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As the use of laboratory animals has increased in Korea, the need for new facilities has also grown. Today, the increased risk of handling infectious microorganisms of animals could lead to an increase in contamination of the laboratory environment and personnel. The World Health Organization (WHO) has recognized that biosafety is an important international issue; in response, the organization published the third edition of the Laboratory Biosafety Manual, 2004. More recently, the Public Health Agency of Canada published its own biosafety document, the third edition of Laboratory Biosafety Guidelines, in 2004. Additionally, the U.S. Department of Health and Human Services published the fifth edition of its Biosafety in Microbiological and Biomedical Laboratories in 2007. The National Institutes of Health, the Korea Centers for Disease Control and Prevention (KCDC) updated its Guideline for Laboratory Biosafety, concerning biosafety facilities, in May 2007. We analyzed the A-BL facilities in Canada, Australia, Japan, and the U.S.A. to compare them with our circumstances here in Korea. The Laboratory Animal Research Center of Konkuk University (KULARC) has recently established the Animal Biosafety Level-3 facility (ABL3). To ensure whether the KULARC's A-BL3 facility was properly designed and built, we inspected it using a biosafety checklist to aid us in the process of uncovering latent defects in existing facilities, and we now believe that we have met the related guidelines. We are sure that this facility provides an excellent example to other institutions and organizations planning to build an A-BL3 facility.
At the Jangheung multipurpose dam, which is on the Tamjin River, a trapping and trucking operation was established to maintain continuous upstream migration of fish,. To facilitate fish gathering, installation of an effective fishing trap was required. In this study, we evaluated the fish trap, established at the Jangheung dam, using PIT (Passive Integrated Transponder) telemetry. A total of 254 individuals from 15 species were monitored. Among these tagged species, 36 individuals from 6 species (Carassius auratus, C. cuvieri, Zacco temminckii, Z. platypus, Pungtungia herzi, and Pseudobagrus koreanus) were detected; a 14.2% detection rate. C. auratus recorded the highest detection rate of 44.2% while P. herzi was 14.3%. Z. temminckii and Z. platypus showed relatively low detection, 5% and 7.7% respectively. Some of individuals from C. auratus and Z. platypus did not pass through the antenna at the first attempt but were continuously detected on multiple days. There were no statistical differences in body size (total length, standard length and body weight) of individuals that did or did not swim into the trap (Mann-Whitney U test, p>0.05). Fish mainly swam into the trap during outflow of water from the dam (Mann-Whitney U test, p<0.001) and showed a higher detection frequency in daytime than nighttime (Mann-Whitney U test, p<0.001). Thus, for fish movement into the trap, external factors such as outflow from dam and time of day have important roles. Based on detection rate, not all fishes showed upstream migration but represented selective migration. Consequently, the establishment of flexible outflow strategies that take into consideration ecological characteristics of fishes should required for improving the efficiency of fishway.