Retinol 국소도포에 의한 눈가주름 제거효과

전희대,이성열,이혜진,박영립,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

In 3 months randomized, double-blind, vehicle-controlled study of retinol (vitamin A 0.1%-3000IU/g) in the treatment of photoaging skin, especially eye wrinkles. 24 patients applied retinol contained cream to the both eye wrinkles and vehicle cream(placebo) to the same site. Half of the patients received retinol contained cream and half received vehicle cream(placebo). All 24 patients who completed the study showed statistically significant improvement in photoaging eye wrinkles on the retinol contained cream treated group, but not on the vehicle treated group. Eight of the 12 patients who received retinol contained cream to eye wrinkles had improvement in photoaging, whereas only three of the 12 patients who received vehicle cream(placebo) improved. In retinol contained cream group, there is a some relationship between water contents and effects. In other words, as water contents were the higher, effects were the better. The side effects were limited to mild irritation of retinol contained cream treated skin. Retinol contained cream appeared to be safe and effective in the treatment of eye wrinkles.

흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

A Study on Protection of Maternal Antibody against Hantavirus in Rats

우영대,--,--,--,--,-- 대한의생명과학회 2005 Biomedical Science Letters Vol.11 No.1

The etiologic agents of haemorragic fever with ranal syndrom (HFRS) in Korea are Hantaan and Seoul virus in the genus Hantavirus, family Bunyaviridae. In order to elucidate the role of maternal immunity to Hantavirus infection in rats, the protective effect of the maternal antibody were studies by using rats experimentally infected with Seoul virus strain HR80-39. Antibody titers of sera and viral antigen against Seoul virus were investigated by indirect immunofluorscence antibody technique (IFA). The dam sera had IFA antibody titers ranging from 1:128 to 1:1,024 after parturition. In fetuses, IFA antibody titers ranged from 1:16 to 1:64 just after birth, increased to peak titers ranged from 1:256 to 1:1,024 in the 2nd week after birth. Challenged newborn rats had IFA antibody titers ranging from 1:64 to 1:1,024 after inoculation. No viral antigen was detected in lungs or other organs of the newborn rats. The maternal antibody to Seoul virus was transferred prenatally through placenta and postnatally via colostrum from immune dams to their offspring. These results demonstrated that maternal antibody to Seoul virus was quite effective in protecting newborn rats against same virus infection.

악성림프종 환자에서 복합화학요법으로 유발된 백혈구 감소증에 대한 인형 재조합 과립구 집락형성-촉진인자(rhG-CSF: Neutrogin)의 효과

박성규,전진우,기신영,유병우,김홍수,백승호,원종호,홍대식,박희숙 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Clinical effects of rhG-CSF were investigated in 17 patients receiving chemotherapy for non-Hodgkin's lymphoma. Patients were given G-CSF 2㎍/㎏/day after 2nd cycle chemotherapy for least 14 consecutive days, and clinical and laboratory results were compared to results of the first cycle. Treatment with G-CSF resulted in increase of mean WBC count(952.9±152.2㎜³vs 1882.4±350.4/㎜³) and neutrophil count(212.9±53.0/㎜³vs 841.5±238.0/㎜³), reduced the duration of leukocytopenic days(12.4±1.3 days vs 5.5±1.0 days, WBC count less than 4000/㎜³) and neutropenic days(4.5±0.9 days vs 2.3±0.7 days, neutrophil count less than 500/㎜³), and reduced the duration of neutropenic fever(5.8±1.1 days vs 0.9±0.5 days). The side effects of G-CSF were not so significant. These results demonstrated that G-CSF is safe and useful for the treatment of neutropenia induced by anticancer chemotherapy of non-Hodgkin's lymphoma and reducing the incidence of febrile periods and duration of antibiotic administration.

