Both endurance- and resistance-type exercise prevents neurodegeneration and cognitive decline in mice with impaired glucose tolerance

Jinhee,Woo,Ki-Ok,Shin,Chan-Ho,Park,Byung-Kon,Yoon,Do-Yeon,Kim,Ju-Yong,Bae,Yul-Hyo,Lee,Kangeun,Ko,Hee-Tae,Roh 한국응용과학기술학회 (구.한국유화학회) 2019 한국응용과학기술학회지 Vol.36 No.3

The purpose of this study was to investigate the effects of different types of exercise training on neurodegeneration and cognitive function in mice with impaired glucose tolerance (IGT). Thirty-six male C57BL/6 mice were randomly assigned to the control (CO, n = 9) and impaired glucose tolerance (IGT, n = 27) groups. The IGT group consumed 45% high fat diet for 4 weeks and received 40 mg/kg of streptozotocin twice in the lower abdomen to induce IGT. After the IGT induction period, the IGT group was subdivided into IGT + sedentary (IGT, n = 9), IGT + endurance exercise (IGTE, n = 9), and IGT + resistance exercise (IGTR, n = 9). The IGTE and IGTR groups performed treadmill and ladder climbing exercises 5 times per week for 8 weeks, respectively. Fasting glucose and glycated hemoglobin (HbA1c) levels were significantly higher in IGT group than in CO, IGTE, and IGTR groups ( p < 0.05). HOMA-IR was significantly higher in IGT group than CO group ( p < 0.05). Hippocampal catalase (CAT) was significantly lower in IGT group than in CO group ( p < 0.05), while beta-amyloid (Aβ) was significantly higher in IGT group than in CO group ( p < 0.05). Hippocampal tau was significantly higher in IGT group than in CO, IGTE, and IGTR groups ( p < 0.05). The Y-maze test performance for cognitive function was significantly lower in IGT group than in CO, IGTE, and IGTR groups ( p <0.05). These results suggest that IGT induces neurodegeneration and negatively affects cognitive function, while regular exercise may be effective in alleviating neurodegeneration and cognitive decline regardless of exercise type.

Effect of resistance training at different intensities on hippocampal neurotrophic factors and peripheral CCL11 levels in obese mice

Jinhee,Woo,Hee-Tae,Roh,Chan-Ho,Park,Byung-Kon,Yoon,Do-Yeon,Kim,Ki-Ok,Shin 한국응용과학기술학회 (구.한국유화학회) 2019 한국응용과학기술학회지 Vol.36 No.3

We investigated the effect of moderate- and high-intensity resistance training on hippocampal neurotrophic factors and peripheral CCL11 levels in high-fat diet (HFD)-induced obese mice. C57/black male mice received a 4 weeks diet of normal (control, CON; n = 9) or a high-fat diet (HF; n = 27) to induce obesity. Thereafter, the HF group was subdivided equally into the HF, HF + moderate-intensity exercise (HFME), and HF + high-intensity exercise (HFHE) groups ( n = 9, respectively), and mice were subjected to ladder-climbing exercise for 8 weeks. The hippocampal brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) levels were significantly lower in the HF group than in the CON group ( p < 0.05). In addition, in the HFME and HFHE groups were significantly higher than in the HF group ( p < 0.05). The peripheral CCL11 levels were significantly higher in the HF group than in the CON group ( p < 0.05). In addition, in the HFME and HFHE groups were significantly lower than in the HF group ( p < 0.05). However, there was no significant difference according to the exercise intensity among the groups. Collectively, these results suggest that obesity can induce down-regulation of neurotrophic factors and inhibition of neurogenesis. In contrast, regardless of exercise intensity, resistance training may have a positive effect on improving brain function by inducing increased expression of neurotrophic factors.

