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      • KCI등재

        차집관로와 하수처리시설의 설치에 따른 도시하천의 수질변화 특성

        주연연(Juan Juan Zhou),임봉수(Bong Su Lim) 大韓環境工學會 2014 대한환경공학회지 Vol.36 No.12

        대전 3대하천을 대상으로 차집관로와 하수처리시설 증설로 인한 도시하천의 수질변화의 특성을 분석하였다. 지난 10년 동안 최고 수질에서 최저 수질의 차이가 가장 큰 하천지점은 하수처리시설 하류부인 갑천5(신구교) 지점이다. 반면에 최근 수질은 이 지점이 다른 지점보다 수질이 불량한 것은 하수처리시설의 방류수 영향이다. 하수처리시설 상류부에서는 대전천이 유기물질의 오염감소에서 다른 지점보다 비교적 양호한 지점인데 이는 차집관로의 유지관리 투자에 기인한 것으로 보인다. 최근 3대하천 수질은 하천수질기준치와 비교하였을 때 대부분 수질항목은 기준치 이내로 적합하였으나 상류지점인 대 전천, 유등천, 갑천3 지점의 총인은 기준치에 못 미치므로 하수처리시설 상류부가 하류부보다 차집관로의 유지관리가 더 필요하다. 하수처리시설의 방류수 수질이 하천 수질오염총량관리 지점의 목표수질에 악영향을 주기 쉬우므로 하수처리시설 유지관리의 효율성이 적극 요구된다. In this study, the characteristics of water quality change of the three streams in Daejeon were analyzed according to the expanded installation of interceptors and wastewater treatment plant (WTP). Gabcheon 5 (Singu Bridge) location showed the maximum difference of the highest and lowest concentrations in the last decade. However, the recent water quality of this location was worse than other locations, because of the impact of the effluent from the WTP. In the upstream of the WTP, the Daejeon stream was relatively better than the other locations in organic pollution reduction, and this was caused by the investment for the management of the interceptors in three streams of Daejeon. According to the water quality standard of the stream water quality, the recent water quality of the three streams in Daejeon was acceptable within them in the most of the water quality items, but because the total phosphorus concentration of the upstream such as Daejeon stream, Yudeng stream, Gabchen 3 location did not reach the standard values, a better management of the interceptor was required in the upstream of WTP than its downstream. The upstream of WTP also required a better management of the interceptor than the downstream. The operation and management of WTP was required a high efficiency because the water quality of the effluent from the WTP incurred an adverse effect to the target water quality in the location of the total water pollution load management system.

      • SCOPUS

        A Comparative Study of Local Features in Face-based Video Retrieval

        Zhou, Juan,Huang, Lan Korean Institute of Information Scientists and Eng 2017 Journal of Computing Science and Engineering Vol.11 No.1

        Face-based video retrieval has become an active and important branch of intelligent video analysis. Face profiling and matching is a fundamental step and is crucial to the effectiveness of video retrieval. Although many algorithms have been developed for processing static face images, their effectiveness in face-based video retrieval is still unknown, simply because videos have different resolutions, faces vary in scale, and different lighting conditions and angles are used. In this paper, we combined content-based and semantic-based image analysis techniques, and systematically evaluated four mainstream local features to represent face images in the video retrieval task: Harris operators, SIFT and SURF descriptors, and eigenfaces. Results of ten independent runs of 10-fold cross-validation on datasets consisting of TED (Technology Entertainment Design) talk videos showed the effectiveness of our approach, where the SIFT descriptors achieved an average F-score of 0.725 in video retrieval and thus were the most effective, while the SURF descriptors were computed in 0.3 seconds per image on average and were the most efficient in most cases.

      • KCI등재

        KIF11 Functions as an Oncogene and Is Associated with Poor Outcomes from Breast Cancer

        Juan Zhou,Wei-Rong Chen,Li-Chao Yang,Jun Wang,Jia-Yuan Sun,Wen-Wen Zhang,Zhen-Yu He,San-Gang Wu 대한암학회 2019 Cancer Research and Treatment Vol.51 No.3

