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      • KCI등재후보

        Protective Effects of N-acetylcystenine and Selenium against Doxorubicin Toxicity in Rats

        Yeo-sung Yoon,Sun-don Kim,Min-hye Lee,Heung-shik S.Lee,In-se Lee,Je-kyung Sung,Eun-sung Park 대한수의학회 2003 JOURNAL OF VETERINARY SCIENCE Vol.4 No.2

        Effects of N-acetylcysteine and Selenium against Doxorubicin Toxicity in RatsEun-sung Park, Sun-don Kim1, Min-hye Lee, Heung-shik S. Lee, In-se Lee, Je-kyung Sung and Yeo-sung Yoon*

      • SCOPUSSCIEKCI등재

        한국인 젊은 여성의 심미적인 안면 연조직 형태에 관한 두부 X-선 계측학적 연구

        우제경,성재현,권오원 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.2

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 7시까지 원문보기가 가능합니다.

        본 연구에서는 대구에서 활동하고 있는 모델과 심미적인 안모를 가졌다고 추천받은 68명의 젊은 여성을 대상으로 하여 두부X-선 사진, 정모 사진과 측모 실루엣 사진을 채득하였다. 두부X-선 사진의 연조직 측모선만을 사용한 3명씩의 측모 실루엣을 FH plane이 평행하게 한 장에 그려서 제작한 사진을 경북대학교 미술학과 재학생 7명과 교정 전공의 15명에게 평가하게 하였으며 정모 사진을 교정 전공의만 평가하게 하였다. 아주 좋은 경우를 9점, 좋은 경우를 7점 보통인 경우를 5점, 좋지 않은 경우를 3점으로 처리토록 하였다. 측모 실루엣에서 교정 전공의와 미대생의 심미안간의 상관관계, 교정 전공의가 평가한 정모와 측모의 심미성간의 상관관계, 교정 전공의가 평가한 측모 실루엣의 평균 점수가 5점 이상인 38명의 측모 계측항목과 측모 심미성간의 상관관계를 분석하여 다음과 같은 결론을 얻었다. 1. 측모 실루엣에서 교정 전공의와 미대생의 심미안간의 상관관계는 유의성있게 나타났다(r=0.67, P=0.0001). 2. 교정 전공의가 평가한 정모와 측모의 심미성간의 상관관계는 유의성있게 나타났다(r=0.26, P=0.0381). 3. 측모 실루엣과 상관관계가 유의성있게 나타난 항목은 Na-Pog to N′, BNV to Pog′, BNV/B′-Pog′, Ls-Li-Pog′, Li-B′-Pog′, Z angle이었다.(P<0.05). 4. 측모 계측항목의 평균치 및 표준편차를 구하였다. Cephalometric radiographs, frontal photographs and profile silhiuette phogographs of 68 young adult female who were model or were recommended to have esthetic face were used in this study. 7 Students in department of Art of Kyungpook national university and 15 orthodontists estimated profile slides which were made of 3 profile silhouettes in parallel with FH plane. Profile silhouettes were made of soft tissue profile line of cephalometric radiograph. Only orthodontists estimated frontal photographs. Students and Orthodontists score 9 in excellent case, score 7 in good case, score 5 in average case, score 3 in poor case. Correlation analysis between orthodontists` esthetic concept and Artists` esthetic concept, between frontal view esthetics and profile view esthetics which estimated by orthotontists. between profile view esthetics and profile measurements which consisted of measurements of 38 female who were scored above 5 mean score in profile silhouette by orthodontists were done. And the finding in this study indicated the following 1. Correlation between orthodontists` esthetic concept and Artists` esthetic concept in profile silhouette was significant(r=0.67, P=0.0001). 2. Correlation between frontal view esthetics and profile view esthetics which estimated by orthodontist was significant(r=0.26, P=0.0381). 3. Measurements which had significant correlation between profile measurements and profile view esthetics were Na-Pog to N′, BNV to Pog′, BNV/B′-Pog′, Ls-Li-Pog′, Li-B′-Pog′and Z angle(P<0.05). 4. Mean and standard deviation of profile measurements of 38 female were obtained.