바이든 시기 미중관계 변화 가능성: 기후변화 이슈를 중심으로

林秦喜 ( Lim¸ Jinhee ) 현대중국학회 2021 現代中國硏究 Vol.23 No.3

2021년 1월, 미국 바이든 정부가 새로 취임한 이후 미국의 향후 대내외 정책에 관한 의견과 전망이 분분하다. 특히 2017년 트럼프 행정부 취임, 이어진 2018년 무역 갈등 이후 악화 일로를 걸으며 ‘탈냉전 이후 최악’이라 평가를 받았던 미중관계에 대한 관심이 높다. 미중관계가 뜨겁던 과거로 돌아갈 것이라는 장밋빛 전망은 드물지만, 동시에 바이든 정부 인사의 발언과 기고를 보면 ‘경쟁과 공존’이라는 트럼프 정부와 대별되는 바이든 정부의 접근방식도 분명해 보인다. 그리고 그 공존의 시작과 계기로 흔히 언급되는 것이 글로벌 기후변화 이슈이다. 그런데 실제로 바이든 시기에 기후변화 이슈와 관련하여 중국과 협력하는 상황이 재현될까? 그리고 이로써 긴장 국면 일로였던 미중관계 역시협력 모멘텀을 되살리며 새로운 국면을 맞이할까? 본 논문은 이러한 질문에서 시작한다. 그에 대한 답을 얻는 과정으로 첫 번째 장에서 관련 배경과 문제 제기를, 두 번째 장에는 기후변화 이슈와 미중협력 필요를 고찰한다. 세 번째 장에서 바이든 시기까지 간단한 미중관계 흐름과 기후변화 정책을, 네 번째 장에서 실제로 기후변화 이슈가 돌파구가 될 것인지, 마지막 장에는 분석 정리와 시사점을 제시하려 한다. Since the inauguration of the Joe Biden administration in January 2021, opinions and prospects have been divided on future of the U.S. domestic and foreign policies. In particular, interest is high in the U.S.-China relationship, which has been evaluated as the worst since the post-Cold War, as it has deteriorated since the inauguration of Trump administration in 2017 and the U.S.-China trade conflict in 2018. It is rare to see rosy prospects that U.S.-China relations will return to the old good days, but at the same time, the Biden administration’s approach, distinct from the Trump administration, of ‘competition and coexistence’, is also evident from the comments and contributions of Biden administration officials. But will there actually be a recurrence of the cooperation with China on climate change issues during the Biden period? And will the U.S.-China relations, which had been a tense situation, also come to a new phase by reviving the momentum for cooperation? This paper begins with these questions. In the process of obtaining answers, the first chapter explains the background and research questions, and the second chapter considers climate change issues and the necessity of U.S.-China cooperation. The third chapter presents U.S.-China relations and climate policies to the new era of Biden, and the fourth chapter analyzes whether climate change issues will actually be a breakthrough in the U.S.-China relations. In the conclusion, the fifth chapter presents analysis result and implications.

텍스트 마이닝을 활용한 코로나19 이후 온라인수업 관련 연구 동향 분석

한진희 ( Han¸ Jinhee ),한가영 ( Han¸ Gayoung. ) 대한영어영문학회 2021 영어영문학연구 Vol.47 No.3

This study aimed to analyze the trends of research in online education after COVID-19 using text mining techniques. The research subjects were the 212 Korean abstracts related to online education from 2020 to April, 2021 in Korea. The analysis of text mining and topic modeling were conducted through Textom 5.0 and UCINET 7.724. Findings revealed that keywords such as ‘class’, ‘learners’, ‘education’, ‘learning’, ‘instructors’, ‘online’, and ‘university’ were the main ones, and keywords with high centrality were ‘online education’, ‘class’, ‘learners’, ‘education’, and ‘research’. Additionally, the topics of about 35.6% of the total papers were related to the keywords like ‘class’, ‘online education’, and ‘learners’. This study is meaningful in that it identified the achievements of the research about online education conducted after COVID-19, and gave implications for future research. (Changshin University)

Eigenvalue Analysis of Overhang Structures by Pseudospectral Method

Lee, Jinhee Research Institute of Science and Technology HONGI 2005 Hongik Journal of Science and Technology Vol.9 No.-

The pseudospectral method is applied to the free vibration analysis of overhang structures which consist of Timoshenko beams. The analysis is based on the Chebyshev polynomials. Each section of the overhang structure has its own basis functions, and the continuity conditions at the intermediate support as well as the boundary conditions are treated separately as the constraints of the basis functions. Natural frequencies of overhang structures with pinned-pinned-free support conditions are provided for different thickness-to-length ratios and for different span ratios. The computed natural frequencies agree with those of Euler-Bernoulli beams when the thickness-to-length ratio is small but deviate considerably as the thickness-to-length ratio grows larger.

