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Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1
Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.
이명호,이재철,이승우,서장일,박세희 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-
폴리머 콘크리트 복합체를 이용하여 악천후에도 시인성이 좋고 주위의 경관과 어울리는 자동점멸 표지병을 개발하였다. 아날로그 회로에 비해 설계상의 난해한 점이 있으나 상대적으로 간편한 디지털 회로를 사용하여 자동점멸 회로를 구성하였으며, 작업의 능률을 높이고 개발비를 줄이기 위하여 OrCAD를 사용한 Simulation을 실시후 회로를 구성하였다. 표지병의 시공시와 같은 환경에서의 실험에서는 디지털회로의 작은 전류와 표지병간의 거리, 전선의 저항으로 인하여 클럭 및 클리어 신호에 전압강하와 상승/하강 시간의 증가가 나타났다. 표지병은 전자회로와 함께 설치되어야 하므로 방수성을 고려하여 표지병과 전자회로를 일체형으로 설계하였다. 실제 시공시의 환경에서 시행한 실험에서 나타난 문제점을 검토하였으며, 향후 연구방향에 관하여 고찰하였다. Using polymer concrete composite, the automatic-on/off road marker that is well distinguished in a bad weather condition of rainy or foggy day and is well harmonized with. Digital circuit that is hard to design but simpler than an analog circuit is used in designing the automatic-on/off circuit, and it order to raise the working efficiency and lower the development cost, OrCAD, a simulation tool of electric circuit, was used in simulating the circuit. In an experiment conducted under the circumstance of practical application, voltage drop and raising/lowering time increment in the clock and the clear signals are occurred because of small current of digital circuit and resistance of electrical line. Because that the road marker is assembled with the digital circuit, it is designed as one assembled unit by considering water proof. Some problems occurred in the experiment and the future work are discussed.
Hybrid Fuel Preparation Combining Glycerol-Derived Hydrogel and Coal and Its Characterization
Park, Se-Joon,Lee, Dong-Wook,Lee, Young-Joo,Bae, Jong-Soo,Hong, Jai-Chang,Kim, Joeng-Geun,Park, Jaehyeon,Park, Jae Hyeok,Shin, Jong-Seon,Choi, Young-Chan American Chemical Society 2013 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.52 No.46
<P>A number of countries are mixing wood biomass with coal in existing coal-fired power plants according to the implementation of renewable portfolio standard (RPS) and cap-and-trade systems; problems arise due to mixing of the two fuels which have different combustion reactivities. In the previous work, research on glycerol impregnated hybrid fuel (Hybrid Coal by Korea Institute of Energy Research; HCK) was conducted for the diversification of bioliquid and issues to be resolved through further study in the application of glycerol to Hybrid Coal were noted. As a solution, a hydrogel having a small quantity of poly vinyl alcohol (PVA) added to glycerol was applied in the present work. PVA allowed the solidification of glycerol and contributed to the binding energy being stronger among glycerol derivatives and the surface of coal pore; thus, the fuel loss by readsorption of water can be inhibited by setting hydrogel into coal pores.</P>
Blood levels of cadmium and lead in residents near abandoned metal mine areas in Korea
Park, Dong-UK,Kim, Dae-Seon,Yu, Seung-Do,Lee, Kyeong-Min,Ryu, Seung-Hun,Kim, Soo-Geun,Yang, Won-Ho,Park, Doo-Yong.,Hong, Yeong-Seoub,Park, Jung-Duck,Lee, Byung-Kook,Moon, Jai-Dong,Sakong, Joon,Ahn, Se Springer-Verlag 2014 Environmental monitoring and assessment Vol.186 No.8
대퇴 전자간 골절의 금속정을 이용한 내고정술 후 실혈량: 위험 인자 분석
박재형 ( Jai Hyung Park ),정화재 ( Hwa Jae Jung ),신헌규 ( Hun Kyu Shin ),김유진 ( Eugene Kim ),박세진 ( Se Jin Park ),고택수 ( Taeg Su Ko ),박종현 ( Jong Hyon Park ) 대한골절학회 2015 대한골절학회지 Vol.28 No.1
Purpose: We compared visible blood loss and calculated blood loss after intramedullary fixation in intertrochanteric fracture, and evaluated correlation between blood loss and its risk factors. Materials and Methods: A total of 256 patients who underwent closed reduction and intramedullary fixation in femoral intertrochanteric fracture between 2004 and 2013 were enrolled in this study. The total blood loss was calculated using the formula reported by Mercuiali and Brecher. We analyzed several factors, including fracture pattern (according to Evansclassification), gender, age, body mass index (BMI), anesthesia method, cardiovascular and cerebrovascular disease, preoperative anemia, American Society of Anesthesiologists (ASA) score and use of antithrombotic agents. Results: Total calculated blood loss (2,100±1,632 ml) differed significantly from visible blood loss (564±319 ml). In addition, the blood loss of unstable fracture patient was 2,496±1,395 ml and multivariate analysis showed a significant relationship between blood loss and fracture pattern (p<0.01). However, other factors showed no statistically significant difference. Conclusion: Total calculated blood loss was much greater than visible blood loss. Patients with unstable intertrochanteric fracture should be treated with care in order to reduce blood loss.
Hee Jin Park,Seung Doh Cha,Hyung Soo Kim,Soo Tae Chung,Noh Hyuck Park,Jeong Hyun Yoo,Jai Hyung Park,Joo Hak Kim,Tae Woo Lee,Chang Hyun Lee,Se Man Oh 대한정형외과학회 2010 Clinics in Orthopedic Surgery Vol.2 No.4
Background: Patients with chronic lateral ankle instability also have peroneal tendinopathy often. However, preoperative MRIs of these patients are vague in many cases. Our study was performed to see the reliability of MRI findings of peroneal tendinopathy in patients with chronic lateral ankle instability. Methods: MRI images for 82 patients who had chronic lateral ankle instability, and had received surgical treatment between March 2006 and November 2009 were compared with impressions from operating rooms. The mean age of patients was 36.4 years (range, 15 to 64 years), 82 ankles were studied, and patients with rheumatoid diseases were excluded from the study. Results: Of the 82 cases, 26 were true positives, 38 true negatives, 13 false positives and 5 false negatives. Of 39 cases of peroneal tendinopathy diagnosed from MRI, 14 had peroneal tendon partial tears, 15 tenosynovitis, 3 dislocations, 17 low-lying muscle bellies, and 6 peroneus quartus muscles. Of 31 cases of peroneal tendinopathy observed in surgery 11 had peroneal tendon partial tears, 4 tenosynovitis, 5 dislocations, 12 low-lying muscle belliess, and 1 peroneus quartus muscle. Sensitivity and specificity of peroneal tendinopathy were 83.9% and 74.5%, respectively. Positive predictive value was 66.7%. Negative predictive value was 88.4%. Accuracy rate was 78.0%. Conclusions: MRI is a useful diagnostic tool for detecting peroneal tendinopathy in patients with chronic lateral ankle instability. However, MRI is vague in many cases. Therefore, a thorough delicate physical examination and careful observation is needed.