납석을 이용한 β - spodumene의 합성

박정현,김경희,심덕녀 연세대학교 산업기술연구소 1994 논문집 Vol.26 No.1

β-spodumene was synthesized using pyrophyllite and Li₂CO₃Properties of pyrophyllite were characterized and analyzed. Cooling process was varied to know the effect on the phase formation. One was quenching and the other was cooling in the furnace. Li₂O mole content was varied from 0.95 to 1.05. Heat-treated pyrophyllite and Li₂CO₃were mixed, formed and calcined to synthesize of β- spodumene with better properties. β-spodumene was formed when quenched but when cooled slowly in the furnace two phases of β-spodumene and petalite were formed. The phases formed after cooling didn't depend on the Li₂O mole content and calcination temperature. In this experiment calcination temperature of 1050∼1100℃ and 1 mole addition of Li₂O were the optimum condition to synthesize β-spondumene. It was observed that heat treatment of pyrophyllite resulted in better properties of β-spodumene than that synthesized from the raw pyrophyllite.

여성 향유층의 존재와 조선후기 몽유록

김정녀 ( Jeong Nyo Kim ) 반교어문학회 2004 泮橋語文硏究 Vol.16 No.-

< 내성지 > 의 양식적 특징과 그 의미

김정녀 ( Jeong Nyo Kim ) 우리한문학회 2001 漢文學報 Vol.5 No.-

Wernicke’s Encephalopathy and Peripheral Polyneuropathy Developed during Long Term Metronidazole Therapy in a Patient with a Brain Abscess- A Case Report -

Nyo Kyung Park,권범선,박진우,이호준,류기형,Sang Wuk Jeong,Sang Mi Noh 대한재활의학회 2011 Annals of Rehabilitation Medicine Vol.35 No.1

Metronidazole can induce serious neurologic problems including peripheral neuropathy, seizures, and encephalopathy. We examined a patient with acute Wernicke’s encephalopathy and peripheral polyneuropathy that had developed after prolonged metronidazole therapy without a history of chronic alcoholism or poor nutritional intake. The 68-year-old man had been hospitalized for a brain abscess and was treated for 10 weeks with metronidazole (2 grams per day). This patient, who showed symptoms of numbness and tingling in the legs, was referred for electromyography (EMG) and was diagnosed with peripheral polyneuropathy. A few days later, he developed sudden ataxia, dizziness, and diplopia. The neurologic examination revealed nystagmus and ophthalmoplegia, and the FLAIR brain MRI showed symmetrical high signal intensity lesions in the cerebellar dentate nucleus, midbrain, tegmentum around the periaqueductal gray matter, and tectum. After administering intravenous thiamine and stopping the metronidazole therapy, he recovered from the ophthalmoplegia and ataxia. Brain MR showed complete recovery within 3 weeks; however the EMG remained abnormal for a further 6 months, although the symptoms were almost completely resolved by this time.

< 만옹몽유록 > 연구

김정녀 한국고소설학회 2000 古小說 硏究 Vol.9 No.1

This paper aimed at introducing <Manongmongyurok>, written by Yoon, Chi-Bang(1794∼1877) at 1869. For this purpose I researched Yoon's life and the background of writing. This kind of research is helpful for understanding the phrase of Mongyu mode and the characteristics of Mongyurok in 19th century. <Manongmongyurok>, is appeared in 『Manongyugo』 volume one. The character of this Mongyurok, named Bulonjai, travels around the five famous mountains in China. After traveling mountains, he looks around the places of scenic beauty and historic interest. Finally arriving at Tabak mountain, he woke up the dream of traveling. This work is very important for us to understand the traits of 19th century Mongyurok. Yoon, as a typical intelligent, spent most of his time reading, writing and research about Confucianism. When he moved to Goangtan is the time, we have to much more pay attention to his life concerning the work than other time. When he lived in Goangtan, he experienced a lot of difficulty and wrote <Manongmongyurok>. At this time Yoon thought himself as none. So he had to create a special character who could look around the China and realize self-existence. Yoon want to travel many famous historical places for the purpose of following after the great man in history. This hope made Yoon create the work. <Manongmongyurok> made choice of different narration structure ; the plot of work mainly depends on traveling mountains and livers. It means the 19th century Mongyurok differentiate from the former period narration structure which generally consisted of 'disposition - debation - the party of poems'. The writers of Mongyurok in 19th century partly took in former period style, but the other hand, they pursued new style of Mongyurok. The characteristics of Mongyuroks in 19th century are the accommodations of the author's daily life and interests. It continued till the early 20th century.

