당뇨병유발백서에서 급성패혈증 병발시 적혈구막지질과산화의 변화

박성우,홍성관,유형준,장대영,강승식,유재명,임성희,최문기,노정우,이규만 대한당뇨병학회 1994 Diabetes and Metabolism Journal Vol.18 No.3

인공판막 재대치험예에서의 판막실패의 양상

박영배,김유호,서정돈,최윤식,이영우,오병희,도문홍,최동주,전은석 대한내과학회 1987 대한내과학회지 Vol.32 No.3

In order to observe the aspects of prosthetic cardiac valve failure, we analyzed 26 cases of Redo operation among 1081 cases of valve replacemant performed from Jan. 1961. to July 1986. The results are as follows; 1) Crude Redo operation rate was 2.4%. 2) The most common cause or prosthetic cardiac valve failure was the primary tissue failure (73%) 8r the PVE was the 2nd (15.4%). 3) Mean valve implantation time was 47.7 months. Implantation time in the child group was shorter than in adult by 6.8 months, In the primary tissue failure group (19 cases) implantation time in the child was 42.8 months 8z in adult, 66.8 months. (P$lt;0.05) In conclusion, the durability of tissue valves was significantly decreased in the child age group because of increased propensity for calcification, so the preference of tissue valves especially in this age group should be reconsidered.

프로골프선수의 슬관절 등속성 근력에 관한 굴곡근과 신전근의 비교연구

박성태,정성태,정덕조,정영수,엄우섭,전태원,우재홍,박익렬 한국운동과학회 2000 운동과학 Vol.9 No.1

프로골프선수의 슬관절 등속성 근력에 관한 굴곡근과 신전근의 비교연구. 운동과학, 제 9권 제 1호. (201)-(209), 2000. 본 연구는 장기간의 골프운동이 슬관절의 단축성 굴근력과 신근력의 발달에 미치는 영향을 규명하여 경기력 향상을 위한 트레이닝 방법의 기초자료를 제공하고자 수행 되었다. 연구의 대상은 24명의 프로골프선수들(29.60±3.8세)로 골프경력은 12±1.7년으로 대상자 전원이 오른손을 주로 사용(우타)하였다. 측정은 등속성근력계(Cybex 770)를 이용하여 각속도 60°/sec와 180°/sec에서 3회씩 좌·우 교대로 측정하였다. 측정변인은 peak torque, peak torque 발현각, 평균파워, 총운동량 등이었다. 자료분석은 SPSS통계프로그램을 이용하여 실시하였으며 다음과 같은 결론을 얻었다.; 슬관절 굴곡근과 신장근의 좌·우 근력 비교에서 각속도 180°/sec로 굴곡성 운동시 총 운동량(total work)에서 좌·우측간에 유의한 차이가 있는 것으로 나타났으나(p<.05), 나머지 측정변인에서는 굴곡근과 신전근 모두 부하각속도에서 통계적으로 유의하지 않았다. 굴곡력의 경우 우측하지가 좌측하지에 비하여 높았으나 신전력의 경우 좌측하지가 다소 높은 경향을 보였다. 각 변인의 평균치에 대한 60°/sec와 180°/sec간의 비교에서는 모든 변인에서 통계적으로 유의한 차이를 나타내었다(p<.05). 슬관절 굴곡근의 신전근에 대한 비율(Flexor/Extensor Ratio)은 60°/sec에서 60%보다 낮게 나타났으나 좌·우측간 유의하지는 않았다. 결론적으로 다년간의 골프운동은 하지의 슬관절 근기능을 발달시키며 우측하지에 비해 좌측하지의 신전근에 더 많은 발달을 가져온다고 할 수 있다. A study on isokinetic concentric torque of kee extensor and flexor in golf players. Exercise Science, 9(1): 201-209, 2000. The purpose of this stydy was to investigate the effect of long therm golf exercise on isokinetic concentric torque of kee extensor and flexor. The subjects of this study were 24 men progolf players(29.60±3.8yrs) who have experience of 12±1.7yrs golf exercise and use mainly a right hand. The measurement was performed by use of Cybex 770 in angular velocity 60˚ /sec, 180˚ /sec and 3 repetitions. The variable of measure were peak torque, angle of peak torque, average power, total work and so on. The result of this study were as follow: There only was statistical difference between both low limb in Total work of knee flexor in angular velocity 180°/sec(p<.05) but not in other variables in both angular valocity. Right low limb was little stronger than reft low limb in flexor but there was opposite result in extensors. There was statistical difference between 60°/sec and 180°/sec in all varible. Knee flexors and extensors ratio was lower than 60% in angular velocity 60°/sec but there was no statistical difference between right and left low limb. It might be concluded from the test that long term golf exercise strengthen muscle function of knee flexors and extensor and left knee extensors more strengthen than right knee extensors.

