추이적 행렬을 이용한 패트리 넷의 교착 상태 확인 분석

이종봉,김병규,김종욱,이종근 國立 昌原大學校 產業技術硏究院 2004 産技硏論文集 Vol.18 No.-

본 연구에서는 패트리 넷에서의 교착 상태 확인을 추이적 행렬을 이용하여 분석하는 기법을 제안한다. 교착 상태란 패트리 넷에서 마킹이 더 이상 진행되지 못하고 서로 점화 가능 상태를 기다리는 상태로 자원 공유의 문제에서 많이 발생 가능하다. 따라서, 모든 플레이스와 트랜지션과의 관계를 나타내는 추이적 행렬을 이용하여 간단하게 확인분석이 용이한 기법을 제안한다.

카드뮴의 중추신경계 독성유발 기전

이종화,장봉기,박종안,박종영,김완종,우기민 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.3

Although numerous studies have shown that cadmium disturbs the normal biological processes in central nervous system the mechanism of toxicity is not well understood The present study has investigated the effect of cadmium on oxidative stress, Na+/K- ATPase activity and the aggregation of amyloid beta peptide(β-amylotd) in neuronal cell Ime, HT22 cell LC_(5) and LC_(50) of cadmium for HT22 cell resulted from MTT assay was 4 1 μM and 9 5 μM, respectively Cadmium(2 to 8 μM) dose-dependently increased the lipid peroxidation and decreased the content of glutathione Cadmium 4 μM showed a significant decrease in Na^(-)/K^(+) ATPase activity as compared with control group The aggregation of P-amyloid was accelerated in a dose-dependent manner by the treatment with 2 to 8 μM cadmium These results suggest that the neurotoxicity of cadmium can be mediated by the increase in oxidative stress and decrease in Na^(-)/K^(+) ATPase activity.

카드뮴이 마우스 뇌에서 아연의 항상성에 관여하는 유전자발현에 미치는 영향

박종안,여은영,남상훈,장봉기,이종화,김완종 한국환경독성학회 2004 환경독성보건학회지 Vol.19 No.4

Metallothionein (MT), a small protein molecule which can bind of release metal tons, is involved in the regulation of cellular metal homeostasis This study was investigated the accumulation of cadmium in blood, tissue (liver, kidney and brain), and the effect of cadmium on several key genes (MT-Ⅰ, MT-Ⅱ, ZnT-1) in zinc metabolism m the mouse Mouses weighing 20-25g were randomly assigned to control and cadmium treated group (Cd group) Cd group was intraperitoneally injected with cadmium 2, 4, 8 mg/kg and control group was administerd with saline Mouses of each group were sacrificed by decapitation 4 hours after the administration of cadmium Cadmium contents in blood, fiver, kidney and brain were increased by a dose-dependent manner Accumulation of cadmium was mainly occurred in liver and kidney Induction of MT-I and MT-11 protein was increased, but ZnT-1 expression was decreased to a dose-dependent manner by the treatment of 2~8mg/kg cadmium These results suggested that cadmium can be transported to brain and alter the expression of several key genes in zinc homeostasis.

아산시 호소들의 오염실태조사 및 그 대책

장봉기,이종화,박종범,민준호,박종안 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

The object of this study is to survey water quality of reservoirsin in Asan city. We also suggest some countmeasures for environmental preservation toward sustainable urban development of Asan city. We analyze water qualities (pH, DO, COD, SS, T-P, T-N and Chlorophyll-a) of reservoirs. The level of water quality of small reservoirs is in the range of level Ⅳ-Ⅴ higher than the level Ⅲ established by the Ministry of Environment. Especially, water quality of Sinchang, Youngin and Shinchung reservoirs is worser than that of other reservoirs. Water quality of Asan and Sapkyo lake is the range of level Ⅳ-Ⅴ. As the levels of T-P and T-N are level Ⅳ and level Ⅴ, respectively, eutrophication might be progressed. Reservoirs in Asan city were already serious polluted by inflow of wastewater from residents, animal husbandries and industries. Recently, Metropolitan Area Development Planning(MADP) for Asan bay-area was suggested by the Ministry of Construction. According to this plan, industrialization and urbanization of Asan area will rapidly progress. If sewage and wastewater treatment facilitiesare not provided, water quality of reservoirs in Asan city will be worse. In order to prevent of environment pollution, first, the impact of industrialization and urbanization of Asan area on the environment should be considered at the beginning of MADP. Second, total effluent regulation of water pollution, air pollution and soil wastes, based on the self-purification of the Asan city environment, should be enforced.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

