SH2D4A regulates cell proliferation via the ERα/PLC-γ/PKC pathway

( Ting Ting Li ),( Wei Li ),( Jing Yu Lu ),( Hong Liu ),( Ying Hui Li ),( Yan Yan Zhao ) 생화학분자생물학회 2009 BMB Reports Vol.42 No.8

Data Cleaning Utilizing Ontology Tool

Jing Ting Wong,Jer Lang Hong 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.7

Recent advancement in Internet Technologies has made web browsing increasingly easy and user friendly. From the traditional method of desktop web browsing and the birth of dial up modem connection, users nowadays are able to enjoy a fast and reliable web browsing via high speed wireless Internet connection and portable mobile devices. Browsing a web has become much easier with the state of the art search engines such as Google, which provide much functionalities which could make browsing easier such as improved crawler, easy to use search interface, web personlization, Web 3.0 support and integration and many more. In order to build a robust and reliable search engine, the developer needs to integrate all the data and present them in a meaningful format for user’s viewing convenience. Integrating these data is a tedious task as data usually occur in numerous format, and layout. Furthermore, web developers usually present the data content in various languages of their choice, which made the processing of these data increasingly difficult. There is also no standard convention to represent the data format and even a standardize rule to process this data has not been developed. To resolve this issue, researchers develop data extractor which could effectively extract data from web sources, tabulate them, and used it for further processing. However, not all data are correctly extracted, they may either missed certain valuable information or contain additional unnecessary information. In the case of unnecessary information, researchers use a cleaning method to remove them such that the data extracted are free of errors. Removing these data is important as unnecessary information may affect the accuracy of subsequent extractor tools, hence may eventually prevent the tool from performing its task efficiently. In this research proposal, we embark on a data cleaning tool to clean data using ontology tools. Experimental results show that our tool is highly efficient in data cleaning and is able to outperform existing state of the art tools.

Secret Key Generation Using Reciprocity in Ultra-wideband Outdoor Wireless Channels

( Jing Jing Huang ),( Ting Jiang ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.2

To investigate schemes of secret key generation from Ultra-wideband (UWB) channel, we study a statistical characterization of UWB outdoor channel for a campus playground scenario based on extensive measurements. Moreover, an efficient secret key generation mechanism exploiting multipath relative delay is developed, and verification of this algorithm is conducted in UWB Line-of-sight (LOS) outdoor channels. For the first time, we compare key-mismatch probability of UWB indoor and outdoor environments. Simulation results demonstrate that the number of multipath proportionally affects key generation rate and key-mismatch probability. In comparison to the conventional method using received signal strength (RSS) as a common random source, our mechanism achieves better performance in terms of common secret bit generation. Simultaneously, security analysis indicates that the proposed scheme can still guarantee security even in the sparse outdoor physical environment free of many reflectors.

Secret Key Generation from Common Randomness over Ultra-wideband Wireless Channels

( Jing Jing Huang ),( Ting Jiang ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.10

We develop a secret key generation scheme using phase estimation in ultra-wideband (UWB) wireless fading channels. Based on the reciprocity theorem, two terminals extract the phase of the channel as a common random source to generate secret bits. Moreover, we study the secret key rate by a pair of nodes observing correlated sources and communicating to achieve secret key agreement over public communication channels. As our main results, we establish a more practical upper bound from Cramer-Rao bound (CRB) and compare it with a universally theoretical upper bound on the shared maximum key rate from mutual information of correlated random sources. Derivation and numerical examples are presented to demonstrate the bound. Simulation studies are also provided to validate feasibility and efficiency of the proposed scheme.

Long Non-coding RNAs are Differentially Expressed in Hepatocellular Carcinoma Cell Lines with Differing Metastatic Potential

Fang, Ting-Ting,Sun, Xiao-Jing,Chen, Jie,Zhao, Yan,Sun, Rui-Xia,Ren, Ning,Liu, Bin-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Background: Metastasis is a major reason for poor prognosis in patients with cancer, including hepatocellular carcinoma (HCC). A salient feature is the ability of cancer cells to colonize different organs. Long non-coding RNAs (lncRNAs) play important roles in numerous cellular processes, including metastasis. Materials and Methods: In this study, the lncRNA expression profiles of two HCC cell lines, one with high potential for metastasis to the lung (HCCLM3) and the other to lymph nodes (HCCLYM-H2) were assessed using the Arraystar Human LncRNA Array v2.0, which contains 33,045 lncRNAs and 30,215 mRNAs. Coding-non-coding gene co-expression (CNC) networks were constructed and gene set enrichment analysis (GSEA) was performed to identify lncRNAs with potential functions in organ-specific metastasis. Levels of two representative lncRNAs and one representative mRNA, RP5-1014O16.1, lincRNA-TSPAN8 and TSPAN8, were further detected in HCC cell lines with differing metastasis potential by qRT-PCR. Results: Using microarray data, we identified 1,482 lncRNAs and 1,629 mRNAs that were differentially expressed (${\geq}1.5$ fold-change) between the two HCC cell lines. The most upregulated lncRNAs in H2 were RP11-672F9.1, RP5-1014O16.1, and RP11-501G6.1, while the most downregulated ones were lincRNA-TSPAN8, lincRNA-CALCA, C14orf132, NCRNA00173, and CR613944. The most upregulated mRNAs in H2 were C15orf48, PSG2, and PSG8, while the most downregulated ones were CALCB, CD81, CD24, TSPAN8, and SOST. Among them, lincRNA-TSPAN8 and TSPAN8 were found highly expressed in high lung metastatic potential HCC cells, while lowly expressed in no or low lung metastatic potential HCC cells. RP5-1014O16.1 was highly expressed in high lymphatic metastatic potential HCC cell lines, while lowly expressed in no lymphatic metastatic potential HCC cell lines. Conclusions: We provide the first detailed description of lncRNA expression profiles related to organ-specific metastasis in HCC. We demonstrated that a large number of lncRNAs may play important roles in driving HCC cells to metastasize to different sites; these lncRNAs may provide novel molecular biomarkers and offer a new basis for combating metastasis in HCC cases.

