-inflammatory activities in RAW 264.7 macrophage cells.

Mahalanobis Taguchi System을 이용한 척추질환 환자의 진단에 관한 연구

홍정의(Jung Eui Hong) 한국산업경영시스템학회 2012 한국산업경영시스템학회지 Vol.35 No.4

The Mahalanobis-Taguchi System is a diagnosis and predictive method for analyzing patterns in multivariate cases. The goal of this study is diagnosis of the spondylolisthesis from biomedical data that is derived from the shape and orientation of the pelvis and lumbar spine. The data set has six attributes including pelvic incidence, pelvic tilt, lumbar lordosis angle, sacral slope, pelvic radius and grade of spondylolisthesis and two class including normal and abnormal. From University of California at Irvine machine learning repository, 100 normal and 150 spondylolisthesis patient’s data were used for this study. Mahalanobis Taguchi System (MTS) application process and the diagnosis results were described in this paper.

AHP를 활용한 온라인 게임의 사용성 평가요인에 관한 연구

홍정의(Hong, Jung-Eui) 한국상품학회 2021 商品學硏究 Vol.39 No.3

본 연구의 목적은 양질의 온라인 게임 이용 가능성을 선정하기 위한 평가 기준을 수립하고 평가 요소에 대한 정량적 척도를 이용한 평가 모델을 제시하는 것이다. 본 연구는 온라인 게임의 사용성에 관한 연구로 한정되었으며, 공간적 범위는 한국에 거주하며 온라인 게임을 사용한 경험이 있는 20 ~ 30 대 사용자로 제한하였다. 설문 조사를 기반으로 AHP (Analytical Hierarchy Process) 기법을 사용하여 고객 피드백을 반영하기 위해 AHP 분석 프로그램 인 Expert Choice11.5가 사용하였다. 온라인 게임사용에 영향을 미치는 요소 (사회적 응집력, 도전적 재미, 감각적 재미 및 상호 작용)를 살펴보고 이러한 요소가 고객의 온라인 게임 사용성에 얼마나 영향을 미치는지 우선순위를 분석하였다. 또한 중대성 비교에 앞서 응답자의 응답의 일관성을 파악하기 위해 의사 결정 과정에서 발생할 수 있는 오류를 파악하기 위해 그룹 간 일관성 비율 (CR)을 비교분석하였다. 본 연구를 통해 온라인 게임에 대한 서비스 품질 평가 모델을 제시하고, 온라인 게임 서비스의 지속적인 품질관리를 위한 기본 정보를 제공하고 향후 다양한 서비스를 제공 할 수 있는 기회를 제공할 수 있을 것으로 판단된다. The purpose of this study is establish evaluation criteria to select the availablitiy of good quality online game and to present an evaluation model that uses quantitative scales for evaluation factors. This study was limited to those related to the usability of online games, and the spatial scope was limited to users in their 20s and 30s who live in Korea and have experience using online games. Based on the survey, Expert Choice11.5, an AHP analysis program, was used to reflect customer feedback using the Analytical Hierarchy Process (AHP) technique.We look at the factors that affect online game usage (social cohesion, challenging fun, sensory fun, and interactivity) and analyze the priorities of howmany these factors affect customers online game usability. In addition, the consistency ratio (CR) between groups was checked to identify possible errors in the decision-making process in order to identify the consistency of respondents responses prior to the materiality comparison. Through this study, the service quality evaluation model is presented for the online game, and the opportunity to provide basic information for continuous qualitymanagement of the online game service and providing various services in the futurewill be given.

전기로를 이용한 제강공정의 최적 스크랩 배합 비율 선정에 대한 연구

홍정의 ( Jung Eui Hong ) 대한설비관리학회 2012 대한설비관리학회지 Vol.17 No.4

In steel production, an electric arc furnace (EAF) is most commonly used to melt raw material in order to produce liquid steel. Scrap is the main raw material which differs in regard to the content of iron and of some chemical elements. The price of scrap depends on these attributes. In order to obtain the desired quality and quantity, each melting bath unit of steel has either its own material constraints or the constraints for electric arc furnace such as the capacity of EAF. In addition, the availability and transportation of scrap are also restricted because they need space. This research is to create an optimization model which minimizes the cost of raw material The running speed of the model is reasonably guaranteed by properly designing the combinatorial structure with branch and bound rules. Simulation results show significant improvement compared to the : the cost of scrap steel is reduced by 2 to 6% and the time of charging buckets is 2 to 10 minutes faster.

