Young-Ki Kim

Sun-young Park,Youngjae Lee,Jinyoung Song,Seok-ho Jeon,Ji-yoon Jeong,강병택,강지훈,장진화,장동우 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.3

Signalment: An 8-month-old female Alaskan malamute was presented for progressive cluster seizure disorder. Results: There were no abnormalities on neurological examination, survey radiographs, or blood analysis. Magnetic resonance (MR) imaging and computed tomography revealed extension of the olfactory bulb and frontal lobe into the nasal cavity. They also confirmed abnormal anatomy of the nasal turbinates within the rostral part of the nasal cavity and the absence of a cribriform plate. On T2-weighted and fluid-attenuated inversion recovery images, the herniated brain showed heterogeneous and hyperintense signals consistent with intraparenchymal edema. Transverse MR images showed brain herniation into the right frontal cavity and an asymmetrical lateral ventricle because of a left midline shift. On contrast-enhanced MR images, the protruding brain parenchyma was mildly enhanced. Ethmoidal encephalocele was suspected as the final diagnosis. Despite symptomatic treatment, the dog continued to exhibit seizures and was euthanized. Clinical relevance: Ethmoidal encephalocele is a rare disease in dogs. However, it could be considered as a cause of seizure in young dogs.

Production and Characterization of Enzymes Involved in Chitin Catabolic Cascade from a Bacterial Strain Isolated from Soil

( Ji Hyun Lee ),( Jeong In Lee ),( So Yeon Park ),( Yoo Kyeong Jang ),( You Bin Lim ),( Hye Yoon Lee ),( Young Min Jung ),( Hae Chang Lee ),( Jong Hwa Lee ),( Shaheen Amna ),( Jae Kweon Park ) 한국키틴키토산학회 2019 한국키틴키토산학회지 Vol.24 No.1

The present study was aimed to isolate the bacteria producing chitinolytic enzymes including chitin deacetylase (CDA) from soil origin. About 24 bacteria were screened for their chitinolytic enzymes producing ability on the basis of colloidal chitin. Amongst one of the most potent isolates designated to JI-02 was further selected as the most prominent chitinolytic and CDAlike enzyme (CDA-X) producer based on the ability of deacetylation of an artificial substrate pNP-acetamilide. The maximum production of CDA-X in crude enzyme from JI-02 was observed in the presence of 1% colloidal chitin at 37°C and pH 6.4 after 120 h of incubation. Potent enzyme activity of CDA-X was determined toward pNP-acetamilide, demonstrating that optimal pH, temperature and ionic strength of the CDA-X were assessed to be 7.0, 52°C and 125 mM, respectively. Unexpectedly, Nacetylglucosamine (GlcNAc) was not fully converted by the action of CDA-X to glucosamine (GlcN) under the established conditions. Further study on enzyme activity toward chitin-oligosaccharides consisting of multi-N-acetylglucosamine (GlcNAc)n, n=2-5 may be necessary to elucidate the mode of action which requires the minimum size of (GlcNAc)n. However, our data suggest that CDA-X can convert chitin to chitosan with the maximum yield of approximately 0.08g/L during the fermentation of the strain in the presence of chitin. Furthermore, we found that crude enzyme showed the significant chitosanolytic activity. Taken together, our data suggest that the strain JI-02 may be a potential candidate as a particular strain for better understating of chitin catabolic pathway.