아동친화도시 실현을 위한 공공시설 조성 경향 연구

박진희 ( Park¸ Jinhee ) 한국공간디자인학회 2021 한국공간디자인학회논문집 Vol.16 No.7

(연구배경 및 목적) 아동의 권리를 보장하고 삶의 질을 높여서 아동이 살기 좋은 도시를 실현해야 한다는 당위성은 전 세계적으로 공감대를 형성하고 있으며 각국의 도시가 이를 실현하기 위해 노력하고 있다. 우리나라의 지자체도 아동친화도시의 조성을 선포하며 실천하고 있으며 2013년을 시작으로 아동친화도시 인증을 받거나 이를 추진 중인 지자체는 지속적으로 증가하고 있다. 본 연구는 많은 국내 지자체들이 아동친화도시를 실현하기 위해 노력하고 있는 현 시점에서 지자체의 공공시설 조성경향을 파악하고 그 시설의 유형과 조성 내용을 정리하여 아동친화도시의 물리적 인프라 구현의 기반을 마련하고자 하였다. (연구방법) 이를 위해 빅카인즈(bigkinds)를 활용하여 국내에서 처음으로 아동친화도시인증을 받은 2013년부터 2020년까지의 신문기사와 그 안에서 언급된 356개의 시설을 추출하였다. 이를 주 이용대상과 지원속성에 따라 거점시설, 보육시설, 돌봄시설, 청소년활동시설, 놀이시설, 교육·체험시설, 문화·체육·의료시설로 분류하여 시기별 추이 및 유형별 내용을 분석하였다. (결과) 주요 연구결과를 보면 첫째, 공공시설 조성의 전반적인 흐름을 보면 아동친화도시인증을 받은 지자체가 증가한 2017년을 기점으로 시설 수도 증가하였다. 특히 청소년활동시설, 놀이시설에 대한 기사수가 증가하여 놀이와 여가활동에 대한 지원이 많아졌음을 알 수 있다. 둘째, 거점, 보육, 돌봄시설과 같은 복지관련 시설들은 정부의 정책적 방향과 아동친화도시를 구현하고자 하는 지자체의 방향과 부합하여 시설조성이 증가하였다고 볼 수 있다. 중앙정부와 지자체의 협력 하에 마을단위의 보육 및 돌봄체계가 확장되었음을 알 수 있다. 셋째, 청소년활동시설, 놀이시설은 지자체별로 다양한 형태로 등장을 하는데 시설의 명칭 또한 지자체별로 차별화를 하며 아동친화시설이 지자체 특화시설로 자리하고 있음을 알 수 있다. 넷째, 공공시설의 조성 방법에 있어서는 물리적 인프라의 확충을 위한 다양한 시도들이 있었다고 판단된다. 내외부의 유휴공간이 활용이 다양화되었으며 생활SOC를 복합화하면서 마을시설에 아동친화시설을 포함시켜 조성하고 있다. 이와 함께 아파트 관리동, 저층부를 활용하여 아동관련시설을 필수적으로 설치하는 방안들이 나타난다. (결론) 본 연구는 신문기사를 활용하여 최근 몇 년간 이루어진 아동친화도시의 전반적 경향을 정량적, 정성적으로 분석하였다는 점에서 의미를 가진다. 연구의 결과 시설의 유형이 다양하게 나타나고 있으며, 유휴시설의 활용 및 생활SOC복합화, 공동주택 공용공간 활용을 통한 양적 확충이 실행이 되고 있음 확인하였다. 본 연구에서 도출된 시설 유형들의 이용도 및 접근성에 대한 질적 연구가 이이었진다면 아동친화도시의 실제적 구현을 위한 근간이 풍부해질 것이라 기대한다. (Background and Purpose) There is a global consensus on the necessity of realizing a city that guarantees children's rights and improves the quality of their lives. Local governments in Korea have declared and practiced the creation of child-friendly cities, and since 2013, the number of local governments receiving child-friendly city certification is continuously increasing. This study aims to lay the groundwork for the realization of the physical infrastructure of a child-friendly city, by identifying trends in the creation of public facilities by local governments in Korea, and arranging the types and contents of the facilities systematically. (Method) This study used BigKinds, a news archive database, to collect newspaper