경막외마취 확산의 비교관찰 제 1 보 Bupivacaine-Lidocaine

김영석,김완식,김인규,김흥대,안기량,김교상 대한마취과학회 1980 Korean Journal of Anesthesiology Vol.13 No.1

Epidural anesthesia is widely practiced for lower abdominal operation and delivery in many hospital and its complication in minimal compared with spinal anesthesia. Lidocaine has been used extensively for epidural anesthesia with very satisfactory results. It has a very rapid onset of action, producing complete analgesia and has a reasonable duration of action(about 1-1½hr). A concentration of 1. 5% lidocaine causes effective sensory and autonomic blockade but it is unlikely to produce motor paralysis. More recently, bupivacaine(0.5%) has tended to supplement lidocaine as the drug of choice of epidural anesthesia. Firstly, the duration of action is longer. Secondly, it has better affinity for the tissue so that less will be absorbed into the circulation, thus reducing the risk of a toxic reaction. Thirdly, when used with a continuous technique, there is much chance of tachyphylaxis. Using a standardized anesthesia technic, we compared level of sensory anesthesia with a 0. 5% bupivacaine and 1. 5% lidocaine uder elective and emergency surgery. When equal volume of local anesthetic solution were injected(20 ml of 0.5% bupivacaine and l. 5% lidocaine) there were no statistically significant differences in sensory level in bupivacaine and lidocaine, but the duration of anesthesia in bupivacaine from 2 to 3 times longer than lidocaine.

가성 장폐쇄로 발현한 부신경절종 1 예

김용태,이기업,박건춘,송영기,이문호,유은실,이준호,진태선 대한내과학회 1991 대한내과학회지 Vol.40 No.5

Phenochromocytoma is a catecholamine-secreting tumor, most of which grow at the adrenal gland. About 109p Of pheochromocytomas are detected at the extra-adrenal chromaffine tissues and are called paraganglioma. The main symptoms of pheochromacytoma include hypertension, headache, palpitation, and sweating. Gastrointestinal symptoms such as abdominal pain, constipation, and vomiting are found in 20∼40% of patients with pheochromocytoma, but these are usually overlooked because of the severe, prominant cardiovascular symptoms. Intestinal pseudo-obstruction without hypertension in pheochromocytoma is very rarely found. It is caused by the decreased motility of the intestine and the over-contraction of the intestinal sphincter, which are caused by the unbalanced activation of α-and β-adrenal receptors. It can be hypothesized that catecholamine receptors in the cardiovascular system are down-regulated or desensitized, but those in the intestine remain intact. We report herein a case of pheochromocytoma in which intestinal pseudo-obstruction was the main presenting clinical manifestation. Symptoms of intestinal pseudo-obstruction were completely relieved by administration of phenoxybenzamine, an α-receptor blocker, and excisional surgery.

한국산 날치과(Beloniformes , Exocoetidae)어류 5 종의 분류학적 재검토

김종만,김진구,유정화,조선형,명정구,강충배,김용억 한국어류학회 2001 韓國魚類學會誌 Vol.13 No.2

Taxonomic review of the five flyingfishes, Parexocoetus mento (Valenciennes), Cheilopogon agoo (Temminck et Schlegel), Cheilopogon heterurus doederleini (Steindachner), Cheilopogon cyanopterus (Valenciennes), Hirundichthys oxycephalus (Bleeker) were carried out based on samples collected from the South sea and around sea of Jeju Island of Korea from 1996 to 1998. Parexocoetus mento (Valenciennes) and Cheilopogon cyanopterus (Valenciennes) were revealed as the unrecorded species in Korea, which were named as "Men-to-hwang-nal-chi" and "Ki-geom-nal-chi" respectively. Parexocoetus mento is differed from P. barchypterus in having no chin barbels in juveniles, and Cheilopogon cyanopterus is distinguished from C. agoo in the branched form of pectoral fin rays and from C. heterurus doederleini in the numbers of the dorsal fin ray and the color of pectoral fins.

실리콘 직접 접합/전기화학적 식각정지를 이용한 실리콘 다이아프램의 형성과 실리콘 압력센서 제조에의 응용

김성환,주병권,김철주,차균현,오명환,하병주,김근섭,송만호 한국센서학회 1994 센서학회지 Vol.3 No.3

A new type of Si diaphragm was fabricated using Si-wafer direct bonding and two-step electrochemical etch-stopping methods. Using the new diaphragm structure in mechanical sensors, more precise control of cavity depth and diaphragm thickness was achievable. Also, the propagation of the stress, which was generated near the bonding interface, to the surface can be avoided. Finally, a piezoresistive-type Si pressure sensor was fabricated utilizing the diaphragm and a digital pressure gauge, which can display units of pressure, was realized.

