KI-180과 KI-188 칼슘조성물이 어린쥐의 성장발육에 미치는 영향

박승만(Seung-Man Park),성기승(Ki-Seung Seong),이종석(Jong-Seok Lee),이옥환(Ok-Hwan Lee),한찬규(Chan-Kyu Han) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.3

본 연구에서는 KI-188 칼슘과 KI-180 조성물이 성장발육에 미치는 효과를 조사하였다. 시험기간중 KI-188 칼슘과 KI-180 식이군이 대조군 보다 성장률과 평균 식이섭취량은 증가하였다. 체장은 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 평균 3.55 mm 더 길었고, 등뼈길이는 KI-180 식이군이 대조군 보다 통계적인 차이는 없었지만 0.5 mm 더 길었다. 대퇴골 무게는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 무거웠으며, 대퇴골길이는 대조군에 비해 각각 평균 0.89, 1.09 mm 더 길었다. 혈당, 총콜레스테롤 및 중성지방 농도는 차이가 없었고, 칼슘농도는 KI-188 칼슘과 KI-180 식이군 보다 대조군이 유의하게 높았다. 백혈구와 혈소판수는 차이가 없었고, 적혈구, 혈색소 및 헤마토크릿치는 대조군이 KI-188 칼슘과 KI-180 식이군 보다 통계적으로 높았다. ALP활성은 KI-180 식이군이 대조군 보다 통계적으로 높았고, osteocalcin농도는 KI-188 칼슘과 KI-180 식이군이 대조군에 비해 통계적으로 유의하게 높았다. 혈청 testosterone 농도는 KI-188 칼슘과 KI-180 식이군과 대조군 간에 차이가 없었다. IGF-1과 IGFBP-3 농도는 KI-180 조성물이 대조군 보다 각각 20%, 11% 정도 유의하게 더 높았다. 이상의 결과를 검토할 때 KI-188 칼슘과 KI-180 조성물은 어린쥐의 성장과 골격의 발달을 촉진시키고, 성장호르몬의 분비능을 양적으로 유도하여 전반적인 성장발육에 유효한 작용이 있는 것으로 사료된다. Herbs have active components that promote the growth rate of both animals and human. The KI-180 and KI-188 calcium food formulae contain Acanthopanacis cortex, Bombysis corpus and hoelen, seaweed calcium, chlorella extract, spirulina, colostrum powder, and other natural and functional components. We evaluated the growth-promoting effects of these formulae by analyzing the weight, femur and backbone, alkaline phosphatase, osteocalcin, testosterone, insulin-like growth factor (IGF)-1, and IGF binding protein-3 (IGFBP-3) of growing rats. Growing rats administered with KI-180 and KI-188 calcium showed the increase of body weight, body length, and femur weight and length of growing rats. In addition, administration of KI-180 and KI-188 calcium increased the alkaline phosphatase activity, the levels of osteocalcin and the growth hormones IGF-1 and IGFBP-3 of growing rats. The impact of KI-180 and KI-188 calcium on the physical development of growing rats suggests that the incorporation of these food formulae in the diets of growing children may promote the physical development.