급성 심근경색증 초기 진단에 latex 응집을 이용한 혈청 myoglobin 측정의 임상적 의의

박영배,서정돈,최윤식,이영우,오병희,손대원,임하진,김유우,박명희 대한내과학회 1987 대한내과학회지 Vol.32 No.2

We evaluated the diagnostic usefulness of latexagglutination test for elevated serum myoglobin as a screening test in the early phase of acute myocardial infarction and 21 patients with chest pain mimicking acute myocardial infarction were included in this study. Result was compared with serum myoglobin level measured by radioimmunoassay (RIA) in every case. The Following results were obtained: 1) When serum myoglobin levels measured by RIA below 85ng/㎖ were regarded as normal, this test showed sensitivity of 82%, specificity of 95%. 2) In latex-agglutionation test for elevated serum myoglobin, test results were interpreted as negative, weakly positive and positive. If we regard weakly positive tests as positive, sensitivity was 93% and specificity was 62%. In contrast, if we regard weakly positive tests as negative specificity rose to 100% while sensitivity reduced to 75%. 3) Agreement rate of both test was k=0.59. It is suggested that latex-agglutination test for elevated serum myoglobin is helpful in ruling out acute myocardial infarction when test result is negative, and that it can be used as a screening test in the early phase of acute myocardial infarction because of its rapidity and simplicity in performing the procedure.

제왕절개수술에서 저혈압 예방을 위한 수액의 비교 관찰 : 제 1 보:척수마취

심재철,김완식,박동호,황영희,김흥대,김지영,차영덕,서병태 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.3

Rheomacrodex-D 10% W/V in dextrose (500 ml) was prophylactically infused before anesthesia over 15 to 20 minutes to prevent hypotension during spinal anesthesia in 20 patients undergoing elective Casarean section. Apgar scores and the incidence and severity of hypotension were compared to results obtained in 20 patients who were given 500 ml of Hartmann's solution. The results were as follows; 1) Mean arterial pressure decreased up to 20 torr from control values in patients hydrated with Hartman's solution and also changed significantly in patients given Rheomacrodex-D (p<0.05). 2) The incidence and severity of hypotension at 10 minutes, and 15 minutes, and 15 minutes after spinal anesthesia (p<0.05) was significantly less in patients given Rheomacrodex-D than in patients hydrated with Hartmann's solution 3) The Apgar scores, both at 1 minute and 5 minutes, were significantly higher (p<0.05, p<0.005) in infants born of mothers given Rheomacrodex-D than in infants whose mothers were given Hartmann's solution. 4) The cases of hypotension defined as a descrease in systolic arterial pressure lower than 100 torr or a decrease in mean arterial pressure to 25% from control values were 12 cases in 20 patients hydrated with Hartmann's solution and 6 cases in 20 patients given Rheomacrodex-D.

소아마취의 임상통계학적 고찰

김완식,박동호,황영희,김흥대,안기량,석민호,김지영,장경덕,서병태 대한마취과학회 1982 Korean Journal of Anesthesiology Vol.15 No.1

Midazolam maleate, a water soluble banzodiazepine unlike diazepam, was synthetized by Walser and Fryer in 1975. In order to ealuate the effectiveness as an induction agent for general anesthesia, 22 elective surgical patients belonging to ASA classification 1 and 2 were selected. And ten patients (male 7, female 3, average 33.5 years old) were induced with midazolam maleate 0.2mg/kg and twelve patients (mdale 7, female 5, average 32.5 years old) with diazepam 0.3mg/kg. The results were summarized as follows. 1) Anesthesia was induced in all of midazolam group by one intravenous injection, but only 6 patients of diazepam group could induced by one injection and the other 6 patients needed 2 or more injections. 2) The changes of blood pressure and pulse rate after induction and intubation were almost similar in the two groups, but greater individual variation was seen in diazepam group. 3) A buring sensation following intravenous injection was noted in 11 cases of diazepam group, but none in midazolam group and no phlebitis in either group. From the above results, diazepam and midazolam are almost similar in nature but midazolam is definitely effective as an induction agent and has less side effects. Therefore midazolam maleate is regarded as a more effective agent than diazepam as an induction for general anesthesia.

