만성 호중구성 백혈병 1례

기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.

국내 콘크리트 기준의 발전 방향에 대한 고찰

심종성,최장환,문도영,박성재 漢陽大學校 工學技術硏究所 2002 工學技術論文集 Vol.11 No.-

유럽 각국의 규준을 통합한 유로 Code의 등장과 북미지역을 중심으로 한 기술통합의 흐름과 같은 Global Network화의 추세에 적극적으로 대처하고자 Asia Concrete Model Code(ACMC)의 제정이 제안되었다. 현재까지 ACMC 위원회는 LevelⅠ과 Level Ⅱ의 draft를 완성하였으며, Level Ⅲ에서는 국가/지역조건을 고려한 실제적인 지침을 준비하고 있는 단계이다. 따라서 본 연구에서는 각 시방들을 비교·분석하고 현재 제안된 ACMC Level Ⅲ Document 및 Perforomance Based Design과 관련된 문헌들을 고찰함으로써 국내현황에 적합한 ACMC Level Ⅲ Document의 작성방안을 제안하고자한다. Asian Concrete Model Code (ACMC) was proposed to cope with appearance of Euro-Code and a trend of Global Network such as a flow of the technique unification of North America. ACMC Committee has completed two drafts of LevelⅠ and LevelⅡ. Also, prectial specification considering national/regional condition is being prepared in draft of Level Ⅲ Document. On the study, each specification was analyzed and compared and a number of references were studied in order to propose ACMC Level Ⅲ Document considering domestic conditions.

척추경 나사못을 이용한 척추 유합술에서 고정범위에 따른 인접 추간판의 압축 거동 분석

안면환,안종철,이수호,정일섭,이춘열,이장우 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.2

요추부 척추에 기구를 시술한 유한요소 복합체 모델을 이용하여 제 4-5 요추간판에 대한 해석을 수행한 결과, 근육의 작용을 케이블과 케이블 가이드로써 단순화 모사한 follower 하중에서 수직하중인 경우보다 높은 압축력을 나타내어 더욱 안정함을 보였고 불안정성의 원인이 되는 전단력과 굽힘모멘트의 발생은 미미하였다. 장분절 고정에 의한 인접 분절에 전단력이 증가됨을 실험적으로 보였는데, 이는 장분절 고정이 퇴행성 변화 촉진에 기여할 것으로 추정된다. Background: Confirm the stability of intervertebral disc sustaining each fused lumbar spine cases, comparing vertical compression, A-P shear force and rotational moment on intervertebral disc of instrumented lumbar spine with simple vertical compression load and follower load using finite element analysis. Materials and Methods: We analyze the stability of intervertebral disc L4-5 supporting fused lumbar spine segments. After performing finite element modelling about L1-L5 lumbar vertebral column and L1-L4 each fusion level pedicle screw system for fused lumbar spine fine element model. Intervertebral discs with complex structure and mechanical properties was modeled using spring element that compensate stiffness and tube-to-tube contact element was employed to give follower load. Performing geometrical non-linear analysis. Results: The differences of intervertebral disc L4-5 behavior under the follower compression load in comparision with vertical compression load are as follows. Conclusion: As a result of finite element interpretation of interpretation of instrumented lumbar spine, the stability of L4-5 sustaining fused lumbar segment, the long level fused lumbar spine observed hing stability under follower load. This research method can be the basis tool of effects prediction for instrumentation, a invention of a more precious finite element interpretation model which consider the role of muscle around the spine is loaded.

Facial Feature Location Based On Level Set Method

오응군, 장종환 배재대학교 공학연구소 2013 공학논문집 Vol.15 No.1

We present an algorithm to locate facial features using level set method. It shows that the proposed method can efficiently find eyes, nose, and mouth etc. in the typical test images. Experimental results have shown that our algorithm produces well accurate location of facial features in several images.