임플란트의 collar design이 변연골과 연조직에 미치는 영향

유현상,강선녀,정창모,윤미정,허중보,전영찬 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

연구 목적: 임플란트 경부가 잘 설계된 경우 양호한 연조직 반응을 통해 변연골을 보존하는데 도움이 된다. 본 실험에서는 연, 경조직 경계부에 가장 가까이 위치하는 임플란트의 collar design이 변연골 변화와 연조직 반응에 미치는 영향을 동물실험을 통해 알아보고자 하였다. 연구 재료 및 방법: 2마리의 건강한 Beagle dog에 임플란트 collar design만 다른 두 종류의 임플란트(Neobiotech Co. Seoul, Korea)를 식립하였다. Collar에 bevel 을 부여한 군(Bevel 군)과 "S"자 형태를 부여한 군(Bioseal 군)으로 나누어 마리 당 7개, 군당 7개, 총 14개의 임플란트를 무작위로 식립한 후 Healing abutment를 즉시 체결하였다. 디지털 표준구내 방사선사진을 이용해 4주 간격으로 총 12주간 근원심 변연골 변화를 관찰하였고, 12주에 희생하여 조직학적 분석을 통해 협설 변연골 흡수 및 임플란트 주변 연조직 반응을 평가하였다. Mann-Whitney test를 통해 동일한 방사선 사진 촬영 시점에서 근원심 변연골 변화량 및 조직계측치를 군 간 비교하였고, Kruskal-Wallis test를 통해 방사선 사진상 근원심 변연골 변화량이 시간에 따른 차이가 있는지 군 내 분석 한 후 Duncan test를 통해 사후 검증하였다(α=.05). 결과: 방사선학적 분석 결과 각 촬영 시점에서 두 군간 근원심 변연골 변화량의 차이를 보이지 않았다(P>.05). 군 내에서 시간에 따른 근원심 변연골의 흡수량을 분석한 결과 Bevel 군에서는 시간에 따른 차이를 보이지 않았으나 (P>.05), Bioseal 군에서는 시간에 따른 차이를 보였으며, 4주및8주와 비교했을 때 12주에서 변연골의 증가를 보였다(P<.05). 조직학적 분석 결과 협설측 변연골 흡수량에서 두 군간 차이를 보이지 않았으나 (P>.05), Bevel 군에 비해 Bioseal 군에서 더 견고한 결합조직부착을 관찰할 수 있었으며, 생물학적 폭경의 값은 두 집단 간 차이를 보이지 않은 반면에 (P>.05), 접합상피부착은 Bevel 군에서 유의하게 길었고, 결합조직부착은 Bioseal 군에서 더 길게 나타났다(P<.05). 결론: Bevel 군에 비해 Bioseal 군에서 결합조직부착은 길게 형성된 반면에 접합상피부착은 더 짧게 나타났으며, 생물학적 폭경과 초기 변연골 흡수에는 차이가 없음을 알 수 있었다. 연조직 반응의 차이가 실제 기능하중 하에서 변연골 변화에 미치는 영향에 대해서 향후 연구가 필요할 것으로 생각된다. PURPOSE. The purpose of this study was to investigate the effects of implant collar design on marginal bone change and soft tissue response by an animal test. MATERIALS AND METHODS. Two types of Implant (Neobiotech Co. Seoul, Korea) that only differs in collar design were planted on two healthy Beagle dogs. The implants were divided into two groups, the first group with a beveled collar (Bevel Group) and the second group with "S" shaped collar (Bioseal group). Standardized intraoral radiographs were used to investigate the mesio-distal change of the marginal bone. Histological analysis was done to evaluate the bucco-lingual marginal bone resorption and the soft tissue response adjacent to the implant. Mann-Whitney test was done to compare the mesio-distal marginal bone change at equivalent time for taking the radiographs and the tissue measurements between the groups. RESULTS. Radiographic and histological analysis showed that there was no difference in marginal bone change between the two groups (P>.05). Histological analysis showed Bioseal group had more rigid connective tissue attachment than the Bevel group. There was no difference in biological width (P>.05). Bevel group showed significantly longer junctional epithelium attachment and Bioseal group showed longer connective tissue attachment (P<.05). CONCLUSION. For three months there were no differences in marginal bone change between the Bevel group and the Bioseal group. As for the soft tissue adjacent to the implant, Bioseal group showed longer connective tissue attachment while showing shorter junctional epithelium attachment. There were no differences in biologic width.