老齡者의 建康을 위한 生活習慣 實態調査

申東敏,長鳳愚,李揆文,金賢俊,金昌範,崔宗洙,崔鍾晥,李鍾珏,金圭碩,趙庚旭,金鍾聲,朴鍾振 平生體育硏究所 論文集 1987 平生體育硏究所 論文集 Vol.2 No.-

With a view to examining the habit and method in which old people maintain and improve their health, we consulted 551 men and 444 women who were over 65 years old, and concluded as follows: 1. Habit of eating It's been revealed that most of the old people keep a regular eating hour, control the quantity of meal or eat a little food, and prefer vegetables to meat. 2. Mental health Old people feel the necessity for mental health and most of them (about 80%) keep good mental health without becoming pessimistic. Their chief concenrs have turned out to be about their sons and daughters and their own health and finance. 3. Managing Good Health It has been revelaed that old people do not possess any special kind of secret to keep good health but taking plenty of rest, regular meal, and proper exercise, and many of them (about 60%) have been shown to eat invigorant food that they can easily get around their living area. 4. Physical Functions It has been revealed that many old people are conscious of some symptoms about their parts of body and about to percent of them suffers from neuralgia. Some measures like medical aid especially for old people need to be taken as soon as possible. As we have found that the health-keeping method of old people consists plenty of rest, proper exercise, and appropriate nutrition, we can conclude that the recreatonal and culture facilities and programs for keeping old people in good health should be developed. It is also necessary to study food that contribute to their health and develop ways to get rid of the stresses to which they are exposed in their daily life. Presides, it is natural that government found an administrative department to deal with these matters effectively.

허혈성 심질환에 있어서 아데노신 급속 정맥투여후 관동맥압의 변화에 관한 연구

봉종대,오종용,배성한,신원용,김철현,이광희,최태명,현민수,김성구,권영주 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Background: Adenosine interacts with A1 receptors present on the extracellular surface of cardiac cells, activating K+channels in a fashion. It produces coronary vasodilatation and AV nodal block. The half-time is one to six second and has ultra-short action. In ischemic heart disease, fractional flow reserve(FFR) can be achieved safely with intravenous adenosine infusions at a rate of 150㎍/kg/min which cause maximal coronary hyperemia. Purpose: We investigated the patients who have had ischemic heart disease(n=8). After adenosine intravenous administration(150㎍/kg/min), the effect cause maximal hyperemia of coronary artery. During peak maximal hyperemia, we reported clinical findings, coronary hemodynamics and electrocardiogram findings. Methods: After diagnostic coronary angiography and left ventriculography, catheter was advanced into the ostium of coronary artery. We investigated coronary hemodynamics such as systolic coronary artery pressure, diastolic coronary artery pressure, mean coronary artery pressure and heart rate. To assess the use of adenosine for determination of fractional flow reserve, hemodynamics and electrocardiogram were measured at basal state and during peak maximal hyperemia. Results: Symptoms developed 1.5-2 minute after adenosine intravenous administration and each symptom disappeared 2-2.5 minute after adenosine administration. Two patients represented asymptomatic appearance and six patients complained of flushing, chest pain, palpitation and headache. In eight patients with ischemic heart disease, 1.5 minute after venous administration of 150㎍/kg/min of adenosine, coronary artery pressure decreased and heart rate increased significantly. Conduction abnormalities after administration of 150㎍/kg/min of adenosine were transient 2nd degree AV block 2 cases(25%). Conclusions: Adenosine is a potent ultra short-acting vasodilator. Although coronary artery pressure decreased and heart rate increased and mild cardiovascular symptoms occurred after continuous infusion of 150㎍/kg/min of adenosine, it is useful as an agent for determination of fractional flow reserve.

