만성주정중독자의 시각유발전위반응

설석구,김종길 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.4

Visual evoked potentials(VEP) were recorded on 24 male chronic alcoholics and 20 normal male controls. Alcoholic patients met the criteria of the DSM-Ⅲ-R for alcoholism, with a mean age 45 years and drinking history for an average of 21 years. Control-subjects were ate matched male volunteers tree of medical problems. The results were as follows : 1) Mean latency and mean amplitude of P100 were 98.35±3.33ms, 8.61±2.54μV in control group and 102±6.76ms, 5.22±2.28μV in alcohol group. The statistical analyses of above results using two-tailed t-test indicate that mean latency of P100(p<0.01)was significantly prolonged and mean amplitude of P100(p<0.01) was significantly decreased in alcoholic group compared to control group. 2) Of the 24 patients, 6(25%) had abnormal VEP. There were 5 patients with abnormally prolonged latency(above mean latency of control group+2.5SD) of P100 and 1 with abnormally prolonged interocular latency difference(above mean ILD of control group+2.5SD) only. Of the 5 patients with abnormally prolonged latency of P100, 3 had both of the abnormalities. These findings provide the possibility for pathological involvement of the visual pathway in chronic alcoholics. And so the authors suggest that VEP may be useful in detection of the early stage of alcohol induced brain damage.

무증상 당뇨병성 말초신경병증 환자의 H반사 검사

이종걸,이상수,이태연,박계연,이성현,한설희 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

抗精神病藥物이 血淸 Dopamine-β-Hydroxylase 活性度에 미치는 影響 : 慢性 精神分裂病患者를 中心으로

薛玹旭,禹鍾仁,李定均 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.2

To investigate the effect of antipsychotic drugs directly, the serum dopamine-beta-hydroxylase activty was measured before and after three weeks' washout period in chronic schizophrenics. Total number of subjects were eighty-two chronic schizophrenics, consisting of forty-eight male and thirty-four female patients. The diagnostic criteria was based on DSM-Ⅲ and duplicated assay was applied by modified Udenfriend method. The results were as follows; 1. After three weeks' washout period, the serum dopamine-beta-hydroxylase activity was 13.50±2.12 in male, 11.72±2.12 in total patients. Serum dopamine-beta-hydroxylase activity of female patients were significantly lower than in male patients.(p<0.001) 2. The range of serum dopamine-beta-hydroxylase in total patients was from 8.45 to 18.45㎛ol/min/1, which is relatively small compared with previous reports in the literature. 3. During the three weeks' washout period, the percent change was -8.81±17.35% in male (p<0.01), 1.94±20.92% in female(N.S), and -4.35±19.64%(p<0.05) in total patients compare to the serum dopamine-beta-hydroxylase activity of three weeks' washout period. The difference between male and female(p<0.02) is not clear. 4. During the three weeks' washout period, the absolute value of percent change was 16.48±10.36% in male, 17.71±13.93% in female, and 16.57±11.40% in total patients. (all, p<0.001) 5. The percent change of serum dopamine-beta-hydroxylase activity did not seem to be related to the type of drugs, dose of drugs, age, hospital duration, duration of illness, and the presence of active symptom. 6. In summary, the current findings suggest that the interpretation of data indicating low serum dopamine-beta-hydroxylase activity in medicated schizophrenics should be made with caution.

은행의 위험선호 변화가 은행성과에 미치는 영향

이종준,설병문 啓明專門大學 産業開發硏究所 2002 啓明硏究論叢 Vol.20 No.1

1990년대에는 금융시장의 환경변화로 인하여 대출금리가 예금금리보다 낮아지는 등 은행의 전통적인 이윤창출기능에 근본적인 변화가 발생하고 있다. 이러한 환경변화는 각 국의 감독기관이 제시한 은행의 건전성 기준과 국제결제은행의 위험가중자본비율기준의 영향과 관련이 있는 것으로 일시적인 현상으로 보기 어렵다. 금융시장의 발전으로 기업은 자금조달을 위하여 은행차입보다는 주식발행을 선호할 유인이 생겼으며, 가계부문 역시 제2금융권과의 거래가 활발해지고 있기 때문이다. 이러한 상황에서 은행 역시 자금운영을 대출위주에서 다양한 금융상품에 대한 투자로 확대하고 있다. 본 연구는 은행의 자산운영 변화로 인한 위험수준의 증감이 수익성에 미치는 영향을 실증적으로 분석하고 있다. 분석결과에 의하면 은행의 위험수준 변동과 수익성 변화는 무관하지 않은 것으로 보인다. The purpose of this study is to empirically examine bank behavior with respect to observed changes in risk-taking and performance. Under Basle Accord these variables are related to capital ratio and bank lending. Lending is influenced by any environment where changes in economic conditions cause changes in the probability of insolvency. If the probability of borrower default increases and hence the probability of bank failure increases, banks want to reduce their default risk and thus will reduce lending under the norm. The same with this case, If the cost of lending increases and hence the profit of bank reduces, banks will reduce lending under the norm. To complete the purpose of this study. the simultaneous equations model developed by Shrieves-Dahl(1992), and later modified by Aggarwal-Jacques(1998) to study the impact of risk-based capital, is used to examine how capital regulations simultaneously influenced bank risk-taking and performance. This study analyzes the annual data on domestic banks for the period from 1988 to 2000 and divided the period into two sub-periods, period I(1988-1992)·period II (1993-2000). Data were obtained from KIS-FAS database and Korea Bank annual reports. The main results of this study can be summarized as this. I find some evidence that supports significant relation between changes of ROA and risk-taking in period II. But I couldn't find any relationship in period I. The different result between periods maybe imply some effect of capital regulation.