고감도 Ames test(microsuspension assay)와 임파구 소핵시험법을 이용한 변이원성에 관한 조사 연구

안지영,김해준,윤인재,성영자,김영환,장영철 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.3

In order to evaluate the mutagenic effects of extractable indoor air pollutants (organic matters), we measured the mutagenic activities by sensitive microsuspension Ames test using new tester strains (YG 1024 and YG 1029). And additionally to evaluate the mutagenic effects on vital cell, we examined the frequencies of micronucleus appearing in lymphocytes from dye handling workers and controls. This study was conducted from Jan. to May, 1995. The extractable indoor air pollutants were collected by low volume air sampler in a general office room and 3 of dye handling factories. And the environment of general office room divided into 3 different groups according to the type of room heaters. To determine the frequencies of micronucleus appearing in lymphocytes, we sampled peripheral venous blood from 20 of dye handling workers and 20 of controls, and cultured, and then examined the lymphocytes. The results obtained were as follows: 1. The indirect mutagenic activities of extractable organic matters from suspended particulates collected in a general office room were higher than the direct one. 2. The strain YG 1024 was the most sensitive, and the increasing order of test strains that showed higher number of revertant were YG 1024, YG 1029, TA 100, TA 98. 3. In the general office room, the room using kerosene heater showed the highest mutagenecity, and the next was buthan gas heater, and non-heating room in order. 4. The mutagenic effects of suspended particulates in dye handling factories on the strain YG 1024 was 1.2 times higher than YG 1029. 5. The frequencies of micronucleus appearing in lymphocyte of the circulating blood of dye handling workers and the control were 5.65±2.97‰ and 4.65±0.97‰, respectively. And the difference was statistically significant.

인터넷 중독 고위험 청소년의 성별에 따른 임상적, 정신병리적 특성

이지윤(Ji Yoon Lee),권준근(Jun-Gun Kwon),이준영(Jun-Young Lee),정희연(Hee Yeon Jung),손보경(Bo Kyung Sohn),최삼욱(Sam Wook Choi),김대진(Dai Jin Kim),최정석(Jung-Seok Choi) 한국중독정신의학회 2016 중독정신의학 Vol.20 No.1

Objectives : Most previous studies of Internet addiction (IA) have been performed on males, and little is known about gen-der differences in IA. We examined gender differences in the clinical and psychopathological features related to high-risk for IA among adolescents. Methods : 714 (male : N=389 ; fe-male : N=325) have reported questionnaires as follows ; 1) clinical and psychopathological features (depression, anxiety, Attention Deficit Hyperactivity Disorder (ADHD) symptoms, Smartphone addiction, impulsivity, behavioral inhibition and approach systems, state-trait anger, aggression, beliefs about aggression, and resilience) 2) Internet and Smartphone usage patterns. In 691 who completed the Young’s Internet Addiction Test (YIAT), A total of 487 adolescents were classified into the normal Internet use group, with YIAT scores of 20-39 (male :N=232 ; female : N=255) and 204 adolescents were classified into high-risk for IA group (male : N=144 ; female : N=60). Results : Most factors described above predicted high-risk for IA in male and female adolescents. Especially, the present study found that psychological resilience had negative association with possibility of IA in female, while cognitive impulsivity and hostile aggression were associated with possibility of IA in male adolescents. Conclusion : This study found gender-re-lated features in adolescents at high-risk for IA. Thus, gender-specific strategies are needed to maximize prevention and treatment effectiveness of IA.