Capsaicin이 동통억제효과를 나타내는 기전에 관한 연구

이종은,김봉옥,이원택,윤호,박경아 대한해부학회 1995 Anatomy & Cell Biology Vol.28 No.5

직접 황 회수공정에서 Ce_(1-x)Zr_(x)O₂촉매를 이용한 반응특성 연구 : H₂O 와 석탄가스의 영향 Effect of H₂O and Coal Gas

김봉석,이종대,전진혁,박노국,류시옥,이태진,김재창 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.2

본 연구는 직접 황 회수공정에서 H_(2)O와 석탄가스의 영향에 대해서 조사하였다. Ce_(0.8)Zr_(0.2)O_(2)촉매를 이용하여 H_(2)O가 반응에 미치는 영향을 조사한 결과, 산화제인 H_(2)O의 첨가에 의해 반응가스의 환원력이 저하됨을 알 수 있었다. CO/H_(2)O-TRP 실험을 통해서는 반응온도 영역에서 water gas shift 반응이 일어나는 것을 확인 할 수 있었고, H_(2)O의 재산화 실험으로부터 환원된 촉매가 H_(2)O에 의해 재산화 됨을 알 수 있었다. Ce_(0.8)Zr_(0.2)O_(2) 촉매하에서 석탄가스를 환원제로 사용하여 반응온도 (500℃), 공간속도(30,000 ㎖/g-catㆍh), [CO+H_(2)]/[SO_(2)] 몰비(2.5)의 반응조건에서 실험한 결과 최대 75.8%의 원소 황 수율을 얻을 수 있었다. 이는 환원제로 석탄가스를 이용함으로써 H_(2)O에 의한 부반응을 억제할 수 있었으며 경제적인 측면에서 유리하므로 공정기술의 실증화 가능성을 향상시킬 수 있음을 확인할 수 있었다. The effect of H₂O and coal gas on a direct sulfur recovery process using Ce_(1-x)Zr_(x)O₂ catalysts was investigated in this study. As the reducing power of reactants was lowered in the present of H₂O, the activity of catalysts decreased. Temperature programmed reduction experiments showed that a water gas shift reaction took place in the temperature range of this study and that the reduced catalyst was re-oxidized by H₂O. DSRP was carried out on Ce_(1-x)Zr_(x)O₂ catalysts using a coal gas as a reductant. Maximum 76.8% yield of elemental sulfur was obtained at 500℃ with a space velocity of 30,000㎖/g-cat·h and [CO+H₂]/[SO₂] ratio of 2.5. The side reaction by H₂O could be inhibited using a coal gas.

강섬유로 보강한 재생골재 콘코리트의 강도특성

구봉근,김창운,류택은,이재범,류연종,이현석 충북대학교 산업과학기술연구소 2002 산업과학기술연구 논문집 Vol.16 No.1

This study was performed to investigate the strength characterstics of steel fiber reinforced recycled aggregate concrete. Test specimens were prepared with compressive, split tensile, flexural specimens and tested by ultimate strength. A superplasticizer and fly-ash were added to the mix to improve performance of recycled concrete. Test-variables are substitution of recycled aggregate(0, 30, 50%), steel fiber length(0, 30, 50, 60mm), steel fiber content(0, 0.5, 1.0, 1.5%). Test-specimen were classified by test-variables. The experimental results on the various engineering properties of steel fiber reinforced recycled aggregate concrete using waste concrete are summarized as follows. It was found that the compressive and split tensile strength were proportionally affected by quantities of recycled aggregate substitutions, but flexural strength wasn't. The maximum compressive strength was 392 kgf/㎠( series 4 : R30 L30 V1.0 A20 ), the maximun split tensile strength was 40 kgf/㎠( series 7 : R30 L30 V1.5 A20) and the maximum flexural strength was 62 kgf/㎠( series 7 : R30 L30 V1.5 A20 ).