articles, and extracted 356 facilities mentioned in articles from 2013, the first child-friendly city certification in Korea, to 2020. According to the main users and supporting attributes, these were classified as: anchor facilities, infant care facilities, elementary school students care facilities, youth activity facilities, play facilities, education/experience facilities, and cultural/sports/medical facilities. (Results) According to the main research results, first, the number of mentions of facilities in articles increased from 2017, when the number of local governments that received child-friendly city certification increased. Specifically, the number of articles on youth activity facilities and play facilities increased noticeably. Second, welfare-related facilities, such as anchor, infant care, and elementary school students care facilities, increased in line with the government's policy direction and the local government's efforts to realize a child-friendly city. Notably, the village-level care system has been expanded under the cooperation of the central and local governments. Third, youth activity facilities and play facilities appear in various forms by local government; the names of the facilities are also differentiated. Further, child-friendly facilities are positioned as specialized facilities of local governments. Fourth, various attempts have been made to expand the physical infrastructure in terms of the construction method of public facilities. The use of the idle space indoors and outdoors has been diversified, and child-friendly facilities are included in the village facilities, while the living SOC is complexed. At the same time, there are plans to install child-related facilities by using the apartment building management and the lower floors in apartment complexes. (Conclusions) This study is meaningful in that it quantitatively and qualitatively analyzed the overall trend of child-friendly cities in recent years using newspaper articles. The study found that the types of facilities are diverse, and quantitative expansion is being implemented through the use of idle facilities, living SOC complex, and the use of common space for apartment houses.