일 대학병원 주차장 유료화에 따른 주차장 이용실태 조사

김정희,박진숙,주찬웅,최기철 한국의료QA학회 1997 한국의료질향상학회지 Vol.4 No.1

Background : As parking problem caused by increasing owner-driver and patients concentration to a general hospital is becoming one of the dissatisfactions in medical care. It is time that a general hospital should solve the parking problem in a desirable way. The purpose of this survey is to let the clients understand the basic motivation of the pay parking and develop the better parking system. Methods : Clients of a tertiary care hospital in Chon-ju were surveyed by means of a questionnaire. All in all, 193, subjects answered the questionnaire. Results : In relation to the previous experiences, 39.6% of the subjects experienced inconvenience with confuse parking lot and the shortage of parking space. Under the were more than those who didn't 62.7% of the subjects answered that the y could find the parking lot easily. 33.2% of the subjects mentioned that it was not easy to drive in the parking area ; The reasons were pointed out the shortage of space, disordered parking, and insufficient guide, 12.8% of the subjects satisfied with the current administering system of parking lot. The outpatients were more affirmative than the admitted patients about the charging system. As for the parking fee, 64% of the subjects answered that it is expensive, and 89.5% of the subjects answered that it is expensive, and 89.5% of the subjects thought imposing of parking fee is irrational. Conclusion : To say as a whole, th basic purpose of the charging system are more of less accepted. However, the management details like parking facilities and payment method are dissatisfactory, so it is necessary to improve the management system. It is also noted that the inpatients showed more negative attitude than the outpatients with the charging system. To secure a more convenient parking, the parking system should be considered in relation to the information service, kind guidance, improve facilities, personnel cooperation, fix outpatient scheduling system. etc.

계획된 행동 이론을 활용한 창원시 불법 주차의식 구조분석

전상민(Sang-Min Jeon),박기준(Ki-Jun Park),송기욱(Ki-Wook Song) 한국자료분석학회 2021 Journal of the Korean Data Analysis Society Vol.23 No.5

과거 주차공간 부족의 문제를 주차시설을 공급함으로써 해결하려 하였으나, 최근에는 환경적 문제·지속가능한 교통적 측면에서 주차수요를 관리해 나가는 형태로 패러다임이 변화하고 있다. 효율적 주차수요 관리를 위해서는 승용차 이용자의 차량 이용실태, 주차의식 조사 등을 통하여 맞춤형 주차관리 정책 수립이 바람직하고, 불법주차에 미치는 운전자의 심리적 변수가 불법주차행위에 어떠한 영향을 미칠 것인지에 대해 ‘계획된 행동 이론(The theory of planned behavior)’을 활용하여 구조방정식을 구축하였다. 분석 결과 불법주차 근절 의지에는 ‘행동에 대한 태도(Attitude)’가 긍정적인 영향을 미치는 것으로 나타났고, ‘지각된 통제감(Perceived behavioural control)’이 부정적인 영향을 미치는 것으로 나타났다. 특히 ‘행동에 대한 태도(Attitude)’ 보다는 ‘지각된 통제감(Perceived behavioural control)’이 불법주차 근절 의지에 더 큰 영향을 미치는 것을 알 수 있다. 향후 불법주차 근절을 위해서는 운전자 심리적 의지를 제어할 수 있는 규범의식, 즉 불법주차로 인한 타인의 피해 정도를 시각화 혹은 계량화할 수 있는 정책홍보 및 상시 주차단속과 같은 강력한 규제정책이 필요할 것으로 판단된다. To manage the demand for parking, it is desirable to establish a customized parking management policy through vehicle usage and parking awareness surveys, and The theory of planned behavior is used to establish a structural equation. The analysis showed that Attitude has a positive effect on the willingness to eradicate illegal parking, and Perceived behavior control has a negative impact. In particular, it can be seen that Perceived behavior control has a greater impact on the willingness to eradicate illegal parking than Attitude. In order to eradicate illegal parking in the future, it is believed that strong regulatory policies such as standard awareness that can control drivers psychological will, i.e., policy promotion and regular parking crackdown that can visualize or quantify the extent of damage caused by illegal parking.

자연친화적인 공원시설 설치를 위한 정책방향 - 국립공원 공원시설의 자연친화성 평가를 근거로 -

박창석,배민기,김태진,Park, Chang-Sug,Bae, Min-Ki,Kim, Tae-Jin 한국조경학회 2009 韓國造景學會誌 Vol.37 No.5

