한국산 하루살이목(目)의 카탈로그

윤일병,배연재,전동준 고려대학교 한국곤충연구소 1994 昆蟲硏究誌 Vol.20 No.1

韓國産 하루살이目의 카탈로그. 裵淵宰 · 尹一炳^1 · 田東埈^2 (서울女子大學校, ^1高麗大學校 生物學科, ^2러시아科學院 動物學硏究所) 昆蟲硏究誌, 20: 31~50, 1994. 韓國産 하루살이目의 關한 硏究는 南北韓에 걸친 綜合的인 硏究가 이루어지지 못하였고, 1940년 以來 各種 文獻에 記錄된 種들에 있어서도 分類上 혹은 命名上 變動이 많았으나 이를 體系的으로 收錄하지 못하였다. 이 論文에서는 種合的인 文獻 및 模式標本 調査를 통하여 다음과 같이 韓國産으로 記錄된 56種의 命名상 有效한 種들에 대한 카탈로그를 작성하였다. Acerella longicaudata(U′eno), *Ameletus costalis (Matsumura), A. montanus Imanishi, *Baetiella japonica (Imanishi), *B, tuberculata (Kazlauskas), *Baetis thermicus U′eno, Bleptus fasciatus Eation, Choroterpes altioculus Kluge, Cincticostella castanea (Allen), C. tshernovae(Bajkova), * Cinygmula grandifaliz Tshernova, *C. hirasana (Imanisht), Cloeon dipterum (Linnaeus), Drunella aculea (Allen), *D. cryptomeria (Imanishi), *D. lepnevae (Tshernova), D. triacantha (Tsher-nova), *D. trispina ezoensis (Gose), Ecdyonurus bajrovae Kluge, E. dracon Kluge, **E. Joernensis mon-golicus Bajkova & Varychanova, E. kibunensis Imanishi, E. levis (Nava′s), E. scalaris Kluge, **E. subspinosa (Braasch & Solda′n), Epeorus curvatulus Matsumura, *E. hiemalis Imanishi, E. latifolium Ue′no, E. pellucidus (Broadsky), *Ephemeralla aurivillii Bengtsson, *E. imanishii Gose, E. keijoensis Allen, *E. notofascia Yoon & Base, Ephemera orientalis McLachlan, E. separigata Bae, E. strigata Eaton, Ephoron shigae (Takahashi), Heptagenia guranica Belov, H. kihada Matsumura, *H. Kyotoensis Gose, *Iron aesculus (Imanishi), *I. koreanicus Braasch & Solda′n, I. maculatus Tshernova, Isonychia japonica (Ulmer), **I. ussurica Bajkova, Paraleptophlebia chocolata Imanishi, *Potamanthellus rarus tiunova & Levanidova, **Potamanthus formosus Eaton, P. yooni Bae & McCafferty, *P. luteus oriens Bae & McCafferty, *Phithrogena japonica Ue′no, Rhoenanthus coreanus (Yoon & Bae), *Serratella setigera (Bajkova), Siphlonurus chankae Tshernova, *S, sanukensis Takahashi 및 Uracanthella rufa (Imanishi). 별표한 種들은 幼蟲만이, 쌍별표한 種들은 成蟲만이 韓國産으로 記載되었다. (C. tshernovae와 E. keijoensis는 암컷 成蟲과 幼蟲만이, 그리고 P. luteus oriens는 亞成蟲만이 韓國産으로 記載되었다.) 다음 10종은 韓國에서 幼蟲만이 記載되었고, 아직 命名上으로 留保된 未決定種으로 남아있다. Baetis Kua: Yoon & Bae, Baetis nla: Imanishi, Brachycercus Kua: Yoon & Bae, Caenis Kua: Yoon & Bae, Cinygmula Kua: Yoon & Bae, Cinygmula na: Imanishi, Ecdyonurus Kub: Yoon & Bae, Ecdyonurus na: Imanishi, Paraleptophlebia nb: Imanishi 및 Rhithrogena na: Imanishi. 각 種에 있어서 原記載 및 再記載 文獻, 記載에 使用된 標本, 分布, 模式標本에 대한 情報, 異名과 命名上의 變動을 年代順으로 整理하였다. 