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RISS 인기검색어
- 검색키워드
- 저자 : Jeelani, Samoon (검색결과 4 건)
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Migration in propinquity with development: a spatial analysis of Kashmir Valley, India
Peer Jeelani,Farzana Ahad,Shamim Ahmad Shah,Huma Rashid,Nazia Bano 대한공간정보학회 2023 Spatial Information Research Vol.31 No.4
Migration is the primary demographic process that shapes where people live and plays an essential role in how humans have changed over time. People migrate for various reasons, but the predicted economic disparity between industrialized and developing regions is a powerful motivator for people to relocate. As a result, migration has an impact on development, and development also affects migration. Because of the vast differences in development among India's regions, the future of population dynamics will rely more on migration than fertility and mortality processes. The present paper analyzes the spatial patterns of internal migration, variations in the level of development, and the propinquity between the two. Secondary data were used from the census of India, government reports, and research publications. Data were analysed using Karl Pearson's correlation coefficient and a t-test to test the observed correlation's significance. The results revealed a high positive correlation between internal migration and levels of development (r = 0.791). Out of thirty-three development variables, only sixteen have a higher significant relationship with internal migration, which mainly determines population characteristics, education facilities, employment opportunities, and infrastructural facilities.
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Preliminary studies on the microplastic pollution in Dal lake, Kashmir (first report)
Firdous, Juhi,Mathur, Yatindra Kumar,Jeelani, Mubashir,Aziz, Adnan,Azmat, Seema,Mudasir, Syeed Techno-Press 2020 Advances in environmental research Vol.9 No.4
We provide the first study on the occurrence of microplastics in Dal lake, Kashmir, India. Microplastics act as catastrophe that trigger many environmental problems. The key origins of microplastics are larger plastics, which split into smaller plastics after UV light disintegration. There is relatively little work carried out on the existence of microplastics. The present work has been undertaken on the occurrence of microplastics at four pre-selected sites (surface water) in Dal lake, Kashmir. The samples were taken to the laboratory to dissolve organic matter by using H2O2 (6%). To speed up the organic digestion; the treated mixture was heated on a hot plate at 70℃. The mixture was then subjected to density separation. The supernatant obtained was observed under the microscope (10X) and measurements were taken. At site-I, the microplastics ranged from 2-3 mm, site-II 5-6 mm, site-III 3-4 mm, site-IV 4-5 mm in thickness, indicating the presence of microplastics in the lake. The presence of microplastics indicated that the lake has undergone an anthropogenic change over a period of time. Our research highlights the value of enhancing the quality of the drainage system and sewage disposal. This work can be helpful to recognize successful microplastic control management techniques and possible threats associated with the Dal lake. So far, no such data on the presence of microplastics in Kashmir lakes is available.
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Adeeba Khadim,Bibi Zareena,Saddam Hussain,Syed Usama Yaseen Jeelani,Arslan Ali,Syed Ghulam Musharraf 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.107 No.-
High-throughput and efficient identification of drugs in a complex mixture is required in many pharmaceuticalindustries and drug testing laboratories. The present study aims to utilize an efficient poolingstrategy for the preparation of high-resolution tandem mass spectrometry (HR-MS/MS) library of drugswith different therapeutic properties. Compounds were classified into four classes of low, medium–low,medium–high and high log P values and were pooled into five pools (100 drugs pool). Compounds withisobaric and close log p values were placed in separate groups to overcome the co-elution problem. Liquidchromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) was utilized to generate ahigh-resolution tandem mass spectrometry (MS/MS) spectral library in both positive and negative electrosprayionization modes of 491 drugs. Spectra were collected by LC-MS/MS analysis using system automatedcollision energy i.e. of 25–60 eV and four predetermined collision energies (10, 20, 30 and 40 eV)for each compound using schedule precursor list of [M + H]+ and [M + Na]+ ions. To validate the applicabilityof the library, serum samples spiked at three concentrations close to bioavailability (0.308 ng/mL,3.08 ng/mL and 30.08 ng/mL) of drugs and were analyzed by LC-QTOF-MS/MS. The HRMS library searchsuccessfully identified all compounds present in the spiked serum samples based on exact masses of precursorions, MS/MS data, and retention time etc. The accurate mass LC-QTOF-MS based tandem massspectral libraries represent a useful tool for the identification of drugs in clinical samples, for pharmacologicaland forensic screening applications etc.
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Bhat, Gulzar,Bhat, Ashaqullah,Wani, Aadil,Sadiq, Nida,Jeelani, Samoon,Kaur, Rajinder,Masood, Akbar,Ganai, Bashir Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Cancer is a complex disease and the genetic susceptibility to it could be an outcome of the inherited difference in the capacity of xenobiotic metabolizing enzymes. Glutathione-S-transferases (GSTs) are phase II metabolizing enzymes whose various genotypes have been associated with increased risk of different types of cancer. Null mutations caused by the deletion of the entire gene result in the absence of the enzymatic activity and increase in the risk of developing cancer including chronic myeloid leukaemia (CML). In the present case-control study we evaluated the effect of null mutations in GSTM1 and GSTT1 genes on the risk of developing CML. The study included 75 CML patients (43 males and 32 females; age (mean ${\pm}$ S.D) $42.3{\pm}13.4$ years) and unrelated non-malignant controls (76 male and 48 females; age (mean ${\pm}$ S.D) $41.5{\pm}12.9$). The distribution of GSTM1 and GSTT1 genotypes in CML patients and controls was assessed by multiplex-PCR method. Logistic regression was used to assess the relationship between GSTM1 and GSTT1 genotypes and risk of CML. Chi-square test was used to evaluate the trend in modulating the risk to CML by one or more potential high risk genotype. Although GSTM1 null genotype frequency was higher in CML patients (41%) than in the controls (35%), it did not reached a statistical significance (OD = 1.32, 95% CI: 0.73-2.40; P value = 0.4295). The frequency of GSTT1 null genotypes was higher in the CML patients (36%) than in the controls (21%) and the difference was found to be statistically significant (OD = 2.12, 95% CI: 1.12-4.02; P value = 0.0308). This suggests that the presence of GSTT1genotype may have protective role against the CML. We found a statistically significant (OD = 3.09, 95% CI: 1.122-8.528; P value = 0.0472) interaction between the GSTM1 and GSTT1 null genotypes and thus individuals carrying null genotypes of both GSTM1 and GSTT1 genes are at elevated risk of CML.
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