다공질규소 microcavity의 페브리-페로 필터 특성

이춘우,박대규,홍사용,김영유,전종현 公州大學校 基礎科學硏究所 1999 自然科學硏究 Vol.8 No.-

p형 단결정규소 웨이퍼를 15% HF-에탄올 용액에서 양극 산화시켜 다공질규소를 얻는 과정에서 전류밀도에 따라 굴절률이 변하는 다층의 다공질규소층(porous silicon multilayer)을 구현하였다. 그리고 다층의 다공질규소층(I), 다공질규소 발광층, 또 다른 다층의 다공질규소층(II)의 순으로 구성된 porous silicon microcavity(PSM)를 제작하고 그 물성을 조사하였다. PSM 상하에 위치한 다층의 다공질규소층의 단면을 AFM(Atomic Force Microscope)으로 조사한 결과 고굴절률과 저굴절률이 주기적으로 교차하는 층이 균일하게 형성되었으며, 중앙의 다공질규소 발광층도 균일하게 나타났다. 다층의 다공질규소층 및 다공질규소 발광층의 두께를 각각 실효파장의 1/4배 및 2배가 되도록 하였을 때 특정파장의 필터로 쓰일 수 있는 페브리-페로 간섭 필터(Fabry-Perot interference filter)의 특성이 나타났다. 또한 PSM의 발광 스펙트럼은 그 반치폭이 현저히 감소하고 발광의 세기가 크게 증가되는 경향을 보였다. 또한 발광파장을 600 nm로 조절하여 PSM을 구현하고 발광 특성을 관찰한 결과 600 nm 부근에서도 같은 현상이 일어나 발광의 최대 봉우리 파장값을 이동시킬 수 있는 필터로서의 역할이 가능함을 보였다. In the process of obtaining porous silicon by anodizing p-type doped crystalline silicon wafer in 15 % HF-ethanol solution, we obtained porous silicon multilayers which had periodically varying refractive index by the current density. We fabricated the porous silicon microcavity(PSM) which consist of porous silicon multilayers(I), active layer of porous silicon and porous silicon multilayers(II) and investigated its physical properties. The AFM(Atomic Force Microscope) measurement from the cross section of multilayers I and II) shows uniformity of high refractive index and low index layers as well as the active layer. We observed the characteristics of Fabry-Perot interference filter when the thickness of layers was 1/4 and the thickness of active layer was twice of the effective wavelength, which can be used as a filter for specific wavelength. We found the emission characteristic from the PSM, which FWHM(Full Width Half Maximum) was considerably decreased and emission intensity was increased. And as a result of fabricating PSM which consisted of 600 nm in the light emission wavelength and observing the light emission properties, We found out that there was the same phenomenon in 600 nm wavelength and PSM could act as a filter which could shift the maximum of the emitted light.

세포질내 정자주입법(ICSI)에 있어서 정자흡입 및 난자내 주입방법에 관한 연구

이택후,김항진,송건호,김대근,전상식,박윤규,서태광,전병균,류은경,이은숙,문진수,김광철 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1

Study on Method of Sperm Aspiration and Injection into an Oocyte in Intracytoplasmic Sperm Injection(ICSI) Immobilization of spermatozoa prior to intracytoplasmic sperm iniection(ICSI) sometimes results in crooked tail and this makes it difficult to aspirate sperm into an injection pipette tail first. Head-first sperm aspiration into an injection pipette avoid this problem due to the bigger size of the sperm head. The effect of head or tail-first sperm injection into an oocyte on fertilization cleavage, percentage of grade I embryos and development to blastocyst stage in ICSI program has been studied. A single living immobilized spermatozoa from oligoasthenozoospermic patient was injected into an oocyte head-first or tail-first according to the treatment. Eighteen hours after microinjection, oocytes ware inspected for survival and fertilization Fertilized oocytes with two pronuclei were cultured in 30μl drop of mHTF supplemented with 10% heat-inactivated follicular fluid(FF) at 37℃. On day 2. embryo transfer was performed with cleaved embryos. The remaining 2-8 cell stage embryos were co-cultured with BRL cells in mHTF + 10% FF for 72 hours and the developmental stage was observed. The data were analyzed by Analysis of Variance. A total of 164 oocytes from 36 cycles were assigned to earth treatment and ICSI was performed(88 head-first, tail-first). The rates of normal fertilization were 81.8% and 76.3% for head-first and tail-first, respectively. Of the fertilized oocytes, the percentage of cleaved embryos and the percentage of grade 1 embryo among cleaved embryos were 88.9% and 68.8%, 93.1% and 74.1% for head-first and tail-first, respectively. Of the 2-8 cell embryos cultured, 44.4%(16/36) and 50.0%(10/20) for head first and tail first, respectively developed to blastocyst stage. There were no differences in fertilization, cleavage, rates of grade 1 embryos, and development to blastocyst stage. In conclusion, head-first or tail-first sperm injection into an oocyte in ICSI program does not affect fertilization and subsequent embryo development to blastocyst stage in vitro.

