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Choi, Young Deuk,Ham, Won Sik,Kim, Won Tae,Cho, Kang Su,Lee, Joo Hyoung,Cho, Soung Yong,Seo, Ju Wan,Jin, Ok Hyun Mary Ann Liebert 2009 Journal of endourology Vol.23 No.6
<P>PURPOSE: To evaluate the efficacy and safety of single-session OK-432 sclerotherapy for the treatment of renal cysts. MATERIALS AND METHODS: From October 2005 to November 2006, 48 patients (61 simple renal cysts) were included in the study. Indications were determined as flank discomfort (n = 37) or patient reassurance due to increasing size (n = 11). The simple renal cysts were aspirated under ultrasonography (US), at which point OK-432 was injected into the cyst. Follow-up was performed with US or computed tomography scan every 3 months until 1 year. Complete regression of the renal cyst or more than 70% reduction in size with no symptoms indicated a successful treatment. RESULTS: Among 61 renal cysts of 48 patients, the overall success rate was 98.4%. Complete regression occurred in 46 cysts (75.4%), and more than 90% reduction in size occurred in 6 cysts (9.8%). A size reduction of 80% to 90% and 70% to 80% occurred in five (8.2%) and three cysts (4.9%), respectively. A size reduction less than 70% occurred in only one cyst (1.6%). The success of cyst regression was correlated with cyst volume. Clinical symptoms resolved in 100% of patients with symptomatic cysts, and there was no enlargement of the aspirated cysts at the 1-year follow-up. After the procedure, there were only some minor complications, such as mild fever, flank pain, and leukocytosis, which subsided with the conservative treatment. CONCLUSIONS: Percutaneous OK-432 sclerotherapy is simple, safe, and effective, and it can be an alternative first-line therapy for simple renal cysts.</P>
Progastrin-releasing peptide as a diagnostic and therapeutic biomarker of small cell lung cancer
오형주,( Ha Young Park ),( Tae Ok Kim1 ),( Chul Kyu Park ),( Hong Jun Shin ),( Hee Jung Ban ),( In Jae Oh ),( Yong Soo Kwon ),( Yu Il Kim ),( Sung Chul Lim ),( Young Chul Kim ),( Soo Hyun Kim ),( Myung G 대한결핵 및 호흡기학회 2015 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.120 No.-
Background: Progastrin-releasing peptide (proGRP) is a recently identified biomarker of small cell lung cancer (SCLC). We aimed this study for evaluating the usefulness of automated proGRP measurement for diagnosis and treatment monitoring in patients with SCLC. Methods: From January 2011 to December 2013, plasma samples were prospectively collected from 452 [213 non-small cell lung cancer (NSCLC), 104 SCLC, 135 other diseases] patients visited for tissue diagnosis and tested by two-step automated immunoassay using the ARCHITECT proGRP assay kit (Abbott Diagnostics, USA). The cutoff level of proGRP was set at 63 pg/mL. Results: The mean proGRP was higher in SCLC (1823.0 ± 2684.0 pg/mL) than in NSCLC (61.0 ± 341.7 pg/mL) and other diseases (51.5 ± 222.6 pg/mL, p<0.001). The sensitivity of proGRP was 85.7% (90/105) in SCLC and 11.8% (25/212) in NSCLC. The specificity was 90.2%, positive predictive value was 72.5%, and negative predictive value was 95.4% in SCLC. The mean proGRP was higher in extensive disease (2158.1 ± 2980.6 pg/mL) than in limited disease (901.4 ± 1216.0 pg/mL, p=0.033). Among the 39 patients with SCLC could be followed, the mean proGRP levels of 23 responders were significantly decreased after chemotherapy (from 1651.5 ± 1386.4 pg/mL to 290.0 ± 524.8 pg/mL, p<0.001), whereas those of the 16 non-responders were not. (from 572.5 ± 790.3 pg/mL to 494.4 ± 610.9 pg/mL, p=0.583). Conclusion: Plasma proGRP could be a useful biomarker of SCLC for diagnosis and treatment monitoring. And the initial level may represent the tumor extent of SCLC.
Prediction of skin penetration of Bifenthrin using in vitro micro-pig skin model
Ji-Hyun Bang(Ji-Hyun Bang),Hyun-Ok Ku(Hyun-Ok Ku),Byung-Suk Jeon(Byung-Suk Jeon),Hyobi Kim(Hyobi Kim),Kwang-Jick Lee(Kwang-Jick Lee),Yong-Sang Kim(Yong-Sang Kim),Hee Yi(Hee Yi) 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-
Pretilt Angles Transition via Mixture Liquid Crystal System
Kim, Jeong-Hwan,Chun, Ji-Yun,Park, Hong-Gyu,Na, Hyun-Jae,Kim, Young-Hwan,Kim, Byoung-Yong,Ok, Chul-Ho,Hwang, Jeong-Yeon,Han, Jeong-Min,Park, Yong-Pil,Seo, Dae-Shik Informa UK (TaylorFrancis) 2010 Molecular Crystals and Liquid Crystals Vol.529 No.1
Continuous Pretilt Angle Controlled No-Bias-Bend Pi Cell via Blended Polyimide Liquid Crystal System
Kim, Dai-Hyun,Park, Hong-Gyu,Kim, Young-Hwan,Kim, Byoung-Yong,Ok, Chul-Ho,Hwang, Jeong-Yeon,Han, Jeong-Min,Park, Yong-Pil,Seo, Dae-Shik Informa UK (TaylorFrancis) 2010 Molecular Crystals and Liquid Crystals Vol.529 No.1
Kim, Sung Hun,Yang, Hyun Ok,Sohn, Young Chang,Kwon, Hak Cheol Society for General Microbiology 2010 International journal of systematic and evolutiona Vol.60 No.12
<P>A marine bacterium, strain KME 001(T), was isolated from the siphon tissue of a marine ascidian, Halocynthia roretzi, collected off the coast of Gangneung, Korea. Strain KME 001(T) was a Gram-positive, aerobic, non-spore-forming, rod-shaped and non-motile bacterium. Phylogenetic analysis using 16S rRNA gene sequences revealed that strain KME 001(T) clustered with the genus Aeromicrobium and was closely related to Aeromicrobium ginsengisoli, Aeromicrobium erythreum and Aeromicrobium ponti with 97.7, 97.6 and 97.5?% sequence similarities, respectively. The strain was capable of growth at a variety of temperatures (10-42C) and over a broad pH range (5.0-10.0). NaCl was required for robust growth of the strain. The diagnostic diamino acid of the cell-wall peptidoglycan was ll-diaminopimelic acid. The predominant menaquinone was MK-9(H(4)). The predominant fatty acids were C(18?:?1)ω9c, C(16?:?0) and 10-methyl C(18?:?0). The DNA-DNA hybridization analyses showed that DNA-DNA relatedness values between strain KME 001(T) and its nearest neighbours, A. ginsengisoli KCTC 19207(T), A. erythreum KCCM 41104(T) and A. ponti KACC 20565(T), were 49.6, 57.1 and 63.5?%, respectively. The DNA G+C content of strain KME 001(T) was 75.9mol%. Chemical investigation of the liquid culture medium of strain KME 001(T) led to the isolation of taurocholic acid as a major secondary metabolite. On the basis of phylogenetic and phenotypic data, strain KME 001(T) is classified as representing a novel species of the genus Aeromicrobium, for which the name Aeromicrobium halocynthiae sp. nov. is proposed. The type strain is KME 001(T) (=JCM 15749(T)=KCCM 90079(T)).</P>