김정은 체제의 구축과 변화전망

박종문 ( Jong Moon Park ) 이실학회(구 한국경찰이론과실무학회) 2012 경찰연구논집 Vol.10 No.-

북한을 철권통치 했던 김정일이 사망하면서 아들인 김정은이 3대 권력을 세습하였다. 3년이라는 짧은 후계수업 기간과 권력기반마저 미약하여 많은 우려를 자아냈으나, 현재까지 별다른 어려움 없이 최고사령관과 당 제1비서, 당 중앙군사위원장, 국방위원회 제1위원장으로 추대되면서 북한의 최고 지도자가 되었다. 김정은은 아버지와 달리 TV생중계와 공개연설 그리고 스킨십 등으로 대중 친화적이고 새로운 정치스타일을 보이면서 긍정적인 북한의 변화를 예측하게 하는 한편 공개연설을 통해 김일성 주체사상과 김정일의 선군정치를 계승·발전시켜 군사강국·경제강국을 달성하겠다는 다짐과 장거리 미사일을 발사하고 핵개발을 포기하지 않을 것이라는 입장을 보이고 있다. 앞으로 김정은은 체제 안정을 위하여 대내적으로 군부세력을 관리하고 당의 권한을 강화시켜 지도력을 강화하고, 주민의 생활을 개선과 경제난국을 타개하기 위한 경제정책을 펼칠 것이다. 대외적으로는 국제적인 고립을 피하고 정권의 존속을 위하여 절대적인 후원국인 중국과 협조관계를 공고히 하고, 미국에 대해서는 한국을 배제한 채 강온정책으로 평화협정 채결과 경제지원을 받기 위해 노력할 것이다. 또 한국에 대해서는 이명박 정부의 ``원칙 있는 대북정책``에 극도로 반감을 표출하고 있어 현 정권에서는 대남강경정책을 펼치다가 차기 정부와는 새로운 돌파구를 찾을 것으로 보인다. 특히 2012년은 한국의 대통령 선거를 비롯한 한반도 주변 주요국들의 정권교체가 있는 해로서 김정은 체제의 안정성과 향후 대내외정책에 따라 동북아와 한반도의 평화에 절대적인 영향을 미칠 것이다. 따라서 북한의 대내외 정책 변화를 신속정확하게 파악하고 국제사회와 긴밀한 협력으로 김정은의 군사적 모험주의에 대비하고 북한의 경제 개선전략을 지원함으로써 갈등과 대립에서 협력과 공동번영의 한반도로 거듭나야 할 것이다. Immediately after his father Kim Jong-il`s death, the younger Kim Jong-un was hailed as “the great successor”. Even though some of experts expressed their concerns that Kim Jong-un took only 3-year-class to be a successor and his political background was not strong enough, without any difficulty, he has held the titles of the First Secretary of the Workers` Party of Korea, the Chairman of the Central Military Commission, First Chairman of the National Defence Commission of North Korea and the Supreme Commander of the Korean People`s Army. And also he was officially declared the supreme leader of North Korea. 57) Kim Jong-un shows that he has new and public-friendly style of leadership which is different from that of his father. This implicates that North Korea will change in a positive way. He made his first public speech as North Korea marked the 100th anniversary of the birthday of Kim Il-sung on 15 April, praising the “military first” doctrine and emphasizing the need of economic growth. A few months into his leadership, North Korea launched a long-range missile which it said would put a satellite into orbit. It shows that Kim Jong-un will not give up reinforcing North Korea`s nuclear capability. In the future, Kim Jong-un will control military authorities, strengthen his leadership and push ahead economic policy to overcome financial difficulties internally. Externally, he will cement friendly relations which have existed between North Korea and China to avoid international isolation and maintain his regime. In addition, he will try to conclude a peace treaty between North Korea and the United States and demand economic aid. Regarding South Korea, Kim Jong-un has antagonism toward policy of Lee Myung-bak administration on North Korea. Therefore he has taken his hard-lined offensive movements against South Korea and he may shift to more moderate policy toward South Korea in the next government. In particular, there will be some of important events this year, such as an upcoming presidential election in South Korea and change of government in other neighboring countries. The stability and internal/external policy of North Korea will have a strong influence on peace of Northeast Asia and Korean peninsular. In conclusion, South Korea should analyze the whole situation of North Korea promptly and accurately, cooperate with the U.S., China and the International Society, develop national security strategy against Kim Jong-un`s “military first” doctrine and support the economic development plan of North Korea. By doing so, the relationship between South Korea and North Korea will be improved for the better.