본 연구의 목적은 국립공원 내에 자연친화적인 공원시설의 설계와 설치를 위한 정책방향을 제시하는 것이다. 이를 위해서 국내 외 친환경건물 인증제도와 관련 연구에 대한 고찰을 통해 입지, 설계와 설치, 운영과 관리부분별로 자연친화성 평가지표를 개발하였다. 본 연구에서는 19개 국립공원의 26개 공원사무소에서 실제 시설을 관리하고 있는 공원관리자 79명을 대상으로 한 설문조사를 통해 자연친화성 평가를 위한 자료를 수집하였다. 분석방법은 기술분석, 집단간 평균의 차이분석, 다차원척도법, 요인분석을 활용하였다. 분석결과, 1) 자연친화성 평가지표들 간의 상대적 중요도를 산정한 결과, 시설의 입지 관련지표의 중요도가 가장 높게 나타났다. 2) 공원시설의 자연친화성 수준에 대한 평가 결과, 입지 관련 지표들의 자연친화성 수준이 가장 높게 나타난 반면, 시설의 설계 및 설치 관련 지표들의 수준이 낮게 평가되었다. 특히, 에너지 효율화와 관련된 지표들의 평가값이 가장 낮게 나타났다. 3) 시설별로 보면, 대피소의 자연친화성이 가장 높게 나타난 반면, 휴게소의 자연친화성이 가장 떨어지는 것으로 평가되었다. 4) 전반적으로 볼 때, 설악산, 오대산, 태안해안국립공원의 공원시설에 대한 자연친화성 수준이 높게 나타난 반면, 경주와 속리산 국립공원의 자연친화성 수준은 떨어지는 것으로 평가되었다. 본 연구 결과는 자원절약 및 자연생태계와 공원자원을 보존하고 탐방객의 편리한 이용을 위한 자연친화적인 공원시설 설치를 위한 권고기준을 마련하는데 활용될 수 있을 것이다. The purpose of this research was to propose policy directions for the design and construction of nature-friendly park facilities (PF) in national parks. In order to do that, nature-friendliness evaluation indicators(NEIs) used in green building rating systems and related articles were reviewed. After the initial literature review was complete, NEIs for park facilities based on location, design, construction, operation, and management sectors were developed. Data was obtained through a questionnaire completed by 79 managers at 19 national parks in Korea in 2008. The answers were analyzed using descriptive statistical methods, a t-test, a multi-dimensional analysis, and a factor analysis. This research found that: 1) The results indicated that based on relative weight calculation, the location condition was evaluated as the most important; 2) The evaluation results regarding the degree of nature-friendliness of park facilities showed that location condition was ranked higher than design and construction--in addition, the evaluated values of indicators related to energy efficiency were ranked the lowest; 3) the level of nature-friendliness of shelter was given the highest level, but resting facility was the lowest level; 4) Overall, park facilities at Mt. Seorak, Mt. Odae, and Taean Coast national parks showed high levels of nature-friendliness. But park facilities at Mt. Gyeongju and Mt. Songni national parks showed low levels of nature-friendliness. The results of this research shall contribute to the establishment of tailor-made management policies, the development of detailed guidelines for increased energy efficiency and visitor satisfaction, and the preservation of ecosystems and natural resources in Korea's national parks.

간내 담석과 동반된 간내 담도암에서의 p53과 Ki-ras의 발현

김명환,이성구,서동완,이승규,남승우,박능화,민영일,김연석,심기남,공경엽 대한소화기학회 1997 대한소화기학회지 Vol.30 No.5

Background/Aims: Hepatolithiasis or primary intrahepatic stones may be accompanied later by intrahepatic cholangiocarcinoma. This cancerous lesion is frequently associated with atypical hyperplastic epithelium that was suspected of being precancerous. To investigate the Ki-ras or p53 mutation may play a role in carcinogenesis, and to determine whether atypical hyperplastic epithelium may be precancerous, this study was performed in intrahepatic cholangiocarcinomas associated with hepatolithiasis. Methods: We examined 12 patients with intrahepatic cholangiocarcinomas associated with hepatolithiasis. Ki-ras point mutations were assessed by direct DNA sequencing. Expressions of p53 protein were immunohistochemically assessed. The overexpression of p53 and point mutation of Ki-ras were examined in normal, hyperplastic, atypical hyperplastic, and can- cerous tissues separately. Results: The expressions of p53 protein were detected in 4 (33%) of 12 cholangiocarcinomas and Ki-ras point mutations at codon 12 were found in 2 (17%) of 12 cholangiocarcinomas. In those two carcinoma cases which contained the mutant sequence of Ki-ras, the same point mutation from wild type GGT (glycine) to GAT (aspartic acid) was. found in the associated atypical hyperplastic epithelium. However, none of the normal and hyperplastic epithelium harbored Ki-ras or p53 mutations. Conclusions: The overexpression of p53 may play a part in the carcinogenesis of some intrahepatic cholangiocarcinomas associated with hepatolithiasis, whereas the role of Ki-ras mutations in those cases is dubious. However, Ki-ras point mutation at codon 12 may be responsible for either cancer or atypical hyperplastic epithelium associated with hepatolithiasis in certain cases, suggesting atypical hyperplastic epithelium may give rise to carcinoma.

