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      • 신경섬유종증 환자에게서 발생한 특발성 혈소판 감소증 1예

        권세훈,김형호,강지인,장재혁,원경준,장재현,김상용,배학연 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

        Idiopathic thrombocytopenic purpura is a disease characterized by thrombocytopenia in peripheral blood with positive anti-platelet antibody titer, no splenomegaly, the presence of megakarocyte. The causes of idiopathic thrombocytopenic purpura were usually related to autoimmune disease, infection and drugs. A 46-years-old man was admitted for evaluation of abdominal mass. He has many cafe-au-lait spots and nodules in almost skin for 30 years. Several years ago, he palpated mass in Lt. inguinal area. hIe has known the abdominal mass after checking abdomen CT in local clinic and visited our hospital for evaluation of abdominal mass. At admission, laboratory tests showed hemoglobin 12.5 g/dL, hematocrit 38.4 %, WBC 5,460 /㎣ (neutrophil 64.5%, lymphocyte 21.7%, monocyte 4.1%, eosinophil 5.4%), reticulocyte 0.7%, Platelet 52,000 /㎣, total protein 6.51 g/dL, albumin 3.80 g/dL, alkaline pohsphatase 161 IU/L, AST 110.7 IU/L, ALT 64.9 IU/L, total bilirubin 0.44 ㎎/dL, BUN 18.4 ㎎/dL, creatinine 0.79 ㎎/dL. Peripheral blood smear showed normocytic normochromic anemia, thrombocytopenia. Bone marrow aspiration smear showed normoplastic myeloid and erythroid precursor. The bone marrow biopsy section shows normocellular marrow (35%) for his age and mildly increasing myeloid cell lineage. We have experienced a case of idiopathic thrombocytopenic purpura in a patient being in neurofibromatosis and therefore reporting it with documentary records. 저자들은 신경섬유종증 환자에서 특별한 원인을 발견할 수 없었음에도 특발성 혈소판 감소증이 발생한 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

      • 교합성 골수강내 금속정으로 치료한 대퇴골 골절의 치료

        권칠수,안종국,김용욱,김진혁,정병현,성열보,강재철 인제대학교 1995 仁濟醫學 Vol.16 No.4

        대퇴골 간부 골절시 교합성 골수강내 금속정을 이용한 견고한 고정은 조기 관절 운동과 조기 체중부하가 가능한 보편적인 수술적 치료방법으로 그 사용이 증가하고 있다. 그리고 최근에는 골수강내 금속정이 대퇴골 간부 골절 뿐만 아니라 대퇴골의 근위부나 원위부에 치우친 골절이나 청소년기의 대퇴골 간부 골절의 치료에도 확대되고 있다. 본 논문은 대퇴골 골절 환자 54례를 대상으로 금속정 삽입술의 적응증의 확대와 그에 수반되는 문제점에 관하여 증례 분석 및 결과를 문헌 고찰과 함께 보고하고자 한다. The rigid internal fixation of femur shaft fracture with intramedullary nailing enables early joint motion and weight bearing. This procedure has been used with wide popularity because it is possible simultaneously to preserve the range of motion and to obtain the bone union. But in the proximal and distal femur fracture, the interlocking screws are too close to the fracture site, the rigid fixation cannot be achieved and when early weight bearing is permitted, failure of the metal is possible. Also, when femur fractures in the adolescence be treated with traction followed by casting, sometimes angular deformity and shortening may develope. These problems have solved to the use by intramedullary nailing. The authors reviewed and analyzed 54 cases of the fractures of femur treated by interlocking nails at Sang-Gye Paik Hospital from August 1989 to July 1992. The results were as follows ; 1.Among the 54 patients, male were 42 and female were 12. 2.The mean time of bone union was 19.3 weeks. 3.The authors usually used the closed locked nailing technique to fix the mid-shaft fracture of femur. In cases such as mid-shaft fracture combined wish proximal or distal femoral fracture, for the stability of fracture and the early mobilization, a reconstruction nail or modified nailing technique was used and an excellent bone union was obtained without any complication. 4.In a mid-shaft fractures of the femur in adolescents or young adult, the authors used interlocking nails of proper length or diameter by cutting-off the distal portion of the nail or by over-reaming of the too narrow medullary canal, and the outcome was favorable.

      • 전주기술을 이용한 로터리스크린 제조에 관한 연구

        권혁홍,박상호 대진대학교 2004 大眞論叢 Vol.11 No.-

        To simple the manufacturing process of rotary screen, this study was adopted electroforming technology and produced silicon rubber mandrel. Furthermore, to indicate the optimal condition for the acquisition of high-qualified rotary screen product, the experiment was executed with pH, time, sulfamate nickel solution according to density which were the main factors to decide the condition, then compared it with the product made by original "S" Company in Holland. As a result, the figure of Hole was more obvious and correct. Also the open size increased more than 2-3%.

