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The author presented a new method of intermaxillary fixation namely Kang s wiring The Kang s wiring has been already utilized to the mandibular fracture cases and obtained succesful result in General Hospital, klang, Ma!aysiar and paik Hospital, Inje Medical College Seoul. The author found the kang s wiring has proved it s efficiency and simplicity through his clinical experiences. The new wiring also caused less periodontal problem throughout the period of treatment compare than any other method.
발치와에 매식된 Hydroxyapatite가 발치창의 치유에 미치는 영향과 입자형 Hydroxyapatite의 조직 적합성에 관할 실험적 연구를 통하여 발치와에 매식된 Hydroxyapatite는 초기에 일시적인 이물반응을 보이며 발치창의 치유를 어느 정도 지연시키나, 그 이후 과정에서는 점차적으로 골조직의 형성을 촉진하고 정상적인 치유 과정을 보여 주고 있으며 치밀골에 의한 발치창의 치유 과정에서 뛰어난 조직 적합성을 보이는 것을 관찰할 수 있었다. 따라서 Hydroxyapatite는 발치후 치조정의 흡수 방지에도 좋은 결과를 얻을 수 있을 것으로 생각된다. The purpose of this study is to investigate the effect and the tissue integrity of hydroxyapatite granules which was implanted in the extraction sockets of mandibular anterior tooth of sprague Dawley rats. The specimen was taken after 1,2,3 days, 1,2,3,4 weeks and 3 months postoperatively. The author observed the following results. In the early phase, temporary foreign body reactions and delayed healing were observed, but in the late phase, the accelerated healing process of lamellated bone formation was observed and excellent tissue integrity of hydroxyapatite was confirmed.
치성상피성 종양에서의 PCNA, EGF, EGF-r의 분포 및 종양의 활성도에 관한 연구를 면역조직화학적 염색 방법으로 시행하였다. The purposes of this study were to assess proliferative activities and immunolocalization of proliferating cell nuclear antigen(PCNA), epithelial growth factor(EGF) and its receptor(EGF-r) in odotogenic tumors. 27 cases of ameloblastoma, 4 cases of AOT(adenomatoid odontogenic tumor), 5 cases of BEGOT(benign epithelial odontogenic ghost cell tumor) and 2 cases of PIOC(primary intraosseous odntogenic tumor) were retrived from the Department of Oral Pathology, College of Denistry, Seoul National University. The control was tooth follicle They were processed for Labelled Streptavidin Biotin methods. The primary antibodies used in this study were antibodies to PCNA, EGF and EGF-r. Following results were obtained. 1.In control group, inner enalmel epithelium, stellate and dental follicle showed positive reaction for PCNA. 2.In ameloblastoma, the peripheral cell of small follicle, casa cell of unisystic type and adjacent cell of granular cell showed strong positive reaction for PCNA. 3.In AOT, duct-like cells showed positive reaction for PCNA 4.In AIOC and BEGOT the penpheral cell of tumor cluster showed strong positive reaction for PCNA. 5.Ameloblastoma and AOT revealed negative reaction for EGF, EGF-r 6.Positive reaction of BEGOT and PIOC for EGF and EGF-r explained their malignancy potential.
The aim of this study to evaluate the microvascular alterations in salivary grand carcinoma after irradiations. Salivary gland carcinoma was induced in rats by inoculation of several amount of 7, 12-dimethylbenzan thracene power 2.5㎎, 5.0㎎ and 7.5㎎ respectively into rat submandibular gland. Microangiography was performed by talking soft x-ray with barium infusion, and by indian perfusion technique. The tumors were given a single does of 20 Gy(to obtain comparatively low grade irradiation does for is effect of dry desquamation of skin to enable the observation of the vascular changes of the tumor) using LINAC 4MeV Mitsubishi unit with field size of 3×3㎝ at 80 SSD. The does rate was 2.5 Gy per minute. The microangiography was performed prior to irradiation and at one, two, and four weeks after irradiation. The results are as follows. 1. The carcinoma was produced in all rats(100%) between 7 to 11 weeks, the amount of carcinogen was not always in proportion to the development of carcinogenesis, and the most appropriate group for the experiment was 5.0㎎ inoculated one. 2. The course of experimental carcinogensis was initiated by ductal proliferation and squamous metaplasia of ductal epithelium which was later transformed into keratocyst and finally turned into squamous cell carcinoma. 3. Before irradiation, the basis vasculature consisted of peripheral vascular pattern with central penetrating vessels. The peripheral pattern was always richer than that of the center. Irregular and tortuous vessels stretch form the periphery into the center of tumor mass. 4. In an early stage following irradiation, an increase in the number of smaller, tortuous vessels and decreased intervascular distances were observed in the central portion of tumor nest mass. 5. Later change of microvasculature after irradiation are increase in tortuousity, irregularity, narrowing, abrupt tapering, fragmentation, and extravasation These findings progressed after a lapse of time. 6. The change of vascular structure after irradiation such as vasculitis, endothelial swelling and thrombosis on histologic section were coincided with the microangiographic changes. 7. It is suggestive that the mechanisms of the post-irradiation changes of vasculature in the center or periphery of the tumor mass is the destruction of tumor cells and capillaries caused by direct radiation effect, and the progressive degenerative and destructive changes are due to usual residual tissue damage by irradiation. 8. The vascular alterations by irradiation can cause the disruption of blood flow and it can be considered as one of the most effective suppressive factor of tumor growth. 9. The post-irradiative hyalinzation of the connective tissue surrounding the tumor tissue was one of the inhibitory factor of the tumor dissemination and cause of decrease of vascularity. 10. The granulation tissue formation outward the hyalinized zone surrounding the tumor tissue was the reactive feature against the post irradiative central tumor necrosis.
구강 내에는 많은 종류의 치계 낭종이 발생하고 있다. 이중 치성각화낭종은 10%정도를 차지한다. 저자는 1980년부터 1984년까지 만 5년간 치성각화낭종으로 판명된 49예의 연령 및 성별 분포 부위별 발생 상황, 재발율 등을 임상병리학적으로 분석 평가하였다. 이들의 재발율은 전체 환자의 12.2%로서 다른 치계 낭종에 비해 월등히 높은 수치를 보였다. 따라서 치성각화낭종의 경우에는 재발율을 감소시키기 위하여, 채택된 수술 방법이 매우 중요한 것으로 제시되었다. 이러한 결과는 향후 치성각화 낭종의 관리에 참고가 될 것으로 기대되어 문헌적 고찰과 함께 보고하는 바이다. The author has reviewed, clinically and histopathologically, 49 cases of odontogenic keratocysts which were collected at the dept. of dentistry, Inje Medical College, Paik Hospital, Seoul and the infirmary of dental school, SNU, for 5 years. (Jan. 1, 1980 - Dec. 31, 1984) The results were as follows 1.On the sex predilection, male was 59.271 (29 cases), female was 40.8% (20 cases). The ratio of male to female was 1.5:1. The peak incidence was in second decade (17 cases) and average age was 31.8 years old. 2.13 cases (26.5%) occurred in the maxilla and 36 cases (73.5%) occurred in the mandible, especially in the molar and ascending ramps area. 3.Recurrence rate was 12.2%. 4.There were no characteristics radiologically.