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본 실험은 한국 논에서 발생하고 있는 물옥잠의 SU계 제초제에 대한 저항성 메카니즘을 구명하기 위하여 ALS 활성, (¹⁴C]bensulfuron의 홉수이행 및 ALS 유전자의 DNA 염기서열을 분석하였다. 한국 논에서 광범위하게 사용 중인 6 종류의 SU계 제초제들에 대하여 저항성이 확인되었는데, 저항성 생태형에 대한 생체중 50% 저해 제초제 농도(GR??)는 감수성 생태형에 비하여 약 4배에서 64배까지 높았다. SU계 제초제들에 대한 저항성 생태형의 ALS 활성은 감수성 생태형 보다 훨씬 덜 민감하게 반응하였으며, 저항성 생태형에 대한 SU계 제초제들의 I??값은 감수성 생태형 보다 14배에서 76배까지 높게 나타났다. 생태형간 ALS 활성 차이의 원인을 구명하기 위하여 [¹⁴C]bensulfuron의 흡수이행 차이를 조사한 결과 생태형간 뚜렷한 차이가 없는 것으로 나타났다. 그러나 저항성 및 감수성 생태형의 ALS 유전자 염기서열을 분석한 결과 저항성 생태형의 ALS 유전자 아미노산 서열 중 각각 하나의 염기치환에 의하여 168번째 threonine이 serine으로, 189번째 histidine이 arginine로, 247번째 aspartic acid가 glutamic acid로 변이 된 것이 확인되었다. This experiment was carried out to study the resistant mechanism of sulfonylurea(SU) herbicides to Monochoria korsakowii occurring in the rice fields of Korea. The activity of acetolactate syntbase(ALS), absorption and translocation of [¹⁴C]bensulfuron-methyl, and DNA sequence of ALS genes were studied. The apparent SU resiatance to Monochoria korsakowii was confirmed in greenhouse testes. Fresh weight accumulation(GR??) in the resistant biotype was about 5- to 64-fold higher in the presence of six SU herbicides compared to the susceptible biotype. The ALS activity isolated from the resistant biotype to herbicides tested was less sensitive than that of susceptible biotype. The concentration of herbicide required for 50% inhibition of ALS activity(I??) was 14- to 76-fold higher as compared to the susceptible biotype. No differences were observed in the rates of [¹⁴C]bensulfuron uptake and translocation. However, the DNA sequence from the resistant biotype differed from that of the susceptible biotype by single nucleotide substitution at three amino acid each in the middle region excluding the ends of ALS genes. We found three point mutations causing substitution of serine for threonine at amino acid 168, arginine for histidine at amino acid 189, and a aspartic acid for phenylalanine at amino acid 247, respectively, in the resistant biotype.
( Jae-sung Ryu ),( Kyu-tae Chang ),( Ju-taek Lee ),( Malg-um Lim ),( Hyun-ki Min ),( Yoon-ju Na ),( Su-bin Lee ),( Gislain Moussavou ),( Sun-uk Kim ),( Ji-su Kim ),( Kinarm Ko ),( Kisung Ko ),( Kyung- 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.6
The ACKNOWLEDGEMENTS should be corrected as follows, "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea. The published article in this journal was a part of the 2013 Doctoral thesis of Jae-Sung Ryu submitted to Wonkwang University, Korea." and not "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea."
This letter proposes a handover ranging power adjustment scheme to improve handover performance. Incorrect ranging power can degrade handover performance due to the increased handover latency; therefore, the proposed scheme exploits the uplink channel information to adjust the uplink handover ranging power. Simulation results demonstrate that the proposed scheme reduces call outage probability by 33% compared to that of the conventional scheme. It also improves the number of users who satisfy the system requirements for handover interruption time.
