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( Keun Ho Park ),( Young Keun Ahn ),( Myung Ho Jeong ),( Shung Chull Chae ),( Seung Ho Hur ),( Young Jo Kim ),( In Whan Seong ),( Jei Keon Chae ),( Taek Jong Hong ),( Myeong Chan Cho ),( Jang Ho Bae ) 대한내과학회 2012 The Korean Journal of Internal Medicine Vol.27 No.2
Background/Aims: The aim of this study was to evaluate the impact of diabetes mellitus (DM) on in-hospital and 1-year mortality in patients who suffered acute myocardial infarction (AMI) and underwent successful percutaneous coronary intervention (PCI). Methods: Among 5,074 consecutive patients from the Korea AMI Registry with successful revascularization between November 2005 and June 2007, 1,412 patients had a history of DM. Results: The DM group had a higher mean age prevalence of history of hypertension, dyslipidemia, ischemic heart disease, high Killip class, and diagnoses as non-ST elevation MI than the non-DM group. Left ventricular ejection fraction (LVEF) and creatinine clearance were lower in the DM group, which also had a significantly higher incidence of in-hospital and 1-year mortality of hospital survivors (4.6% vs. 2.8%, p = 0.002; 5.0% vs. 2.5%, p < 0.001). A multivariate analysis revealed that independent predictors of in-hospital mortality were Killip class IV or III at admission, use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers, LVEF, creatinine clearance, and a diagnosis of ST-elevated MI but not DM. However, a multivariate Cox regression analysis showed that DM was an independent predictor of 1-year mortality (hazard ratio, 1.504; 95% confidence interval, 1.032 to 2.191). Conclusions: DM has a higher association with 1-year mortality than in-hospital mortality in patients with AMI who underwent successful PCI. Therefore, even when patients with AMI and DM undergo successful PCI, they may require further intensive treatment and continuous attention.
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Park, Keun-Ho,Ahn, Youngkeun,Jeong, Myung Ho,Chae, Shung Chull,Hur, Seung Ho,Kim, Young Jo,Seong, In Whan,Chae, Jei Keon,Hong, Taek Jong,Cho, Myeong Chan,Bae, Jang Ho,Rha, Seung Woon,Jang, Yang Soo The Korean Association of Internal Medicine 2012 The Korean Journal of Internal Medicine Vol.27 No.2
<P><B>Background/Aims</B></P><P>The aim of this study was to evaluate the impact of diabetes mellitus (DM) on in-hospital and 1-year mortality in patients who suffered acute myocardial infarction (AMI) and underwent successful percutaneous coronary intervention (PCI).</P><P><B>Methods</B></P><P>Among 5,074 consecutive patients from the Korea AMI Registry with successful revascularization between November 2005 and June 2007, 1,412 patients had a history of DM.</P><P><B>Results</B></P><P>The DM group had a higher mean age prevalence of history of hypertension, dyslipidemia, ischemic heart disease, high Killip class, and diagnoses as non-ST elevation MI than the non-DM group. Left ventricular ejection fraction (LVEF) and creatinine clearance were lower in the DM group, which also had a significantly higher incidence of in-hospital and 1-year mortality of hospital survivors (4.6% vs. 2.8%, <I>p</I> = 0.002; 5.0% vs. 2.5%, <I>p</I> < 0.001). A multivariate analysis revealed that independent predictors of in-hospital mortality were Killip class IV or III at admission, use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers, LVEF, creatinine clearance, and a diagnosis of ST-elevated MI but not DM. However, a multivariate Cox regression analysis showed that DM was an independent predictor of 1-year mortality (hazard ratio, 1.504; 95% confidence interval, 1.032 to 2.191).</P><P><B>Conclusions</B></P><P>DM has a higher association with 1-year mortality than in-hospital mortality in patients with AMI who underwent successful PCI. Therefore, even when patients with AMI and DM undergo successful PCI, they may require further intensive treatment and continuous attention.</P>
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김장연,김영조,엄인웅,이동근,이재은 大韓顎顔面成形再建外科學會 1993 Maxillofacial Plastic Reconstructive Surgery Vol.15 No.3
Many surgeons are on the point of bone excision and reconstruction of the bone defects by autograft. xenograft, and allograft in the treatment fo begin and malignant tumors of bone. Of all type of bone grafts, we received the autograft as the best ideal bone graft. Of autogenic bone graft, replantation of excised autogenic bone for reconstructiong the bone defects has been the ideal method until now, but early bone healing reponses and tumor cell devitalization after replantation of excised autogenic bone have not been identified for clinical applications. So, to evaluate bone healing response after replantation in rabbit's calvarial bone, we divided the experimental group into three groups. Group 1 is a fresh autogenous bone group. Group 2 is a deep frozen group. Group 3 is freeze-dried demineralized group. Obtained result were as followed: 1. Inflammatory cell infiltration appeared at I week and disappeared at 4 weeks in all experimental group, Especially, severe inflammatory cell infiltration showed in fresh autogenous bone group at 2 weeks, Especially, severe inflammatory cell infitration showed n fresh autogenous bone group at 2 week Group 3 is the least showing group on the point of inflammatory cell infiltration. 