國産 Praziquantel (Cestocide^(�)의 無鉤條蟲 및 廣節裂頭條蟲에 對한 治療效果

蔡鐘一,孫運睦,洪性琮,李純炯,徐丙卨 대한화학요법학회 1985 대한화학요법학회지 Vol.3 No.2

Praziquantel(Cestocide^ⓡ), Korean product, was tested for its efficacy in the treatment of Taenia saginata and Diphylobothrium latum infection during the period from May 1983 to October 1985, A total of 30 patients were treated with 10~30㎎/㎏ single dose of praziquantel and purged with 20~30g of magnesium sulfate to recover the worms. The results were as follows: 1. The patients were 26 cases of T. saginata and 4 cases of D. latum and after the treatment all of them discharged tapeworm segments with or without their scolices. The scolex recovery rate was 43.3%(from 11 and 2 cases of T. saginata and D. Iatum respectively). 2. The follow[up examination for eggs and/or proglottides performed 2~3 months later or 11 out of 17 scolex-unidentified cases gave all negative results. From the results it is concluded that praziquantel(Cestocide^ⓡ) in 10㎎/㎏ single dose is highly effective in treatment of these tapeworm infections.

加味鷄血藤湯이 Glutamate receptor와 Free radical 및 뇌손상 보호에 미치는 영향

안종석,김동희,김윤식,이용구,박종오,남궁욱,설인찬 대한동의병리학회 2003 동의생리병리학회지 Vol.17 No.3

This study was investigated to prove the effect of GMGHT on the gultamate receptor, free radical and brain damage in rats sujected to Brain Ischemia The results were as follows ; 1. GMGHT showed significant inhibitory effect of GMGHT on LDH release induced by NMDA, AMPA, and kinate. 2. GMGHT showed significant inhibitory effect of GMGHT on LDH release induced by BSO and Fe^2+. 3. GMGHT decreased coma duration time in a infatal dose of KCN and showed 30% of survival rate in a fatal dose. 4. GMGHT decreased ischemic area and edema incited by the MCA blood flow block. 5. GMGHT showed improvement of forelimb test after MCA occulusion in neurological exemination. 6. GMGHT showed no significant change after MCA occulusion in pathological observation as normal group. These results indicate that GMGHT can be used in the brain damage sujected to Brain Ischemia. Further study will be needed about the functional mechanism and etc.

腦卒中 食餌療法에 對한 文獻的 考察

安鍾石,薛仁燦 대전대학교 한의학연구소 2001 한의학연구소 논문집 Vol.10 No.1

In the literatual study on the diet treatment of JungPung(C.V.A) the results were as follows: 1.The principle of oriental medical dietary treatment is based on the YumYang Oh Haeng(陰陽五行) and QiMiLon(氣味論). 2.The principle of western medical dietary treatment attachs importance to the treatment of the total heat capacity control and balanced nutrition. 3.The western diet treatment of C.V.A was used to low salt diet, low fat diet and low calory diet, the oriental diet treatment was used to cereals and fruit composed of Qi() of HanYeulOnLang(漢熱溫冷) and Mi()of San Go Gam Sin Ham(酸苦甘辛箴). 4.In the analysis of oriental diet treatment of C.V.A used for cereals and fruits, the results were that Sung(性) is MiHan(微寒), Mi(味)is GamMiHan(甘微酸), Sung(性) is descending, Qi(氣) is YangJungJiYum(陽中之陰) and QiBak(氣薄), the effect is ChungYulYiSub(淸熱利水) GunBi(建脾) YikQi(益氣) etc.

Sn-xAg-0.5Cu 무연 솔더 볼의 파단특성 연구

정종설,이용성,신기훈,정성균,장동영 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

This paper presents a study on the failure characteristics of SnAgCu lead-free solder balls. To estimate the effect of Ag, three types of SnAgCu balls are first prepared by varying the weight percent of Ag (1.0, 3.0, 4.0 wt%) and then analyzed by reliability tests such as thermal shock, high speed ball shear, and drop tests. Thermal shock test reveals that the higher the weight percent of Ag is, the longer the fatigue life becomes. To the contrary, high speed ball-shear test and drop test show that the shear strength and the fracture toughness of solder balls are inversely proportional to the weight percent of Ag, respectively. Reasons for these observations will be further investigated in the future work.

推論과 證明指導에 관한 考察

김종구,임석훈,설영수 경북대학교 과학교육연구소 1997 科學敎育硏究誌 Vol.21 No.-

This study is to discuss the educational problem about whether an exact proof is useful in the secondary school mathematics education formally in the development of mathematical thought and whether we should teach students an exact proof up to an extent.

Adamkiewicz 동맥의 폐색에 의한 척수경색 1례

이광훈,이종걸,이태연,신동익,이성현,이상수,한설희,차상훈 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4