딥러닝을 활용한 전략물자 판정 지원도구 개발에 대한 연구

조재영(Jae-Young Cho),윤지원(Ji-Won Yoon) 한국정보보호학회 2020 정보보호학회논문지 Vol.30 No.6

전략물자관리 제도의 이행 확산에 따라 전략물자 판정의 중요성이 높아지고 있으나 전략물자 제도를 처음 접하는 수출기업은 전략물자의 개념을 이해하기 쉽지 않고, 전략물자를 통제하는 기준이 다양하여 전략물자 판정에 어려움이 따른다. 본 논문에서는 전략물자 제도를 처음 접하는 기업이나 전략물자 판정시스템 이용자에게 진입장벽을 낮추어 판정이라는 과정을 쉽게 접근할 수 있는 방법을 제안한다. 이용자가 전략물자 판정이라는 절차를 매뉴얼이나 카탈로그의 제공만으로 판정결과를 확인할 수 있게 된다면, 전략물자 판정 방법과 절차에 보다 편리하고 쉽게 다가설수 있을 것이다. 본 연구 목적을 달성하기 위해 이미지 인식 및 분류에서 연구되고 있는 딥러닝과 OCR(광학문자판독) 기술을 활용하고, 전략물자 판정 지원도구에 대한 개발과 연구를 통하여 우리 기업의 전략물자 판정에 도움이 되는 정보를 제공한다. As the implementation of export controls is spreading, the importance of classifying strategic items is increasing, but Korean export companies that are new to export controls are not able to understand the concept of strategic items, and it is difficult to classifying strategic items due to various criteria for controlling strategic items. In this paper, we propose a method that can easily approach the process of classification by lowering the barrier to entry for users who are new to export controls or users who are using classification of strategic items. If the user can confirm the decision result by providing a manual or a catalog for the procedure of classifying strategic items, it will be more convenient and easy to approach the method and procedure for classfying strategic items. In order to achieve the purpose of this study, it utilizes deep learning, which are being studied in image recognition and classification, and OCR(optical character reader) technology. And through the research and development of the support tool, we provide information that is helpful for the classification of strategic items to our companies.

연구논문 : 대학생들의 인터넷 중독에 영향을 미치는 요인에 대한 연구

권미영 ( Mi Young Kwon ),황지영 ( Ji Young Hwang ),정혜윤 ( Hye Yoon Jung ),송시형 ( Shi Hyeong Song ) 극동대학교 사회복지연구소 2013 글로벌사회복지연구 Vol.3 No.2

본 논문의 목적은 대학생의 인터넷 중독에 영향을 주는 요인에 대한 분석을 통해 대학생의 정신건강을 위한 공적프로그램 도입에 대한 함의를 제공하는 것이다. 분석자료는 을지대학교 강남 을지 병원 중독연구소에서 대학생 453명을 대상으로한 설문지이다. 설문조사에 사용된 설문지는 인터넷 중독을 측정하는 인터넷 중독 척도(Young척도), 불안을 측정하는 불안척도(STAI)와 우울을 측정하는 Beck의 우울척도(BDI)로 구성되었다. 분석결과 첫째, 연령 및 학년은 인터넷 중독에 유의미한 영향을 미쳤다. 둘째, 나이가 어릴수록, 학년이 낮을수록 불안과 우울에 빠지기 쉬웠다. 셋째, 무엇보다 불안이 대학생의 인터넷 중독에 가장 큰 영향을 미치는 요인이었다. The purpose of this research to suggest implications on introduction of public-program for college students` mental health through analysing the factors which impact on internet addiction of college students. The analysing data is questionnaire intended to 453 college students in Kang- Nam Eulji hospital addiction institute. The questionnaire consisted of internet addiction scale (Young-scale), anxiety scale (STAI) and depression scale (BDI). This study reveals three main findings. Firstly, age and grade have an effect on internet addiction. Second, the younger, the lower grade, they are likely to be depressed and anxiety. Third, most of all, the anxiety has the most effect on internet addiction of college students.

심한 골병변으로 발현된 기능성 낭종성 부갑상선 선종

전숙,김영희,박지영,고관표,박철영,김덕윤,우정택,김성운,김진우,김영설,고석환 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.2