2. Osteoblastic activity evenly increased upto 4 weeks and maintained to 6 weeks and decreased after this period, especially osteoblastic activity in group 2 is less than group 1 and group 3. We can't discriminate between osteoblastic activity of group 1 and that of group 3. 3. In new bone formation, group 3 was more active than any other groups at early stage, but there were little differences among three experimental groups at later state. 4. Bone resorption around the grafted bone slightly appeared at 1 week and disappeared at 4 weeks in all experimental groups. We can find the more bone resorption in group 2 at 2 weeks than any other groups. We could suggest, as appears from our results, that freeze-dried deminiralized bone graft is the useful bone graft in the clinical applications of excised autogenic bone.
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Kim, Joon Young,Jeong, Myung Ho,Ahn, Yong Keun,Moon, Jae Hyun,Chae, Shung Chull,Hur, Seung Ho,Hong, Taek Jong,Kim, Young Jo,Seong, In Whan,Chae, In Ho,Cho, Myeong Chan,Kim, Chong Jin,Jang, Yang Soo,Yo The Korean Society of Cardiology 2011 Korean Circulation Journal Vol.41 No.4
<P><B>Background and Objectives</B></P><P>Patients with renal dysfunction (RD) experience worse prognosis after myocardial infarction (MI). The aim of the present study was to investigate the impact of admission estimated glomerular filtration rate (eGFR) on clinical outcomes of patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation MI (STEMI).</P><P><B>Subjects and Methods</B></P><P>We retrospectively evaluated 4,542 eligible patients from the Korea Acute Myocardial Infarction Registry (KAMIR). Patients were divided into three groups according to eGFR (mL/min/1.73 m<SUP>2</SUP>): normal renal function (RF) group (eGFR ≥60, n=3,515), moderate RD group (eGFR between 30 to 59, n=894) and severe RD group (eGFR <30, n=133). Baseline characteristics, angiographic and procedural results, and in-hospital outcomes between the three groups were compared.</P><P><B>Results</B></P><P>Age, gender, Killip class ≥3, hypertension, diabetes, congestive heart failure, peak creatine kinase-MB, high sensitivity C-reactive protein, B-type natriuretic peptide, left ventricle ejection fraction, multivessel disease, infarct-related artery and rate of successful PCI were significantly different between the 3 groups (p<0.05). With decline in RF, in-hospital complications developed with an increasing frequency (14.1% vs. 31.8% vs. 45.5%, p<0.0001). In-hospital mortality rate was significantly higher in the moderate and severe RD groups as compared to the normal RF group (2.3% vs. 13.9% vs. 25.6%, p<0.0001). Using multivariate logistic regression analysis, adjusted odds ratio for in-hospital mortality was 2.67 {95% confidence interval (CI) 1.44-4.93, p=0.002} in the moderate RD group, and 4.09 (95% CI 1.48-11.28, p=0.006) in the severe RD group as compared to the normal RF group.</P><P><B>Conclusion</B></P><P>Decreased admission eGFR was associated with worse clinical courses and it was an independent predictor of in-hospital mortality in STEMI patients undergoing primary PCI.</P>
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商業係 高等學校 FORTRAN 敎育을 위한 CAI 프로그램의 設計 및 具現에 관한 硏究
홍인식,안종근,장종학 순천향대학교 1994 논문집 Vol.17 No.3
Researching all the kind of CAI studying theory for the efficient teaching-studying at FORTRAN programming language which was important in the computer education of the commercial high school, analized the FORTRAN chapter in the [SUBJECT OF COMPUTER] and [PROGRAMMING]. According to selecting the seven titles and the thirty one subtitles, and made CAI for the FORTRAN language education to provide the efficient teaching materials for the teachers and students. The two groups were made up of 200 students in the 2nd grade. One studied the CAI and the other didn't studied it. The result of the research was as follows : 1. The studying attainment of the group applied CAI is higher than that of the group that not applied CAI. So CAI program is efficient to give rise to interest of studying and to improve the attainment. 2. The attainment improvement of the medium, lower rank students is better than of the high rank student. Therefore, there are much efficiency as to choosing the suitable materials and contents for studying and as to teaching CAI.
