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Distributed Fair Scheduling for Wireless Mesh Networks Using IEEE 802.11
Janghwan Lee,Hyunsoo Yoon,Ikjun Yeom IEEE 2010 IEEE Transactions on Vehicular Technology VT Vol.59 No.9
<P>In IEEE-802.11-based wireless mesh networks (WMNs), unfair bandwidth sharing may arise, because the carrier sense multiple access with collision avoidance protocol is designed to provide per-station fairness only in one hop. As the hop count from a mobile client to the gateway node increases, the throughput of the node drastically decreases. In this paper, we propose a fair bandwidth allocation scheme for multiradio multichannel WMNs. This scheme provides fair bandwidth sharing among the nodes in a WMN, regardless of their hop distance from the gateway node. To achieve fairness, we first estimate the number of active nodes attached to each router and calculate the effective weights of routers based on the estimation. Then, we differentiate their contention window using their weights. For this method, we derive a multihop packet collision model. The proposed scheme is fully distributed and does not require any global information. Through an extensive simulation study, we show that our scheme ensures per-node fairness without loss of the total aggregate throughput.</P>
Lee, Jaemin,Kang, Tae Heung,Yoo, Wonbeak,Choi, Hyunji,Jo, Seongyea,Kong, Kyungsu,Lee, Sang-Rae,Kim, Sun-Uk,Kim, Ji-Su,Cho, Duck,Kim, Janghwan,Kim, Jeong-Yoon,Kwon, Eun-Soo,Kim, Seokho AMERICAN ASSOCIATION FOR CANCER RESEARCH 2019 CANCER IMMUNOLOGY RESEARCH Vol.7 No.2
<P>The homing of natural killer (NK) cells is often inhibited by pancreatic cancer tumors. A mesothelin-directed antibody conjugated to a cleavable NK cell—recruiting chemokine increased NK-cell infiltration of PDAC tumors, reduced tumor burden, and improved survival.</P><P>Natural killer (NK) cells are primary immune cells that target cancer cells and can be used as a therapeutic agent against pancreatic cancer. Despite the usefulness of NK cells, NK-cell therapy is limited by tumor cell inhibition of NK-cell homing to tumor sites, thereby preventing a sustained antitumor immune response. One approach to successful cancer immunotherapy is to increase trafficking of NK cells to tumor tissues. Here, we developed an antibody-based NK-cell–homing protein, named NK-cell–recruiting protein-conjugated antibody (NRP-body). The effect of NRP-body on infiltration of NK cells into primary and metastatic pancreatic cancer was evaluated <I>in vitro</I> and in murine pancreatic ductal adenocarcinoma models. The NRP-body increased NK-cell infiltration of tumors along a CXCL16 gradient (CXCL16 is cleaved from the NRP-body by furin expressed on the surface of pancreatic cancer cells). CXCL16 induced NK-cell infiltration by activating RhoA via the ERK signaling cascade. Administration of the NRP-body to pancreatic cancer model mice increased tumor tissue infiltration of transferred NK cells and reduced the tumor burden compared with that in controls. Overall survival of NRP-body–treated mice (even the metastasis models) was higher than that of mice receiving NK cells alone. In conclusion, increasing NK-cell infiltration into tumor tissues improved response to this cancer immunotherapy. The combination of an NRP-body with NK-cell therapy might be useful for treating pancreatic cancer.</P>
Plasma-Treated Flexible Aminoclay-Decorated Electrospun Nanofibers for Neural Stem Cell Self-Renewal
Lee, Young-Chul,Lee, Hyun Uk,Lee, Minhyung,Kim, Janghwan,Huh, Yun Suk American Scientific Publishers 2016 Journal of nanoscience and nanotechnology Vol.16 No.2
<P>Biocompatible Mg- and Fe-aminoclays (MgAC and FeAC)-decorated polyacrylonitrile (PAN) nanofibers (NFs, diameter range: 190-380 nm) are prepared by the electrospinning process. There is a large increase in the biomolecular activities of the PAN NFs that were oxygen plasma (OP)-treated (the OPNFs) relative to those of the pristine PAN NFs, due to the OP treatment's carboxylation and/or hydroxylation of the PAN NF surfaces. With morphological observation by scanning electron microscopy (SEM), and following further confirmation of the Fourier-transform infrared (FI-IR) spectra of the as-prepared AC-OPNFs, human neural stem cell (NSC) self-renewal is tested, focusing on the relevant discrepancies among the AC-OPNFs, OPNFs, and pristine PAN NFs as flexible cellular matrices. Interestingly, NSCs are attached well on four NFs without conventional coating materials. Self-renewal of NSCs is confirmed by marker expressions such as PAX6 and N-CADHERIN. Among four NFs, FeAC-OPNFs shows the best property of NSC self-renewal. It is expected that AC-OPNFs can be xeno-free and protein-free extracellular matrices for supporting human NSC self-renewal.</P>
Canted slit 형상의 핀틀 인젝터 로켓엔진에서 특성길이 변화에 따른 연소성능
이장환(Janghwan Lee),김완찬(Wanchan Kim),김민석(Minseok Kim),김선훈(Sunhoon Kim),고영성(Youngsung Ko),김형모(Hyungmo Kim) 한국추진공학회 2015 한국추진공학회 학술대회논문집 Vol.2015 No.11
본 연구에서는 케로신과 액체산소를 추진제로 사용하는 핀틀 인젝터의 기초설계자료를 확보하고 설계절차를 확립하여 고정형 핀틀 인젝터를 제작하였다. 이를 적용한 액체로켓엔진의 연소실 특성길이에 따른 연소시험을 통해 연소성능에 관한 연구를 수행하였다. 연소실 특성길이 0.41 m에서 1.07 m까지의 연소시험을 통해 연소성능이 약 90∼95%까지 측정되었으며 추진제 조합에 따른 특성길이 추천치는 1.02~1.27 m이나 특성길이 0.76 m이상에서 최적의 성능을 가짐을 확인하였다. In this study, a fixed pintle injector which uses kerosene and liquid oxygen as propellants was made by collecting basic design data and establishing a design procedure. Combustion performance of the liquid rocket engine was studied by combustion tests for the effect of combustion chamber characteristic length. As a result of hot fire tests, combustion efficiency was measured from 90 to 95 percentage by various characteristic lengths from 0.41m to 1.07m. Also, it showed optimum performance over 0.76m characteristic length, whereas characteristic length of the propellant combinations is recommended from 1.02m to 1.27m.