Development of a Mobile Application, "Wild Flowers of Bukhansan National Park (version 1.0)", for Identification of Plants in Bukhansan National Park

Kim, Sang-Tae,Lee, Seung-Yeon,Kim, Seung-Chul,Byun, Hye-Won,Lee, Sang-Tae,Kim, Mu-Yeal,Hong, Seok-Pyo,Chung, Young-Jae,Park, Ki-Ryong,Lee, Chung-Hee,Lee, Joong-Ku,Heo, Kyeong-In,Lee, Ji-Ye,Lee, Eun-Je National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.3

We developed the educational purpose mobile application, named "Wild Flowers of Bukhansan National Park (version 1.0)", aiming for easy identification of wild flowers for students and visitors in the park. When visitors find a flower or part of plant in the park, visitors can search for its name utilizing the pictures and characters provided in their own smartphone mobile devices or tablet PCs. The application provides pictures of wild flowers in the park and character-based searching system based on 12 diagnostic features (e.g., growth form, leaf arrangement, flower symmetry, petal color, petal number, sepal number, etc). We adopted the complete floristic survey of Chung and Lee (1962) and added species that we confirmed their distribution in the park during the development of this application. In summary, number of vascular plants in this park was estimated to be 428 taxa including 100 families, 280 genera, 327 species, 1 subspecies, 50 varieties, and 5 formas. We provided a total of 588 pictures representing 358 taxa and each taxon includes multiple pictures in many cases. Included identification quizzes can be an efficient educational tool as well as fun activity for students and visitors who are learning plant species in Korea. Our next step will include GPS function in the application for indicating visitor's location and for providing previously reported sites of the species that we interested in the map of the park. The future application which includes GPS function will be a valuable tool for the monitoring of rare plants, plant researches related to the climate changes, etc. We currently provide Korean iPhone version only, and English version and both of android versions will be serviced soon.

Comparison of Proliferative Activity in Each Histological Subtypes of Benign and Atypical Intracranial Meningiomas by PCNA and Ki-67 Immunolabeling

최승진,장은덕,권성오,계대곤,박춘근,이상원,강준기,Choi, Seung Jin,Chang, Eun Deok,Kwon, Seung Oh,Kye, Dae Kon,Park, Choon Keun,Lee, Sang Won,Kang, Joon Ki The Korean Neurosurgical Society 2000 Journal of Korean neurosurgical society Vol.29 No.9