Correction: Bioinspired M-13 bacteriophage-based photonic nose for differential cell recognition

Moon, Jong-Sik,Kim, Won-Geun,Shin, Dong-Myeong,Lee, So-Young,Kim, Chuntae,Lee, Yujin,Han, Jiye,Kim, Kyujung,Yoo, So Young,Oh, Jin-Woo Royal Society of Chemistry 2017 Chemical Science Vol.8 No.2

<P>Correction for ‘Bioinspired M-13 bacteriophage-based photonic nose for differential cell recognition’ by Jong-Sik Moon <I>et al.</I>, <I>Chem. Sci.</I>, 2017, DOI: 10.1039/c6sc02021f.</P>

Nonextraction treatment of Class Ⅱ division 2 in an adult patient using microimplant anchorage (MIA)

Chae, Jong-Moon 대한치과교정학회 발행 2005 대한치과교정학회지 Vol.35 No.6

Maxillary anterior teeth were intruded and lingually root torqued with two maxillary anterior microimplants between the lateral incisors and canines. Overerupted maxillary canines were intruded with two other microimplants between the maxillary canines and first premolars. Maxillary posterior teeth and canines were distalized, then the maxillary incisors were retracted with two maxillary posterior microimplants between the first and second molars. The mandibular anterior teeth were intruded and the mandibular posterior teeth were extruded with conventional method such as anterior bite plane, intrustion arch and Class Ⅱ elastics. The mandible moved slightly forward after the correction of deep bite and retroclination of the upper incisors. Consequently, microimplant anchorage (MIA) provided absolute anchorage for simultaneous correction of Class Ⅱ canine and molar relationships and deep overbite. 상악 측절치와 견치의 치근 사이에 식립한 microimplant를 이용하여 상악 전치의 함입과 설측으로의 치근 이동을 얻을 수가 있었으며, 상악 견치와 제1소구치의 치근 사이에 식립한 microimplant를 이용하여 과맹출된 상악 견치를 함입시켰다. 또한 상악 제1,2대구치의 치근 사이에 식립한 microimplant를 이용하여 상악 견치 및 구치의 후방 이동 및 상악 전치의 후방 견인을 시행하였다. Anterior bite plane과 intrusion arch, 그리고 Ⅱ급 고무 등과 같은 전통적인 방법을 사용하여 하악 전치의 함입 및 구치부의 정출을 얻얼 수가 잇었으며, 과개 교합 및 상악 전치의 설측 경사가 해소 되면서 하악골이 전방으로 약간 이동하였다. 이와 같이 MIA는 Ⅱ급 2류 부정교합 환자에 있어서 Ⅱ급 견치 및 구치 관계 그리고 과개교합을 동시에 해소 하는데 절대적인 고정원을 제공하였다.

The Potential ‘O-GlcNAc-P’om’

Il Soo Moon(문일수),HyunSook Lee(이현숙),Hyung Jong Lee(이형종) 한국생명과학회 2013 생명과학회지 Vol.23 No.2