      • KCI등재후보

        전산유체 기법을 이용한 DAF 부상조에서의 수리 특성 고찰

        김성훈,유제선,김영미,박희경 대한상하수도학회 2002 상하수도학회지 Vol.16 No.4

        Dissolved air flotation is a solid-liquid separation process that uses fine rising bubbles to remove particles in water. DAF is found most effective in treating algae and lower density flocs that are hard to remove in sedimentation process. Some researcher reports the results of an experimental study which examined the flow within the flotation zone of a DAF tank (ONeill at al., 1997). I would be concluded that, in general, the flow within flotation zone is robust and that differences in the performance of individual DAF tanks must be the result of processes occurring within the contact zones of these tank, not as the result of flotation processes. In this research, the authors thought that the efficiency of the DAF process is strongly related to bubble size. It means bubble rising velocity at the air injection nozzle is most important factor of DAF process. However, bubble movement in DAF tank is somewhat complicate, so it is hard to make up conceptual model through simple mass balance as other researchers did (Leppinen at. al., 2000). For the modeling of turbulent 2-phase flow in the tank, the standard k-ε model was used in CFD code because it is widely accepted and the coefficients for the model are well established. This model uses the eddy-viscosity hypothesis for the turbulence. As the result of this study, the authors concluded that bubble size and its rising velocity is very important factor of DAF process and the recycle ratio must be also consider for the flotation zone parameter. Also, For the improved model, relation between turbulent intensity and bubble-particle attachment must be studied.

      • 燻炭栽培時의 給液時間이 오이와 토마토의 生育과 收量에 미치는 영향

        林相喆,金炅濟 동국대학교 대학원 1989 大學院硏究論集-東國大學校 大學院 Vol.19 No.-

        This study was conducted to investigate the effect of supplying interval of solution on the growth of cucumber and Tomato in nutri-culture. The major results obtaince were as follows. 1. Cucumber 1) Plant growth in early stage, as well as total yield, was the best in 30∼30 treatment. 2) First harvesting date was 7 and 12 days earlier in 30∼30 treatment than in 30∼90, 30∼150 treatment. 3) It can be recommended that the optimum supplying time of solution in cucumber should be 30∼30 until middle stage to promote the growth and then 30∼90. 2. Tomato 1) As the supplying time increased, over growth was obseued but retarded growth was found in 30∼150 treatment. 2) The plant height and stem diameter were good 30∼90 treatment and total yield of that treatment was similar to 30∼30 treatment. 3) Suitable supplying interval of solution in tomato was 30∼90 from early to late stages constantly.

      • 우심방과 우심실의 거대 심장 혈관종 1예

        김제열,조상호,김건일,허경림,김현숙,조구영,최영진,이원용,임종윤 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Cardiac tumors, especially the primary tumors involving any part of the heart are extremely rare and its relative incidence has been reported to be approximately 0.02%. We report a patient with huge cardiac hemangioma who complained of shortness of breath, general weakness, and dizziness, Imaging study by echocardiography and computed tomography of thorax revealed a huge lobulating mass like a bunch of grapes in the right chamber of heart. The surgical exploration of thorax was performed and a histological diagnosis of spindle cell hemangioma was obtained by microscopy. The patient was treated by surgical resection of the tumor and doing well after surgery. Our experience indicated that prompt diagnosis and treatment of cardiac hemangioma is imperative for patients' prognosis.

      • Methicillin내성 포도 구균의 기타 항균제에 대한 감수성

        이경수,이제철,설성용 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.1

        A total of 204 strains of Staphylococcus aueus isolates in 1987, 1988, and 1989 were studied for the frequency of methicillin-resistant S. aureus (MRSA) and antimicrobial susceptibility and also were examined for oxacillin screening tst and change of minimal inhibitory concentration (MIC) of methicillin at the various conditions. When S. aureus were incubated on the agar media supplemented with 4% NaCl at 35℃ for 72 hours, 33(16.2%) of 204 strains were resistant to methicillin. In oxacillin screening test, oxacillin resistance was found in 33 (16.2%) of the 204 strains. Compared to the MIC of methicillin, oxacillin screenigng positive strains were not same strains of methicillin resistant S. aureus. Total frequency of MRSA was 24 (11.8%) of 204 strains. The frequencies of MRSA in 1987, 1988, and 1989 were 12 strains (9%), 11 strains (16.9%), and 1 strain(20%), respectively and MRSA increased yearly. All MRSA had multiple antibiotic resistance from 9 to 15 tested antibiotics and resistance to 12 antibiotics was the most predominant. All MRSA were resistant to kanamycin, gentamicin, penicillin and cefoxitin. More than 75% MRSA were resistant to amikacin, cefotaxime, cephalothin, tetracycline, rifampin and erythromycin. All MRSA were susceptible to minocycline, vancomycin and trimethoprim-sulfamethoxazole. More than 75% MRSA strains were susceptible to norfloxacin, ciprofloxacin and doxycycline.