공동주택단지 보행자전용도로의 기능 확장과 개선방안 사례연구

김진희 ( Kim¸ Jinhee ),곽동화 ( Kwack¸ Dongwha ) 한국공간디자인학회 2021 한국공간디자인학회논문집 Vol.16 No.7

(연구배경 및 목적) 우리나라는 1960년대 산업화 이후 도시화가 진행되면서 양적위주의 공동주택 공급이 이루어졌다. 도시 공간과 배타적으로 존재하는 공동주택 단지는 외부와의 단절을 초래하였으며 이로 인해 공동주택 단지 외부공간을 구성하는 보행공간의 역할과 중요성은 간과되어졌다. 보행자전용도로는 통과나 이동을 위한 선적인 공간이기도 하지만 지역사회를 구성해 가는 최소단위로써 거주자들의 생활 기능 및 이웃과의 교류가 발생하는 면적인 공간으로 전환될 수 있는 공간이다. 이에 본 연구의 목적은 주거단지의 보행자전용도로 기능 확장을 검토하고 주거단지의 재생을 위한 보행자전용도로의 역할과 유효성을 제안하는 것에 있다. (연구방법) 연구대상은 주거단지 사이에 위치하며 인접 도시계획시설들과 적극적인 연계를 가진 보행자전용도로를 선정하였다. 연구의 공간적 범위는 인천광역시 남동구의 소래 휴먼시아 1,3단지 사이에 위치한 보행자전용도로로 폭은 약 9m, 길이는 약 334m이다. 연구의 진행은 첫째, 선행연구 및 문헌자료를 통해 보행공간에서 발생하는 활동과 보행환경의 질적 구성요소에 대해 고찰한다. 둘째, 이론적 고찰에 근거하여 분석의 틀을 작성하고 현장관찰을 통해 이용행태 관찰 및 보행환경 조사를 진행한다. 셋째, 분석 결과를 종합하여 보행자전용도로에 대한 개선안을 도출하고 방향을 제안한다. 넷째, 전문가 평가를 통해 개선방안에 대한 유효성을 검토한다. (결과) 보행자 활동분석과 보행환경의 질적 평가 결과, 현재의 보행자전용도로는 대부분 걷기와 같은 필수적활동의 행태를 보였고 이용가능성, 안심안전성, 쾌적성을 제외한 나머지 보행공간의 기능들은 낮은 척도를 보였다. 이와 같이 보행자전용도로가 개선해야할 점을 도출하였고, 공간계획의 방향에 맞게 개선안을 제안하였다. 유휴공간을 활용한 휴식 및 교류 공간 조성, 기존주호를 활용한 상업시설 및 문화교육시설 조성, 커뮤니티 시설의 연도형 배치를 통한 공공활동 및 문화프로그램 공간으로 조성하였다. (결론) 본 연구에서는 우리나라의 일정 규모 이상의 공동주택 단지에 일반적으로 건설되어지는 보행자전용도로를 커뮤니티가 공유하는 공유재의 기능으로 확장하여 지역사회와 교류할 수 있는 공간으로 기능을 극대화 하고자 하였다. 이와 같은 개선방향은 이웃과의 우호적인 관계형성 및 지역사회의 새로운 공동체를 형성하며 단절과 소외 등의 사회적 문제를 해결할 수 있다는 점에서 의의가 있으며 다른 보행자전용도로의 개선안으로써 참고가 될 것이다. (Background and Purpose) After industrialization in Korea in the 1960s, urbanization progressed and quantity-oriented apartments were supplied. Apartments, existing exclusively in an urban space, caused a disconnect from the outside world. Consequently, the role and importance of pedestrian spaces that constitute the exterior space of apartment housing were overlooked. The pedestrian-only roads are not only an axis space for passage or movement, but are also a space that can be converted into an area where residents' living functions and interaction with neighbors occur as the smallest unit constituting a local community. This study examines the functional expansion of pedestrian-only roads in residential complexes, proposing the role and effectiveness of pedestrian-only roads for the regeneration of residential complexes. (Method) The study subject selected was pedestrian-only roads between residential complexes, that actively linked to neighboring urban infrastructures. The spatial scope of the study are the pedestrian-only roads between Sorae Humansia Complex 1 and 3 in Namdong-gu, Incheon, with a width of about 9m and a length of about 334m. First, the qualitative components of the pedestrian environment and activities that occur in the pedestrian space are considered through previous studies and literature data. Second, the framework of the analysis is prepared based on theoretical consideration; additionally, behavior observation and pedestrian environment survey are conducted through field observation. Third, an improvement plan for pedestrian-only roads is derived and the direction is proposed by combining the analysis results. Fourth, the effectiveness of the improvement plan is examined through expert evaluation. (Results) Because of the analysis of pedestrian behavior and the qualitative evaluation of the pedestrian environment, most of the current pedestrian-only roads showed behaviors of essential activities, such as walking, and other functions of the pedestrian space―except usability, safety, and comfort ―were low. Thus, the improvement of pedestrian-only roads was derived, and the improvement plan was proposed following the direction of the spatial plan. Rest and community spaces were created using unused spaces; commercial and cultural education facilities were created using existing housing; and public activities and cultural program s were created through the corridor-type arrangement of community facilities. (Conclusions) In this study, the pedestrian-only road―generally constructed in apartment complexes of a certain size or larger in Korea, was expanded to function as public property shared by the community and to maximize its function as a space to interact with the local community. This improvement direction is meaningful in that it can form new communities with neighbors and solve social problems, such as disconnection and alienation. Further, it can be a reference for the improvement plans of other pedestrian-only roads.