附錄으로 南韓種만의 checklist와 分類學的 變動 및 國名의 變動事項을 表로 作成하였다. Mayflies (Ephemeroptera) of Korea have been described in various literatures since 1940, but there have been many taxonomic or nomenciatural changes in the members of the order. A comprehensive literature and type material review of the Ephemeroptera resulted herein the recognition of 56 nomenclaturally valid species previously described from Korea : Acerella longicaudata (Ue´no), ^*A meletus costalis (Matsumura), A. montanus Imanishi, ^*Baetis thermicus Ue´no, Bleptus fasciatus Eaton, Choroterpes altioculus Kluge, Cincticostella castanea (Allen), C. tshernovae (Bajkova), ^*Cinygmula grandifolia Tshernova, ^*C. hirasana (Imanishi), Cloeon dipterum (Linnaeus), Dyunella aculea (Allen), ^*D. cryptomeria (Imanishi), ^*D. tepnevae (Tshernova), D. triacantha (Tshernova), ^*D. trispina ezoensis (Gose), Ecdynurus bajrovae Kluge, E. dracon Kluge, ^*^*E. joernensis mongolicus Bajkova & Varychanova, E. kibunensis Imanishi, E. levis (Nava´s), E. scalaris Kluge, ^*^*E. subspinosa (Braasch & Solda´n), Epeorus curvatulus Matsumura, ^*E. hiemalis Imanishi, E. latifolium Ue´no, E. notofascia Yoon & Bae, Ephemera orientalis McLachlan, E. separigata Bae, E. strigata Eaton, Ephoron shigae (Takahashi), Heptagenia guranica Belov, H. kihada Matsurnura, ^*H. kyotoensis Gose, ^*Iron aesculus (Imanishi), ^*I. Koreanicus Braaich & Solda´n, I. Maculates Tshernova, Isonychia japonica (Ulmer), ^*^*I. Ussurica Bajkova, Paraleptophlebia chocolate Imanishi, ^*Potamanthellus rarus Tiunova & Levanidova, ^*^*Potamanthus formosus Eaton, P. yooni Bae & McCafferty, ^*^*P. luteus oriens Bae & MeCafferty, ^*Rhithrogena japonica Ue´no, Rhoenanthus coreanus (Yoon & Bae), ^*Serratella setigera (Bajkova), Siphlonurus chankae Tshernova, ^*S. sanukensis Takahashi, and Uracanthella rufa (Imanishi), The asterisked species were known to larva only from Korea, and the double asterisked were adults only (C. tshernovae and E. keijoensis were females and larvae only, and P. luteus oriens was subimagos only), The following 10 species were known to larvae only from Korea, but have not been determined: Baetis Kua: Yoon & Bae, Cinygmula Kua: Yoon & Bae, Baetis nla: Imanishi, Brachycercus Kua: Yoon & Bae, Caenis Kua: Yoon & Bae, Cinygmula Kua: Yoon & Bae, Cinygmula na: Imanishi, Ecdyonurus Kub: Yoon & Bae, Ecdyonurus na: Imanishi, Paraleptophlebia nb: Imanishi, and Rhithrogena na: Imanishi. For each species, original and secondary sources of the descriptions, materials used, type information, distributions, synonyms, aid nomenclatural changes were chronologically provided. A checklist of the Ephemeroptera previously recorded from South Korea was appended with their proposed Korean name.