육성돈에서 Phytase 첨가가 Extrusion 한 쌀겨의 P 이용성에 미치는 영향

김영길,김인호,손중천,김은주,권기범,문태현 한국영양사료학회 1999 韓國營養飼料學會誌 Vol.23 No.3

본 시험은 육성돈에 있어 extrusion된 쌀겨에 대한 P의 이용성과 extrusion된 쌀겨에 phytase를 첨가하므로서 P의 이용성에 미치는 영향을 구명하고자 영양소 소화 시험을 실시하였다. Extrusion된 쌀겨와 extrusion된 쌀겨에 phytase을 첨가한 구간의 비교는 phytase의 첨가에 의해 건물 소화율이 약간 증가하는 경향을 보였다(P<0.04). N 소화율은 쌀겨구 보다는 extrusion된 쌀겨구에서 약간의 증가를 보였다(P<0.07). Ca(P<0.06)과 P(P<0.01)의 소화율은 모두 extrusion된 쌀겨에 phytase의 첨가수준이 다를 경우 500 unit보다는 1,000 mini에서 더 좋은 효과를 보였다. 분 중 P 배설량(2.72g/d vs 3.89g/d)은 extrusion된 쌀겨보다는 extrusion된 쌀겨에 phytase을 첨가하므로서 줄어들었다(P<0.08). 또한 phytase의 첨가수준이 증가할수록 P의 축적량이 증가함을 알 수 있었다(P<0.04). 한편 Ca 섭취량, 배설량 및 축적량은 모든 처리구 간에 통계적인 유의성을 찾아볼 수 없었다. 그러나 최종 Ca 축적량은 쌀겨에 비해 extrusion된 쌀겨의 경우 15%가 향상되었다(6.64g/d vs 5.77g/d). An experiment was conducted to determine the effects of microbial phytase and feed processing on production and phytate P utilization of pigs. Four crossbred barrows with average initial body weight of 30㎏ were used in 24-d metabolism experiment(4 x 4 latin square) to determine the effect of extruded rice bran and phytase supplementation on nutrient utilization. Digestibility of DM in pigs fed extruded rice bran with phytase improved compared to that in pigs fed extruded rice bran(P<0.04). N digestibility was greater for extruded rice bran than rice bran(P<0.07). However, there was no effect of phytase supplementation to extruded rice bran. Digeshbilities of Ca(P<0.06) and P(P<0.01) were greatest for extruded rice bran with phytase 1,000 unit. Fecal excretion of P(2.72g/d vs 3.89g/d) was less for extruded rice bran with phytase than without phytase(P<0.08). Also, when phytase supplementation was increased in diet, there was increased P retention(P<0.04). There were no treatment effects intake, excretion and retention of Ca. However, Ca retention improved by 15% in extruded rice bran compared to rice bran(6.44g/d vs 5.77g/d).

보행마취(步行麻醉)

김영석,김완식,황호성,이진근,유희구,김흥대 대한마취과학회 1977 Korean Journal of Anesthesiology Vol.10 No.2

An imaginative innovation to shorten hospital stays as a means to reduce patient charges, is out-patient surgery. This procedure also minimized the inconvenience and disruption of the family unit, reduced the opportunities for cross-infection, and freed hospifal beds for the more serriously ill patienta Since the concept of out-patient surgical service was organized, managed, and performed in the Hanyang Medieal Center, we had experience of 132 ambulatory anesthetics during the last two years (from Jan. 1974. to Dec. 1975 ). The results are summarized as follower 1. Preanesthetic examination should be routinely cheeked with Hb., Hct., urinalysis and chest x-ray. 2. Premedication should be administered preanesthetically, atropine sulfate intravenously. 3. ASA class 1 patients should be rhnsen fnr short (less than 1 hour) procedures. 4. Anesthesia is induced with Epontol+S.C.C. and maintained with Halothane+N2O+O2. 5. We suggest that ambulatory anesthesia should be more carefully planned, organized, and managed.

B 형 간염 Virus-Associated Hemophagocytic Syndrome 1 예

김진우,임경수,최영미,정인석,박두복,김호균,정영기 대한내과학회 1991 대한내과학회지 Vol.40 No.6

Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic generalized histiocytic proliferation with marked hemophagocytosis associated with systemic viral infections such as Epstein-Barr virus, cytomegalovirus, adenovirus, herpes virus. etc. High fever, liver dysfunction, coagulation abnormality, and peripheral blood cytopenias are characteristic findings. Hepatosplenomegaly, lymphadenopathy, bilateral pulmonary infiltrations, and skin rash are often present. We report a case of Hepatitis B virus-associated hemophagocytic syndrome with a brief review of literature.

