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Syntactic Differences of Plurality Markers
Joh,Yoon-kyoung 한국영미어문학회 2011 영미어문학 Vol.- No.98
There are two crucial syntactic differences found among plurality markers. Dependent plurals and anti-quantifiers work at the phrasal level as opposed to ordinary plurals that apply to the lexical level. More specifically, ordinary plurals are adjoined to the X level while anti-quantifiers attach to the full-fledged XP level. Dependent plurals, however, have the in-between status syntactically and combine with the X'-structure. Another difference is found between ordinary plurals and dependent plurals, on the one hand, and anti-quantifiers, on the other, in the respect that the former is a morpheme while the latter is a phrase that can take its own complement. These different statuses seem to account for why plural forms are intrinsically ambiguous whereas anti-quantifiers are unambiguously more expressive in their semantics as well as in their syntax than ordinary plurals and dependent plurals.
Yoon-kyoung Joh 서울대학교 언어교육원 2020 語學硏究 Vol.56 No.1
This paper claims that adorning materials in middles can commonly be translated into adverbials since modality, negation, and focus can all be expressed using various types of adverbials. Through the analytical lens that views middle constructions as distributivity constructions that are essentially reduced to plurality, this common property among adorning materials in middles is highly interesting. Thus, this paper accounts for the adorning materials in middles in Joh’s (2016) analysis, which treats adverbials in middles as one of distributivity’s core arguments. This paper also discusses how adverbials that are implicitly inserted in middle sentences can be conditioned. To answer this question, this paper relies on the differentiating effect that Sohn (2003) examined, extending the previously proposed unexpectedness condition.
Jo, H.,Hwang, D.,Kim, J.K.,Lim, Y.H. Pergamon ; Elsevier Science Ltd 2017 Food and chemical toxicology Vol.108 No.1
Strengthening intestinal tight junctions (TJ) provides an effective barrier from the external environment and is important for recovery from inflammatory bowel disease. Oxyresveratrol (OXY), an isomer of hydroxylated resveratrol, is isolated from many plants. The aim of this study was to investigate the effect of OXY on intestinal TJ and to elucidate the mechanism underlying the OXY-mediated increase in TJ integrity in human intestinal Caco-2 cells. OXY-treated Caco-2 cell monolayers showed decreased monolayer permeability as evaluated by paracellular transport assay. The results showed that OXY significantly increased the levels of TJ-related genes and proteins (Claudin-1, Occludin and ZO-1) compared with those of the negative control. OXY activated protein kinase C (PKC) and increased expression levels of mitogen-activated protein kinase (MAPK) genes. OXY also increased gene and protein levels of the transcription factor Cdx-2. Expression levels of TJ, PKC and Cdx-2 proteins and transepithelial electrical resistance (TEER) value decreased in OXY-treated Caco-2 cells following treatment with a pan-PKC inhibitor compared with those of the untreated control. In conclusion, OXY strengthens the integrity of the intestinal TJ barrier via activation of the PKC and MAPK pathways.
A highly sensitive and selective impedimetric aptasensor for interleukin-17 receptor A
Jo, H.,Kim, S.K.,Youn, H.,Lee, H.,Lee, K.,Jeong, J.,Mok, J.,Kim, S.H.,Park, H.S.,Ban, C. Elsevier Applied Science 2016 Biosensors & bioelectronics Vol.81 No.-
Interleukin-17 receptor A (IL-17RA) has been recognized as a valuable biomarker for diverse diseases, including autoimmune diseases. In this work, an electrochemical biosensor with great sensitivity and selectivity toward IL-17RA was fabricated using an IL-17RA aptamer (K<SUB>d</SUB>=14.00nM) for the first time. The aptasensor was manufactured using electrodeposition of gold nanoparticles, and then quantitative detection of IL-17RA was performed based on impedimetry. The developed sensor exhibited a superior analytical performance for IL-17RA with a wide dynamic range of 10-10,000pg/mL in buffer and a detection limit of 2.13pg/mL, which is lower than that of commercially available ELISA kits. In addition, we validated the high specificity of the designed aptasensor to only IL-17RA, which showed good sensitivity even in human serum solution. Furthermore, the detection of the differentiated HL-60 cells expressing IL-17RA was successfully performed. Clinical applicability of the sensor was also demonstrated utilizing neutrophils separated from asthma patients. It is expected that the fabricated aptasensor will become an excellent diagnostic platform for IL-17RA-mediated diseases.
