Teaching Present Perfect Aspect to EFL Students Using Translated Writing Methods

Byun Hyewon 한국통번역교육학회 2017 통번역교육연구 Vol.15 No.2

Present perfect aspect does not exist in Korean language and learning this aspect has always been a challenge for Korean EFL learners. Often gap filling and multiple questions are used after the class period, nonetheless successfully completing the tests do not reflect the full acquisition of this aspect for the learners. Present perfect aspect is commonly used in news reports in real life and research indicated that nearly 70% of the random news articles used present perfect than simple past. Therefore using news articles with the translated method should be an effective way to teach the EFL learners. Study found that multiple choice and gap filling tasks were not able to reflect the learners’ acquisition and meaningful differences were found between the traditional two tasks and the translated writing method using the news article. These findings could be applied to classroom settings not only during grammar lessons but also during writing classes where extended composition is required. Expanded studies could also be applied to other perfect aspects with various subjects not limiting to news articles.

Kaposi’s Sarcoma-associated Herpesvirus Open Reading Frame (ORF) 50 Transactivates K8 and ORF57 Promoters via Heterogeneous Response Elements

Hyewon Byun,Yousang Gwack,Seungmin Hwang,최준호 한국분자세포생물학회 2002 Molecules and cells Vol.14 No.2

Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) belongs to the human gammaherpesvirus family that undergoes both lytic and latent life cycles in host cells. Open reading frame (ORF) 50 is the most important protein in reactivation to lytic phase and functions as a strong transcriptional activator of the early and late genes of KSHV. Since transactivation of promoters by ORF50 is achieved via response elements, we have at-tempted to identify ORF50 response elements in K8 and ORF57 promoters of KSHV by transient transfec-tion assays with deletion mutants. Our data reveal that specific regions within the K8 (74661-74760) and ORF57 (81851-81931) promoters contain ORF50 re-sponse elements, which are heterogeneous, unlike those of Epstein-Barr virus and Herpesvirus saimiri. We additionally identify an AP-1 binding site at the ORF57 promoter between 81882 and 81889, and show that AP-1 participates in ORF57 promoter activation by ORF50. Our findings collectively indicate that ORF50 activates various viral proteins through both direct binding and cellular transcriptional factor-mediated mechanisms.

Using Automated Translating Machine to Encourage Target Vocabulary Learning During COVID-19

변혜원(Byun, HyeWon) 한국통번역교육학회 2021 통번역교육연구 Vol.19 No.2

The outbreak of COVID-19 has dramatically changed the dynamics of learning environment. Various researches have examined the implications and impacts of such changes and the results were met with mixed findings. Although the learners inevitably preferred face to face interaction and direct communication, under the circumstances they were willing to continue with the current devices if multiple modes of communication devices could be added to the current environment. The paper aimed to utilize the use of Automated Translating Machines (ATM), such as Naver Papago and Google Translator, to learners and to examine whether such devices could further aid the learners under such circumstances. Results showed that the high proficiency group only used the ATMs for reference purposes and such devices did not yield meaningful findings even with certain target vocabularies. However, low proficiency group learners were able to utilize the device to learn certain target vocabularies better than the conventional vocabulary learning method. This shows that ATMs can be utilized with the online-learning to teach certain target vocabularies to the low proficiency group learners.

Differential effects of blood insulin and HbA1c on cerebral amyloid burden and neurodegeneration in nondiabetic cognitively normal older adults

Byun, Min Soo,Kim, Hyun Jung,Yi, Dahyun,Choi, Hyo Jung,Baek, Hyewon,Lee, Jun Ho,Choe, Young Min,Sohn, Bo Kyung,Lee, Jun-Young,Lee, Younghwa,Ko, Hyunwoong,Kim, Yu Kyeong,Lee, Yun-Sang,Sohn, Chul-Ho,Woo PERGAMON PRESS LTD 2017 NEUROBIOLOGY OF AGING Vol. No.

