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장석우(Suk Woo Jang), 최승국(Seung Kook Choi), 박수형(Suhyoung Park), 최학순(Hak Sun Choi), 양은영(Eung Young Yang), 이종남(Jong Nam Lee), 김대균(Dae Gyun Kim), 노재관(Jae Kwan Noh), 김은지(Eun Ji Kim), 정완규(Wan Gyu Jeong), 고순보(Sun Bo Ko) 한국육종학회 2018 한국육종학회지 Vol.50 No.3
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A new red butterhead lettuce (Lactuca sativa L.) with transverse broad elliptic, red leaves, ‘Sun Red Butter', with late bolting and high yield, was developed from a cross between ‘Jajusangchu' (red leaf color and half crisp) and ‘Dukseomjeokchukmyeon' (high yield). The crossing and selection for advanced lines was previously carried out using the pedigree method during the period 2001-2009. The advanced lines were evaluated for yield and adaptability at several locations in Korea (Gangwon-do, Gyeonggi-do, Chungcheongbuk-do, Jeollabuk-do, Gyeongsangnam-do, and Jeju-do) in 2011. The type of matured stage is early and medium butterhead lettuce. The shelf life of ‘Sun Red Butter' was four weeks longer than that of ‘Germania' at 4°C. The anthocyanin content of ‘Sun Red Butter' was lower than that of ‘Germania' at 11.2 mg/100 g. The BSL (latucin+8-deoxylactucin+lactucopicrin) content of ‘Sun Red Butter' was higher than that of ‘Germania' at 32.8 μg/g, DW. The marketable yield of ‘Sun Red Butter' was higher than that of ‘Germania' by 67% (at 621.4 g per plant), and ‘Sun Red Butter' showed a particularly improved yield under high-temperature cultivation in the field. Furthermore, ‘Sun Red Butter' had better taste characteristics and was crisper and sweeter than ‘Germania'. Therefore, we recommend that the new cultivar ‘Sun Red Butter' would be suitable for cultivation in spring and fall. Furthermore, this new cultivar could be harvested in a single harvest, as in a head lettuce, and could therefore be managed more efficiently and economically by farmers.
The physicochemical properties of sun-dried and cyclic freeze-thaw dried Alaska pollack were analyzed to compare the 2 drying processes. The moisture content and water activity of sun-dried Alaska pollack were higher than cyclic freeze-thaw dried and 1 year-aged cyclic freeze-thaw dried Alaska pollack (hwangtae). The relatively low temperatures used in cyclic freeze-thaw drying retards lipid oxidation compared to sun drying based on the acid and peroxide values, and the levels of thiobarbituric acid-reactive substances (TBARS) in the dried fish. The water holding capacity of cyclic freeze-thaw dried Alaska pollack aged for 1 year (hwangtae) under ambient conditions at the drying location was higher than that of sun-dried Alaska pollack. The swelling of myofibrilar filaments during cyclic freeze-thaw drying may be responsible for the softening of the dried muscle protein. Aging the cyclic freeze-thaw dried Alaska pollack for 1 year contributed to an increased yellowish color of the hwangtae.
Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.
Adjuvant therapy for completely resected esophageal squamous cell carcinoma is less commonly applied in clinical practice than neoadjuvant therapy, but it plays a substantial role in improving survival for esophageal cancer patients. This article presents a concise review of the evidence regarding adjuvant therapy for esophageal squamous cell carcinoma and future directions, particularly immunotherapy.
<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Rosacea is a common inflammatory skin disease, but it is hard to classify its subtype and grade severity. Due to these difficulties, topographic characteristics of rosacea lesions are not elucidated clearly. Objectives: To evaluate topographic differences according to subtype and severity Methods: 704 patients were analyzed and classified into 4 subtypes (erythematotelangiectatic(ETR), papulopustular (PPR), combined, phymatous(PHY)). Severity and clinical response were graded using 3-point numeric scale. Results: The most common subtype was ETR(55.7%), followed by combined type(22.6%). Cheek was the most commonly affected site(89.9%), followed by nose(56.5%), glabella(37.8%), nasolabial fold(17.2%) and periorbital area(9.8%). Glabella was significantly more frequently affected in combined type(69.2%) than in ETR(28.3%), regardless of severity. Same trend was seen with nasolabial involvement (39.0% in combined type vs 10.5% in ETR). Nose, glabella, nasolabial fold and periorbital area were more frequently invaded with higher severity (p=0.000). The complete response rate was significantly different between ETR and combined type (10.9% vs 26.0%). The co-occurrence of seborrheic dermatitis did not affect where lesions occur. Conclusion: As the severity of rosacea increases, glabella and nasolabial fold are invaded more frequently. The patients in combined type have higher glabella lesions. Glabellar involvement may serve as a prognostic indicator in rosacea.
BACKGROUND: Chemical fungicides not only may pollute the ecosystem but also can be environmentally hazardous, as the chemicals accumulate in soil. Biological control is a frequently-used environment-friendly alternative to chemical pesticides in phytopathogen management. However, the use of microbial products as fungicides has limitations. This study isolated and characterized a three-antifungal-enzyme (chitinase,cellulase,andβ-1,3-glucanase)-producing bacterium, and examined the conditions required to optimize the production of the antifungal enzymes. METHOD AND RESULTS: The antifungal enzymes chitinase, cellulase, and β-1,3-glucanase were produced by bacteria isolated from an sawmill in Korea. Based on the 16S ribosomal DNA sequence analysis, the bacterial strain AM50 was identical to Streptomyces sp. And their antifungal activity was optimized when Streptomyces sp. AM50 was grown aerobically in a medium composed of 0.4% chitin, 0.4% starch, 0.2% ammonium sulfate, 0.11% Na2HPO4, 0.07% KH2PO4, 0.0001% MgSO4, and 0.0001% MnSO4 at 30℃. A culture broth of Streptomyces sp. AM50 showed antifungal activity towards the hyphae of plant pathogenic fungi, including hyphae swelling and lysis in P. capsici, factors that may contribute to its suppression of plant pathogenic fungi. CONCLUSION(S): This study demonstrated the multi- antifungal enzyme production by Streptomyces sp. AM50 for the biological control of major plant pathogens. Further studies will investigate the synergistic effect, to the growth regulations by biogenic amines and antifungal enzyme gene promoter.
SJ compounds (SJ8002 and related compounds) are a group of novel anticancer agents (Cho, Chung, Lee, Kwon, Kang, Joo, and Oh. PCT/KR02/00392). To explore the anticancer mechanism of these compounds, we examined the effect of SJ8002 on microtubules of six human cell lines. At a high concentration (2 mg/mL), SJ8002 effectively disrupted microtubules of the six cell lines within 1 h. At lower concentrations (0.05~1.0 mg/mL), the antimicrotubule activity of SJ8002 varied defending on cell lines. The inhibition of in vitro polymerization of pure tubulin by SJ8002 suggested that SJ8002 acts on free tubulin, inhibits the polymerization of tubulin dimer into microtubules, and hence induces the depolymerization of microtubules.