      • KCI등재

        전산유체 기법을 이용한 용존공기부상법에서의 접촉도 조건변화에 따른 충돌효율평가

        김성훈,유제선,박희경 대한상하수도학회 2004 상하수도학회지 Vol.18 No.2

        Dissolved air flotation (DAF) is a solid-liquid separation process that uses fine rising bubbles to remove particles in water. Most of particle-bubble collision occurs in the DAF contact zone. This initial contact considered by the researchers to play a important role for DAF performance. It is hard to make up conceptual model through simple mass balance for estimating collision efficiency in the contact zone because coupled behavior of the solid-liquid-gas phase in DAF system is 90 complicate. In this study, 2-phase(gas-liquid) flow equations for the conservation of mass, momentum and turbulence quantities were solved using an Eulerian-Eulerian approach based on the assumption that very small particle is applied in the DAF system. For the modeling of turbulent 2-phase flow in the reactor, the standard k-ε mode Ⅰ(liquid phase) and zero-equation(gas phase) were used in CFD code because it is widely accepted and the coefficients for the model are well established. Particle-bubble collision efficiency was calculated using predicted turbulent energy dissipation rate and gas volume fraction. As the result of this study, the authors concluded that bubble size and recycle ratio play important role for flow pattern change in the reactor. Predicted collision efficiency using CFD showed good agreement with measured removal efficiency in the contact zone. Also, simulation results indicated that collision efficiency at 15% recycle ratio is higher than that of 10% and showed increasing tendency of the collision efficiency according to the decrease of the bubble size.

      • KCI등재

        레니텍^(�) 정(말레인산 에날라프릴, 10mg)에 대한 에나레이스 정의 생물학적 동등성

        조성희,하용화,홍성제,서성훈,류재환,김동현,이경태 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.3

        The purpose of present study was to evaluate the bioequivalence of two enalapril maleate tablets, Renitec^(™) (MSD Korea Ltd.) and Enalace ^(™) (Welfide Korea Ltd.), according to the guidelines of Korea Food Drug Administration (KFDA). Twenty-four normal male volunteers, 22.33±2.55 year in age and 66.54±8.30 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containint 10 ㎎ of enal-april maleate per tablet wre orally administered, blood was taken at predetermined time intervals and concentrations of enalapril in plasma were determined using LC-MS-MS. Pharmacokinetic parameters such as AUC_(t), C_(max) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t) and C_(max) untransformed T_(max). There were no sequence effects between two formulations in these parameters. The 90% confidence intervals for the log transfored data were acceptance range of log0.8 to log1.25(e.g., log1.02∼log1.14 and log1.03∼log1.19 for AUC_(t) and C_(max), respectively). The major parameters, AUC_(t) and C_(max), met the criteria of KDFA for bioequivalence indicating that Enalace^(™) tablet is bioequivalent to Renitec^(™) tablet.

      • KCI등재

        Dissolved Air Flotation(DAF) 접촉조의 수리동력학적 조건이 입자의 제거에 미치는 영향

        유제선,김성훈,신은허,박희경 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

        Hydrodynamic conditions for optimum solids capture within the contact zone, which are governed by the geometry and flow, are not yet well understood. In this research, dimensionless parameters which represent hydrodynamic conditions in the contact zone were derived, using the Buckingham π theorem. Those parameters are Reynolds No. (Re), Froude No. (Fr), Weber No. (We), Local Weber No., and Bubble Capacity No. (Bc). The particle removal rate was investigated by changing each value of the dimensionless parameters. The experimental results indicate that particle removal rate, when gravity dominates and the flow is semi-turbulent (Fr < 0.3, Re < 8000), is higher than when inertia dominates and flow is turbulent. For the We, higher removal rates were obtained in the range of the We < 40. Relative to the Local We, smaller bubbles which are influenced more by surface tension than inertia, demonstrated a higher particle removal rate than larger bubbles. For the Bc, the optimal range is from 0.3 to 0.5. We suggest that these dimensionless parameters can be used to diagnose the performance of and to design a DAF reactor.

      • 養液栽培 管理方法에 關한 硏究

        金炅濟,林相喆 東國大學校 1989 論文集 Vol.28 No.-

        This study was conducted in 1984 and 1985 to utilize the simplified cultural equipments and find the simplified cultural methods in nutrient solution culture. Results obtained were as follows : 1. material cost of equipment it lowest priced in water culture and highest priced in rice-charcoal culture made of stylofoam. 2. ratio of culture bed to total cost ranges from 37.2% to 51.3%. 3. although circulating system was more effective than air comp, the air comp is usuable in case of small simplified cultural practice. 4. incase of spray culture, highly concentration of solution were promotive to rapid growth and more yield in cucumber and tomato.

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