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VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구
백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4
It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.
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선택적 LPE방법에 의한 GaAs가판 상의 InP이종접합 박막의 성장
이병택,안주헌,김동근,안병찬,남산,조경익,박인식,장성주,Lee, Byung-Teak,An, Ju-Heon,Kim, Dong-Keun,Ahn, Byung-Chan,Nahm, Sahn,Cho, Kyoung-Ik,Park, In-Shik,Jang, Seong-Joo 한국재료학회 1994 한국재료학회지 Vol.4 No.6
Heteroepitaxial InP/GaAs layers were grown using the selective liquid phase epitaxy (SLPE) technique. It was observed that the optimum LPE conditions were $660^{\circ}C$ growth temperature, $5^{\circ}C$ supercooling, and $0.4^{\circ}C$/min cooling rate. Maximum expitaxial layer overgrowth (ELO) of 110-160$\mu \textrm{m}$ was obtained when the seed was aligned along (112) orientation. Initial melt-back of the substrate was observed but limited to the seed region so that flat In-Ga-As-P layers were grpwn throughout the GaAs substrates. The InP/GaAs heteroepitaxial structure could be obtained by growing an additional InP layer on top of the In-Ga-As-P layer. 선택적 LPE방법을 이용하여 (111)B GaAs 기판 상에 InP연속 박막을 성장하고 그 특성을 평가하였다. 적정 LPE성장조건으로 성장온도 $660^{\circ}C$, 과냉도 $5^{\circ}C$, 냉각속도 $0.4^{\circ}C$/min였으며, 연구된 온도 범위에서 성장온도가 증가할수록 표면형상이 개선되었고 ELO의 넓이가 증가하였다. Seed방향이 <112>방향에서 110-160$\mu \textrm{m}$ 정도의 최대 ELO 넓이가 얻어졌으며 60-80$\mu \textrm{m}$정도의 마스크 간격에서 연속박막을 용이하게 성장할 수 있었다. LPE 성장초기에 기판 용해 현상이 발생하였으며 이에 따라 성장박막의 조성이 대략 $In_{0.85}Ga_{0.15}$As$_{0.01}P{0.99}$으로 변화하고 InP/GaAs계면 및 박막 표면형상이 거칠어졌으나 기판의 성장 부위가 제한됨에 따라 통상적인 LPE박막에 비교하여 매우 개선된 표면형상을 얻을 수 있었다. 두개의 성장융액을 이용하여 1차 박막성장 후 다시 InP 박막을 성장하는 2단성장 방법을 사용하여 순수한 InP/GaAs박막을 성장할 수 있었으며 단면 TEM분석 결과 SLPE성장박막으로 전파하는 활주전위는 산화막 마스크에 의해 효과적으로 차단됨을 알 수 있었다.
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兪長壽,金慶根,金仁洙 대구산업정보대학 1995 논문집 Vol.9 No.2
Deep level in horizontal Bridgman(HB) undoped GaAs were investigated by DLTS system personally manufactured. In as grown sample, T1(E_(C)-0.32eV), T2(E_(C)0.54eV) and T3(E_(C)0.82eV) were observed. These levels correspond to EL6, EL3 and EL2 respectively. As sample was annealed at 650℃, T3 level was separated into T3*(E_(C)0.74eV) and T3 level. When sample was annealed at 800℃, only T3* level was observed. For sample annealed at 900℃, T3* and T3 level were observed. From these results, we conclude that the EL2's behavior of annealing temperature can be explained by the model of As_(Ga)-V_(Ga)-A_(Sl)-V_(As).
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