Phase I/II study of S-1 combined with weekly docetaxel in patients with metastatic gastric carcinoma

Park, S R,Kim, H K,Kim, C G,Choi, I J,Lee, J S,Lee, J H,Ryu, K W,Kim, Y-W,Bae, J-M,Kim, N K Cancer Research UK 2008 The British journal of cancer Vol.98 No.8

We designed a phase I/II trial of S-1 combined with weekly docetaxel to determine the maximum tolerated dose (MTD) and recommended dose (RD) and to evaluate the efficacy and toxicity in metastatic gastric carcinoma (MGC). Patients with measurable disease received S-1 orally b.i.d. on days 1–14 and docetaxel intravenously on days 1 and 8 every 3 weeks. In phase I (n=30), each cohort received escalating doses of S-1 (30–45 mg m<SUP>−2</SUP> b.i.d.) and docetaxel (25–40 mg m<SUP>−2</SUP>); MTD was 45 mg m<SUP>−2</SUP> b.i.d. S-1/35 mg m<SUP>−2</SUP> docetaxel and RD was 40 mg m<SUP>−2</SUP> b.i.d. S-1/35 mg m<SUP>−2</SUP> docetaxel. Dose-limiting toxicities included grade 3 elevated liver enzymes, gastric perforation, grade 3 diarrhoea/fatigue, febrile neutropenia with grade 3 anorexia/fatigue, and neutropenic infection with grade 3 stomatitis/anorexia. In phase II (n=52), the overall response rate was 66.7% (95% confidence interval (CI): 53.8–79.6%) and the median time to progression and overall survival were 6.5 months (95% CI: 4.9–8.1) and 13.7 months (95% CI: 9.9–17.5), respectively. The most common grade 3/4 toxicity was neutropenia (29.4%), and febrile neutropenia/neutropenic infection occurred in 19.6% of patients. Non-haematological toxicities were generally mild. There was one treatment-related death due to pneumonitis. S-1 combined with weekly docetaxel is active in MGC with moderate toxicities.British Journal of Cancer (2008) 98, 1305–1311. doi:10.1038/sj.bjc.6604312 www.bjcancer.com Published online 25 March 2008

원발성 간암에서 PIVKA-II 및 Lens Culinaris Agglutinin-A 반응성 Alpha-fetoprotein(AFP-L3)의 임상적 유용성

배시현,박두호,양진모,박영민,차상복,최종영,성광용,조세현,정규원,선희식,김부성,최상욱,변병훈,한남익 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.2

Background/Aims: Des-γ-carboxy prothrombin(DCP), a protein induced by vitamin K absence or antagonist-II(PIVKA-II), and Lens culinaris agglutinin-A reactive AFP-L3 have been reported to be useful markers for the diagnosis of hepatocellular carcinoma (HCC). In the present study, both the PIVKA-II and AFP-L3 were analyzed and compared with a conventional AFP to determine its usefulness, specificity and sensitivity in the diagnosis of HCC. Methods: Sera were collected from 108 patients consisting of 17 patients with chronic hepatitis, 22 patients with liver cirrhosis and 69 patients with HCC. The AFP-L3 was determined by an lectin affinity electrophoresis coupled with an antibody-affinity blotting. Level of DCP was measured by an enzyme immunoassay with an anti-DCP monoclonal antibody. Results: The sensitivity and specificity of PIVKA-II and AFP L3 were 49.3% and 89.5%, and 32.5% and 85.7%, respectively. No significant correlation was found between the PIVKA-II or AFP L3 and serum AFP. No correlation was found etween the PIVKA-II or AFP L3 and the characteristics of HCC. Conclusion: The determination of plasma DCP and AFP L3 levels combined with AFP levels may be useful especially for the differential diagnosis between HCC and chronic liver diseases without HCC.(Korean J HepatoBackground/Aims: Des-γ-carboxy prothrombin(DCP), a protein induced by vitamin K absence or antagonist-II(PIVKA-II), and Lens culinaris agglutinin-A reactive AFP-L3 have been reported to be useful markers for the diagnosis of hepatocellular carcinoma (HCC). In the present study, both the PIVKA-II and AFP-L3 were analyzed and compared with a conventional AFP to determine its usefulness, specificity and sensitivity in the diagnosis of HCC. Methods: Sera were collected from 108 patients consisting of 17 patients with chronic hepatitis, 22 patients with liver cirrhosis and 69 patients with HCC. The AFP-L3 was determined by an lectin affinity electrophoresis coupled with an antibody-affinity blotting. Level of DCP was measured by an enzyme immunoassay with an anti-DCP monoclonal antibody. Results: The sensitivity and specificity of PIVKA-II and AFP-L3 were 49.3% and 89.5%, and 32.5% and 85.7%, respectively. No significant correlation was found between the PIVKA-II or AFP-L3 and serum AFP. No correlation was found etween the PIVKA-II or AFP L3 and the characteristics of HCC. Conclusion: The determination of plasma DCP and AFP-L3 levels combined with AFP levels may be useful especially for the differential diagnosis between HCC and chronic liver diseases without HCC.(Korean J Hepatol 2000;6:205-214)l 2000;6:205-214)