서포트 벡터 머신을 이용한 질병의 진단에 관한 연구

홍정의 ( Jung Eui Hong ) 대한설비관리학회 2014 대한설비관리학회지 Vol.19 No.2

Support Vector Machines (SVM) are supervised learning algorithms that analyze data and recognize patterns and used for classification and regression analysis. Specially, SVM is an linear classifier to perform in such a way as to minimize the generalization error. In this study, SVM apply to diagnosis breast cancer. Breast cancer test data have 9 test parameters 2 class and 683 patients. Randomly select some patients as a train data for SVM train and predict the other patient data. The diagnosis results are compared with both different train data size and different training parameters.

Electrochemical Performance of Li₄Ti₅O<SUB>12</SUB> Modified by Carbon on Surface as an Anode of Lithium Ion Batteries

Jung-Eui Hong(홍정의),Kyu-Sik Kim(김규식),Han-Jin Jeon(전한진),Kwang-Sun Ryu(류광선) 한국전지학회 2021 한국전지학회지 Vol.1 No.1

스피넬구조를 가진 Li₄Ti₅O12 (LTO) 물질은 이론용량 175 mAh/g을 가지며 리튬이온의 삽입과 탈리의 뛰어난 가역성을 가진다. 또한 충전 및 방전 동안 용량 변화가 적다는 장점이 있다. 그러나 LTO는 전기전도성이 낮다는 단점이 있어 광범위하고 실용적인 적용에서는 제한적이라는 단점이 있다. 탄소코팅은 일반적으로 쉬우며, 효과적이며 그 결과도 전해액과의 표면에서의 전기전도성을 개선시킬 수 있다. 또한 전기적 성능의 향상도 가능하다. 여기서 LTO 표면에 malic산(C₄H₆O₅)을 이용하여 표면을 개질하여 리튬이온전지에서 음극에 사용 가능한 LTO의 성능개선을 위한 연구를 실시하였다. 본 연구에서는 1 wt%의 malic산으로 표면을 개질한 LTO가 가장 우수한 용량과 성능 유지를 하는 것을 알 수 있었다. Li₄Ti₅O12 (LTO) material with spinel structure has a theoretical capacity of 175 mAh/g and has excellent reversibility of insertion and desorption of lithium ions. In addition, there is an advantage that there is little change in capacity during charging and discharging. However, LTO has a disadvantage in that it has low electrical conductivity and is therefore limited in a wide range of practical applications. Carbon coating is generally easy and effective, and the result can also improve the electrical conductivity at the surface with the electrolyte. In addition, it is possible to improve the electrical performance. Here, the LTO surface was modified using malic acid (C₄H₆O₅) to improve the performance of LTO, which can be used as a negative electrode in a lithium ion battery. In this study, it was found that the surface-modified LTO with 1 wt% malic acid maintained the best capacity and performance.

포스터 발표 : 우수 중수도 및 기타 ; 통합 바이오인포매틱스 도구를 이용한 대장균 DNA damage 반응 분석

홍정의 ( Jung Eui Hong ),안주명 ( Joo Myung Ahn ),김병찬 ( Byung Chan Kim ),구만복 ( Man Bock Gu ) 대한상하수도학회 2007 공동추계 학술발표회 논문집 Vol.2007 No.-

다중회귀분석과 Mahalanobis Distance 이상치 탐색방법을 이용한 고강도 콘크리트 강도 예측 모델 개발에 관한 연구

홍정의 ( Jung Eui Hong ) 대한설비관리학회 2011 대한설비관리학회지 Vol.16 No.2

High-performance concrete(HPC) is a new terminology used in concrete construction industry. Several studies have shown that concrete strength development is determined not only by the water-to-cement ratio but also influenced by the contents of other concrete ingredients. HPC is a highly complex material, so it is very difficult task to modeling its behavior. This research aimed to predict the compressive strength of HPC with multiple linear regression analysis. Mahalanobis Distance(MD) outlier detection method used for the purpose of detecting outlier and increase prediction ability of regression analysis. The detailed procedure of calculating Mahalanobis Distance (MD) is described. The effects of outlier compared with before and after at the multiple linear regression.

우수 중수도 및 기타 : 통합 바이오인포매틱스 도구를 이용한 대장균 DNA damage 반응 분석

홍정의 ( Jung Eui Hong ),안주명 ( Joo Myung Ahn ),김병찬 ( Byung Chan Kim ),구만복 ( Man Bock Gu ) 한국물환경학회 ( 구 한국수질보전학회 ) 2007 공동 추계학술발표회 Vol.2007 No.-