중성자에 조사된 원자로 압력용기 재료의 Barkhausen 노이즈에 관한 연구

옥치일,김장환,박덕근,홍준화,이종규 韓國非破壞檢査學會 1998 한국비파괴검사학회지 Vol.18 No.6

원자로 압력용기 재료인 SA508 steel을 온도 70℃와 대기압하에서 최고 10 n/㎠까지 중성자를 조사시켜 조사량에 따른 자기이력곡선과 Barkhausen noise amplitude(BNA), Barkhausen noise energy(BNE) 및 미세경도 변화를 측정하여 이들 사이의 상관관계를 구하였다. 중성자 조사에 의하여 자기이력곡선은 변화가 없었으며, BNA, BNE 및 경도는 중성자 조사량에 따라 세 단계의 변화를 보였으며, 중성자 조사량이 10 n/㎠에서는 급격히 변하여 이들 사이의 상관관계가 있음을 알 수 있었다. 따라서 BNA와 BNE가 중성자 조사에 의한 재료의 미세 구조 결함을 조사하는데 비파괴적인 방법으로 가능성이 있음을 알 수 있었다. Hysteresis loop, Barkhausen noise(BN), and hardness were measured in the neutron irradiated RPV steel for various fluence, irradiated dose up to 10 n/㎠. The coercivity, remanence and maximum induction of neutron irradiated samples did not change significantly, but the BNA and BNE were decreased as the neutron irradiation increased. The changes of BNE and BNA were characterized by three stages with respect to neutron dose. The BNA and BNE were decreased with an increase of neutron dose to 10 n/㎠, and remained nearly constant up to 10 n/㎠, then were decreased rapidly with an increase of the neutron dose above 10 n/㎠. On the other hand, the hardness was observed revesely with the change of BNA and BNE.

과도한 운동으로 발생한 횡문근융해증에 의한 급성신부전증 1예

문철호,류보열,모성환,김태종,기장도,박용관,김용환,정종훈 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Rhabdomyolysis may be defined as a clinical and laboratory syndrome which releases muscle cell contents into the plasma, such as creatine phosphokinase, due to skeletal muscle injuries. It can be the result of many diverse causes including muscle disease, ischemia, genetic disorder, metabolic disorder, infectious disease, drugs, comatose state, trauma or vigorous exercise that can lead to acute renal failure as a complication. Since first reported in 1941, rhabdomyolysis-induced acute renal failure has been documented many times, and the major causes of this disease are carbon monoxide poisoning, snake bites, and etc in Korea Reports of acute renal failure after exercise-related rhabdomyolysis with myoglobinemia are rare. We report a case of acute renal failure caused by exercise-related rhabdomyolysis in a 20 year old man.