본 연구에서는 몇 가지 새로운 집성재 단면구성 방법을 제안하고, 국산 낙엽송과 합판으로 제조된 집성재의 휨시험을 통해 단면 구성에 따른 집성재의 침성능을 평가 비교하였다. 수평적층(BH), 수직적층(BH), 수직으로 합판보강된 수직적층(BVV)과 수평으로 합판보강된 수직적층(BVH)의 총 네가지 형태의 단면구성 방법에 대하여 실험을 실시하였다. 파괴모드를 관찰하고, 실험을 통해 얻어진 하중-변형 곡선으로부터 MOR 및 MOE를 계산하여 이를 바탕으로 각 단면구성 방법의 휨성능 개선효과를 비교하였다. MOR의 경우에는 결함의 분산으로 인해 수직적층에서 수평적층에 비해 23% 정도의 개선효과를 얻을 수 있었으나, MOE의 경우에는 거의 유사한 값을 나타내었다. 수평으로 합판보강된 경우에는 상대적으로 휨성능이 약한 합판이 사용됨에 따라 MOE가 15% 정도 감소하였으나, 수직으로 합판보강된 경우에는 합판이 사용되었음에도 불구하고 MOE의 감소 없이 MOR이 개선되는 효과를 나타내었는데 이는 전단보강의 효과로 생각되며 이러한 효과를 파괴모드의 관찰을 통해서도 확인하였다. 이상의 결과로부터 집성보의 단면 구성시 라미나의 적절한 배치 및 전단보강 등을 통하여 전체적인 휨성능을 향상시킬 수 있음을 확인하였다. In this paper, bending capacities of glulams with different configurations of cross-section were evaluated. These configurations included horizontal(BH), vertical(BVN), vertical with vertical plywood(BVV) and vertical combination of lamination with horizontal plywood(BVH). Full-scale bending tests were performed to investigate the effect of different section configurations on bending strength(MOR) and stiffness(MOE) of glulam. Compared with type BH, MOR of glulam with type BVN configuration was improved about 23%, which was considered to be caused by defect dispersion effect, while MOE of glulams with these two types of configurations were similar. Because MOE of plywood is generally smaller than that of solid wood laminar, MOE of type BVH glulam decreased about 15%, but in the case of type BVV glulam, MOE was improved without any reduction of MOE. The reason of this result could be undersood in the view of shear-reinforcement effect, which was verified from analysis of fracture mode. From the results of this study, it was concluded that bending capacity of glulam could be improved by proper section design, such as laminar arrangement and shear reinforcement.
Objectives : The purpose of this study is to report a 67-year-old male patient with Herpes zoster(caseⅠ) and a 38-year-old female patient with Herpes zoster(caseⅡ), whose symptoms were relieved after Korean medicine treatment alone. Methods : Both patients took Yeonryeonggobondan and Pyungwee-san daily. Everytime they came to the hospital, they received acupuncture treatment, Hwidam's Su-Gi therapy and External Gigong Therapy. Acupuncture was applied by gall bladder seunggyeok(膽勝格, GB-), spleen jeonggyeok(脾正格, SP+), large intestine seunggyeok(大腸勝格, LI-) of Saam's Acupuncture Method. Hwidam's Su-Gi therapy was applied on neck. External Gigong Therapy was applied on skin lesion area. the patients' symptoms were evaluated with photographs and VAS. Results : The results were as follows: 1. In the case of a 67-year-old male patient, it took 14 days to recover the skin lesions and to reduce the pain after treatment started. And he visited 13 times during that period. 2. In the case of a 38-year-old female patient, it took 23 days to recover the skin lesions to reduce and the pain after treatment started. And she visited 10 times during that period. 3. Intensive treatment early in treating herpes zoster helped to shorten the treatment period. 4. Taking Yeonryeonggobondan and Pyungwee-san and receiving acupuncture treatment(SP+) can help to improve immunity and recover skin lesions in herpes zoster diagnosed with spleen deficiency with dampness encumbrance(脾虛濕困) and blood stasis due to qi stagnation(氣滯血瘀). 5. The combination of acupuncture treatment(GB-) and External Gigong Therapy was effective in controlling pain. 6. External Gigong Therapy is considered to be effective for the recovery of the skin as well as the pain of the herpes zoster. Conclusions : Korean medicine treatment alone has a great effect on the above two patients with herpes zoster. I hope the active research about Korean medicine treatment will be done not only for herpes zoster but also for various intractable pain diseases.