O-GlcNAc 화(O-GlcNAcylation)는 단백질의 serine이나 threonine에 N-acetylglucosamine (GlcNAc) 분자가 결합하는 것으로, 기존의 당단백질과 달리 세포질 및 핵단백질 모두에 일어난다. 또한 수정의 속도가 빠르고 가역적으로 일어남이 인산화 수식과 유사하다. 그러나 수많은 인산화효소와 탈인산화효소가 관여하는 것과 달리 O-GlcNAc 수식은 O-GlcNAc transferase (OGT)와 O-GlcNAcase (OGA) 단 두 개의 효소에 의하여 이루어진다. 이러한 단순한 조절기전은 세포가 내외환경에 즉시 적응할 수 있도록 진화한 것으로 해석된다. 즉, O-GlcNAc 수식은 특정한 단백질 하나 하나의 활성을 켜거나 끄는 것이 아니라, 세포의 신호전달과정의 효율을 전반적으로 조절하는 ‘가변저항기(rheostat)’ 역할을 한다. O-GlcNAc 수식은 흔히 같은 아미노산 혹은 그 주변의 아미노산이 인산화되는 것을 수반하는데, 이는 인산화와 함께 서로 조화를 이루어 세포활성을 조절하는 것으로 해석된다. 최근 O-GlcNAc이 더 나아가 O-GlcNAc-P로 인산화될 가능성이 제시되고 있는 바, 본 총설에서는 이의 가능성을 이론적으로 설명하고, 실제 실험결과를 소개한다. The addition and removal of N-acetylglucosamine (GlcNAc) molecules on serine or threonine residues of a protein is called O-GlcNAcylation. This post-translational modification occurs on both cytoplasmic and nuclear protein, and is fast and reversible as comparable to phosphorylation. In contrast to the phospho-signaling cycles, this emerging moon-lightening signaling is cycled by only two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). The simple machinery is a good evolutionary adaptation of a cell for quick accommodation to continuously fluctuating intra- and extracellular microenvironments. Rather than “switching” on or off a specific proteins ? this would be done by phosphorylation where numerous specific kinases and phosphatases are involved - O-GlcNAcylation would play a “rheostat” which would be much more delicately increase or decrease the efficacy of signal transductions in response to cellular nutrient and stress conditions. Interestingly, recent evidence indicates that O-GlcNAc is further modified by phosphorylation. The O-GlcNAc-P will upgrade the modulation efficiency of cellular processes to continuous ‘analogue’ level. So far, only one protein AP180 was reported to have O-GlcNAc-P on Thr310. But, proteomic data from our laboratory indicate that there are multiple O-GlcNAc-P proteins, constituting “O-GlcNAc-P’om”. This will focus on the possibility of existence of “O-GlcNAc-P’om”.

백화사설초 메탄올 추출물에 의한 HL-60 細胞 枯死過程에서의 cell cycle 關聯因子의 活性變化 硏究

한세희,이종범,문구,문석재,원진희,박래길,이종덕 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Objecives: Hedyotis diffusa is used to treat cancer in traditional Korea Medicine. So this study was carried out to examine the expression of cell cycle related genes in HL-60 cells undergoing apoptosis by the methanol extract of Hedyotis diffusa. Methods: 1. HL-60 cells were treated with various concentrations (from 200 to 50㎍/ml)of metnanol extract and H20 extract (200 ㎍/ml) of hedyotis diffusa. After 48 h later, the cells were tested for viability by MTT assay. 2. The HL-60 cells were treated with 200 ㎍/ml of methanol extract for the indicated periods. The whole cell lysates were prepared and analyzed by westem blotting using anti-p53 antibody. 3. The nuclear extract were prepared and analyed by western blotting using anti-p21 antibody, anti-p27 antibody, anti-cyclen A antibody, anti-cylin E antibody and anti-CDK2 antinbody. Results: 1. The methanol extract of Hedyotis diffusa induced the death of HL-60 cells in a dose dependent manner. 2. The methanol extract of Hedyotis diffusa makedly decreased the level of p21/Cipl and cyclin A in a time dependent manner. 3. The methanol extract of Hedyotis diffusa markedly increased tje ;eve; pf p27/Kip and cyclin E in a time dependent mammer. 4.The methanol extract of Hedyotis diffusa markedly did not affect the level of CDK2. Conclusions: These results provide evidence that expression of cell cycle related genes in HL-6- cells undergoing apoptosis by the methanol extract of Hedyotis diffusa mainly results from decreased level of p21/cipl and increased level of p27/Kipl of the cell cycle related genes.