중성자에 조사된 원자로 압력용기 재료(SA508)의 Magneto-acoustic emission 효과

홍준화,박덕근,옥치일,김장환,이종규 韓國非破壞檢査學會 1999 한국비파괴검사학회지 Vol.19 No.6

원자로 압력용기 재료인 SA508 steel을 온도 70 ℃와 대기압하에서 최고 10 n/㎠까지 중성자를 조사시켜 조사량에 따른 미세경도 변화와 magneto-acoustic emission(MAE) 에너지를 측정하였다. 중성자 조사에 따른 경도의 변화는 조사량이 10 /㎠까지는 거의 일정하였으나, 조사량이 10 /㎠이상에서 급격히 증가하였다. MAE 에너지의 변화는 중성자 조사량에 따라 경도의 변화와 같은 형태로 변하였으나 그 변화량은 감소하여 그변화의 추이는 경도의 변화와는 역의 형태였고, 또한 MAE에너지의 상대적 변화와 경도 변화사이에는 아주 좋은 선형성을 보였다. 이러한 결과에서 SA508 강재는 10 /㎠이상의 중성자에 조사될 경우에 재료에 중성자 조사에 의한 미세 결함이 급격히 증가하여 전위(dislocation)이동에 대한 저항성을 나타내는 마찰경화의 증가가 경도의 증가를 유발하고, 또한 이러한 미세 결함은 자기장과의 반응에서는 90°자벽의 운동중에 자기탄성 변화를 유도하여 MAE 에너지의 감소를 유발함을 알 수 있었다. 그리고 경도의 변화량보다 MAE 에너지의 변화량이 더 크게 나타나, 중성자 조사에 의한 미세결함은 기계적 성질보다 자기적 성질에 더 민감하게 반응한다는 것을 알 수 있었다.따라서 MAE가 중성자 조사에 의한 재료의 미세 구조 결함을 비파괴적인 방법으로 평가하는 강력한 도구의 가능성이 있음을 알 수 있었다. Magneto-acoustic emission (MAE) energy and hardness were measured in the reactor pressure vessel steel (SA508 Steel) for the various neutron fluence, irradiated dose up to 10 n/㎠. The hardness was nearly a constant up to 10 n/㎠, but it was rapidly increased with an increase of the neutron irradiation above 10 n/㎠. It may be considered that the increase of hardness is due to the hindrance of dislocation motion induced defect clusters by irradiation. On the other hand, the MAE energy was slowly decreased as the neutron irradiation increased up to 10 n/㎠ and it was rapidly decreased with an increase of the neutron irradiation increased up to 10 n/㎠ and it was rapidly decreased with an increase of the neutron irradiation above 10 n/㎠. The decrease of the MAE energy may be considered as an increase of the defect clusters which is very sensitive to the 90°domain wall motion. Furthermore, the change of MAe energy and hardness had nearly a linear relationship, but the change of MAE energy was more significant than the change of the hardness. Therefore, MAe may be considered as a very useful technique for the nondestructive evaluation of irradiation damage.

Prognostic Implication of Anemia on Clinical Outcomes After Percutaneous Coronary Intervention with Drug-Eluting Stent

( Jong Seon Park ),( Sung Won Cho ),( Duk Woo Park ),( Hae Geun Song ),( Jung Min Ahn ),( Won Jang Kim ),( Jong Young Lee ),( Soo Jin Kang ),( Seung Whan Lee ),( Young Hak Kim ),( Cheol Whan Lee ),( S 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.-

Peformance Comparison : High Compression Image Coding Using Texture Segmentation

Jong Whan Jang,Jae G. Jeong,Yoo Suk Yang 한국통신학회 1993 Asia-Pacific Conference on Communications Vol.2 No.2

Prognostic Implication of Anemia on Clinical Outcomes After Percutaneous Coronary Intervention with Drug-Eluting Stent

( Jong Seon Park ),( Sung Won Cho ),( Duk Woo Park ),( Hae Geun Song ),( Jung Min Ahn ),( Won Jang Kim ),( Jong Young Lee ),( Soo Jin Kang ),( Seung Whan Lee ),( Young Hak Kim ),( Cheol Whan Lee ),( S 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1

Background: Anemia has been shown to be an independent predictor of long-term outcomes after percutaneous coronary intervention (PCI).The purpose of this study was to assess the impact of anemia on long-term clinical outcome of “real-world” patients reated by percutaneouscoronary intervention (PCI) using drug-eluting stents (DES). Methods: Clinical and outcome data on 2,849 patients who received DESimplantation were prospectively collected between March 2006 and December 2009. Patients were classified as anemic status using the World Health Organization definition (<12.0 g/dL in women and <13.0 g/dL in men). We compared clinical outcomes of patients with anemia (n=679) vs, without anemia (n=2170). Result: Median follow-up duration was 2.2 years. When compared with non-anemic patients, anemic patients hadhigher 2-year all-cause mortality (5.0% versus 1.8%; p<0.001) and combined major cardiovascular event (MACE; all-cause death, myocardialinfarction, stent thrombosis and cerebrovascular event; 6.5% versus 2.4%; p<0.001). After adjustment for baseline clinical and proceduralcharacteristics, anemia showed an independent association with higher incidence of 2-year MACE (adjusted hazard ratio (HR) 1.78, 95%confidence interval (CI) 1.14-2.78, p=0.012), and also higher trend of long-term mortality (adjusted HR 1.52, 95% CI 0.90-2.56, p=0.12).Conclusion: Status of preprocedural anemia was associated with increased mid-term MACE and mortality after PCI using DES in real-worldpatients. Key words: Anemia, Asian, Percutaneous coronary intervention, Drug-eluting stents.