Jo, H.,Choi, H.,Choi, M.K.,Song, N.,Kim, J.H.,Oh, J.W.,Seo, K.,Seo, H.G.,Chun, T.,Kim, T.H.,Park, C. Academic Press 2012 Virology Vol.422 No.2
Pooled genomic DNA from 10 dogs was subjected to polymerase chain reaction with primers targeting the retroviral pro/pol region. Sequence analysis of 120 clones obtained by PCR revealed 81 of retroviral origin. Subsequent analysis of the dog genome (CanFam 2.0) by BLAST investigation using degenerate PCR products and previously identified retroviral sequences permitted the identification of additional retroviral γ and β sequences. A phylogenetic analysis using the retroviral protease (PR) and reverse transcriptase (RT) sequences in the dog genome resulted in identification of 17 γ and 7 β families. In addition, we also identified 167 spuma-like ERV elements from CanFam 2.0 based on sequence homology to murine (Mu)ERV-L and human (H)ERV-L. Our results could contribute to the understanding of the influence of retroviruses in shaping the genome structure and altering gene expression by providing quantitative and locational information of ERV loci and their diversity in the dog genome.
Jo, H.,Yoo, J.S.,Ok, K.M. Elsevier Sequoia 2016 JOURNAL OF ALLOYS AND COMPOUNDS Vol.672 No.-
Activator-doped noncentrosymmetric (NCS) bismuth tellurite solid solutions, Bi<SUB>2-x</SUB>Ln<SUB>x</SUB>TeO<SUB>5</SUB> (Ln = Ce and Eu), have been successfully synthesized by solid state reactions. Crystal structure determination by powder X-ray diffraction using Rietveld method suggests that the solid solutions crystallize in the polar space group, Abm2 with pseudo-three-dimensional frameworks consisting of asymmetric polyhedra. Powder nonlinear optical (NLO) measurements, using 1064 nm radiation, reveal that the origin of large second-harmonic generation (SHG) efficiency of Bi<SUB>2-x</SUB>Ln<SUB>x</SUB>TeO<SUB>5</SUB> is the polarization arising from the alignment of lone pair cation, Bi<SUP>3+</SUP>. Photoluminescence (PL) intensity of Bi<SUB>1.9</SUB>Ce<SUB>0.1</SUB>TeO<SUB>5</SUB> increases as temperature increases attributed to the greater occupation of the higher excited state. PL intensity of Bi<SUB>1.9</SUB>Eu<SUB>0.1</SUB>TeO<SUB>5</SUB>, however, increases as temperature decreases attributable to the distinct emission mechanisms at different temperatures. PL measurements also strongly suggest that the Bi<SUP>3+</SUP> sites are in unsymmetrical coordination moieties within the framework.
Jo, H.,Han, S.,Park, J.,Choi, M.,Han, S.H.,Jeong, T.,Lee, S.Y.,Kwak, J.H.,Jung, Y.H.,Kim, I.S. Pergamon Press 2016 Tetrahedron Vol.72 No.4
<P>The rhodium(III)-catalyzed mild and site-selective C-H allylation of 2-arylbenzo[d]thiazoles and 2-arylbenzo[d]oxazoles with allylic phosphonates and allylic carbonates is described. This transformation provides an efficient construction of C2-allylated, crotylated and prenylated 2-arylbenzo[d] thiazoles and 2-arylbenzo[d]oxazoles. In addition, this protocol can be applied to the formation of 2-arylbenzo[d]thiazole scaffolds containing an allylic alcohol group by using of 4-vinyl-1,3-dioxolan-2-one and vinyl oxirane as coupling partners. (C) 2015 Elsevier Ltd. All rights reserved.</P>