스포츠윤리학을 위한 질적연구방법론

김진희 ( Kim¸ Jinhee ) 국민대학교 스포츠윤리연구소 2021 스포츠와 윤리 Vol.1 No.1

본 연구의 목적은 스포츠윤리학의 방법론 제공을 위해 질적연구방법론을 살펴보는 데 있다. 실증주의의 한계를 인정한 후 태동한 질적연구는 모든 학문분야에서 활용하고 있다는 점에서 스포츠윤리학의 학문적 토대를 공고히 하는데 질적연구가 방법적 활용을 넘어 연구방식, 초점, 스포츠윤리의 주요 질문들을 다양한 방식으로 탐구하는 통로가 되어줄 것이다. 이를 위해 2장에서는 스포츠윤리학에서 질적연구의 필요성을 논하고 탐구되어야 할 질적연구방법 여섯 가지를 스포츠윤리 연구 질문과 함께 제시한다. 3장에서는 스포츠윤리학자들이 질적연구방법을 수행할 때 필요한 자질과 역량을 자기연구 입장에서 논하며, 4장에서는 질적연구방법이 스포츠윤리학에 기여할 수 있는 방법론적, 학문적 및 실천적 시사점을 제시한다. The purpose of this study is to explore qualitative research methodologies to provide for sport ethics. Qualitative research, which began after acknowledging the limitations of positivism is used in all academic fields, so qualitative research will be a channel to explore major questions of research methods, focus, and sport ethics. Chapter 2 suggests six qualitative research methods to be explored in sport ethics. Chapter 3 discusses the qualities and capabilities needed for sports ethic researchers to conduct qualitative research methods from a self-research perspective. Chapter 4 explains academic implications that qualitative research methods can contribute to sport ethics.

아동병원 간호사의 의사소통능력, 자기효능감이 간호사-환아부모 파트너십에 미치는 영향

김진희 ( Kim¸ Jinhee ),이한나 ( Lee¸ Hanna ) 경희대학교 동서간호학연구소 2021 동서간호학연구지 Vol.27 No.2

Purpose: This study aimed to identify the influence of communication competence and self-efficacy of nurses at children’s hospitals on the nurse-parent partnership. Methods: Data were collected by surveying (from July 4th to August 4th, 2019) 162 nurses who had 6 or more months of experience across 15 children’s hospitals in G City and B Metropolitan City. Using SPSS 23.0 for Windows for data analysis, t-tests, analysis of variance, Bonferroni tests, Pearson’s correlation coefficient, and multiple regression analysis were performed. Results: The nurse-parent partnership showed significantly positive correlations with nurses’ communication competence and with self-efficacy. There was a significantly positive correlation between nurses’ communication competence and self-efficacy. The factors influencing the nurse-parent partnership were nurses’ communication competence, job satisfaction, and self-efficacy; the total explanatory power of these variables was 47.0%. Conclusion: Since the communication competence of nurses at children's hospitals was identified as a major factor influencing the nurse-parent partnership, it may be meaningful to conduct basic research aimed at developing strategies to improve this partnership at children’s hospitals.

Neurotoxicant (fenitrothion) alters superoxide dismutase, catalase, and peroxidase activities in Chironomus riparius Mg.

Jinhee Choi(Jinhee Choi) 한국환경성돌연변이발암원학회 2001 한국환경성돌연변이·발암원학회지 Vol.21 No.2

Effects of exposure to a neurotoxicant, fenitrothion on antioxidant enzyme activities in Chironomus riparius Mg. (Diptera, Chironomidae) larvae were evaluated under laboratory conditions. Exposure to this chemical led to an increase of cupper, zinc type superoxide dismutase and manganese type superoxide dismutase activities and to a decrease of glutathion peroxidase activity. An activation of catalase was observed in the larvae exposed to high fenitrothion concentration. The response of superoxide dismutase was rapid and sensitive to low chemical concentrations, but changes in catalase, total peroxidase and glutathion peroxidase were less sensitive. In this study, antioxidant enzyme activities in Chironomus riparius larvae were identified as pertinent biomarkers for environmental monitoring.