现代书法艺术性的初步探索

형정(Jing Ting) 한국서예학회 2023 서예학연구 Vol.42 No.-

현대서예에 관해 최근 몇 년 동안 다양한 논의가 진행되어 왔다. 현대서예는 전통서예의 심미관에 위배되며, 서양의 추상화 예술이론을 완전히 답습하였다는 등의 이유로 서예가 아니라는 등의 반대 의견이 발생하였다. 그러나 현대서예는 서예일 뿐만 아니라 예술성이 높은 서예이다. 전통에 뿌리를 두고 있으며, 서양 예술이론을 그대로 답습하여 접목한 것이 아니다. 서예가들은 민간서예를 통해 독특한 예술언어의 서예 풍격을 생성하는 것이다. 본 논문은 현대서예가 전통서예의 서사성과 대립 통일 규율에 대한 계승이자 혁신이라는 관점에 입각하여 연구와 논술을 전개하고, 수묵예술과 문자예술의 양면에서 현대서예의 실천성과를 분석했다. 제3장에서는 동양 전통 수묵예술의 영향을 받은 서양화가들의 작품에서 동양 수묵적 요소가 어떻게 구현되었는지를 분석했다. 제4장에서는 공간 예술 실천과 서사 예술 실천의 두 가지 측면에서 현대서예의 혁신점을 분석하고 실증하였다. 특히 혁신적인 현대서예 작품을 통해 자형적 과장성, 자기정신적 표현성, 서사과정의 표현성 등의 예술적 특징을 분석하고 현대서예의 발전방향과 존재 의의를 확인하였다. The topic of modern calligraphy has been a heated topic of discussion in recent years. Modern calligraphy goes against the traditional aesthetic of calligraphy and is seen as simply copying Western abstract art theory. There are many opposing views that claim modern calligraphy is not true calligraphy. However, modern calligraphy is not only calligraphy, but also a highly artistic form of calligraphy. Modern calligraphy is rooted in tradition and not simply copying Western art theory and forcing it into calligraphy. Calligraphers have developed a unique artistic language through folk calligraphy. This article focuses on the study and discussion of the view that modern calligraphy is the inheritance and innovation of the writing nature and the principle of dialectical unity in traditional calligraphy. The practice achievements of modern calligraphy are analyzed from two aspects: ink art and calligraphy art. The chapter on ink art mainly refers to Western painters who are influenced by traditional Eastern ink art elements and embody them in their works. The chapter on calligraphy art analyzes and demonstrates the innovations of modern calligraphy from two aspects: spatial art practice and writing art practice. By analyzing innovative modern calligraphy works, the artistic features of exaggerated letterforms, expressive self-spirit, and the expressive process of writing are revealed. The research concludes by recognizing the development direction and significance of modern calligraphy. 关于现代书法,是近些年一直讨论非常火热的话题。现代书法违背了传统书法的审美观,现代书法完全照搬西方的抽象画艺术理论,现代书法不是书法等等反对观点层出不穷。现代书法不仅是书法,而且是艺术性较高的书法。现代书法植根于传统,并不是完全照搬西方艺术理论,生搬硬套在书法上,书家们通过民间书法,生发出独特艺术语言的书法风格。本文立足于现代书法是对传统书法书写性与对立统一规律的继承与创新这一观点展开研究与论述,从水墨艺术和文字艺术两方面分析现代书法的实践成果,水墨艺术这一章节主要是指受东方的传统水墨艺术元素影响的西方画家在作品中,对东方水墨元素的体现;文字艺术这一章节从空间艺术实践和书写艺术实践两个方面分析论证现代书法的创新之处,通过创新的现代书法作品分析出现代书法的具有字形的夸张性、自我精神的表现性和书写过程的表现性的艺术特征,通过研究认识到现代书法发展方向与存在的意义。

The Gender-Sensitive Social Risk Factors for Internet Addiction in College Undergraduate Students

Xia Lin,Jing-yan Gu,Wan-jun Guo,Ya-jing Meng,Hui-yao Wang,Xiao-jing Li,Wei Deng,Lian-sheng Zhao,Xiao-hong Ma,Ming-li Li,Ting Chen,S,K,Cheng,Tao Li 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.7

