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위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예
김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2
28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.
Drill가공에 있어서 ADI재료의 절삭성에 관한 연구
조상순,조규재,전언찬,장성규 東亞大學校 大學院 1995 大學院論文集 Vol.20 No.-
The drilling tests were performed on austempered ductile cast irons(ADI) with 2∼3% silicon to clarify the factors influencing the driling characteristics of ADI material. The machinability of each material was evaluated using high speed steel drills of 4mm diameter. The ductile cast iron materials were austenized at 900℃ for 1 hour and then held at 375℃ for 2 hours. Austempered ductile cast iron containsa great deal of retained austenite which contributes to an improvement of impact strength. The machinability of ADI depends on Si components and machinability of workpice has been proved better 3% Si material with high Si components than 2% and 2.5% Si material. It was found that the tool life was a great affected by the feed rate and as feed rate increses, tool life gradually decreased.
김도현,박무인,유찬희,김규종,문원,박선자,장희경 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2
저자들은 65세 남자 환자의 위 중부체부 대만부 전벽에 발생한 점막하 종양에 대하여 3년간 추적관찰 중 크기증가소견으로 쐐기 절재술을 시행하였으며, 조직검사 및 면역 조직 화학 검사에서 위 신경초종으로 진단한 1예를 경험하였기에 보고하는 바이다. Gastric schwannoma is a very rare gastrointestinal benign tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric tumors. We report a case of gastric schwannoma with enlargement of size through serial endoscopic examination. Endoscopic examination showed a hard mass of 4 x 3 cm in size with normal overlying gastric mucosa on the great curvature of the mid-body of stomach. The pathological finding revealed a picture of spindle cell tumor. Immunohistochemical stain was strongly positive for S-100 protein and non-reactive for CD34, C-kit and smooth muscle actin, thus leading to the diagnosis of gastric schwannoma.
이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3
저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.
Jeong Chan-Kyu,Yang Chan-Mo,Lee Sang-Yeol,Jang Seung-Ho 대한우울조울병학회 2022 우울조울병 Vol.20 No.3
Blood valproic acid levels were decreased in patients with traumatic brain injury who had been using valproic acid to control irritability and aggression, and the symptoms worsened coincident with the administration of meropenem, a carbapenem-based antibiotic. Two weeks after the discontinuation of meropenem, valproic acid levels were restored to an effective therapeutic concentration. Therefore, when valproic acid and carbapenem-based antibiotics are used together, blood valproic acid levels may decrease due to drug interaction, and irritability symptoms may worsen. Thus, close monitoring of serum valproic acid levels is required.
[PE-0005] A White Waxy Hybrid Corn, ?Dodamchal? with Good Eating Quality
Sang-Woo Kim(Sang-Woo Kim),Jong Hyeong Lee(Jong Hyeong Lee),Byoung Rourl Choi(Byoung Rourl Choi),Eun Kyu Jang(Eun Kyu Jang),Young Rok Kim(Young Rok Kim),Hae Chan Jung(Hae Chan Jung),Jung-Hee Jang(Jung 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-
Identification of Dinitrotoluene Selective Peptides by Phage Display Cloning
Jang, Hyeon-Jun,Na, Jung-Hyun,Jin, Bong-Suk,Lee, Won-Kyu,Lee, Woong-Hee,Jung, Hyun-Jin,Kim, Seok-Chan,Lim, Si-Hyung,Yu, Yeon-Gyu Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.12
Biomolecules specific to explosives can be exploited as chemical sensors. Peptides specific to immobilized dinitrotoluene (DNT) were identified using a phage display library. A derivative of DNT that contained an extended amine group, 4-(2,4-dinitrophenyl)butan-1-amine, was synthesized and immobilized using a self-assembled monolayer surface on gold. Filamentous M13 phages displaying random sequences of 12-mer peptides specific to the immobilized DNT-derivate were isolated from the M13 phage library by biopanning. A common peptide sequence was identified from the isolated phages and the synthesized peptides showed selective binding to DNT. When the peptide was immobilized on a quartz crystal microbalance (QCM) chip, it showed a binding signal to DNT, while toluene barely showed significant binding to the QCM chip. These results demonstrate that peptides screened by biopanning against immobilized DNT can be useful for quick and accurate detection of DNT.
The Korean Version of Fear of COVID-19 Scale: Psychometric Validation in the Korean Population
Kyu-Sic Hwang,Hye-Ji Choi,Chan-Mo Yang,Jeongwan Hong,Hye-Jin Lee,Min-Cheol Park,Seung-Ho Jang,Sang-Yeol Lee 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.4
Objective Coronavirus disease 2019 (COVID-19) has psychological effects such as anxiety and depression as well as direct infection in people. The Fear of COVID-19 scale is a scale that can measure anxiety related to COVID-19 in a short time. The purpose of this study was to verify the reliability and validity the Korean version of Fear of COVID-19 scale (KF-COVID-19S). Methods The data of total 186 normal adults and 17 patients were finally used for the statistical analysis. For internal consistency, Cron-bach’s α was calculated. For concurrent and discriminant validity, the correlations with the Hospital Anxiety and Depression scale (HADS), Patient Health Questionnaire-15 (PHQ-15), World Health Organization Quality of Life Assessment Instrument Brief Form (WHOQOL-BREF) were analyzed. For construct validity, exploratory and confirmatory factor analysis were conducted. Results Cronbach alpha was 0.88. The two-factor model (factor 1: Physical fear, factor 2: Emotional fear) showed significantly positive correlations and appeared to be “good” fitness (CFI=0.906, IFI=0.907, NFI=0.902). Conclusion The KF-COVID-19S can be a useful scale that can measure the physical and emotional fears associated with COVID-19 in a short time. Because the psychiatric patients are a more vulnerable group to the fear, it is thought that the KF-COVID-19S will help to determine the patient’s level of anxiety and make a therapeutic plan for the underlying mental disorder. Psychiatry Investig 2021;18(4):332-339
급성 경막하 혈종 : 224 수술례 분석 An Analysis of 244 Operated Cases
장호석,이영배,정찬,이규춘,박용석,목진호 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.1
This study is a retrospective clinical analysis of two hundred fourty-four consecutive cases of acute subdural hematoma which were confirmed by operation during the last five years at the Department of Neurosurgery of the Dong-guk University Hospital. The authors have attempted, through this analysis to identify the factors affecting the outcome of acute subdural hematoma. A favorable outcome occurred in 40%, and an unfavorable outcome in 21% of patients at the time of discharge whilea death ocurred in 39% of the cases. We have concluded that initial GCS. pupillary status, systolic arterial blood pressure, FDP vaules, presence or absence of skull fracture. lICP findings on brain CT, hematoma amount and associated intracranial lesions are ail prognostic factors, although the timing of operation did not reflect a significant difference in the outcome, however the sooner the intracranial hematoma lesion is evacuated, the better the outcome will be.