목 적 : 양성 뇌수막종에 비하여 이형성 및 악성 뇌수막종이 나쁜 임상적인 예후 및 양상을 보이는 것은 잘 알려져 있으나, 양성 뇌수막종에 있어서 각각의 병리조직학적 아형에 따른 생물학적 양상의 차이에 대해서는 잘 알려지지 않거나 일부 논란이 되고있다. 본 연구에서는 이형성 뇌수막종 및 양성 뇌수막종의 각각의 병리조직학적 아형에 따른 증식능의 차이여부를 알아보고자 PCNA와 Ki-67표지지수를 분석하였다. 방 법 : 본원에서 뇌수막종으로 수술을 시행하여 얻은, 재발을 보여 재수술을 시행한 2례를 포함하여, 파라핀에 포매시킨 27개의 조직을 대상으로 병리학적인 증식능을 분석하기 위해, PCNA에 대한 단일항체 및 MIB-1 단일항체를 이용한 면역조직화학적 염색을 시행하였다. 조직학적 분류상 meningothelial type이 8례, transitional type이 9례, fibroblastic type이 5례였으며, 이형성 수막종이 5례였다. 결 과 : PCNA표지지수의 평균값은 양성 수막종에서 meningothelial type이 $4.82{\pm}5.10%$, transitional type이 $9.01{\pm}4.25%$, fibroblastic type이 $5.66{\pm}5.32%$를 보였으나 이형성 수막종에서는 $27.62{\pm}19.67%$의 높은 지수를 나타냈고, Ki-67 표지지수의 평균값은 양성 수막종의 아형에서 각각 $0.43{\pm}0.85%$, $0.44{\pm}1.08%$, $0.24{\pm}0.18%$를 보이고, 역시 이형성 수막종에서는 $0.84{\pm}0.59%$의 높은 지수를 보였다. 즉, 양성 수막종에서 각각의 아형에 따른 PCNA 및 Ki-67 표지지수는 통계학적으로 의미있는 차이는 없었으나(p>0.05), 이형성 수막종에서는 의미있는 높은 표지지수를 보여(p<0.05) 양성 수막종에서 보다 높은 증식능을 보임을 알 수 있었다. 결 론 : PCNA 및 Ki-67 표지지수를 이용한 증식능의 비교결과, 양성 뇌수막종에서는 각각의 아형에 따른 생물학적 양상이나 예후는 차이가 없을것으로 생각되나, 이형성 수막종에서는 높은 증식능을 보여 이에 대한 예후를 예상할 수 있을것으로 생각되며, 또한 이러한 표지지수가 병리조직학적으로 양성과 이형성의 감별에 많은 도움이 될것으로 사료된다. Objective : The clinical prognosis and biological behavior of atypical and especially malignant meningiomas are well known to be worse than benign meningioma, but the degree of biological aggressiveness in each classical subtypes of benign meningioma is controversy. This study was performed to see whether there is a difference in the proliferative activity between each different histological subtypes of benign meningioma as well as atypical meningioma. Methods : Paraffin-embedded surgical specimens of 27 meningiomas, including two recurrent tumors, were studied to evaluate proliferative activity by immunohistochemical method with monoclonal antibodies to proliferating cell nuclear antigen(PCNA) and MIB-1. The specimens consisted of 8 cases of meningothelial, 9 cases of transitional, 5 cases of fibroblastic subtypes and 5 cases of atypical meningiomas. Results : Mean PCNA labeling indices of meningothelial, transitional and fibroblastic meningiomas were $4.82{\pm}5.10%$, $9.01{\pm}4.25%$ and $5.66{\pm}5.32%$, but that of atypical meningiomas was $27.62{\pm}19.67%$, noting a higher value compared to all three subtypes of benign meningiomas. Mean Ki-67 labeling indices of the above 3 subtypes were $0.43{\pm}0.85%$, $0.44{\pm}1.08%$ and $0.24{\pm}0.18%$, and that of atypical meningiomas was also revealed to be of higher value ($0.84{\pm}0.59%$). PCNA and Ki-67 labeling indices were not statistically different between histological subtypes of benign meningioma(p>0.05), but the differences of both immunolabeling between benign and atypical meningiomas were statistically significant(p<0.05). Conclusion : Immunolabeling of PCNA and Ki-67 in intracranial meningiomas reveals no prognostic difference between meningothelial, transitional and fibroblastic subtypes in classical benign meningiomas by measuring expression of PCNA and Ki-67, but it seems to be helpful in differentiating benign and atypical meningioma, later showing more proliferative activity and biological aggressiveness.