금 합금 보철물의 교합면 삭제로 인한 임플란트-골 계면으로의 열전달에 관한 연구

조재영,강선녀,정창모,윤미정,허중보,전영찬 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

연구 목적: 임플란트-골 계면에서 발생하는 과도한 열은 골유착을 저해하여 임플란트의 실패를 유발한다. 이에 이번 연구에서는 임플란트 금 합금 보철물의 교합면 삭제시 임플란트-골 계면으로의 열전달 양상과 냉각 방식의 효율성을 알아 보고자 하였다. 연구 재료 및 방법: 온도 감지 장치 제작을 위하여 Internal cone 연결형태의 임플란트에 16개의K형 열전대를 부착하여 아크릴릭 레진에 포매하였다. 치과용 금 합금과 주조용 abutment를 사용하여 교합면에 3개의 요철을 가지는 시편을 10개 제작하였고, 연결 나사를 이용하여 임플란트와 연결한 뒤 온도 감지 장치를 37℃로 유지되는 수조에 위치시켰다. 저속 핸드피스와 green stone bur를 이용하여 30초 동안 보철물의 요철을 삭제하였는데, 무냉각군, 공기 냉각 군, 물 분사 냉각 군으로 나누어 요철을 삭제하였다. 보철물이 삭제 되는 동안 임플란트의 부위별로 온도가 0.05초 간격으로 기록되었고, 삭제를 멈춘 뒤에도 무 냉각 군의 경우 임계 온도인 47℃ 이하로 온도가 하강할 때까지, 공기 냉각군과 물 분사 냉각군의 경우 삭제 중단 후 30초 동안 추가로 온도를 기록하였다. 냉각 방식에 따른 임플란트-골 계면의 온도를 알아보고, 임플란트의 부위별 온도변화의 유의차를 알아보기 위하여 one-way ANOVA를 실시하였고, Turkey HSD 이용하여 95% 유의수준에서 사후 검증하였다. 결과: 무 냉각 군은 임플란트-골 계면의 온도가 47℃ 이상으로 상승하였으며, 임플란트의 경부에서 유의하게 높은 열이 측정되었다(P>.05). 공기냉각군과 물분사 냉각군은 임플란트-골 계면의 온도가 47℃ 이하로 유지되었다. 무 냉각 군에서 임플란트 경부의 온도가 47℃에 도달되는 데는 약 10.8 ± 1.5초가 소요되었다. 공기 냉각 군과 물 분사 냉각 군 사이에서는 임플란트-골 계면 온도의 유의차가 없었다(P>.05) 결론: 이상의 결과로부터 임플란트 금 합금 보철물의 교합면 삭제 시, 임플란트 주위 조직에 위해를 가할 수 있는 임계 온도 이상의 열이 발생했음을 알 수 있었으며, 냉각방식은 공기 냉각과 물 분사 냉각 모두 효과적이라고 생각된다. PURPOSE. The purpose of this study was to analyze temperature change along the implant-bone interface induced by grinding the occlusal surface of implant gold prosthesis and to compare the temperature generated by grinding of prosthesis with different cooling methods. MATERIALS AND METHODS. The experimental gold prostheses were fabricated with dental gold alloy and castable abutment. The prostheses had 3 cylindrical protrusions on the occlusal surface with 1mm in height. Temperature was measured using 16 thermocouple wires attached to the implant fixture surface and the fixture was embedded in an acrylic resin block inside the 37℃ water bath. Cylinders were grinded for a period of 30 second with a low-speed handpiece with green stone point. One cylindrical protrusion was grinded without cooling, the second one was grinded with air blow, and the third one was grinded with water-spray. RESULTS. The mean maximum temperature was measured more than 47℃ of the implant and the maximum temperature was measured at the cervical portion of the implant in the group without cooling. There was statistically significant difference between the group without cooling and the groups with cooling (P<.05). However, there was no significant difference at all portion of implant in the groups with cooling (P>.05). CONCLUSION. The results of this study support that the grinding of implant gold prosthesis without cooling may damage the peri-implant tissue. The continuous use of air blow and water-spray adjacent to prosthesis during the grinding of implant gold prosthesis may prove to be beneficial for cooling of the implant.

A Study on the Effectiveness and the Distribution of Isolated Strains by Sputum Collection Methods

Seong, Hee Kyung,Lee, Jeong Nyo 대한의생명과학회 2002 Biomedical Science Letters Vol.8 No.2

This study was performed to investigate the effectiveness of the aspiration trap method for collection of sputum by comparing with the conventional method which was collecting specimens at canular cap swab. In this study, the author tested by two methods to collect specimens from 46 patients who were cared with tracheostomy and intubation at the intensive care unit of an university hospital in Pusan, and investigated the incidence of the lower respiratory tract infection, the consistency between the two methods, the level of specimen contamination. Major results were as follows: Among the patients, 35 were cared with tracheostomy and 11 were cared with intubation. In clinical diagnosis we were classified the subjects in to two group, 17 of pneumonia group and 29 of non-pneumonia group. A total of 247 strains were isolated. Among them, most three strains were Serratia marcescens (62 strains; 25.1%), Pseudomonas aeruginosa (52 strains; 21.1%), and Acinetobacter baumannii (19 strains; 7.8%). Out of total, 188 (76.1%) strains were Gram negative bacilli. The isolated strains by the aspiration trap method were the average 2.1 strains, but by the canular cap swab method were 1.6 strains. In spite of the high contaminated possibility from the incision site and the oral cavity swab, the low isolated rates of the canular cap may be the dried environment of the canular of cap area. But the contamination rates were 57.2% of the canular cap, 51.5% of the oral swab and 50.5% of the incision site swab, respectively. The consistency of predominant microorganisms according to collection method were 86.7% of aspiration, 78.3% of canular, 74.3% of incision, and 63.6% of oral. In conclusion, the aspiration trap method for the sputum collection from the patients with intubation of tracheostomy showed the lower contamination rate of the specimens and it was helpful for rapid, accurated interpretation of the lower respiratory tract infection and hospital infection