<P><B>Abstract</B></P> <P>We tested the hypothesis that lower insulin or higher glycated hemoglobin (HbA1c) levels in blood are associated with increased cerebral beta amyloid (Aβ) deposition and neurodegeneration in nondiabetic cognitively normal (CN) older adults. A total of 205 nondiabetic CN older adults underwent comprehensive clinical assessment, [<SUP>11</SUP>C]Pittsburgh compound B (PiB)-positron emission tomography (PET), [<SUP>18</SUP>F]fluorodeoxyglucose-PET, magnetic resonance imaging, and blood sampling for fasting insulin and HbA1c measurement. Lower blood insulin was significantly associated with increased Aβ positivity rates and decreased cerebral glucose metabolism in the AD-signature region. In contrast, higher HbA1c levels were not associated with Aβ positivity rates but were significantly associated with higher rates of having neurodegeneration in the AD-signature regions. Our results suggest different roles of insulin and HbA1c in AD pathogenesis, in that decreased blood insulin below optimal levels may contribute to increasing cerebral Aβ deposition and neurodegeneration whereas impaired glycemic control may aggravate neurodegeneration through a nonamyloid mechanism in nondiabetic CN older adults.</P>

Association of Cerebral Amyloidosis, Blood Pressure, and Neuronal Injury with Late-Life Onset Depression

Byun, Min Soo,Choe, Young Min,Sohn, Bo Kyung,Yi, Dahyun,Han, Ji Young,Park, Jinsick,Choi, Hyo Jung,Baek, Hyewon,Lee, Jun Ho,Kim, Hyun Jung,Kim, Yu Kyeong,Yoon, Eun Jin,Sohn, Chul-Ho,Woo, Jong Inn,Lee, Frontiers Media S.A. 2016 FRONTIERS IN AGING NEUROSCIENCE Vol.8 No.-

<P>Previous literature suggests that Alzheimer's disease (AD) process may contribute to late-life onset depression (LLOD). Therefore, we investigated the association of LLOD with cerebral amyloidosis and neuronal injury, the two key brain changes in AD, along with vascular risks. Twenty nine non-demented individuals who first experienced major depressive disorder (MDD) after age of 60 years were included as LLOD subjects, and 27 non-demented elderly individuals without lifetime experience of MDD were included as normal controls (NC). Comorbid mild cognitive impairment (MCI) was diagnosed in 48% of LLOD subjects and in 0% of NC. LLOD, irrespective of comorbid MCI diagnosis, was associated with prominent prefrontal cortical atrophy. Compared to NC, LLOD subjects with comorbid MCI (LLOD<SUB>MCI</SUB>) showed increased cerebral <SUP>11</SUP>C-Pittsburg compound B (PiB) retention and plasma beta-amyloid 1–40 and 1–42 peptides, as measures of cerebral amyloidosis; and, such relationship was not observed in overall LLOD or LLOD without MCI (LLOD<SUB>woMCI</SUB>). LLOD subjects, particularly the LLOD<SUB>woMCI</SUB>, had higher systolic blood pressure (SBP) than NC. When analyzed in the same multiple logistic regression model that included prefrontal gray matter (GM) density, cerebral amyloidosis, and SBP as independent variables, only prefrontal GM density showed a significant independent association with LLOD regardless of MCI comorbidity status. Our findings suggest AD process might be related to LLOD via prefrontal neuronal injury in the MCI stage, whereas vascular processes—SBP elevation, in particular—are associated with LLOD via prefrontal neuronal injury even in cognitively intact or less impaired individuals.</P>

Smart Phone-based Luminance Measurement

Hyewon Song,Yungcheol Byun 한국콘텐츠학회 2015 한국콘텐츠학회 ICCC 논문집 Vol.- No.-

Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer’s Disease: Methodology and Baseline Sample Characteristics

MinSoo Byun,Dahyun Yi,JunHo Lee,YoungMin Choe,BoKyung Sohn,JunYoung Lee,HyoJung Choi,Hyewon Baek,YuKyeong Kim,YunSang Lee,ChulHo Sohn,Inhee MookJung,Murim Choi,YuJin Lee,DongWoo Lee,SeungHo Ryu,ShinGy 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.6