소장내용물의 위내역류 및 위내용물 배출시간에 관한 연구

김진호,박승철,이형호,안일민,박영태,김열흥,이창흥 대한내과학회 1986 대한내과학회지 Vol.30 No.2

Radionuclide enterogastric scintigraphy was done with (99m)Tc-DISIDA and (111)In-DTPA in 35cases; control group 5, gastric ulcer group 6, subtotal gastrectomy with Billroth g group 5, and functional gastrointestinal disorder group with or without grossly mixed bile in the gastric juice 19 cases. The results were: 1) Enterogastric reflux was very significantly increased in the subtotal gastrectomy with Billroth II group (p$lt;0, 001), 2) Gastric emptying was significantly delayed in the functional gastrointestinal disorder groups with or without grossly mixed bile (p$lt;0.05, p$lt;0. 001). 3) Enterogastric reflux was not significantly increased in the gastric ulcer group. 4) Enterogastric reflux was not significantly different between the functional gastrointestinal groups with or without grossly mixed bile in the gastric juice. 5) Inverse correlation between the gastric emptying indices and the enterogastric reflux indices was not proved (r=-0.37).

가토에서 CCNU 로 유발된 골수 저형성증의 혈액학적 소견과 골수스캔의 변화에 관한 연구

김승택,이명철,최두혁,고창순,김병국,이문호,박선양,최성재,김노경,최영희 대한내과학회 1986 대한내과학회지 Vol.30 No.1

To understand systematically the hematological changes including the bone marrow changes in chemotherapeutic agent-induced bone marrow hypoplasia and to define the relationship between hematological and bone marrow scan findings and prognosis of the hypoplasia, CCNU (lomustine) was given orally to 44 rabbits to induce hypoplasia of the bone marrow. And serial changes of peripheral blood and bone marrow findings and (111)In Cl(3)((111)In scan)/(99m)Tc tin colloid bone marrow scan((99m)Tc scan) were checked before and after induction of hypoplasia. With assessment of 28 evaluable rabbits, the following results were obtained: 1) Significant hypoplasia of the bone marrow developed around day 4 of CCNU administration and recovered around day 14(cellularity 51,4±13.5% and 24. 5±14.97o before and after CCNU respectively, p<005). Megakaryocyte count was significantly depressed from 95.67,26% to 36.7$gt;31.82%(P$lt;0.005). M: E ratio was decreased from 162±1.19 to 0, 0.5$lt;0. 43(p±0.005). Shift to left(475), maturation a(40%), naked nucleus and degenerated cells(20%), increase of lymphocytes(47%), monocytes and reticulum cells were also found. 2) The uptake ratio of the 99(m)Tc tin colloid bone marrow scan was markedly increased in contrast to the depression of the bone marrow(4.4±2.12 and 14.1±7.06 before and 4 days after CCNU, respectively, p40. 005). Tc scan uptake ratio was inversely related to the cellularity(r=-0.442, p$lt;0.05) and megakaryocyte number of the bone marrow(r= 0.89, p< 0.01) and peripheral blood granulocyte (r = 0. 54. Pg0.01) and platelet count(r=0.40, p$lt;0.05). There was not significant correlation between (111)In scan uptake ratio and hematologic parameters. 3) The amplitude of the change of the (99m)Tc scan uptake ratio was significantly related to the prognosis of the rabbits with experimentally induced hypoplasia of the bone marrow(dead 5.1±2,67, survivors 2,5±0.96, P<0.01). The change of the (111)In scan uptake ratio was not related to the prognosis of these rabbits. In experimentally induced rrow hypoplasia, morphologic changes in addition to the numerical changes of the bone marrow elements were observed. And serial (99)Tc scan of the bone marrow appears to be helpful assessing the severity and predicting the outcome of bone marrow hypoplasia.

급성췌장염에 의한 췌장가성남종에서 내시경적 배액술후 발생한 췌장가성남종과 십이지장 및 대장에 발생한 내부 췌장루 1예

김연수,이문성,김진오,조영덕,이영홍,봉형근,조주영,이준성,심찬섭,황성규,전기원,변재호,장재영 대한소화기학회 1996 대한소화기학회지 Vol.28 No.1