Camptothecin과 β -lapachone에 의한 혈관주위세포 사멸 기전 연구

이지영,신종욱,배성원,김정미,조계원,조인호 국립보건연구원 2000 국립보건원보 Vol.37 No.-

Syntheses of PCDTBT containing tetrafluorobenzene as electron-withdrawing group with deep HOMO energy level and applications for photovoltaics

Kim, J.,Kim, N.H.,Song, S.,Park, S.Y.,Chae, S.,Bae, E.,Kim, I.,Kim, H.J.,Kim, J.Y.,Suh, H. IPC Science and Technology Press 2016 Polymer Vol.102 No.-

Conjugated polymers using tetrafluorophenylene unit were synthesized and deployed for photovoltaics. The tetrafluorophenylene unit which has the strong electron-withdrawing ability, was utilized for the copolymers of push-pull type with low bandgaps for organic solar cells. 9H-Carbazole as electron-rich unit and di-2-thienyl-2,1,3-benzothiadiazole (DTBT) or tetrafluorophenylene unit as electron-deficient unit were utilized for the syntheses of donor-acceptor (D-A) types of conjugated polymers with different ratios of tetrafluorophenylene unit (PCDTBTF-1, PCDTBTF-3 and PCDTBTF-10). By introduction of tetrafluorophenylene unit in the backbone of PCDTBT, the energy level of the highest occupied molecular orbital (HOMO) and the bandgap were decreased as compared to those of PCDTBT. The higher amount of tetrafluorophenylene unit, the lower energy levels of the HOMO of the polymers were observed. The device of PCDTBTF-1:PC<SUB>71</SUB>BM (1:1) with additive of diphenyl ether (DPE) showed an open-circuit voltage (V<SUB>OC</SUB>) of 0.82 V, a short circuit current (J<SUB>SC</SUB>) of 9.66 mA/cm<SUP>2</SUP>, and a fill factor (FF) of 0.44, which yields PCE of 3.44%.

Simulation study on effect of drain underlap in gate-all-around tunneling field-effect transistors

Lee, J.S.,Seo, J.H.,Cho, S.,Lee, J.H.,Kang, S.W.,Bae, J.H.,Cho, E.S.,Kang, I.M. Elsevier 2013 Current Applied Physics Vol.13 No.6

In this work, the effects of underlapping drain junction on the performances of gate-all-around (GAA) tunneling field-effect transistors (TFETs) have been studied in terms of direct-current (DC) characteristics including on-current (I<SUB>on</SUB>), off-current (I<SUB>off</SUB>), subthreshold swing (S), and I<SUB>on</SUB>/I<SUB>off</SUB> ratio. In addition, the dependences of intrinsic delay time (τ) and radio-frequency (RF) performances including cut-off frequency (f<SUB>T</SUB>) and maximum oscillation frequency (f<SUB>max</SUB>) on gate-drain capacitance (C<SUB>gd</SUB>) with the underlapping were investigated as the gate length (L<SUB>gate</SUB>) is scaled. A GAA TFET with asymmetric junctions, with an underlap at the drain side, demonstrated DC and RF performances superior to those of a device with symmetric junctions.

Effects of Condensed Tannin on the Activity of Ruminal Cellulolytic Bacteria from Korean Native Goats Using Semi-continuous Culture

Choi, J. W 韓國酪農學會 1999 韓國酪農學會誌 Vol.21 No.2

Stent linker effect in a porcine coronary restenosis model

Park, J.k.,Lim, K.S.,Bae, I.H.,Nam, J.P.,Cho, J.H.,Choi, C.,Nah, J.W.,Jeong, M.H. Elsevier 2016 Journal of the mechanical behavior of biomedical m Vol.53 No.-

