부인암 환자에서 발견되는 대장 선종의 특징

전정현,정성애,김성은,이종수,남승현,신정은,문혜성,김승철,유권 梨花女子大學校 醫科大學 醫科學硏究所 2003 EMJ (Ewha medical journal) Vol.26 No.1

연구목적 : 2형 Lynch 증후군에 대한 관심이 높아지면서 부인과 종양 환자에게 대장암과 대상 선종의 검사 필요성이 언급되어지고 있다. 본 연구에서는 본원의 부인과 종양 환자에서 병기 결정을 위해 시행되어지는 S상 결장경 검사에서 발견되는 대상 선종의 특징을 알아보고자 하였다. 방법 : 1993년 9월부터 2001년 3월까지 본원에서 부인과 종양을 진단받고 대장 증상 없이 병기 결정을 위해 S상 결장경검사를 시행한 187명을 대상으로 하였고(자궁경부암 139명, 난소암 35명, 자궁 내막암 13명) 정상대조군으로는 대장 증상 없이 건강 검진 목적으로 대장경 검사를 시행한 58명을 대상으로 하였다. 결과 : 부인과 종양 환자 187명 중 21명에서 대장 선종이 발견되었고(11.2%) 다발성 선종이 있어 모두 26예의 선종이 관찰되었다. 정상 대조군 58명에서는 3명에서 선종이 발견되었고(5.2%) 다발성 선종은 없었다. 부인과 종양 중 자궁 내막암 환자군에서 선종의 빈도는 38.5%로 정상 대조군에 비해 통계학적으로 유의하게 많았다. 진행성 선종의 빈도도 자궁 경부암 환자 12.5%, 난소암 환자 25.5%, 정상 대조군 33.3%에 비해 자궁 내막암 환자 83.5%로 유의하게 많았다. 부인과 종양의 선종 위치는 직장이 23.1%, S상결장이 76.9%였다. 결론 : 부인과 종양 환자의 대장 선종 빈도는 정상 대조군에 비해 많은 경향을 보였으나 통계학적 의의는 없었다. 그러나 자궁 내막암 환자군에서는 다른 부인과 종양 환자나 정상 대조군에 비해 유의하게 많은 선종과 진행성 선종의 빈도를 부였다. 따라서 부인과 종양 환자에게 대장경 검사를 통한 대장 선종 유무 검사가 필요하리라 생각된다. Objectives : In Lynch syndrome Ⅱ, colon cancer was associated with endometrial and ovarian cancer. The aim of this study was an evaluation for the clinicopathologic characteristics of rectosigmoid adenomas on preoperative sigmoidoscopy in gynecologic cancer patients. Methods : A total 187 gynecologic cancer patients(139 cervical, 35 ovarian, 13 endometrial cancer) and 58 normal controls were reviewed sigmoidscopic finding and pathologic reports retrospectively from September 1993 to March 2001. Results : The mean age of gynecologic cancer patients was 54(38-82) year-old and normal controls was 50(20-68) year-old. Total 26 adenomas were in 21 patients(11.2%) and 3 adenomas were in 3 normal controls(5.2%). The incidence of adenomas was 9.4% in cervical cancer, 8.6% in ovarian cancer and 38.5% in endometrial cancer. Multiple adenomas were in 5 gynecologic cancer patients and 0 normal controls. The incidence of advanced adenoma was 12.5% in cervical cancer, 25.5% in ovarian cancer, 83.5% in endometrial cancer and 33.3% in normal controls. The location of adenoma was 23.1% in rectum and 76.9% in sigmoid colon. Conclusion : The incidence of adenomas and multiple adenomas were higher in gynecologic cancer patients than normal controls but not significantly. The incidence of advanced adenoma and adenomas were significantly higher in endometrial cancer than normal controls. Colonoscopic evaluation of whole colon will be recommanded in gynecologic cancer than sigmoidoscopy.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