Objective: To evaluate the effects of bee venom acupuncture(BVA) on the rehabilitation and quality of life in rheumatoid arthritis(RA) patients Methods: Patients with RA were treated with the BVA therapy twice a week for 3 months. Tender joint counts, swollen joint counts, morning stiffness, Erythrocyte Sedimentation Rate(ESR), C-reactive protein(CRP), patient global assessment, physician global assessment, Korean health assessment questionnaire(KHAQ) were estimated and analyzed before and after BVA therapy. Results: Tender joint counts, swollen joint counts, morning stiffness showed significant decrease after BVA therapy. But, as acute inflammatory reactants, ESR showed no significant difference and CRP showed significant increase after BVA therapy. Patient global assessment physician global assessment, and KHAQ index showed significant improvement after BVA therapy. Conclusions: BVA therapy can improve rehabilitation and health-related quality of life RA patients as well as clinical symptom and signs. Further study is required in more population with large scale including acute inflammatory reaction of BVA therapy.
Objective In order to study the effects of bee venom(BV) on the pain, edema, and acute inflammatory reactant of rheumatoid arthritis(RA) patients. Methods Patients with RA who met the ACR(American College of Rheumatology) 1987 revised criteria for the diagnosis of RA were treated with the BV therapy twice a week for 3 months. Tender Joint counts, swollen joint counts, Visual analog scale(VAS), morning stiffness, ESR. C-reactive protein(CRP) were analyzed before and after BV therapy. Results The results as follows. 1. Tender joint counts in patients after BV therapy were significantly lower than those before BV therapy(9.0±7.9 vs 15± 11.4, p=0.002). 2. Swollen joint counts of the patients after BV therapy were significantly lower than those before BV therapy(50±61 vs 15±23, p=0.001). 3. VAS in patients after BV therapy was significantly lower than those before BV therapy(608± 17.6 vs 380± 159, p=0.000). 4. Duration of morning stiffness in patients after BV therapy was significantly reduced compared with that before BV therapy(119.1± 112.6 min vs 59.0±89.7 min, p=0.009). 5. ESR and CRP were not significantly changed before and after BV therapy, suggesting BV itself could make inflammatory reaction as well as therapeutic effect. Conclusions BV therapy improved tender joint counts, swollen joint counts and duration of morning stiffness in this study, and further study is needed on long-term effect of BV therapy.
Upper gastrointestinal bleeding is common and potentially life threatening medical emergency. Emergency endoscopy is the first choice of diagnostic and treatment measure for patients with active upper gastrointestinal bleeding. Histoacryl should be considered a second-line treatment modality when conventional treatments were failed. However, it might cause several complications. Herein, we report a case of acute pancreatitis developed after histoacryl injection therapy for active duodenal ulcer bleeding. A 71-year-old man was admitted with melena and hematemesis. On emergency endoscopy, a 2 cm sized active ulcer with bleeding from an exposedvessel was seen at the duodenal bulb. Attempts to arrest the bleeding with hemoclipping and submucosal epinephrine injection were tried, but failed. We changed the method to endoscopic histoacryl injection, and obtained hemostasis immediately. A few hourslater, after successful hemostasis, patient complained diffuse abdominal pain. Ultrasonography revealed hyperechoic heterogenous diffuse pancreatic enlargement and right pararenal space fluid collection, this ultrasonographic findings and elevated serum pancreatic enzymes are compatible with acute pancreatitis.
이 논문은 Phase-Locked Loop (PLL) 속도제어계의 계통구성에 의한 위상차검출기를 제작하여 Phase Frequency Detector (PFD)에 의한 오차전압은 Analog Switch 에 의해 정확한 속도 위상차 만을 Microprocessor에 전달하도록 하고, digital controller의 Hard ware를 구성하여 digital filter를 설계하였으며 Analog 제어기법인 PLL의 filter에서의 정상오차를 digital기법에 의해 drift가 없고 주파수 응답특성이 이상적이 될 수 있도록 시스템을 완성 제작하였다. 또한 이 시스템을 이용한 실험을 행하여 고정도(高精度)의 3 상농형 유도전동기 속도제어가 가능하다는 결론을 얻었다. This paper presents a microprocessor-based digital PLL speed control system. In this system digital techniques provide all the funtions such as detection of speed and phase error of the rotor. The Completely digital scheme is free from drift and off-set error which are inherent in an analog circuit, Digital filter using microprocessor are employed. An experimental apparatus including a 0.5 ?? 2 Pole 3 Phase induction motor is concluded that the PLL system of digital fillter using microprocessor is a system with excellent speed regulation.