인체 대장암 및 자궁경부암에서 PCR-SSCP법을 이용한 Ki-ras 암유전자의 점돌연변이에 관한 연구

박영홍,백낙환,김현찬,김상효,홍관희,김기태,이기영 인제대학교 1994 仁濟醫學 Vol.15 No.2

인체 대장암 20례와 자궁경부암 10례의 암조직을 대상으로 c-Ki-ras 유전자 codon 12와 13에서의 점돌연변이를 알아보고자 polymerase chain reaction(PCR)과 single-strand conformation polymorphism(SSCP) 검사법을 시행하였다. 대장암의 경우 20례중 9례(45%)에서, 자궁경부암의 경우 10례중 1례(10%)에서 양성으로 나왔다. 대장암에서는 codon 12에서 GGT가 TGT로의 치환이 4례로서 가장 많았으며, AGT, CGT로의 치환이 각 1례였고 codon 13에서는 GGC가 GAC로의 치환이 2례, TGC로의 치환이 1례인 것으로 나타났다. 자궁경부암의 경우 codon 12에서 GGT가 AGT로의 치환이 1례인 것으로 나타났다. In an attempt to clarify the role of genetic alteration in the genesis of human colorectal and cervical cancers, tissue specimens from 20 patients with colorectal cancer and 10 patients with cervical cancer were examined for the presence of point mutation in K-ras2 exon 1 by single strand conformation polymorphism analysis of PCR product. Exon I of c-Ki-ras2 was amplified by polymerase chain reaction(PCR) and comparison was made between the normal and mutated genes by nondenaturing polyacrylamide gel electrophoresis(PAGE) of PCR product and nucleotide sequence analysis using asymmetric PCR with direct sequencing. Genomic DNA from white blood cells were used as normal control and those from A427 cell line were used as mutated control. 1.PCR product from A427 cell line showed a distinct migration shift pattern compared to the normal control in PAGE and the direct sequencing indicated that nucleotide sequence of codon 12 was mutated from GGT to GAT. In addition, there was a loss of normal allele in A427 cell line. 2.PCR product from 9 cases(45%) out of a 20 colon cancer patients showed migration shifts in PAGE, and all of these 9 patients invariably demonstrated mutation of ras gene, either in codon 12(6 cases:30%) or 13(3 cases:15%). The base substitutions in codon 12 were: from GGT to AGT(1), CGT(1), or TGT(4). Base changes in codon 13 were from GGC to TGC(1) or GAC(2). 3.PCR product from 1 cases(10%) out of a 10 cervical cancer patients showed migration shrifts in PAGE, Invariably demonstrated mutation of ras gene in codon 12. The base substitutions was from GGT to AGT(1) TQE incidence of point mutation of c-Ki-ras in colon cancer was high, however, it was low in cervical cancer, which showed the relation of ruts gene mutation with colon cancer. PCR -SSCP analysis is a simple, rapid and efficient method of detection of point mutation, especially when dealing with multiple samples.

수종의 피부종양에서 Proliferating Cell Nuclear Antigen과 Ki - 67 의 표현에 관한 비교 연구

황선욱(Sun Wook Hwang),원영호(Young Ho Won),전인기(Inn Ki Chun),박창수(Chang Soo Park) 대한피부과학회 1995 大韓皮膚科學會誌 Vol.33 No.3

Background : Both PCNA and Ki-67 have been used as marker for cellular proliferation. The drawback of Ki-67 antibody in immunohistochemistry was that it can be labelled only on fresh tissue, however, MIB1 is a newly developed Ki-67 antiboc which can be labelled on formalin-fixed tissue. Objective : The purpase of the present study is to compir the stainability of the Ki-67 antibody with that of the ICNA antibody on formalin-fixed, para fin embedded tissues. Methods : Using MIE1, the newly developed Ki-67 antibody and PC10(PCNA antibody), speci mens of squamous cell carcinoma(SCC), Bowens disease(BL), actinic keratosis(AK) and basal cell epithelioma(BCE) were stained by one hour immunocytial, mistry using a Microprobe immuno/DNA stainer. Results : The labelling indices (LI) of MIB1 were 82.6%, 37.4%, 38.3% & 81.1% respectively in SCC, BD, AK & BC, while the LI of PC10 were 77.69%, 26.6% & 64.4%. The labelled cells of both antibodies differed in distribution patterns on turmor tissues. Conclusion : MIBI cain be used to be an alternative m.rl r for proliferating cells. MIBI PC10, when used together, will be mutually compensatory the study of proliferating cell kinetics. (Kor J Dermatol 1995;33(3): 453-458)