      • 백두옹 에틸분획의 약효성분

        권혁상,황완균,김일혁 중앙대학교 약학연구소 1996 약학 논총 Vol.10 No.-

        The Pharmaco-Constituents of the Pulsatilla Koreana Roots, of which roots and rhizomes have been used for the treatment of evil heat, malaria, chill, fever, epistaxis and internal hemorrhoids etc. in Korean folk remedies. From the Ether extract of Roots, two triterpenoidal sapogenins were isolated and elucidated as ursolic acid and oleanolic acid based on their physico-chemical data and IR, EI-MS, ^13C-NMR, and ^1H-NMR analysis with authentics, respectively.

      • KCI등재

        Iridoid 화합물이 치수절단 후 잔존치수 조직에 미치는 영향

        권혁춘,박동성,손호현 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.2

        Aucubin, an iridoid glucoside, which is isolated form Aucuba japonica, has some biological effects. This study was to investigate the effect of aucubin on the remainig pulp tissues after pulpotomy. Mongrel dog's coronal pulps were mechanically exposed with a sterile round bur and excised with sterile sharp excarvator. After bleeding was controlled, in control group, Ca(OH)_2 powder was applied on the remaining pulps and the cavities were sealed with Z.O.E cement. In experimental group 1, mixed powder with Ca(OH)_2 and aucubin(1:1 by weight) was applied on the pulotomized pulp surfaces. After th cavities were covered with sterile aluminum foil, they were sealed with Z.O.E. cement. In experimental group 2, only aucubin powder was applied on the remaining pulps and then they were treated the same as experimental group 1. In the all groups, the pulps were histopathologically observed by light microscope at the time intervals of 1, 2 and 4 weeks after experiment. The results were as follows: 1. In control and experimental groups, mild vascular congestion and bleeding were found in most of the specimens. Less inflammatory infiltration was observed in experimental groups than in control group. 2. Dentin bridge formation was found after 1 week at both control and experimental group 1. Dentin birdge had discontinuous osteodentin like appearance of contained some dentin chips. In experimental group 2, dentin bridge was not seen. 3. The coagulation necrosis layer on the remaining pulp tissues was seen in all groups. In experimental group 2, the thickest layer was observed. And in control group, coagulation necrosis layer was similar as in experimental group 1.

      • KCI등재

        일반 교육-특수교육 완전 통합을 위한 기초 연구 : 탐구조사 An Exploratory Study

        권상혁,황윤한 국립특수교육원 1995 특수교육연구 Vol.2 No.-

        Total integration is the most ethical and humanistic way of teaching exceptional children. The purpose of this study were 1) to examine the problems in special education, 2) to investigate the reasons for being unable to integrate exceptional children with their non-handicapped peers, and 3) to obtain suggestions to accentuate total integration recommended by special education teachers. Thirty-seven elementary school special education teachers participated in this study. Problems in special education practice pointed by special education teachers vary from the lack of perceptions of educational leaders, teachers, students, and students to the education of quality special education teachers. Reasons for being unable to integrate exceptional children with their non-handicapped peers were also related to the problems in current special education culture. Special education teachers suggested various ways to accentuate total integration.

      • Urechis unicinctus 난세포의 인공수정에 의한 구조적 변화

        권혁제,김완종,신길상 순천향대학교 1994 논문집 Vol.17 No.3

        The artificial insemination in Urechis unicinctus oocyte revealed some fine structural changes under electron microscope. The degradation of surface coat, retraction of microvilli, fusion of cortical granules with oocyte membrane are the events of fine structural changes after the fertilization. At fertilization, the cortical granules of oocyte are transported from the inner cortex toward oocyte membrane. After the fusion, the contents of cortical granules are discharged into the perivitelline space, the extracelluar space which in future develops into fertilization membrane. There are some indications that the fertilization occur on the microvillous tip in U. uicinctus. Under light microscope, one of the evidences on the fertilization was the formation of fertilization cone, which seemed to sperm entry site, on membrane of round mature oocyte.

      • 불소가 첨가된 실리콘 산화막의 다층금속절연 특성에 관한 연구

        權大赫,南基泓,吳相光 慶一大學校 1997 論文集 Vol.14 No.2

        The characteristics of fluorinated silicon oxide (SiOF) films prepared by plasma enhanced chemical vapor deposition(PECVD) were discussed. The deposition of these films was carried out in the temperature range of 80 - 220℃ in a conventional parallel plate plasma reactor with 〈 ±3% uniformity by flowing 2 sccm of disilane (Si₂H6), 100 sccm of nitrous oxide (N₂O), and 20 sccm of tetrafluoromethane (CF₄). AS the deposition temperature increased from 80 to 220℃, the deposition rate of the films increased from 16.7 to 18.4 nm/min; meanwhile, the etch rate decreased from 2.69 to 1.48 nm/sec. The refractive index was 1.46 regardless of the deposition temperature. The Fourier transform infrared (FTIR) spectra of the films showed decreasing Si-O stretching wave number with increasing full width at half maximum (FWHM) as deposition temperature increased. The high frequency capacitance-voltage (C-V) measurements of the metal-oxide-semiconductor (MOS) capacitors fabricated using the films showed increasing effective oxide charge density and decreasing dielectric constant with increasing deposition temperature. Deposition temperature of 180℃ resulted in films with the smallest dielectric constant of 3.75. These films showed an average breakdown strength of 9.14 MV/cm with 77.5% of the MOS capacitors having breakdown field strength ≥9.5 MV/cm

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