해외법창(海外法窓) : 중국의 법관연수제도

전대규 ( Dae Kyu Jeon ) 법조협회 2009 법조 Vol.58 No.4

중국에서 법관이 연수를 받는 것은 권리이자 의무이다. 중국은 법관연수와 관련하여《법관법》을 비롯해서 <법관연수조례> 등 법률적 근거를 마련하고 있을 정도로 법관연수를 중요시 하고 있다. 중국의 법관연수는 예비법관연수와 재직법관연수가 있다. 예비법관연수는 임용이 예정된 법관을 대상으로 하는 연수이다. 재직법관연수는 현재 재직하고 있는 법관을 대상으로 하는 연수로 보직연수, 승진연수와 직무연수가 있다. 보직연수는 지방 각급 인민법원의 원장 또는 부원장으로 승진 또는 전근하기 전에 실시하는 연수이다. 승진연수는 1급법관이 고급법관으로 승진하기 전에 반드시 받아야 하는 연수이다. 직무연수는 현재 직위의 전문지식을 새롭게 하고 심판업무기능을 향상시키기 위하여 실시하는 연수이다. 중국의 법관연수는 원칙적으로 국가법관학원과 성급 법관연수기관이 담당하고 있다. 그러나 일부 지역에서는 필요에 따라 고급인민법원의 허가를 받아 제3급의 연수기관을 두어 연수를 담당하도록 하고 있다. 중국법관연수는 기본적으로 업무를 떠나 대면교육 형식으로 하고 있으나, 현재는 비용문제나 연수기관의 연수능력문제 등으로 인터넷을 통한 교육을 새롭게 개발하고 있다. 그리고 기본적으로 법관연수의 교수는 법관이 법관을 교육한다는 원칙에 따라 현직에 있는 법관 중에서 선발하고 있다. 중국은 법관연수에 대해 많은 연구를 하여 그 개혁의 기본방향을 제시하고 있다. 예비법관연수제도의 개혁, 규범화된 인터넷 연수체계의 확립, 고급인재와 서부지역 법관연수의 강화, 새로운 연수체계(승진 시 연수)의 실시, 연수관리의 강화와 연수권위의 확립, 교수개혁을 중심으로 교육연수기관건설을 강화하는 것이 그것이다.

순환골재 미분말 치환방법이 고유동 모르터의 유동특성에 미치는 영향

전규남(Jeon, Kyu Nam),최현규(Choi, Hyun Kyu),손호정(Son, Ho Jung),백대현(Baek, Dae Hyun),한민철(Han, Min Cheol),한천구(Han, Cheon Goo) 한국콘크리트학회 2010 한국콘크리트학회 학술대회 논문집 Vol.2010 No.11