박인환 시에서의 우울과 시간의식

박슬기(Park Seul-ki) 한국시학회 2012 한국시학연구 Vol.- No.33

박인환 시에 만연한 우울과 슬픔의 감정은 허무와 죽음의식을 나타내는 것으로 평가되어 왔다. 초기 시에서 보였던 현실 지향적 의식이 전쟁을 경험하면서, 내면으로 침잠하는 페시미즘의 성향을 보이는 것으로 평가되어 왔다. 그러나 이 슬픔과 우울의 감정은 박인환의 시에서 시간의식과 밀접하게 관계되어 나타난다는 점에서, 역사적인 것으로 이해되어야 한다. 말하자면, 전쟁이라는 매우 구체적인 폭력의 현상을 목도하고 경험하는 순간에 얻어지는 감정은 이 경험의 순간을 역사적으로 고찰할 수 있는 판단력에 해당한다. 박인환의 시는 초기의 현실 지향적 경향에서 후퇴하여 내면으로 침잠한 것이라기보다는, 이 순간의 적극적인 인식을 통해서 여전히 현실에 대응할 수 있는 시의 가치를 견고하게 지켜내고자 했다고 할 수 있다. '우울'이라는 감정의 적극적 노출은 그가 페시미즘에 빠졌다는 것을 의미하는 것이 아니라, 당시에 전쟁을 대한 다른 사람들과 다른 위치에서 있었다는 것을 의미한다. 박인환의 시에서 시간은 적극적인 '현재'의 시간, '순간'의 시간이며, 이는 그러한 시간선 위에서 빠져나오는 것을 의미하기 때문이다. 박인환은 진보적 시간관에서 빠져나와 '순간'에 적극적으로 서는 것으로써 자신의 전쟁경험을 구성하고, 그것에 의미를 부여하려고 한다. '우울'은 전쟁이라는 당면한 역사적 비극 앞에서 그것을 '판단'하고 그 자리에서 '인간의 가치'를 찾아보려는 노력에 수반하여 나타났다. 비록 박인환은 요절함으로써 그 시적 성취를 끝까지 끌고 가지는 못했지만, 1950년대에 만연한 '감정'의 문제를 새로운 차원에서 바라볼 수 있는 단초를 마련하고 있다고 평가할 수는 있을 것이다. The overflowing emotions of melancholy and sorrow in Park, In-hwan's poems has been interpreted as his consciousness of the death; his keen attention toward the reality seems to have been transformed into pessimistic attitude, which turned him to the interior after he experienced the Korean war. However, in the sense that those emotions of melancholy and sorrow are in close connection with the poet's unique concept of time, we have to understand those as something with its own historicity. Park construes historical time through the moments and achieve the positive attitudes through his poetic method of recollection. He makes the past present through the recollection; what is not existent any more is associated with the present through this poetic imagination, and this allows humans to be saved from the momentary despair. The positive exposure of the melancholic emotion in his poems does not mean that he indulged himself with pessimism; it means that he took the different position toward the war from others. In his poems, time is always the time of the positive present and this unique conception allows him to break away from the general concept of the linear flow of time. Park tries to construct and reevaluate what he experienced at the war while positioning himself at the positive moments with escaping from the conceptual framework of the progressiveness of time. The melancholy is accompanied with Park's struggle to understand the historical tragedy of the war and to discover the human values at its site. Though Park's untimely death prevented him to take this poetic achievement to another level, his poetics allows us to comprehend the issue of overflowing emotions in the post-war Korean poetry from a new angle.