Objective The current study aims to explore precipitating and social risk factors for internet addiction (IA) in university undergraduate students, and to provide evidence for interventions and the early prevention of IA in different genders. Methods Four thousand eight hundred and fifty-eight college sophomores completed an online survey on their internet use-related behaviours and social risk factors. Results We found that more male (8.3%) than female students (5.4%) had moderate and severe IA. The main online activity in the moderate and severe IA groups was online gaming in males and online streaming in females. Roommates engaging in similar internetbased entertainment was a risk factor of IA only for males, while not being in a romantic relationship was a risk factor of IA for females only. Infatuation with the internet before college and adjustment problems for college life were shared risk factors for both genders in the mild and moderate IA groups. Conclusion IA was a common phenomenon in college students with shared and unique precipitating and social risk factors in males and females. The gender-sensitive risk factors for IA warranted earlier and individualized intervention and prevention strategies for IA in this population.

Photo-induced antifouling polyvinylidene fluoride ultrafiltration membrane driven by weak visible light

Ting Wang,Ling-li Jiang,Lu-lu Huang,Li-guang Wu,Chun-juan Li,Jing Cai 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.89 No.-

To enhance the performance of ultrafiltration membranes, a polyvinylidenefluoride (PVDF) blendingmembrane with photo-induced antifouling performance was fabricated. La3+- and Yb3+-doped titaniumdioxide-reduced graphene oxide (TiO2-RGO) composites were initially prepared by adsorption-phasesynthesis coupled with solvothermal reduction. The doped TiO2-RGO composites were then blendedwith the PVDF materials. The results showed that adding well-distributed, doped, and hydrophilic TiO2-RGO improved the pore structures and surface polarity of the blending membranes, thus improving theirpermeation and antifouling performance. After addition of doped TiO2-RGO with photocatalytic activity,the antifouling performance of the resulting blending membranes increased under weak visible-lightirradiation. The agglomerated doped TiO2-RGO in the polymeric matrix reduced the hydrophilicity andporosity of the resulting membranes, thereby decreasing their water permeability and antifoulingperformance. Solvothermal reduction through ethylene glycol also improved the photocatalytic activityof Yb-doped TiO2-RGO and enhanced the affinity between doped TiO2-RGO and PVDF. These two effectssimultaneously increased the water permeability and photo-induced antifouling performance of theblending membranes. Theflux recovery rate of the blending membranes containing Yb-doped TiO2-RGOtreated by ethylene glycol exceeded 69% after illumination. In particular, theflux recovery rate ofmembranes reached about 96% after illumination coupling with washing.

An Investigation on the Density Wave Instability of High Pressure Steam-Water Two-Phase Flow in Vertical Parallel Pipes

Ting Kuan Chen,Jiangang Jing 대한기계학회 1998 Heat transter conference Vol.2 No.1

Tumor Markers for Diagnosis, Monitoring of Recurrence and Prognosis in Patients with Upper Gastrointestinal Tract Cancer

Jing, Jie-Xian,Wang, Yan,Xu, Xiao-Qin,Sun, Ting,Tian, Bao-Guo,Du, Li-Li,Zhao, Xian-Wen,Han, Cun-Zhi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

To evaluate the value of combined detection of serum CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS for the clinical diagnosis of upper gastrointestinal tract (GIT) cancer and to analyze the efficacy of these tumor markers (TMs) in evaluating curative effects and prognosis. A total of 573 patients with upper GIT cancer between January 2004 and December 2007 were enrolled in this study. Serum levels of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were examined preoperatively and every 3 months postoperatively by ELISA. The sensitivity of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were 26.8%, 36.2%, 42.9%, 2.84%, 25.4%, 34.6%, 34.2% and 30.9%, respectively. The combined detection of CEA+CA199+CA242+CA724 had higher sensitivity and specificity in gastric cancer (GC) and cardiac cancer, while CEA+CA199+CA242+SCC was the best combination of diagnosis for esophageal cancer (EC). Elevation of preoperative CEA, CA19-9 and CA24-2, SCC and CA72-4 was significantly associated with pathological types (p<0.05) and TNM staging (p<0.05). Correlation analysis showed that CA24-2 was significantly correlated with CA19-9 (r=0.810, p<0.001). The levels of CEA, CA19-9, CA24-2, CA72-4 and SCC decreased obviously 3 months after operations. When metastasis and recurrence occurred, the levels of TMs significantly increased. On multivariate analysis, high preoperative CA72-4, CA24-2 and SCC served as prognostic factors for cardiac carcinoma, GC and EC, respectively. combined detection of CEA+CA199+CA242+SCC proved to be the most economic and practical strategy in diagnosis of EC; CEA+CA199+CA242+CA724 proved to be a better evaluation indicator for cardiac cancer and GC. CEA and CA19-9, CA24-2, CA72-4 and SCC, examined postoperatively during follow-up, were useful to find early tumor recurrence and metastasis, and evaluate prognosis. AFP, TPA and TPS have no significant value in diagnosis of patients with upper GIT cancer.