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Pathway Enrichment Analysis and Visualization of Transcriptomic Data from BMDC Treated with Fucoidan
Jaeyul Kwon 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Fucoidans, sulfated polysaccharides from brown seaweed, possess a variety of biological activities including antiviral, antioxidant, immunoregulatory, and antitumor function. The mechanisms by which fucoidans interact with antigen-presenting cells remain elusive. Herein, we describe the transcriptional programs induced in bone marrow-derived dendritic cells (BMDCs) by fucoidan. Exposure of BMDCs to fucoidan from brown alga Fucus evanescens led to upregulation of 2,376 gene sets in which 728 gene sets are significant at FDR <25%. Gene lists from RNA-seq experiments were interpreted by pathway enrichment analysis and visualization of omics data using g:Profiler, Gene Set Enrichment Analysis (GSEA), Cytoscape, and EnrichmentMap.
Jaeyul Choo,Jeongki Ryoo,Hosung Choo 한국전자파학회JEES 2011 Journal of Electromagnetic Engineering and Science Vol.11 No.1
In this letter, we propose a novel tag antenna that has low performance degradation with nearby dielectric material. We obtained a stable reading performance and a broad matching bandwidth on nearby dielectric materials by employing a T-matching network with thick line width and capacitively slot-loaded arms. We then built the proposed antenna and measured the tag sensitivity to examine the reading characteristics with nearby dielectric materials. The measured results clearly demonstrate stable tag sensitivity with various nearby dielectric materials, such as foam, acrylic-plastic, glass, and ceramic plates. To more closely observe the antenna characteristics with nearby dielectric materials, we also examined the impedance variation and surface current distribution with respect to the dielectric constant of nearby target objects, which ranged from 1×ε? to 16×ε?.
Lee, Jaeyul,Park, Jaeseok,Faizan Shirazi, Muhammad,Jo, Hosung,Kim, Pilun,Wijesinghe, Ruchire Eranga,Jeon, Mansik,Kim, Jeehyun Elsevier 2019 Infrared physics & technology Vol.98 No.-
<P><B>Abstract</B></P> <P>We demonstrated a preliminary research to investigate the feasible <I>in vivo</I> utilization of swept-source optical coherence tomography (SS-OCT) system with 1310 nm wavelength band to obtain morphological visualizations and human gingival sulcus depth measurements. Apart from the cross-sectional analysis, pixel intensity based OCT image classification algorithm is developed to identify the depth of gingival sulcus quantitatively. A total of 43 sites from the periodontal tissues of five healthy individuals were imaged <I>in vivo</I> by using the OCT system. Two periodontal tissues were right and left maxillary central incisors, while the other four periodontal tissues were left and right mandibular central incisors and later incisors. The developed classification algorithm could measure the gingival sulcus depths, which are 1.15 ± 0.21 mm of the maxilla and 1.06 ± 0.27 mm of the mandible. The averaged total depths obtained by the system was 1.10 ± 0.26 mm. Hence, the gingival sulcus depth could be quantitatively measured by using the swept-source OCT system with the developed image classification algorithm as well as revealing a structural visualization, which ultimately confirmed the potential applicability for gingival sulcus depth real-time assessment.</P> <P><B>Highlights</B></P> <P> <UL> <LI> SS-OCT was utilized to visualize human gingival sulcus <I>in vivo</I> for the depth identification. </LI> <LI> The quantitative measurement was enhanced by applying the developed OCT image classification algorithm. </LI> <LI> Total of 43 sites from the periodontal tissues of five healthy individuals was imaged. </LI> <LI> The classification of gingival sulcus was helpful to confirm the depth of maxilla and mandible regions. </LI> <LI> The proposed method can be anticipated that provides a powerful tool to the periodontal-OCT applications. </LI> </UL> </P>
CHOO, Jaeyul,CHO, Chihyun,CHOO, Hosung 'Institute of Electronics, Information and Communi 2014 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.eb97 No.5
<P>This paper designs tag antennas to satisfy three key goals: mounting on very small objects, extending the reading range with planar structures, and maintaining stable performance on various materials. First, the size of the tag is reduced up to 17% compared to the half-wavelength dipole without a large reduction in bandwidth and efficiency by introducing an inductively coupled feed structure. Second, the reading range is increased to 1.68 times that of the reference dipole tags while maintaining the planar structure using circular polarization characteristics. Finally, a stable reading range is achieved with a deviation in the reading range of only 30% of that of commercial tags on various objects by employing the capacitively-loaded and T-matching network.</P>