In this study, we aimed to evaluate the mechanical effects of different stent linker designs on in-stent restenosis in porcine coronary arteries. We fabricated stents with an open-cell structure composed of nine main cells and three linker structures in model 1 (I-type), model 2 (S-types) and model 3 (U-types)) as well as Model 4, which is similar to a commercial bare metal stent design. The stent cells were 70mm thick and wide, with a common symmetrical wave pattern. As the radial force increased, the number of main cells increased and the length of linker decreased. Radial force was higher in model 1, with a linear I-linker, than in models with S- or U-linkers. The flexibility measured by three-point bending showed a force of 1.09N in model 1, 0.35N in model 2, 0.19N in model 3, and 0.31N in model 4. The recoil results were similar in all models except model 4 and were related to the shape of the main cells. The foreshortening results were related to linker shape, with the lowest foreshortening observed in model 3 (U-linker). Restenosis areas in the porcine restenosis model 4 weeks after implantation were 35.4+/-8.39% (model 1), 30.4+/-7.56% (model 2), 40.6+/-9.87% (model 3) and 45.1+/-12.33% (model 4). In-stent restenosis rates measured by intravascular ultrasound (IVUS) and micro-computed tomography (micro-CT) showed similar trends as percent area stenosis measured by micro-CT. Model 2, with optimized flexibility and radial force due to its S-linker, showed significantly reduced restenosis in the animal model compared to stents with different linker designs. These results suggest that the optimal stent structure has a minimum radial force for vascular support and maximum flexibility for vascular conformability. The importance of the effects of these differences in stent design and their potential relationship with restenosis remains to be determined.

Facilitated intracellular delivery of peptide-guided nanoparticles in tumor tissues

Kim, J.H.,Bae, S.M.,Na, M.H.,Shin, H.,Yang, Y.J.,Min, K.H.,Choi, K.Y.,Kim, K.,Park, R.W.,Kwon, I.C.,Lee, B.H.,Hoffman, A.S.,Kim, I.S. Elsevier Science Publishers 2012 Journal of controlled release Vol.157 No.3

Macromolecular nanoparticles can extravasate and accumulate within tumor tissues via the passive targeting system, reflecting enhanced permeability and the retention effect. However, the unsatisfactory tumor therapeutic efficacy of the passive-targeting system, attributable to the retention of extravasated nanoparticles in the vicinity of tumor vessels, argues that a new system that facilitates intracellular delivery of nanoparticles within tumors is needed. Here, we developed hydrophobically modified glycol chitosan (HGC) nanoparticles conjugated with interleukin-4 receptor (IL-4R) binding peptides, termed I4R, and tested them in mice bearing IL-4R-positive tumors. These HGC-I4R nanoparticles exhibited enhanced IL-4R-dependent cellular uptake in tumors compared to nonconjugated nanoparticles, leading to better therapeutic and imaging efficacy. We conclude that I4R facilitates and enhances cellular uptake of nanoparticles in tumor tissues. This study suggests that the intracelluar uptake of nanoparticles in tumors is an essential factor to consider in designing nanoparticles for tumor-targeted drug delivery and imaging.

Safety evaluation of small-break LOCA with various locations and sizes for SMART adopting fully passive safety system using MARS code

Chun, J.H.,Chung, B.D.,Lee, G.H.,Bae, K.H.,Kim, Y.I.,Chung, Y.J.,Kim, K.K. North-Holland Pub. Co 2014 Nuclear engineering and design Vol.277 No.-

A safety evaluation of SMART adopting a fully passive safety system was performed for a small-break loss of coolant accident (SBLOCA) with various break locations and sizes using the MARS code. It is necessary for SMART, adopting a fully passive safety system composed of passive safety injection system (PSIS), automatic depressurization system (ADS), and passive residual heat removal system (PRHRS), to satisfy the passive safety performance requirements, i.e., the capability to maintain safe shutdown conditions for a minimum of 72h without AC power supply or operator action in the case of a design basis accident. A number of SBLOCAs of different locations and sizes were analyzed using the MARS code. The results of the break spectrum analyses showed that the collapsed liquid level inside the core support barrel is maintained high enough above the top of the core owing to the sufficient passive safety injection flow from the core makeup tank (CMT) and safety injection tank (SIT). Therefore, the core is not uncovered for 72h after the break without AC power supply or operator action, resulting in a continuous decrease of fuel cladding temperature throughout the transient.