낭종성 부갑상선 선종과 심한 골병변을 동반한 부갑상선 기능항진증은 매우 드문 질환으로서, 저자들은 양측 고관절의 통증을 초기 주소로 내원한 환자에서 고칼슘혈증과 부갑상선 호르몬 증가, 골병변의 방사선적 소견을 통해 부갑상선 기능항진증을 진단하고, 경부 초음파와 컴퓨터 단층 촬영, 부갑상선 스캔검사 및 수술중 부갑상선 낭종액 검사 등을 통해 기능성 부갑상선 낭종의 한 종류인 낭종성 부갑상선 선종을 진단하고 수술적 제거를 통하여 정상화된 1예를 경험하였다. A cystic parathyroid adenoma is rare. A case of primary hyperparathyroidism, with the cystic formation of a parathyroid adenoma and a severe bony lesion, is reported. A 52-year-old male was admitted due to pain in both hips and for evaluation of hypercalcemia. The plasma level of the intact parathyroid hormone (iPTH) was elevated to 1424 pg/mL. Ultrasonography and the computed tomography revealed a parathyroid cyst on the left thyroid lower pole. Parathyroid scintigraphy detected a parathyroid adenoma. A radiograph showed a subperiosteal bone resorption on the phalanges, and a brown tumor (osteitis fibrosa cystica) on the femur shaft was noted. A surgical excision of the parathyroid adenoma was performed. The PTH level in the cystic fluid was increased. A histological examination confirmed a cystic parathyroid adenoma. The PTH level was normalized after the operation (J Kor SOC Endocrinol 18:214-220, 2003).

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

초등학교 체육특기적성교육 참여가 체육수업 및 생활체육 인식에 미치는 영향

윤지영 이화여자대학교 교육대학원 2005 이화교육논총 Vol.15 No.-

The purpose of this study was to investigate the influence of specialty and aptitude program on recognizing the importance of physical education class as well as life-time sports. Elementary school students were recruited in the study, and the results of the study are expected to add more knowledge on specialty and aptitude training. A multiple method research technique was used in this study. By implementing both quantitative and qualitative methodology, the researcher collected data by administering questionnaires and conducting interviews. A multi-stage stratified cluster random sampling technique was used in this study. The researcher selected eight elementary schools in Seoul, Korea, and the subjects were fourth to sixth grade students in those schools. Eight hundred questionnaires were distributed, and 752 of them were used in this study. Using the SPSS program, frequency test, T test, and one-way analysis of variance were conducted. In addition, the researcher conducted interviews with eight students from two different schools. Interview data were tape recorded, and the researcher took field notes. The following are conclusions of this study. It was found that parents who frequently participate in physical activities put more importance on specialty and aptitude program. In addition, students who are currently in the program in element, level had positive attitudes towards continuing the program when they advance to middle school and high school. Most students were satisfied with the program Physical fitness, socialization, enjoyment, and leisure participation were perceived benefits among the students. This study found that students who are in the specialty and aptitude program recognized the importance of the physical education class including its objective, contents, method, and evaluation. It was implied that participating in the program would allow more opportunities to participate in physical activities than those who are not in the program. As a result, students with increased opportunities will be more interested in physical activities that in turn will enhance their physical fitness. This study found that students who are in the specialty and aptitude program recognized the importance of the life-time sports including physical development, psychological stability, socialization, and leisure participation. In addition, those who are currently in the program had more preference towards the program. They were also interested in participating in various sport activities that they have not played before. Some students were interested in pursuing career in professional sports, and the majority of students indicated their intention for ongoing participation. In conclusion, specialty and aptitude program in elementary school has positive influence on physical education classes, and people could achieve better quality of life through continuing to participate in sports. It is important to develop more specialty and aptitude programs in different levels, and more researchers on finding what students are really interested in is also needed.

증권시장에서 판매원 윤리의식의 결정요인

지성구,이감용,윤영진 한국유통정보학회 2001 유통정보학회지 Vol.4 No.1

This research addresses the determinants of salespeople's ethical awareness(SEA) in stock market. The suggested model include several factors such as environmental uncertainty(volatility and diversity), customer orientation, ethical climate and perception of the ethical awareness of supervisor. Some hypotheses that show the relationship between SEA and the factors are suggested. To attain these objective of this research, samples from salespeople were collected. For the analysis of data, reliability test, validity test, correlation analysis, multiple regression analysis and frequency analysis were used with SPSS WIN package. the results show that environmental volatility, customer orientation(3 factor, 1 factor), organization's ethical climate, affect SEA, however, environmental diversity and customer orientation(2 factor, 4 factor) don't work. And, as hypothesized, SEA generally had positive impacts on customer relationship quality(customer's trust and satisfaction).