중국법상 섭외사건의 국제재판관할에 관하여

전대규(Jeon Dae Kyu) 한국국제사법학회 2012 國際私法硏究 Vol.- No.18

중국에서 섭외민사소송이란 인민법원이 쌍방당사자와 기타 소송참여인의 참여하에 섭외민사사건을 심리하고 해결하는 활동을 말한다. 중국 섭외 민사소송절차의 국내법상의 법원으로 《민사소송법》 제4편 및 최고인민법원이 섭외민사소송절차와 관련하여 제정한 사법해석이 있다. 한편 《민사소송법》 제5조 및 제4편 제24장은 중국민사소송법을 적용한다는 원칙 등과 같은 섭외민사송절차에 관한 일반원칙을 규정하고 있다. 섭외민사소송관할(국제재판관할)이란 한 나라의 법원이 섭외적 요소를 가지고 있는 민사사건에 대하여 향유하는 재판권을 말한다. 중국 《민사소송법》에는 섭외민사소송관할에 관한 일반적인 규정은 없다. 《민사소송법》 제4편 제24장은 섭외민사소송사건의 관할에 대하여 규정하고 있으나 제24장이 규정하는 섭외민사소송사건관할은 계약과 기타 재산권분쟁사건에만 적용된다. 따라서 계약과 재산권분쟁 이외의 섭외민사사건은 《민사소송법》 제1편 제2장의 규정에 따라 처리한다. 중국 《민사소송법》은 피고가 중국에 주소지를 가지고 있는 경우 피고주소지를 보통지역관할권의 근거로 삼고 있고, 중국에 주소를 두고 있는 않는 경우 계약체결지 등 실제적인 관련이 있는 인민법원에 관할권을 인정하고 있다. 이외 소송경합, 합의관할, 전속관할, 집중관할에 관하여도 규정하고 있다. 사법실무상으로는 국제재판관할이 충돌할 경우 부적절한 법정지의 원칙을 적용한 사례도 발견된다. International civil litigation in China is that international civil cases are tried and solved by Chinese people’s court with the participation of both parties and orther litigation parties. The sources of chinese law regarding international civil litigation are Part 4 of 〈Law of Civil Procedure of the People’s Republic of China〉 and the judicial interpretation that Chinese Supreme people’s court enacted regarding international civil litigation. The jurisdiction of international civil litigation is the authority of one nation’s court to apply laws to cases involving ‘foreign elements’. There’s no general provision regarding jurisdiction of international civil litigation in 〈Law of Civil Procedure of the People’s Republic of China. Part 4, Chapter 24 of 〈Law of Civil Procedure of the People’s Republic of China〉 regulates only contracts and other property dispute cases. The other cases involving foreign elements are regulated by Part 1, Chapter 2 of 〈Law of Civil Procedure of the People’s Republic of China〉. A civil lawsuit initiated against a citizen shall be under the jurisdiction of the people’s court in the place where the defendant has his or her domicile(or habitual residence) and a lawsuit brought against a defendant who has no domicile in the People’s republic of China may be under the jurisdiction of the people’s court in the place where the contract is signed or performed or where the subject matter of the action is located. And 〈Law of Civil Procedure of the People’s Republic of China〉 also stipulates multiple claims, referral and designation of jurisdiction, exclusive jurisdiction, concentration of jurisdiction. It is also founded that the “Forum non Conveniens” applied to the cases when multiple courts has the jurisdiction of international civil litigation.

자기 차폐방식을 적용한 자동차용 비접촉식 토크센서에 관한 연구

전창남(Chang-Nam Jeon),한창규(Chang-Kyu Han),양현일(Hyun-il Yang),전민석(Min-Seok Jeon),이석우(Seag-Woo Lee),조남규(Nam-Kyu Cho),이대성(Dae-Sung Lee) 한국자동차공학회 2009 한국자동차공학회 부문종합 학술대회 Vol.2009 No.4

The present paper relates to a study on automotive non-contacted torque sensor for MDPS or EPS, which includes Hall IC, circular permanent magnet and apparatus of magnetic shield using soft ferromagnetic material and is mounted to torsion bar connected steering column ? shaft assembly. Torque sensor can be promptly and precisely measured by change of magnetic field to loaded twist torque when a driver operates steering wheel and can be obtained better durability then contacted type such as using strain gauge or potentiometer.