        Purpose The study aimed to search and identify genes that were differentially expressed in breast cancer, and their roles in cancer growth and progression. Materials and Methods The Gene Expression Omnibus (Oncomine) and The Cancer Genome Atlas databases (https://cancergenome.nih.gov/) were screened for genes that were expressed differentially in breast cancer and were closely related to a poor prognosis. Gene expressions were verified by quantitative real-time polymerase chain reaction, and genes were knocked down by a lentivirus-based system. Cell growth and motility were evaluated and in vivo nude mice were used to confirm the in vitro roles of genes. Markers of epithelial-to-mesenchymal transition and the associations of KIF11 with the classical cancer signaling pathways were detected by Western blot. Results A series of genes expressed differentially in patients with breast cancer. The prognosis associated with high KIF11 expression was poor, and the expression of KIF11 increased significantly in high stage and malignant tumor cells. Inhibiting KIF11 expression in lentivirussuppressed cells revealed that KIF11 inhibition significantly reduced cell viability and colony formation, inhibited migration and invasion, but promoted apoptosis. The sizes and weights of KIF11-inhibited tumors in nude mice were significantly lower than in the negative controls. Western blot showed that E-cadherin in breast cancer was significantly upregulated in KIFinhibited cells and tumor tissues, whereas N-cadherin and vimentin were significantly downregulated. BT549 and MDA231 cells with KIF11 knockdown exhibited decreased ERK, AMPK, AKT, and CREB phosphorylation. Conclusion KIF11 acts as a potential oncogene that regulates the development and progression of breast cancer.

      • KCI등재

        Prey instar preference and functional responses of Mallada basalis (Walker) (Neuroptera: Chrysopidae) to different life stages of Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae)

        Zhou Juan,Li Zi-Yuan,Guan Ying-Xue,Pan Zhi-Ping,Chen Ke-Wei 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.4

        Prey instar preference and functional responses of 2- and 3-instar Mallada basalis (Walker) (Neuroptera: Chrysopidae) larvae to 1- to 3-instar Phenacoccus solenopsis Tinsley (Hemiptera: Pseudococcidae) nymphs and adults were assessed in laboratory. Results indicated that both 2- and 3-instar M. basalis larvae preferred young over old P. solenopsis nymphs and adults were the least preferred. The 3-instar M. basalis larvae preyed more adult P. solenopsis than 2-instar larvae. Mallada basalis exhibited type II functional responses to prey densities: An increase in prey density leads to an increase in consumed preys. Regardless of P. solenopsis stages, the number of preys consumed by the 3-instar M. basalis larvae was greater than that by the 2-instar larvae. Attack rates and handling times differed depending on prey and predator stage combinations. The highest attack rate (1.1874) and lowest handling time (0.0040 h) were observed for the 3-instar M. basalis larvae fed on the 1-instar P. solenopsis nymphs. Regardless of P. solenopsis stages, the attack rate of 3-instar M. basalis was greater than 2-instar, whereas the reverse held regarding handling time. The findings collectively indicated that 3-instar M. basalis larvae have greater potential than 2-instar as efficient biological control agent of P. solenopsis. In developing real world biological control programs, however, the 2-instar M. basalis may be released if necessary since the final efficacy of the predator is the summation of the 2- and 3-instar M. basalis.

      • SCOPUS

        A Comparative Study of Local Features in Face-based Video Retrieval

        Juan Zhou,Lan Huang 한국정보과학회 2017 Journal of Computing Science and Engineering Vol.11 No.1

        Face-based video retrieval has become an active and important branch of intelligent video analysis. Face profiling and matching is a fundamental step and is crucial to the effectiveness of video retrieval. Although many algorithms have been developed for processing static face images, their effectiveness in face-based video retrieval is still unknown, simply because videos have different resolutions, faces vary in scale, and different lighting conditions and angles are used. In this paper, we combined content-based and semantic-based image analysis techniques, and systematically evaluated four mainstream local features to represent face images in the video retrieval task: Harris operators, SIFT and SURF descriptors, and eigenfaces. Results of ten independent runs of 10-fold cross-validation on datasets consisting of TED (Technology Entertainment Design) talk videos showed the effectiveness of our approach, where the SIFT descriptors achieved an average F-score of 0.725 in video retrieval and thus were the most effective, while the SURF descriptors were computed in 0.3 seconds per image on average and were the most efficient in most cases.

      • KCI등재

        H∞ Filtering for a Class of Singular Time-delay Systems

        Juan Zhou,Yuanwei Lv,Bo Pang,Cuiping Xue 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.12

        This paper describes the H∞ filtering problem for a class of nonlinear singular time-delay systems. A sufficient condition for the existence of H∞ filter is given. Based on the Cayley-Hamilton Theorem and Lyapunov stability theory, the H∞ filter is designed such that the filtering error is asymptotically stable and satisfies the prescribed H∞ performance. In terms of linear matrix inequality, a sufficient condition for the solvability of the addressed problem is obtained. Finally, some numerical examples are employed to demonstrate the effectiveness of the proposed approaches.