老齡者의 建康을 위한 生活習慣 實態調査

申東敏,長鳳愚,李揆文,金賢俊,金昌範,崔宗洙,崔鍾晥,李鍾珏,金圭碩,趙庚旭,金鍾聲,朴鍾振 平生體育硏究所 論文集 1987 平生體育硏究所 論文集 Vol.2 No.-

With a view to examining the habit and method in which old people maintain and improve their health, we consulted 551 men and 444 women who were over 65 years old, and concluded as follows: 1. Habit of eating It's been revealed that most of the old people keep a regular eating hour, control the quantity of meal or eat a little food, and prefer vegetables to meat. 2. Mental health Old people feel the necessity for mental health and most of them (about 80%) keep good mental health without becoming pessimistic. Their chief concenrs have turned out to be about their sons and daughters and their own health and finance. 3. Managing Good Health It has been revelaed that old people do not possess any special kind of secret to keep good health but taking plenty of rest, regular meal, and proper exercise, and many of them (about 60%) have been shown to eat invigorant food that they can easily get around their living area. 4. Physical Functions It has been revealed that many old people are conscious of some symptoms about their parts of body and about to percent of them suffers from neuralgia. Some measures like medical aid especially for old people need to be taken as soon as possible. As we have found that the health-keeping method of old people consists plenty of rest, proper exercise, and appropriate nutrition, we can conclude that the recreatonal and culture facilities and programs for keeping old people in good health should be developed. It is also necessary to study food that contribute to their health and develop ways to get rid of the stresses to which they are exposed in their daily life. Presides, it is natural that government found an administrative department to deal with these matters effectively.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

웨이브렛 계수의 공간적 유사성을 이용한 비디오 영상 압축

문종현,방만원 木浦大學校 應用科學硏究院 2001 應用科學硏究誌 Vol.1 No.-

This paper presents a wavelet-based compression and decompression algorithm using spatial similarities of video sequences. The simulation results show that the proposed algorithm provides high compression ratio with proper image quality. It also outperforms the previous Hilton's algorithm in an image quality, compression ratio and running time, leading to compression ratio less than 0.2bpp, PSNR of 32 dB and running time of 10ms for a standard video image.

柴胡가 free radical에 의한 脂質過酸化物 生成에 미치는 效果

문진영,최미정,남경수,임종국 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

Antioxidant effects of aqueous Siho extract on lipid peroxidation were determined by TBA value and also by lipid peroxidation value during the autoxidation of Iinoleic acid. Siho extracts exhibited markedly antioxidant aCtivity, which inhibited 99% of linoleic acid peroxidation. And Siho extracts showed 42% scavenging effect on α,α-dlphenyl-β-pjcrylhydrazyl radical, also exhibited a 60-94% inhibitory effect on superoxide generation. Siho extracts dose-dependently protected the cell death induced by tert-butyl hydroperoxide (t-BHP) and significantly increased cell viability In the normal rat liver cell(Ac2F) . These results suggested that Siho might play a protective role in lipid peroxidation by free radicals. Key Words: lipid peroxidation ; Siho extracts; scavenging effect

親環境的 木構造의 類型開發에 關한 硏究

문정민,문종욱 진주여자전문대학 1999 論文集 Vol.22 No.-

An aim of architecture for environment intimacy is to save energy and resource and to protect environment. Our traditional houses structured with timbers of natural materials. The reason is because the timber structure is a suitable structure on the weather and natural features of our country. Wood h a s environmental intimacy in material production, no public nuisance of nature material manufacture, many directions of utilization, the other side has transformation, corrosion and fragility of fire. This study has a pivotal point that a style of the wooden structure is suitable on the actual condition in Korea and the future environment. Therefore, the purpose of this study is to suggest direction of wood frame at the houses with environmental intimacy. These results of this study will provide the methods for house design and composition plans of architectural structure, and application plans of environment or climate.