안구의 비색소성 모양체 상피에서 발생한 유두상 선암종 -1예 보고-

최현주,최영진,이연수,이은정,강석진,김병기,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.12

창의성과 학업성적이 설계교육 성과에 미치는 영향

성은현,신문기 대한건축학회 2004 대한건축학회논문집 Vol.20 No.9

This research aimed to study the relationships between the divergent thinking, the creative personality, the general knowledge, the knowledge of major field and the ability of architectural design The 191 students majoring architecture In the university in Choong-Nam province participated In tins study The subjects were divided into two groups, high grade (the junior and the senior group) and low grade one (the freshman and the sophomore group) Each group was divided again into two sub-groups according to architectural design ability, high ability group and low ability one We used i-test and stepwise multiple near regression for analysing the data of each group The results were as follows First, m the low grade group, the high ability of architectural design group gamed significantly high scores m the creative personality, the knowledge of major field and the general knowledge than low ability group In the high grade group, the high ability of architectural design group gamed significantly high scores in the creative personality, the divergent thinking, the knowledge of major field and the general knowledges than low ability one Second, m the low grade group, the general knowledge and the knowledge of major field were the significant predictors of the ability of architectural design In the high grade group, the knowledge of major field and creative personality were the significant predictors of the ability of architectural design Finally, limitations of this study and the directions for future research were discussed.

염증성 근섬유모세포종의 증례보고

은상아,박혁,차인호,김현실,정호걸,김기덕,박창서 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.3

The inflammatory myofibroblastic tumor (inflammatory pseudotumor) is a rarely occurring soft tissue lesion of unknown etiology. It can be of any location, but commonly it is found in lungs. It has been considered as a nonneoplastic reactive inflammatory lesion, but nowadays, confusion and dispute about its character is increasing due to its high recurrence rate and metastasis. We present a patient who had been diagnosed with an inflammatory pseudotumor in the right maxilla area, 1 year before visiting our hospital. After that, her pain and swelling did not resolved and she visit our hospital. On radiographic examination, aggressively infiltrative growth of the lesion with destruction of adjacent bony structure was noted. We found unusual aggressiveness of the inflammatory myofibroblastic tumor of the head and neck region. Because the typical behavior of the inflammatory myofibroblastic tumor is not defined yet, we recommend the surgical excision of the lesion and close follow-up.

IEEE 802.11기반의 애드 혹 네트워크의 효율적인 동시적 전송

공현표,김은성,김두용 순천향대학교 산업기술연구소 2007 순천향 산업기술연구소논문집 Vol.13 No.1

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5종의 치주질환균에 대한 프로폴리스의 항균효과

이은지,김소민,박소민,박복리,홍성익,김현정 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

Since the oral cavity is directly connected to the outside, it is an important site for microbial invasion, and since it is an environment that is nutritionally and physiologically easy to multiply bacteria, many bacteria always form bacteriological flora in the oral cavity. And propolis is a natural treatment used in many health food stores in various forms for local treatment. This study analyzes the changes in the activity of five oral microorganisms before and after consumption of propolis for various age groups to find out how propolis, which shows the efficacy of anti-inflammatory, antibacterial, and immune sensitization, affects oral microorganisms. Five types of bacteria possessed by periodontal disease patients were specified and digitized targeting the public person, and then before and after propolis intake was compared, and the levels of periodontal disease bacteria in the intake group and the non-consumption group were compared. As a result of comparing the patterns before ingestion (0 week) and after ingestion (3 week) in the oral bacteria analysis, it was confirmed that the bacteria decreased overall except for the five populations in the propolis intake group. In contrast, in the comparative group that did not intake propolis, the bacteria of five periodontal disease increased except for the four populations. What can be seen from this result is that propolis is effective in reducing bacteria in five types of periodontal disease. In order to use propolis as a food for preventing periodontal disease and to get a better effect, further research is needed to find out the mechanism of antibacterial action in propolis compounds.

유방암과 관련된 부수종양성 Stiff-Person Syndrome 1예

방현,이상암,최은정,김광국,박성혜 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

가토의 뇌동맥류 모형에서 모동맥 및 동맥류 협자에 따른 동맥류 내압의 변화 :기초 연구

김은영,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4