소장내용물의 위내역류 및 위내용물 배출시간에 관한 연구

김진호,박승철,이형호,안일민,박영태,김열흥,이창흥 대한내과학회 1986 대한내과학회지 Vol.30 No.2

Radionuclide enterogastric scintigraphy was done with (99m)Tc-DISIDA and (111)In-DTPA in 35cases; control group 5, gastric ulcer group 6, subtotal gastrectomy with Billroth g group 5, and functional gastrointestinal disorder group with or without grossly mixed bile in the gastric juice 19 cases. The results were: 1) Enterogastric reflux was very significantly increased in the subtotal gastrectomy with Billroth II group (p$lt;0, 001), 2) Gastric emptying was significantly delayed in the functional gastrointestinal disorder groups with or without grossly mixed bile (p$lt;0.05, p$lt;0. 001). 3) Enterogastric reflux was not significantly increased in the gastric ulcer group. 4) Enterogastric reflux was not significantly different between the functional gastrointestinal groups with or without grossly mixed bile in the gastric juice. 5) Inverse correlation between the gastric emptying indices and the enterogastric reflux indices was not proved (r=-0.37).

배양된 혈관내피세포에서 uncoupling protein 2 유전자 과발현이 세포내 산화스트레스 및 endothelin - 1 mRNA 발현에 미치는 영향

강효경,한정희,홍성관,김하영,남궁일성,박기영,박혜선,이재담,박중열,이인규,이기업 한국지질학회 2001 韓國脂質學會誌 Vol.11 No.2

운동후 측복통과 함께 발생한 급성 신부전 1 예

김종순,박영주,조종태,이정임,신민호,구천희,박태용,한승수,강진화 대한내과학회 1996 대한내과학회지 Vol.50 No.6

We report a case of acute renal failure with severe loin pain and patchy renal vasoconstriction after exercise. An immediate postcontrast computed tomogram of this case shows multiple patchy areas of poor contrast enhancement in the cortex of the both kidneys. A 24-hours delayed scan without further injection of contrast dye shows multiple wedge-shaped contrast enhancement in the coincident areas of poor enhancement in the immediate scan. The 2 and 5 days delayed scans show that wedge-shaped contrast enhancement becomes disappeared gradually to the renal cortex, and the 8 days delayed scan shows complete disappearance of contrast enhancement. The renal scintigrams with technetium-99m-methylene diphosphonate and dimercaptosuccinic acid show diffuse increased uptakes and multiple patchy photon deficient areas in the both kidneys respectively. The follow-up renal scintigrams show nearly normal findings, This patient had an uneventful hospital course and recovered completely without dialysis.

가성 장폐쇄로 발현한 부신경절종 1 예

김용태,이기업,박건춘,송영기,이문호,유은실,이준호,진태선 대한내과학회 1991 대한내과학회지 Vol.40 No.5

Phenochromocytoma is a catecholamine-secreting tumor, most of which grow at the adrenal gland. About 109p Of pheochromocytomas are detected at the extra-adrenal chromaffine tissues and are called paraganglioma. The main symptoms of pheochromacytoma include hypertension, headache, palpitation, and sweating. Gastrointestinal symptoms such as abdominal pain, constipation, and vomiting are found in 20∼40% of patients with pheochromocytoma, but these are usually overlooked because of the severe, prominant cardiovascular symptoms. Intestinal pseudo-obstruction without hypertension in pheochromocytoma is very rarely found. It is caused by the decreased motility of the intestine and the over-contraction of the intestinal sphincter, which are caused by the unbalanced activation of α-and β-adrenal receptors. It can be hypothesized that catecholamine receptors in the cardiovascular system are down-regulated or desensitized, but those in the intestine remain intact. We report herein a case of pheochromocytoma in which intestinal pseudo-obstruction was the main presenting clinical manifestation. Symptoms of intestinal pseudo-obstruction were completely relieved by administration of phenoxybenzamine, an α-receptor blocker, and excisional surgery.