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좌골신경 손상 후 스트렙토조토신 유도성 당뇨병에 의한 축사재생의 지연 효과
황진연 ( Jinyeon Hwang ),김기중 ( Ki-joong Kim ),남궁욱 ( Uk Namgung ) 대전대학교 한의학연구소 2020 혜화의학회지 Vol.29 No.1
Objective: The goal of this study is to investigate whether peripheral axonal regeneration is affected by diabetes in experimental animals. Method: Sprague Dawely rat was injected with 45~50 mg/kg of streptozotocin (STZ) to generate an animal model of diabetes. Three months after STZ injection, sciatic nerve (2 cm length) was removed and the same length of nerve segments from STZ-injected animal or from control animal (CTL) was transplanted into STZ - injected animals (STZ - STZ and STZ - CTL respectively). Similarly, sciatic nerve segments from STZ - injected animal or from control animal were grafted into the control animals (CTL - STZ and CTL - CTL respectively). All animals were sacrificed 2 weeks after transplantation. Sciatic nerve sections were prepared and subjected to immunofluorescence staining analysis. Results: Immunofluorescence staining for NF - 200 showed that distal elongation of regenerating axons reached 40~80% of proximal neve in both CTL - STZ and CTL - CTL groups. However, distal elongation in both STZ - STZ and STZ - CTL groups were 20~60% of proximal nerve. Furthermore, measurement of axonal regeneration after immuno - staining with SCG10 showed that the scores of distal elongation relative to proximal nerve were 50~90% in CTL - CTL and CTL - STZ groups and 10 - 60% in STZ - CTL and STZ - STZ. Conclusions: Our data showed that the levels of axonal regeneration were not affected irrespective of whether they were from STZ- or CTL graft, but were greatly reduced when the nerves were transplanted into the STZ host.
2차원 회전형 Bounding Box 기반 객체 검출 네트워크
김진연(Jinyeon Kim),박종희(Jonghee Park),장성준(Sung-Joon Jang) 대한전자공학회 2021 대한전자공학회 학술대회 Vol.2021 No.6
In this paper, we propose a object detection network based 2D rotated bounding box for arbitrary-oriented object detection. To reduce computational burden, we use a backbone network as a one stage network and add angle detection parameters in a layer without network changes. In addition, we propose decision rules of rotated bounding box, leading to precise feature extraction.
국내 공기 중 섬유상 물질의 존재실태와 석면의 분석방법에 대한 고찰
황진연 ( Jinyeon Hwang ),오지호 ( Jiho Oh ),이효민 ( Hyomin Lee ),이진현 ( Jinhyun Lee ),손병서 ( Byeongseo Son ) 한국광물학회 2015 광물과 암석 (J.Miner.Soc.Korea) Vol.28 No.2
부산과 울산의 중심지역에 대해 공기 중의 분진시료를 채취하여, 위상차현미경, 위상차분산현미경, 주사전자현미경 등으로 석면을 분석한 결과, 석면은 검출한계 이하로서 확인되지 않았다. 공기중의 분진시료에는 섬유상물질이 다수 포함되었으나, 이들은 대부분 유기질 섬유인 것으로 나타났다. 무기질 섬유물질로는 암면, 세라믹섬유, 석고 등이 소량 포함되었으며, 비섬유상인 석영, 방해석, 장석등의 광물도 가끔 관찰되었다. 국내의 공기 중 분진의 석면분석은 주로 위상차현미경으로 관찰하는 것으로 규정되어 있으나, 이것만으로는 석면의 식별이 불가능한 것으로 나타났다. 따라서 일본 JIS법과 같이 저온회화 처리 장치에 의한 유기물질 제거 후에 분산염색법으로 석면을 식별하고 계수하는것이 효율적인 것으로 사료된다. Dust samples collected from air in metropolitan areas of Busan and Ulsan were analyzed by phase contrast microscopy, phase contrast dispersion microscopy and SEM. Asbestos concentration in dust samples was lower than detection limit. Many fibrous materials were observed in dust samples, but most of them were organic fibers. Inorganic fibers such as rock fiber, ceramic fiber and gypsum were contained in the samples and non-fibrous minerals such as quartz, calcite and feldspar were also occasionally observed. Domestic law requires that asbestos in air dust is mainly analyzed by phase contrast microscopy. From this study, however, precise analysis of asbestos was almost impossible by this method only. As indicated in JIS method of Japan, therefore, count and identification of asbestos were more efficient by dispersion staining method after removing organic materials in samples by low temperature incinerator.