      • KCI등재

        Dissipative Analysis for Nonlinear Singular Systems with Time-delay

        Juan Zhou,Qing-Ling Zhang,Yue Zhang,Bo Men 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.6

        This paper is concerned with the dissipative control problem for a class of nonlinear singular systemswith time-delay. The quadratic supply rate with coefficient matrix Q > 0 and Q 0 are both discussed. Basedon the Lyapunov stability theory, sufficient conditions are given to guarantee that the system is strictly dissipativevia linear matrix inequality technique. Then congruent transformation method and Schur complement lemma arerespectively used to determine corresponding proportional and derivative feedback controller for Q > 0 andQ 0. At last, two examples involve a practical example are given to verify the effectiveness of the method proposed inthis paper.

      • KCI등재

        Ovarian Ablation Using Goserelin Improves Survival of Premenopausal Patients with Stage II/III Hormone Receptor-Positive Breast Cancer without Chemotherapy-Induced Amenorrhea

        Juan Zhou,San-Gang Wu,Jun-Jie Wang,Jia-Yuan Sun,Fengyan Li,Qin Lin,Huan-Xin Lin,Zhen-Yu He 대한암학회 2015 Cancer Research and Treatment Vol.47 No.1

        Purpose The purpose of this study was to assess the value of ovarian ablation using goserelin inpremenopausal patients with stage II/III hormone receptor-positive breast cancer withoutchemotherapy-induced amenorrhea (CIA). Materials and MethodsWe retrospectively reviewed the data of breast patients treated between October 1999 andNovember 2007 without CIA. The Kaplan-Meier method was used for calculation of thesurvival rate. Log rank method and Cox regression analysis were used for univariate andmultivariate prognostic analysis. ResultsThe median follow-up period was 61 months. Initially, 353 patients remained without CIAafter chemotherapy and 98 among those who received goserelin and tamoxifen (TAM). Inunivariate analysis, goserelin improved locoregional recurrence-free survival (LRFS) (98.9%vs. 94.1%, p=0.041), distant metastasis-free survival (DMFS) (85.4% vs. 71.9%, p=0.006),disease-free survival (DFS) (85.4% vs. 71.6%, p=0.005), and overall survival (OS) (93.5%vs. 83.5%, p=0.010). In multivariate analysis, goserelin treatment was an independentfactor influencing DMFS (hazard ratio [HR], 1.603; 95% confidence interval [CI], 1.228 to2.092; p=0.001), DFS (HR, 1.606; 95% CI, 1.231 to 2.096; p=0.001), and OS (HR, 3.311;95% CI, 1.416 to 7.742; p=0.006). In addition, treatment with goserelin resulted in significantlyimproved LRFS (p=0.039), DMFS (p=0.043), DFS (p=0.036), and OS (p=0.010) inpatients aged < 40 years. In patients aged  40 years, goserelin only improved DMFS(p=0.028) and DFS (p=0.027). ConclusionOvarian ablation with goserelin plus TAM resulted in significantly improved therapeuticefficacy in premenopausal patients with stage II/III hormone receptor-positive breast cancerwithout CIA.

      • Prevalence and Clinical Profile of EGFR Mutation In Non-Small-Cell Lung Carcinoma Patients in Southwest China

        Zhou, Juan,Song, Xing-Bo,He, He,Zhou, Yi,Lu, Xiao-Jun,Ying, Bin-Wu Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3

        Aims: To investigate the distribution of epidermal growth factor receptor (EGFR) mutations, and explore any relationships with clinical characteristics in non-small-cell lung carcinoma (NSCLC) patients. Materials and Methods: EGFR mutations were assessed by ADx-ARMS in 261 NSCLC patients from West China Hospital of Sichuan University. Relationships between EGFR mutation and clinical characteristics were analyzed by SPSS. Results: The EGFR mutation rate was 48.7% (127/261), 19-del and L858R mutations occurred predominantly, accounting for 33.1% and 40.9%, respectively, in mutated cases. Moreover, 10.2% patients were found to carry double mutations. EGFR mutations occurred more frequently in women (57.5%) than in men (41.8%) (P=0.01), and were more frequent in non-smokers (61.2%) than in former or current smokers (31.2%) (P<0.00). In addition, they were more common in adenocarcinomas (52.8%) and adenosquamous carcinomas (42.8%) than in squamous cell carcinomas (14.8%) (p<0.00). However, only smoking history and pathological types, rather than gender, proved to be associated with EGFR mutations on multivariate logistic regression analysis. No significant differences in pathological stage and metastasis status were found between EGFR wild-type and mutated cases, although EGFR mutation type was related to pathological type (p=0.00) - 19-del, L858R and other mutation types respectively occurred in 34.2%, 42.5% and 23.3% of adenocarcinomas, but in 14.3%, 0% and 85.7% of non-adenocarcinomas. Conclusions: The EGFR mutation rate was 48.7% in NSCLCs in Southwest China, so that nearly 40% patients might benefit from targeted therapies. Smoking status and pathological types were independent predictors of EGFR mutation, while EGFR mutation type was related to only pathological type, rather than smoking status.

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