Gas Chromatography를 이용한 세균동정법의 임상적 유용성에 관한 연구

함건주,이정녀 인제대학교 1993 仁濟醫學 Vol.14 No.2

본 연구의 목적은 세균동정시 병원성이라고 알려진 세균만을 주로 동정하고 그 이외의 비병원성 혹은 상재균에 속하는 균종들은 무시되어 기회감염의 원인균인지 정확히 알 수가 없었기 때문에 세균세포벽에 존재하는 지방산을 이용한 동정법을 이용하여 흔히 볼 수 없는 세균들을 검출할 수 있는 가능성을 제시하여 임상에 도움을 주는 데 그 목적이 있다. Medically important microorganisms can be identified in many ways. Conventional methods usually rely on the enzyme activity. Immunodiagnostic and nucleotide hybridization techniques have improved sensitivity, specificity, precision, but required probe and high technique. Cellular fatty acid analysis which is one of the chemotaxonomy method is also precise and can result in the definition of high discrimmatory properties. The prospects for using GLC of bacterial cellular fatty acids in diagnostic microbiology have been appreciated for several years in our laboratory. Whole cell fatty acid methylester(FAME) profiles of the bacteria were studied using GLC with application of the fused silica capillary column and the results were as follows : 1.Staphylococcus aureus and coagulase-negative species have qualitatively similar FAME composition, but the quantitative differencies were distinguished from each species. They consist mainly of C14 : 0 iso, C15 : 0 iso, C15 :0 anteiso, C16 : 0, C18 :0, C20 :0. 2.Comparison of FAME of 3 different genera in Enterobacteriaceae which is Proteus milabilis, Klebsiella pneumonia, Citobacter diversus were very different. Typical FAME are C16 : 0, C17 : 0 cyclo, C19 : 0 cyclo, C16 : 1 cis 9, Most also contain C12 : 0 20H, C14 : 0 20H, Cl6 : 1 C in variable amounts. 3.Comparison of FAME of 4 different Family which is Bacillus thuringiensis, Acinetobacter baumannii, Aeromonas caviae, Salmonella choleraesuis were very different and could be distinguished from each other. In conclusion, this study provided clinical feasibility of utilizing GLC in rapid detection and Identification of several bacterial groups or species.

A Study on the Effectiveness and the Distribution of Isolated Strains by Sputum Collection Methods

Seong, Hee-Kyung,Lee, Jeong-Nyo 대한의생명과학회 2002 Journal of biomedical laboratory sciences Vol.8 No.2

This study was performed to investigate the effectiveness of the aspiration trap method for collection of sputum by comparing with the conventional method which was collecting specimens at canular cap swab. In this study, the author tested by two methods to collect specimens from 46 patients who were cared with tracheostomy and intubation at the intensive care unit of an university hospital in Pusan, and investigated the incidence of the lower respiratory tract infection, the consistency between the two methods, the level of specimen contamination. Major results were as follows: Among the patients, 35 were cared with tracheostomy and 11 were cared with intubation. In clinical diagnosis we were classified the subjects in to two group, 17 of pneumonia group and 29 of non-pneumonia group. A total of 247 strains were isolated. Among them, most three strains were Serratia marcescens (62 strains; 25.1%), Pseudomonas aeruginosa (52 strains; 21.1%), and Acinetobacter baumannii (19 strains; 7.8%). Out of total, 188 (76.1%) strains were Gram negative bacilli. The isolated strains by the aspiration trap method were the average 2.1 strains, but by the canular cap swab method were 1.6 strains. In spite of the high contaminated possibility from the incision site and the oral cavity swab, the low isolated rates of the canular cap may be the dried environment of the canular of cap area. But the contamination rates were 57.2% of the canular cap, 51.5% of the oral swab and 50.5% of the incision site swab, respectively. The consistency of predominant microorganisms according to collection method were 86.7% of aspiration, 78.3% of canular, 74.3% of incision, and 63.6% of oral. In conclusion, the aspiration trap method fur the sputum collection from the patients with intubation of tracheostomy showed the lower contamination rate of the specimens and it was helpful for rapid, accurated interpretation of the lower respiratory tract infection and hospital infection.