Objective-The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer’s disease (KBASE) aimed to recruit 650 individuals, aged from 20 to 90 years, to search for new biomarkers of Alzheimer’s disease (AD) and to investigate how multi-faceted lifetime experiences and bodily changes contribute to the brain changes or brain pathologies related to the AD process. Methods-All participants received comprehensive clinical and neuropsychological evaluations, multi-modal brain imaging, including magnetic resonance imaging, magnetic resonance angiography, [11C]Pittsburgh compound B-positron emission tomography (PET), and [18F]fluorodeoxyglucose-PET, blood and genetic marker analyses at baseline, and a subset of participants underwent actigraph monitoring and completed a sleep diary. Participants are to be followed annually with clinical and neuropsychological assessments, and biannually with the full KBASE assessment, including neuroimaging and laboratory tests. Results-As of March 2017, in total, 758 individuals had volunteered for this study. Among them, in total, 591 participants-291 cognitively normal (CN) old-aged individuals, 74 CN young- and middle-aged individuals, 139 individuals with mild cognitive impairment (MCI), and 87 individuals with AD dementia (ADD)-were enrolled at baseline, after excluding 162 individuals. A subset of participants (n=275) underwent actigraph monitoring. Conclusion-The KBASE cohort is a prospective, longitudinal cohort study that recruited participants with a wide age range and a wide distribution of cognitive status (CN, MCI, and ADD) and it has several strengths in its design and methodologies. Details of the recruitment, study methodology, and baseline sample characteristics are described in this paper.

고용불안정이 정신건강에 미치는 영향: 고용상태 변화 유형과 우울의 인과관계 추정

변금선 ( Byun Geumsun ),이혜원 ( Lee Hyewon ) 한국보건사회연구원 2018 保健社會硏究 Vol.38 No.3

본 연구는 한국복지패널자료의 18세 이상 65세 미만 임금근로자를 대상으로 고용불안정이 우울에 미치는 영향을 확인하였다. 비정규직 규모가 점차 증가하고 있고, 고용유형의 다변화로 고용불안정이 일상화되고 있지만 고용불안정의 영향, 특히 정신건강에 미치는 영향에 대해서는 충분한 연구가 이루어지지 않았다. 본 연구는 한국복지패널자료 6차(2010년)와 7차 자료(2011년)의 근로연령 임금근로자를 대상으로 2개 연도 사이의 고용상태 및 고용상태 변화가 우울수준(CES-D)에 미치는 영향을 분석하였다. 도구변수추정과 성향점수매칭(PSM)을 적용해 고용불안정과 우울간의 역인과관계로 인한 내생성 문제를 해결하고자 했다. 분석결과, 고용불안정은 우울수준을 증대시키는 것을 확인할 수 있었다. 특히, 현재 고용상태보다는 고용상태의 변화가 우울수준에 영향을 미치는 주된 요인이었으며, 고용불안정의 유형별 분석에 있어서는 정규직에서 비정규직으로 이동 혹은 실직 집단이 정규직 유지 집단에 비해 우울수준이 높은 것으로 나타났다. 이러한 결과는 내생성을 제거하였을 때, 기존 연구에서 제한적으로 확인된 고용불안정과 우울의 인과관계가 더욱 명확해질 수 있음을 보여준다. 고용불안정으로 인한 정신건강 문제를 완화하기 위한 적극적 정책 개입이 필요하다. This study examined the effect of employment instability on depression among wage earners aged 18 to 65 years using the Korean Welfare Panel Study (KOWEP) data. Employment instability is becoming more common with the increase in irregular workers and the diversification of employment types. However, previous studies have not fully investigated the effect of employment instability. This study assessed the effect of changes in employment status between 2010 and 2011 on the level of depression (CES-D) in 2011. We controlled for the endogeneity due to reverse causation and selection bias by applying instrumental variable estimation and propensity score matching. As a result, employment instability has an significant effect on increased level of the depressive symptom. In particular, the unemployed and those who moved from regular to irregular jobs had a higher level of depression than those in regular employment. This result shows the social causation between employment instability and depression. Active policy intervention is necessary to deal with the mental health problems of precarious workers.

다층 퍼셉트론을 이용한 전력소비 예측

송혜원(Hyewon Song),J. T. Lalis,B. D. Gerardo,변영철(Yungcheol Byun) 한국정보과학회 2017 한국정보과학회 학술발표논문집 Vol.2017 No.06

고해상도 네트워크를 이용한 도로 영역 검출 알고리즘

변승환(Seunghwan Byun),최우철(Woocheol Choi),이재민(Jaemin Lee),방혜원(Hyewon Bang),한영준(Youngjoon Han) 대한전기학회 2020 정보 및 제어 심포지엄 논문집 Vol.2020 No.10